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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Kismeth
 
Resource Report
Resource Website
50+ mentions
Kismeth (RRID:SCR_005444) Kismeth analysis service resource, data analysis service, production service resource, service resource A web-based tool for bisulfite sequencing analysis that was designed to be used with plants, since it considers potential cytosine methylation in any sequence context (CG, CHG, and CHH). It provides a tool for the design of bisulfite primers as well as several tools for the analysis of the bisulfite sequencing results. Kismeth is not limited to data from plants, as it can be used with data from any species. plant, methylation, bisulfite sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
PMID:18786255 Free for academic use, Contact for commercial use biotools:kismeth, OMICS_00602 https://bio.tools/kismeth SCR_005444 2026-09-12 01:01:37 55
TRANSFAC
 
Resource Report
Resource Website
100+ mentions
TRANSFAC (RRID:SCR_005620) TRANSFAC data or information resource, database Manually curated database of eukaryotic transcription factors, their genomic binding sites and DNA binding profiles. Used to predict potential transcription factor binding sites. Curated, eucaryotic, transcription, factor, genomic, binding, site, sequence, regulated, gene, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: Gene Regulation Databases
is related to: TRANSPATH
is related to: Babelomics
is related to: GeneTrail
works with: rVista
European Commission ;
German Ministry of Education and Research
PMID:12520026 Free, Freely available biotools:transfac, nif-0000-03576 http://www.biobase-international.com/pages/index.php?id=transfac, http://gene-regulation.com/pub/databases.html, https://bio.tools/transfac SCR_005620 2026-09-12 01:01:38 266
MRIcron
 
Resource Report
Resource Website
1000+ mentions
MRIcron (RRID:SCR_002403) MRIcron data processing software, data visualization software, software application, software resource Software tool as a cross-platform NIfTI format image viewer. Used for viewing and exporting of brain images. MRIcroGL is a variant of MRIcron. NIfTI, format, image, viewer, exporting, brain, image, processing, data, bio.tools is used by: XFSL: An FSL toolbox
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Biositemaps
is listed by: neurodebian
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Colour maps for brain imaging
has parent organization: University of South Carolina; South Carolina; USA
PMID:17583985
PMID:11568431
BSD License biotools:MRIcron, nif-0000-00122 https://sources.debian.org/src/mricron/, http://www.mccauslandcenter.sc.edu/mricro/, http://www.nitrc.org/projects/mricron, http://neuro.debian.net/pkgs/mricron.html, https://bio.tools/MRIcron SCR_002403 mricron - magnetic resonance image conversion viewing and analysis 2026-09-12 01:00:35 2312
SeqExpress
 
Resource Report
Resource Website
SeqExpress (RRID:SCR_007075) data processing software, software application, software resource A comprehensive analysis and visualization software package for gene expression experiments that provides: a number of clustering and analysis techniques; integrated gene expression and analysis result visualizations, integration with the Gene Expression Omnibus; and an optional data sharing architecture. GO is used to assign functional enrichment scores to clusters, using a combination of specially developed techniques and general statistical methods. These results can be explored using the in built ontology browsing tool or through the generated web pages. SeqExpress also supports numerous data transformation, projection, visualization, file export/import, searching, integration (with R), and clustering options. gene, gene expression, function, analysis, visualization, statistical analysis, windows, c#, gene function, chromosome location, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Gene Expression Omnibus
PMID:14988116 Free nlx_149285, biotools:seqexpress https://bio.tools/seqexpress SCR_007075 2026-09-12 01:00:57 0
RIKEN integrated database of mammals
 
Resource Report
Resource Website
RIKEN integrated database of mammals (RRID:SCR_006890) RIKEN integrated database of mammals data or information resource, database, portal THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 16, 2019.
A database that integrates not only RIKEN''''s original large-scale mammalian databases, such as FANTOM, the ENU mutagenesis program, the RIKEN Cerebellar Development Transcriptome Database and the Bioresource Database, but also imported data from public databases, such as Ensembl, MGI and biomedical ontologies. Our integrated database has been implemented on the infrastructure of publication medium for databases, termed SciNetS/SciNeS, or the Scientists'''' Networking System, where the data and metadata are structured as a semantic web and are downloadable in various standardized formats. The top-level ontology-based implementation of mammal-related data directly integrates the representative knowledge and individual data records in existing databases to ensure advanced cross-database searches and reduced unevenness of the data management operations. Through the development of this database, we propose a novel methodology for the development of standardized comprehensive management of heterogeneous data sets in multiple databases to improve the sustainability, accessibility, utility and publicity of the data of biomedical information.
integration, network, standardization, biomedical, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Functional Annotation of the Mammalian Genome
is related to: Cerebellar Development Transcriptome Database
is related to: Ensembl
is related to: Mouse Genome Informatics (MGI)
is related to: OBO
has parent organization: RIKEN Yokohama Institute; Kanagawa; Japan
Japanese Ministry of Education Culture Sports Science and Technology MEXT PMID:21076152 THIS RESOURCE IS NO LONGER IN SERVICE nlx_151886, biotools:riken https://bio.tools/riken SCR_006890 2026-09-12 01:00:57 0
epigenomix
 
