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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Scalpel
 
Resource Report
Resource Website
50+ mentions
Scalpel (RRID:SCR_012107) software resource A software package for detecting INDELs (INsertions and DELetions) mutations in a reference genome which has been sequenced with next-generation sequencing technology (e.g., Illumina). software package, c++, perl, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:25128977 biotools:scalpel, OMICS_05395 https://bio.tools/scalpel SCR_012107 2026-09-05 06:27:20 62
xMSanalyzer
 
Resource Report
Resource Website
50+ mentions
xMSanalyzer (RRID:SCR_012144) software resource A software package of utilities for data extraction, quality control assessment, detection of overlapping and unique metabolites in multiple datasets, and batch annotation of metabolites. xMSanalyzer comprises of utilities that can be classified into five main modules: 1) merging apLCMS or XCMS sample processing results from multiple sets of parameter settings, 2) evaluation of sample quality, feature consistency, and batch-effect, 3) feature matching, and 4) characterization of m/z using KEGG REST; 5) Batch-effect correction using ComBat. software package, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: SourceForge
PMID:23323971 GNU General Public License OMICS_06039 SCR_012144 2026-09-05 06:27:21 90
freesurfR
 
Resource Report
Resource Website
freesurfR (RRID:SCR_014110) data analysis software, data processing software, software application, software resource, software toolkit A software package which contains tools for doing group analysis of FreeSurfer surface data using the general linear model in R (lm). Results can be rendered in FreeSurfer freeview or AFNI SUMA. Plots for selected vertices can be rendered in R with ggplot2. data analysis software, software package, group analysis, freesurfer, surface data, r linear model uses: FreeSurfer
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
Available for download SCR_014110 2026-09-05 06:27:43 0
minc-toolkit
 
Resource Report
Resource Website
1+ mentions
minc-toolkit (RRID:SCR_014138) data processing software, image processing software, software application, software resource, software toolkit A set of MINC-based image processing tools packaged together. It includes MINC, N3, BICPL, EBKTS, ANIMAL, INSECT, BEaST, Register, Display, and xdisp. image processing, software package uses: minc-toolkit-testsuite
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: McGill University; Montreal; Canada
Available to the research community http://www.bic.mni.mcgill.ca/ServicesSoftware/ServicesSoftwareMincToolKit, https://github.com/BIC-MNI/minc-toolkit SCR_014138 MINC Tool Kit 2026-09-05 06:27:43 9
HAMMER: Deformable Registration
 
Resource Report
Resource Website
HAMMER: Deformable Registration (RRID:SCR_014118) data processing software, image processing software, software application, software resource A software package which performs high-dimensional warping of brain images. Standard voxel-based analysis can be applied to these tissue density maps, in order to examine regional volumetrics, effects of disease, or correlations with clinical measurements. image processing, software package, warp, brain image is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Available for download SCR_014118 2026-09-05 06:27:43 0
Olympus Cell Software
 
Resource Report
Resource Website
10+ mentions
Olympus Cell Software (RRID:SCR_014342) data acquisition software, data analysis software, data processing software, software application, software resource, software toolkit A collection of 7 individual software packages that all control the Olympus Imaging systems while also providing different individual features including (but not limited to): basic measurement functions, process automation, ratio analysis, and real time image acquisition. software package, data analysis, data acquisition, real time, automation is provided by: Olympus Exclusive distributor for Greece, Pay for product, Only for Olympus Imaging systems SCR_014342 2026-09-05 06:27:45 16
Mascot
 
Resource Report
Resource Website
5000+ mentions
Mascot (RRID:SCR_014322) data processing software, signal processing software, software application, software resource, standalone software A software package and server used to identify and characterize proteins from primary sequence databases using mass spectrometry data. Mascot integrates peptide mass fingerprinting, sequence querying, and MS/MS ion searching in order to search for proteins in databases like SwissProt, NCBInr, EMBL EST divisions, contaminants, and cRAP. If a license is purchased, users may: search data sets that exceed the 1200 spectrum limit of the free version; set up automated, high throughput work; add and edit proteins and quantification methods; and search a preferred collection of sequence databases. The software package works with instruments from AB Sciex, Agilent, Bruker, Jeol, Shimadzu, Thermo Scientific, and Waters. server, software package, mass spectrometry, protein, identify, characterize, bio.tools is used by: MSQuant
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: MascotScan
Free, Can be licensed for in-house use, Available for download biotools:MASCOT http://www.matrixscience.com/search_intro.html, https://bio.tools/MASCOT SCR_014322 Mascot Server 2026-09-05 06:27:45 7141
Hierarchical Attribute Matching Mechanism for Elastic Registration
 
