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http://www.scienceexchange.com/facilities/aptagen

Supplier of aptamers, RNA or DNA that binds with high affinity and specificity to targets such as small organics, peptides, proteins, cells, and tissues. Unlike antibodies, some aptamers exhibit stereoselectivity. In addition, aptamers have been generated that exhibit greater than 10,000-fold binding affinity for theophylline over caffeine, which differ from one another in structure by only a single methyl group.

Proper citation: Aptagen (RRID:SCR_012607) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/university-of-north-carolina-at-chapel-hill

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. Portal, Core facility.

Proper citation: University of North Carolina at Chapel Hill Labs and Facilities (RRID:SCR_012447) Copy   

•   Source: SciCrunch Registry

https://biotium.com/

An Antibody supplier

Proper citation: Biotium inc (RRID:SCR_013538) Copy   

•   Source: SciCrunch Registry

http://search.cpan.org/dist/Bio-ToolBox/lib/Bio/ToolBox.pm

Tools for querying and analysis of genomic data. These libraries provide a useful interface for working with bioinformatic data. Many bioinformatic data analysis revolves around working with tables of information, including lists of genomic annotation (genes, promoters, etc.) or defined regions of interest (epigenetic enrichment, transcription factor binding sites, etc.). This library works with these tables and provides a set of common tools for working with them. Opening and saving common tab-delimited text formats Support for BED, GFF, VCF, narrowPeak files Scoring intervals with datasets from microarray and sequencing ChIPSeq, RNASeq, microarray expression Support for Bam, BigWig, BigBed, wig, and USeq data formats Intersection with other known annotation Works with any genomic annotation in GTF, GFF3, and UCSC formats The libraries provide a unified and integrated approach to analyses. In many cases, they provide an abstraction layer over a variety of different specialized BioPerl and related modules. Instead of writing numerous scripts specialized for each data format (wig, bigWig, Bam), one script can now work with any data format.

Proper citation: BioToolBox (RRID:SCR_015696) Copy   

•   Source: SciCrunch Registry

http://www.aniseed.cnrs.fr/

Database of ascidian embryonic development at the level of the genome (cis-regulatory sequences, gene expression, protein annotation), of the cell (morphology, fate, induction, lineage) or of the whole embryo (anatomy, morphogenesis). Currently, four organism models are described in Aniseed: Ciona intestinalis, Ciona savignyi, Halocynthia roretzi and Phallusia mammillata.
This version supports four sets of Ciona intestinalis transcript models: JGI v1.0, KyotoGrail 2005, KH and ENSEMBL, all functionally annotated, and grouped into Aniseedv3.0 gene models. Users can explore their expression profiles during normal or manipulated development, access validated cis-regulatory regions, get the molecular tools used to assay gene function, or all articles related to the function, or regulation of a given gene. Known transcriptional regulators and targets are listed for each gene, as are the gene regulatory networks acting in individual anatomical territories.
ANISEED is a community tool, and the direct involvement of external contributors is important to optimize the quality of the submitted data. Virtual embryo: The 3D Virtual embryo is available to download in the download section of the website.

Proper citation: Ascidian Network for InSitu Expression and Embryological Data (RRID:SCR_013030) Copy   

•   Source: SciCrunch Registry

http://www.topqbiosystems.com

Contract research organization that performs IHC detection of antigens in tissue and cell samples. Some target antigens are difficult-to-detect because of various reasons. We offer the following quality IHC services with the primary antibodies provided by customers: -Primary antibody selections -Formalin fixed paraffin embedded (FFPE) tissue sample sectioning -Processing condition optimizations -IHC single or double staining (colorimetric or fluorescent) FFPE slides TMA slides -IHC data analysis

Proper citation: TopQ BioSystems (RRID:SCR_012424) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/enzymatics

Enzymatics is an independent, ISO 13485:2003 certified OEM manufacturer of enzymes that brings to the marketplace a unique, quality oriented, and customer focused approach to protein production. The company was founded in 2006 to specifically address the needs of commercial entities engaged in the development, manufacture, and distribution of platforms dedicated to nucleic acid identification. Enzymes are critical to the performance of these applications and the industry''s relentless pursuit of higher performance emphasizes the need for analytical reagent purity and absolute production consistency. Operating from the perspective that we are a manufacturing division of our customer, Enzymatics consistently delivers the highest quality and value enzymes, leveraging them to drive customer success via a partnership business model; and our tremendous success confirms the need in the marketplace for a dedicated partner in the realm of enzyme technologies.

