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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Scrattch.Hicat
 
Resource Report
Resource Website
10+ mentions
Scrattch.Hicat (RRID:SCR_018099) data analytics software, software application, software resource Software R package as hierarchical, iterative clustering for analysis of transcriptomics data.Used for single cell RNA-seq analysis for transcriptomic type characterization from Allen Institute. Hierarchical, iterative clustering, analysis, transcriptomics, data, single cell RNAseq, Allen Institute has parent organization: Allen Institute Free, Available for download, Freely available SCR_018099 Scrattch Hierarchical, Iterative Clustering for Analysis of Transcriptomics 2026-09-12 01:02:55 32
QGIS
 
Resource Report
Resource Website
100+ mentions
QGIS (RRID:SCR_018507) software application, software resource Open source cross platform desktop geographic information system application that supports viewing, editing, and analysis of geospatial data. Functions as geographic information system software, allowing users to analyze and edit spatial information, in addition to composing and exporting graphical maps. Geographic information system, viewing, editing, analysis, geospatial data, spatial information analysis, graphical map, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:QGIS https://bio.tools/QGIS SCR_018507 2026-09-12 01:02:56 488
GeneMerge
 
Resource Report
Resource Website
10+ mentions
GeneMerge (RRID:SCR_005744) GeneMerge analysis service resource, data analysis service, production service resource, service resource, software application, software resource THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. Web-based and standalone application that returns a wide range of functional genomic data for a given set of study genes and provides rank scores for over-representation of particular functions or categories in the data. It uses the hypergeometric test statistic which returns statistically correct results for samples of all sizes and is the #2 fastest GO tool available (Khatri and Draghici, 2005). GeneMerge can be used with any discrete, locus-based annotation data, including, literature references, genetic interactions, mutant phenotypes as well as traditional Gene Ontology queries. GeneMerge is particularly useful for the analysis of microarray data and other large biological datasets. The big advantage of GeneMerge over other similar programs is that you are not limited to analyzing your data from the perspective of a pre-packaged set of gene-association data. You can download or create gene-association files to analyze your data from an unlimited number of perspectives. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene, genomics, functional genomic data, analysis, post-genomic analysis, data mining, hypothesis testing, statistical analysis, slimmer-type tool, term enrichment, text mining, false discovery rate, bonferroni correction, false discovery rate and bonferroni correction, perl, microarray is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Harvard University; Cambridge; United States
PMID:12724301 THIS RESOURCE IS NO LONGER IN SERVICE nlx_149203 http://genemerge.cbcb.umd.edu/ SCR_005744 2026-09-12 01:00:11 26
Synapse
 
Resource Report
Resource Website
1000+ mentions
Synapse (RRID:SCR_006307) Synapse data or information resource, data repository, database, service resource, storage service resource A cloud-based collaborative platform which co-locates data, code, and computing resources for analyzing genome-scale data and seamlessly integrates these services allowing scientists to share and analyze data together. Synapse consists of a web portal integrated with the R/Bioconductor statistical package and will be integrated with additional tools. The web portal is organized around the concept of a Project which is an environment where you can interact, share data, and analysis methods with a specific group of users or broadly across open collaborations. Projects provide an organizational structure to interact with data, code and analyses, and to track data provenance. A project can be created by anyone with a Synapse account and can be shared among all Synapse users or restricted to a specific team. Public data projects include the Synapse Commons Repository (SCR) (syn150935) and the metaGenomics project (syn275039). The SCR provides access to raw data and phenotypic information for publicly available genomic data sets, such as GEO and TCGA. The metaGenomics project provides standardized preprocessed data and precomputed analysis of the public SCR data. data sharing, collaboration, data management, analysis, genome, phenotype, crowd sourcing, open data, provenance, resource management, annotation, authoring, markup, r, python, java, command-line, cloud, FASEB list is used by: NF Data Portal
is listed by: FORCE11
is listed by: DataCite
is listed by: re3data.org
is related to: clearScience
is related to: Exemplar Microscopy Images of Tissues
has parent organization: Sage Bionetworks
Cancer, Normal, Cardiovascular disease, Floppy hat syndrome Life Sciences Discovery Fund ;
NCI ;
NHLBI ;
Alfred P. Sloan Foundation
The community can contribute to this resource nlx_151983, DOI:10.17616/R3B934, r3d100011894, DOI:10.7303 https://doi.org/10.17616/R3B934, https://doi.org/10.48550/arxiv.1506.00272, https://doi.org/10.7303/, https://dx.doi.org/10.7303, https://doi.org/10.17616/R3B934 SCR_006307 2026-09-12 01:00:12 1104
Clair library
 