Resource Report
Resource Website
50+ mentions
Hierarchical Attribute Matching Mechanism for Elastic Registration (RRID:SCR_001960) HAMMER data processing software, software application, software resource Software package that performs high-dimensional warping of brain images. Standard voxel-based analysis can be applied to these tissue density maps, in order to examine regional volumetrics, effects of disease, or correlations with clinical measurements. In order to make HAMMER as robust as possible to different acquisition protocols and conditions, they provide a distribution that assumes that images have been skull-stripped and segmented into gray matter, white matter, and ventricular CSF. We have other software tools that can perform these steps, including skull stripping, reorientation and reslicing, and segmentation tools. Importantly, they use 250 for WM, 150 for GM, 50 for Ventricles and 10 for CSF in the tissue-segmented brain images. Current modules used for group analysis: Labeling subject brain using a manually-labeled brain Model; Generating RAVENS map for each tissue (WM, GM, VN); Normalizing subject brain images magnetic resonance, software package, data processing, high dimensional warping is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Pennsylvania; Philadelphia; USA
PMID:12575879
PMID:12507441
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00310 http://www.nitrc.org/projects/hammerwml SCR_001960 HAMMER: Deformable Registration 2026-09-05 06:30:37 50
Brainvox
 
Resource Report
Resource Website
1+ mentions
Brainvox (RRID:SCR_009448) data processing software, image analysis software, software application, software resource An interactive 3D rendering and neuroanatomical analysis package developed for analyzing focal brain lesions and functional brain imaging data (Damasio and Frank, 1991; Frank, Damasio and Grabowski, 1997). magnetic resonance, neuroanatomical analysis, software package, 3d, interactive, brain is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: INCF Software Center
PMID:9038281 Available for download nlx_155592 SCR_009448 2026-09-05 06:30:45 1
BROCCOLI
 
Resource Report
Resource Website
10+ mentions
BROCCOLI (RRID:SCR_014093) data processing software, image analysis software, software application, software resource A software package written in OpenCL (Open Computing Language) that can be used for parallel analysis of fMRI data on a large variety of hardware configurations. If BROCCOLI is running on a GPU, it can perform non-linear spatial normalization to a 1 mm brain template in 4-6 s and run a second level permutation test with 10,000 permutations. software package, parallel analysis, fmri, non linear spatial normalization, brain is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free https://github.com/wanderine/BROCCOLI/ SCR_014093 2026-09-05 06:30:48 22
clValid
 
Resource Report
Resource Website
50+ mentions
clValid (RRID:SCR_014626) data analysis software, data processing software, software application, software resource An R package which contains functions for validating the results of a clustering analysis. data analysis software, r, software package, cluster, cluster analysis, validation, results validation is related to: CRAN https://cran.r-project.org/web/packages/clValid/clValid.pdf SCR_014626 clValid - Validation of Clustering Results, clValid: Validation of Clustering Results 2026-09-05 06:27:49 86
GROMACS
 
Resource Report
Resource Website
5000+ mentions
GROMACS (RRID:SCR_014565) simulation software, software application, software resource, software toolkit Software package created to perform molecular dynamics. Molecular dynamics package mainly designed for simulations of proteins, lipids, and nucleic acids. Can also be used for research on non-biological systems, such as polymers. simulation, molecular dynamics, software package, software toolkit, biochemical, molecule, protein, lipid, nucleic acid, bond interaction, bio.tools is used by: CHARMM-GUI
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
European Research Council ;
Nvidia ;
Stream Computing Performance Engineers ;
Swedish eScience Research Center ;
Swedish Foundation for International Cooperation in Research and Higher Education ;
Swedish Foundation for Strategic Research ;
Swedish National Infrastructure for Computing ;
Swedish Research Council
PMID:26620784
DOI:10.1016/0010-4655(95)00042-E
Free, Available for download biotools:gromacs, OMICS_05081 https://bio.tools/gromacs, https://sources.debian.org/src/gromacs/, https://github.com/gromacs/gromacs SCR_014565 Gromacs 2026-09-05 06:27:48 9367
Analysis and Annotation Tool (AAT) Package
 