Resource Report
Resource Website
1+ mentions
epigenomix (RRID:SCR_006407) epigenomix data processing software, software application, software resource Software package for the integrative analysis of microarray based gene expression and histone modification data obtained by ChIP-seq. The package provides methods for data preprocessing and matching as well as methods for fitting bayesian mixture models in order to detect genes with differences in both data types. epigenetic, gene expression, microarray, histone modification, chip-seq, classification, differential expression, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24403540 GNU Lesser General Public License, v3 biotools:epigenomix, OMICS_02205 https://bio.tools/epigenomix SCR_006407 epigenomix - Epigenetic and gene expression data normalization and integration with mixture models 2026-09-12 01:00:56 2
SOAPaligner/soap2
 
Resource Report
Resource Website
100+ mentions
SOAPaligner/soap2 (RRID:SCR_005503) SOAPaligner, SOAP2 data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 12,2024. Updated version of SOAP software for short oligonucleotide alignment that features in super fast and accurate alignment for huge amounts of short reads generated by Illumina/Solexa Genome Analyzer., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. next generation sequencing, alignment, short read, oligonucleotide, single-read, pair-end, resequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SOAP
PMID:19497933
DOI:10.1093/bioinformatics/btn025
THIS RESOURCE IS NO LONGER IN SERVICE biotools:soap2 https://bio.tools/soap2, https://sources.debian.org/src/soapaligner/ SCR_005503 2026-09-12 01:00:56 325
Pedigree-Draw
 
Resource Report
Resource Website
1+ mentions
Pedigree-Draw (RRID:SCR_008302) commercial organization, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 12,2024. Software application for pedigree drawing (entry from Genetic Analysis Software) gene, genetic, genomic, macos, bio.tools is listed by: Genetic Analysis Software
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: OMICtools
THIS RESOURCE IS NO LONGER IN SERVICE nlx_154520, OMICS_00213, SCR_010795 SCR_008302 PEDIGREE/DRAW 2026-09-12 01:00:58 1
COILS: Prediction of Coiled Coil Regions in Proteins
 
Resource Report
Resource Website
100+ mentions
COILS: Prediction of Coiled Coil Regions in Proteins (RRID:SCR_008440) data processing software, software application, software resource COILS is a program that compares a sequence to a database of known parallel two-stranded coiled-coils and derives a similarity score. By comparing this score to the distribution of scores in globular and coiled-coil proteins, the program then calculates the probability that the sequence will adopt a coiled-coil conformation. software, prediction, database, sequence, coil, globular, protein, probability, bio.tools, FASEB list is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1126/science.252.5009.1162 biotools:ncoils, OMICS_07850, nif-0000-30263 https://bio.tools/ncoils, https://sources.debian.org/src/ncoils/ https://sources.debian.org/src/ncoils/ SCR_008440 COILS Server 2026-09-12 01:00:58 169
Subread
 
Resource Report
Resource Website
1000+ mentions
Subread (RRID:SCR_009803) data processing software, software application, software resource Software package for high-performance read alignment, quantification and mutation discovery.General purpose read aligner which can be used to map both genomic DNA-seq reads and RNA-seq reads. Subread aligner as fast, accurate and scalable read mapping by seed-and-vote.These programs were also implemented in Bioconductor R package Rsubread. read alignment, DNA-seq reads mapping, RNA-seq reads mapping, mutation discovery, , bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Rsubread
has parent organization: University of Melbourne; Victoria; Australia
Australian Government ;
Australian National Health and Medical Research Council ;
Victorian State Government Operational Infrastructure Support
PMID:23558742 Free, Freely available OMICS_01255, biotools:subread https://bio.tools/subread, https://sources.debian.org/src/subread/ SCR_009803 2026-09-12 01:01:00 2138
GSA-SNP
 