Proper citation: Enzymatics (RRID:SCR_012545) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/caresbio-laboratory

CaresBio Laboratory (CBL) is a contract research organization, serving as a translational link with the one stop service approach to close the gaps between basic and clinical sciences for biomedical science community. We are serving academic laboratories, CROs, biotechnology and pharmaceutical companies and research organizations by providing high quality and cost effective pre-clinical and clinical research services. If you are doing biomarker and or drug discovery and development; therapeutics and translational research along with the applications of genomics and proteomics study; data validation and analysis; histopathology, immunohistochemistry, pathology or other immunostaining, imaging; histomorphometry, image analysis; small animal imaging; screening, efficacy and toxicity testing of your candidate compounds. We also provide biostatistics analysis of pre-clinical and or clinical data, data base developments or any subcategories of these fields. We do assay developments and provide customized assays to match your needs.

Proper citation: CaresBio Laboratory (RRID:SCR_012393) Copy   

•   Source: SciCrunch Registry

http://www.diabetes-translation.org

Centers that are part of an integrated program whose cores support and enhance diabetes type II translation research. The CDTRs aim to enhance the efficiency, productivity, effectiveness and multidisciplinary nature of diabetes translation research.

Proper citation: Centers for Diabetes Translation Research (RRID:SCR_015149) Copy   

•   Source: SciCrunch Registry

http://www.sph.umich.edu/csg/abecasis/QTDT/

How is association mapping going to help me find genes? During the past decade, the genes for a large number of rare mendelian traits have been identified. However, traditional linkage analyses lack power and precision when applied to complex disease. Association mapping, which compares the effects of different chromosomal variants, may be more successful at identifying genes of small effect. How does QTDT help association mapping? Association mapping can produce misleading results when the study population is not homogeneous, but includes individuals with different genetic backgrounds. Family based association tests, commonly referred to as TDTs (Transmission Disequilibrium Tests), do not produce misleading results in these circumstances. QTDT can use all the information in a pedigree to construct powerful tests of association that are robust in the presence of stratification. What does the Q stant for ? Q stands for Quantitative. Quantitative traits provide effective descriptions of many complex diseases, including asthma. For many of these conditions, all or nothing definitions of disease are arbitrary and unsatisfactory. QTDT incorporates variance components methodology in the analysis of family data and includes exact estimation of p-values for analysis of small samples and non-normal data. The QTDT abbreviation (for Quantitative Transmission Disequilibrium Tests) was first used by David Allison in his 1997 paper. This research was supported in part by the intramural program of the National Eye Institute and by National Institutes of Health Grants EY016862, EY007758, EY09859, EY012118, P30-EY014801, EY-014458, EY014467, HL084729, and HG002651, by the Foundation Fighting Blindness, the Macula Vision Research Foundation, the American Health Assistance Foundation, Research to Prevent Blindness, the Pew Charitable Trusts, the Mayo Clinic Foundation, the Casey Macular Degeneration Center Fund, the Marion W. and Edward F. Knight AMD Fund, the Harold and Pauline Price Foundation, National Genotyping Centre of Spain, and the Elmer and Sylvia Sramek Foundation. The Center for Inherited Disease Research, fully funded through a federal contract (HHSN268200782096C) from National Institutes of Health to

Proper citation: Linkage Disequilibrium Analyses for Quantitative and Discrete Traits (RRID:SCR_013365) Copy   

•   Source: SciCrunch Registry

https://www.idigbio.org

iDigBio is the National Resource for Advancing Digitization of Biodiversity Collections (ADBC) funded by the National Science Foundation. Through ADBC, data and images for millions of biological specimens are being made available in electronic format for the research community, government agencies, students, educators, and the general public.