Resource Report
Resource Website
1+ mentions
Analysis and Annotation Tool (AAT) Package (RRID:SCR_014658) data analysis software, data processing software, software application, software resource Genome tool for analyzing and annotating large genomic sequences containing introns. It includes a program for comparing the query sequence with a protein database and another for comparing the query with a cDNA database. The database search program identifies regions of the query sequence that are similar to a database sequence. Then the alignment program constructs an optimal alignment for each region and the database sequence, as well as reports the coordinates of exons in the query sequence. Pairwise alignments of the query sequence with protein and cDNA database sequences are combined into multiple sequence alignments, which provide a view of all protein and cDNA sequences matching a query region. data analysis, software package, genome tool, genomic sequences, query sequence, protein database, cdna database Available for download SCR_014658 Analysis and Annotation Tool Package, AAT Package 2026-09-05 06:27:49 1
LeadIT
 
Resource Report
Resource Website
100+ mentions
LeadIT (RRID:SCR_014881) software resource Drug discovery platform for medicinal and computational researchers. Users can assess the binding affinity and contributions to binding of a complex, find new scaffolds, grow molecules towards pharmacophore points, link fragments, and investigate possible dock binding conformations. drug discovery, platform, binding, docking, complex, small molecule, software package, drug design License must be purchased, Older versions are available SCR_014881 2026-09-05 06:27:51 151
MOE
 
Resource Report
Resource Website
10+ mentions
MOE (RRID:SCR_014882) software resource Drug discovery software package which can be used in structure-based design, fragment-based design, pharmacophore discovery, medicinal chemistry, protein and antibody modelling, and molecular modeling and simulations. Each aspect of the software package has its own unique features: for example, features for structure-based design include active site detection, scaffold replacement, multi fragment search, and solvent analysis. drug discovery, software package, structure based design, fragment based design, pharmacophore, medicinal chemistry, protein modeling, antibody modeling, molecular modeling, molecular simulations is listed by: SoftCite SCR_014882 2026-09-05 06:27:51 27
HKL 3000
 
Resource Report
Resource Website
100+ mentions
HKL 3000 (RRID:SCR_015023) data acquisition software, data processing software, software application, software resource Semi-automatic crystallographic data collection software that integrates data collection, data reduction, phasing and model building in a single software package. crystallography, crystallographic data collection, software package, hardware management software PMID:16855301 License required https://www.rigaku.com/en/products/protein/hkl3000r SCR_015023 HKL-3000, HLK3000, HKL 3000R, HKL-3000R, HKL3000R 2026-09-05 06:27:53 182
RUVSeq
 
Resource Report
Resource Website
100+ mentions
RUVSeq (RRID:SCR_006263) software resource Software package that implements the remove unwanted variation (RUV) methods for the normalization of RNA-Seq read counts between samples. software package, unix/linux, mac os x, windows, r, differential expression, preprocessing, rna-seq is listed by: OMICtools
has parent organization: Bioconductor
PMID:25150836 Artistic License, v2 OMICS_05652 SCR_006263 RUVSeq: Remove Unwanted Variation from RNA-Seq Data 2026-09-05 06:25:49 481
Prime
 
Resource Report
Resource Website
500+ mentions
Prime (RRID:SCR_014887) software application, software resource Software package that uses homology modeling and fold recognition to make protein structure predictions. software package, protein structure, protein strcuture prediction, homology modeling, fold recognition, drug design is listed by: SoftCite Commercial SCR_014887 2026-09-05 06:32:59 691
topGO
 
Resource Report
Resource Website
1000+ mentions
topGO (RRID:SCR_014798) software resource, software toolkit Software package which provides tools for testing GO terms while accounting for the topology of the GO graph. Different test statistics and different methods for eliminating local similarities and dependencies between GO terms can be implemented and applied. r, go, go graph, local similarities, software tool, software package, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
works with: Gene Ontology
is hosted by: Bioconductor
Available for download biotools:topgo https://bio.tools/topgo SCR_014798 2026-09-05 06:32:59 3080
ncdfFlow
 
Resource Report
Resource Website
ncdfFlow (RRID:SCR_000009) software resource Software package that provides netCDF storage based methods and functions for manipulation of flow cytometry data. software package, mac os x, unix/linux, windows, r, flow cytometry is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_05617 SCR_000009 ncdfFlow: A package that provides ncdf based storage for flow cytometry data 2026-09-07 08:55:13 0

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