Resource Report
Resource Website
10+ mentions
GSA-SNP (RRID:SCR_013109) GSA-SNP data processing software, software application, software resource A tool for the gene-set (or pathway) analysis of a genome-wide association study result. It accepts a genome-wide list of SNPs and their association P-values. It summarizes the SNP P-values into nearby genes. The gene-by-gene summary results are then further summarized by gene-sets such as Gene Ontology, KEGG pathways, or user-created gene-sets. Various standardization and statistical tests can be performed and the resulting gene-sets that pass a significance level after multiple-testing correction are reported. The tool is written in Java and is available as a standalone version. clinical neuroinformatics, computational neuroscience, imaging genomics, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
has parent organization: Soongsil University; Seoul; South Korea
PMID:20501604 GNU General Public License v2 nlx_155765, biotools:gsa-snp https://bio.tools/gsa-snp SCR_013109 2026-09-12 01:01:01 18
Trim Galore
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
Trim Galore (RRID:SCR_011847) Trim Galore! data processing software, software application, software resource Software tool to automate quality and adapter trimming as well as quality control, with some added functionality to remove biased methylation positions for RRBS sequence files for directional, non-directional or paired-end sequencing. Wrapper around Cutadapt and FastQC to consistently apply adapter and quality trimming to FastQ files, with extra functionality for Reduced Representation Bisulfite Sequencing data. Automate, quality, adapter, trimming, remove, biased, methylation, position, RRBS, reduced, representation, bisulfite, data, sequence, wrapper, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Babraham Institute
works with: cutadapt
Free, Available for download, Freely available biotools:trim_galore, OMICS_01096, SCR_016946 https://github.com/FelixKrueger/TrimGalore, https://bio.tools/trim_galore, https://sources.debian.org/src/trim-galore/ SCR_011847 TrimGalore 2026-09-12 01:01:00 7582
ToppCluster
 
Resource Report
Resource Website
100+ mentions
ToppCluster (RRID:SCR_001503) ToppCluster analysis service resource, data analysis service, production service resource, resource, service resource A tool for performing multi-cluster gene functional enrichment analyses on large scale data (microarray experiments with many time-points, cell-types, tissue-types, etc.). It facilitates co-analysis of multiple gene lists and yields as output a rich functional map showing the shared and list-specific functional features. The output can be visualized in tabular, heatmap or network formats using built-in options as well as third-party software. It uses the hypergeometric test to obtain functional enrichment achieved via the gene list enrichment analysis option available in ToppGene. term enrichment, gene, analysis, gene enrichment analysis, connectivity, heatmap, ortholog, microarray, function, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: GenitoUrinary Development Molecular Anatomy Project
is related to: ToppGene Suite
NIDDK 1U01DK70219;
NIDDK P30DK078392;
NCRR U54 RR025216;
NIDCR U01DE020049
PMID:20484371 Free OMICS_02225, nlx_152801, biotools:toppcluster https://bio.tools/toppcluster SCR_001503 ToppCluster: A multiple gene list feature analyzer for the dissection of biological systems 2026-09-12 01:00:07 152
StatAlign
 
Resource Report
Resource Website
1+ mentions
StatAlign (RRID:SCR_001892) data analysis software, data processing software, sequence analysis software, software application, software resource Software package for Bayesian analysis of protein, DNA and RNA sequences. It utilizes multiple alignments, phylogenetic trees and evolutionary parameters to quantify uncertainty in these analyses. It is written in Java. software package, bayesian, protein, dna, rna, sequencing, java, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
PMID:23335014 Free, Available for download, Freely available biotools:StatAlign, OMICS_03743 https://bio.tools/StatAlign SCR_001892 StatAlign 2.0 2026-09-12 01:00:07 1
FACTA+.
 
Resource Report
Resource Website
1+ mentions
FACTA+. (RRID:SCR_001767) FACTA+ data access protocol, service resource, software resource, web service Text mining tool to discover associations between biomedical concepts from MEDLINE articles. Use the service from your browser or via a Web Service. The whole MEDLINE corpus containing more than 20 million articles is indexed with an efficient text search engine, and it allows you to navigate such associations and their textual evidence in a highly interactive manner - the system accepts arbitrary query terms and displays relevant concepts immediately. A broad range of important biomedical concepts are covered by the combination of a machine learning-based term recognizer and large-scale dictionaries for genes, proteins, diseases, and chemical compounds. There is also a FACTA+ visualization service that can be found here: http://www.nactem.ac.uk/facta-visualizer/ text mining, gene, protein, disease, symptom, drug, enzyme, compound, biomedical, association, machine learning, chemical, text-mining software, bio.tools is listed by: OMICtools
is listed by: FORCE11
is listed by: bio.tools
is listed by: Debian
is related to: MEDLINE
has parent organization: National Centre for Text Mining
JISC PMID:18772154 Free, Freely available biotools:facta_plus, nif-0000-10272, OMICS_01181 http://refine1-nactem.mc.man.ac.uk/facta/, https://bio.tools/facta_plus SCR_001767 Finding Associated Concepts with Text Analysis 2026-09-12 01:00:07 2
FusionCatcher
 