Proper citation: Integrated Digitized Biocollections (RRID:SCR_014336) Copy   

•   Source: SciCrunch Registry

https://www.thermofisher.com/order/catalog/product/4475073

Genotyping software package that provides DNA sizing and quality allele calls for all Applied Biosystems electrophoresis-based genotyping systems. GeneMapper specializes in multiapplication functionality, including amplified fragment length polymorphism, loss of heterozygosity, microsatellite, and SNP genotyping analysis. The software provides remote auto-analysis and command line operation, and allows for multiuser, client-server deployment.

Proper citation: GeneMapper (RRID:SCR_014290) Copy   

•   Source: SciCrunch Registry

http://psych.colorado.edu/~lharvey/html/software.html

Software that fits s-shaped psychometric functions to psychophysical data using a maximum-likelihood technique. The psychometric functions available are logistic, Weibull, Gaussian integral, cumulative Poisson and step. PsychoFit produces, among other things, files with graphic information suitable for importing in a graphic program for plotting., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: PsychoFit (RRID:SCR_015381) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/barts-and-the-london-school-of-medicine-and-dentistry

Barts and The London offers international levels of excellence in research and teaching while serving a population of unrivalled diversity. Through partnership with our linked trusts, notably Barts and The London NHS Trust, and our associated University Hospital Trusts _������������_ Homerton, Newham, Whipps Cross and Queen''''s (Romford) the School''''s research and teaching is informed by an exceptionally wide ranging and stimulating clinical environment.

Proper citation: Barts and The London School of Medicine and Dentistry Labs and Facilities (RRID:SCR_012710) Copy   

•   Source: SciCrunch Registry

http://globalprojects.ucsf.edu/project/novel-small-molecule-therapies-cystic-fibrosis

Research center that focuses on developing novel therapies for cystic fibrosis, enhancing research projects examining the mechanisms of the disease, and developing new small-molecule therapies that can be translated into the clinic.

Proper citation: Cystic Fibrosis Center - University of California San Francisco (RRID:SCR_015398) Copy   

•   Source: SciCrunch Registry

http://www.mybiosource.com/

An Antibody supplier

Proper citation: MyBioSource (RRID:SCR_013493) Copy   

•   Source: SciCrunch Registry

http://www.vislab.ucl.ac.uk/cogent_2000.php

MATLAB Toolbox for presenting stimuli and recording responses with precise timing. It also provides additional utilities for the manipulation of sound, keyboard, mouse, joystick, serial port, parallel port, subject responses and physiological monitoring hardware.

Proper citation: Cogent 2000 (RRID:SCR_015672) Copy   

•   Source: SciCrunch Registry

http://healthybrain.umn.edu/

Research forum portal to address brain status by acquiring comprehensive, multimodal data from healthy humans across the lifespan to characterize brain status, assess its change over time, and associate composite descriptors of brain status. Specifically, the measurements are acquired noninvasively by existing neuroimaging technologies (structural MRI, functional MRI, magnetic resonance spectroscopy, diffusion MRI, and magnetoencephalography); in addition, genetic, cognitive, language, and lifestyle data are acquired. Goals: * Derive the Brain Health Index- An integrative assessment of brain status derived from multimodal measurements of brain structure, function, and chemistry. * Continue acquiring data to construct the first-ever databank on brain, cognitive, language and genetic measurements for healthy people across the lifespan. * Provide a novel and unique dataset by which to: characterize brain status, assess its change over time, and associate it with genetic makeup, cognitive function, and language abilities. * Forecast future brain health and disease based on current measurements and guide physicians towards new interventions and evaluate interventions as they develop. * Extend to siblings and other family members to further assess the genetic influences and inheritability.

Proper citation: HBP: Healthy Brain Project (RRID:SCR_013137) Copy   

•   Source: SciCrunch Registry

http://crn2m.univ-mrs.fr/pub/recherche/equipe-t-brue/jullien-nicolas/programmation/amplifx/?lang=fr

A software for managing, testing, and drawing primers. The software can locate primers for target sequences, calculate the quality score, predict amplified fragments and dimers, and create graphic representations of the primers.

Proper citation: AmplifX (RRID:SCR_014465) Copy   

•   Source: SciCrunch Registry

http://www.cytoskeleton.com/antibodies

An Antibody supplier

Proper citation: Cytoskeleton (RRID:SCR_013532) Copy   

•   Source: SciCrunch Registry