Resource Report
Resource Website
1+ mentions
FusionCatcher (RRID:SCR_000060) data analysis software, data processing software, sequence analysis software, software application, software resource Software that searches for novel/known fusion genes, translocations, and chimeras in RNA-seq data (paired-end reads from Illumina NGS platforms like Solexa and HiSeq) from diseased samples. fusion gene, known fusion gene, translocation, chimera, rna-seq data, hiseq, solexa, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.1101/011650 Free, Available for download, Freely available biotools:fusioncatcher, OMICS_01348 https://github.com/ndaniel/fusioncatcher/blob/master/doc/manual.md, https://bio.tools/fusioncatcher http://code.google.com/p/fusioncatcher/ SCR_000060 2026-09-12 01:00:06 9
Dissect
 
Resource Report
Resource Website
Dissect (RRID:SCR_000058) Dissect alignment software, data processing software, image analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software transcriptome-to-genome alignment tool, which can identify and characterize transcriptomic events such as duplications, inversions, rearrangements and fusions. Structural events containing transcripts, transcriptome-to-genome alignment, identify and characterize transcriptomic events, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Simon Fraser University; British Columbia; Canada
PMID:22689759 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01346, biotools:dissect https://bio.tools/dissect SCR_000058 Dissect: DIScovery of Structural Events Containing Transcripts, DIScovery of Structural Events Containing Transcripts 2026-09-12 01:00:06 0
cpnDB: A Chaperonin Database
 
Resource Report
Resource Website
1+ mentions
cpnDB: A Chaperonin Database (RRID:SCR_002263) cpnDB analysis service resource, data analysis service, data or information resource, database, production service resource, service resource A curated collection of chaperonin sequence data collected from public databases or generated by a network of collaborators exploiting the cpn60 target in clinical, phylogenetic and microbial ecology studies. The database contains all available sequences for both group I and group II chaperonins. Users can search the database by Chaperonin type, group (I or II), BLAST, or other options, and can also enter and analyze FASTA sequences. chaperonin sequence, microbial ecology, phylogenetics, chaperonin, plastid, mitochondria, cytoplasm, sequence, blast, fasta, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
Canadian Biotechnology Strategy ;
National Research Council Genomics and Health Initiative
PMID:15289485 Free, Freely available biotools:cpndb, OMICS_01511, nif-0000-02694 https://bio.tools/cpndb http://www.cpndb.ca/cpnDB/home.php SCR_002263 2026-09-12 01:00:08 4
Predictions for Entire Proteomes
 
Resource Report
Resource Website
500+ mentions
Predictions for Entire Proteomes (RRID:SCR_002803) data analysis software, data processing software, sequence analysis software, software application, software resource, web application Web application for sequence analysis and the prediction of protein structure and function. The user interface intakes protein sequences or alignments and returned multiple sequence alignments, motifs, and nuclear localization signals., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 15,2026. sequence analysis database, protein structure prediction, protein structure, protein function, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: Columbia University; New York; USA
BMBF PMID:24799431
DOI:10.1093/nar/gkh377
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00136, OMICS_07135, biotools:predictprotein https://bio.tools/predictprotein, https://sources.debian.org/src/predictprotein/ http://cubic.bioc.columbia.edu/pep/ SCR_002803 PredictProtein 2026-09-12 01:00:08 643
RegulonDB
 
Resource Report
Resource Website
100+ mentions
RegulonDB (RRID:SCR_003499) RegulonDB data or information resource, database Database on transcriptional regulation in Escherichia coli K-12 containing knowledge manually curated from original scientific publications, complemented with high throughput datasets and comprehensive computational predictions. Graphic and text-integrated environment with friendly navigation where regulatory information is always at hand. They provide integrated views to understand as well as organized knowledge in computable form. Users may submit data to make it publicly available. transcription, gene regulation, operon, bacteria, evolutionary conservation, regulatory phrase, transcriptional regulation, transcriptional regulatory network, bio.tools, FASEB list is listed by: OMICtools
is listed by: 3DVC
is listed by: bio.tools
is listed by: Debian
has parent organization: National Autonomous University of Mexico; Mexico City; Mexico
NIGMS GM071962;
NIGMS GM077678;
Consejo Nacional de Ciencia y Tecnologia 103686;
Consejo Nacional de Ciencia y Tecnologia 179997;
Programa de Apoyo a Proyectos de Investigacion e Innovacion Tecnologica IN210810;
Programa de Apoyo a Proyectos de Investigacion e Innovacion Tecnologica IN209312
PMID:23203884 OMICS_01868, nif-0000-03399, biotools:regulondb https://bio.tools/regulondb SCR_003499 2026-09-12 01:00:09 153

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