Resource Report
Resource Website
Clair library (RRID:SCR_007019) Clairlib data analysis software, data processing software, software application, software resource, software toolkit, text extraction software, text-mining software A suite of open-source Perl modules intended to simplify a number of generic tasks in natural language processing (NLP), information retrieval (IR), and network analysis (NA). Its architecture also allows for external software to be plugged in with very little effort. The latest version of clairlib is 1.06 which was released on March 2009 and includes about 130 modules implementing a wide range of functionalities. Clairlib is distributed in two forms: * Clairlib-core, which has essential functionality and minimal dependence on external software, and * Clairlib-ext, which has extended functionality that may be of interest to a smaller audience. Much can be done using Clairlib on its own. Some of the things that Clairlib can do are: Tokenization, Summarization, Document Clustering, Document Indexing, Web Graph Analysis, Network Generation, Power Law Distribution Analysis, Network Analysis, RandomWalks on Graphs, Tf-IDF, Perceptron Learning and Classification, and Phrase Based Retrieval and Fuzzy OR Queries. analysis, information, linguistic, module, network, process, retrieval, perl, natural language processing, information retrieval, network analysis is listed by: Biositemaps
has parent organization: University of Michigan; Ann Arbor; USA
NSF IIS 0534323;
NSF IIS 0329043;
NSF BCS 0527513;
NLM R01 LM008106;
NIDA U54 DA021519
Open unspecified license: Content is available under GNU Free Documentation License 1.3 or later. nif-0000-33210 SCR_007019 Computational Linguistics And Information Retrieval Library 2026-09-12 01:00:12 0
GIMME
 
Resource Report
Resource Website
1+ mentions
GIMME (RRID:SCR_014115) GIMME data analysis software, data processing software, software application, software resource, software toolkit Software Matlab toolbox for directed functional connectivity analysis of fMRI BOLD signal from predefined regions of interest. It recovers true structure of connections and estimates weights attributed to each connection. Obtains patterns at group and individual levels. Functional, connectivity, analysis, fMRI, BOLD, signal, predefined, region, pattern, BRAIN Initiative uses: MATLAB
is recommended by: BRAIN Initiative
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Pennsylvania; Philadelphia; USA
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
NIBIB EB022904;
NIBIB R21 EB015573;
NSF 0852147
PMID:22732562 Free, Available for download, Freely available SCR_014115 Group Iterative Multiple Model Estimation 2026-09-12 01:00:16 2
DESeq2
 
Resource Report
Resource Website
10000+ mentions
DESeq2 (RRID:SCR_015687) data analysis software, data processing software, software application, software resource, software tool Software package for differential gene expression analysis based on the negative binomial distribution. Used for analyzing RNA-seq data for differential analysis of count data, using shrinkage estimation for dispersions and fold changes to improve stability and interpretability of estimates. differential, gene, expression, analysis, binominal, distribution, RNA-seq data, Bioconductor, bio.tools is used by: Glimma
is used by: TEtranscripts
is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: SARTools
works with: tximport
European Union’s 7th Framework Programme ;
International Max Planck Research School for Computational Biology and Scientific Computing ;
NCI T32 CA009337
Free, Available for download, Freely available biotools:deseq2 https://github.com/mikelove/DESeq2, https://bio.tools/deseq2 SCR_015687 2026-09-12 01:00:17 50789
Pipeline Pilot
 
Resource Report
Resource Website
100+ mentions
Pipeline Pilot (RRID:SCR_014917) data analysis software, data processing software, software application, software resource Software used to automate the process of accessing, analyzing and reporting scientific data. This software can be used by a person with little or no software development experience can create scientific protocols that can be executed through a variety of interfaces including: BIOVIA Web Port, other BIOVIA solutions such as BIOVIA Electronic Lab Notebook, Isentris, Chemical Registration and third-party applications such as Microsoft SharePoint. The protocols aggregate and provide immediate access to volumes of research data, they automate the scientific analysis of data and allow researchers to explore, visualize and report results. automation, accessing, analysis, analyzing, scientific data, aggregation. aggregate, research, scientific is listed by: SoftCite Commercial SCR_014917 2026-09-12 01:00:17 358
Pilon
 
Resource Report
Resource Website
1000+ mentions
Pilon (RRID:SCR_014731) data analysis software, data processing software, sequence analysis software, software application, software resource Software tool to automatically improve draft assemblies and find variation among strains, including large event detection. FASTA files of genome along with one or more BAM files of reads aligned as input. Read alignment analysis is used to identify inconsistencies between input genome and evidence in reads, then attempts to make improvements to genome. automatically, improve, draft, assembly, variation, strain, genome, read, alignment, analysis, inconsistency, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is related to: shovill
is hosted by: GitHub
DOI:10.1371/journal.pone.0112963
DOI:10.1371/journal.pone.0112963
Available for download, Acknowledgement requested OMICS_14553, biotools:pilon https://github.com/broadinstitute/pilon/wiki, https://bio.tools/pilon, https://sources.debian.org/src/pilon/ SCR_014731 2026-09-12 01:00:17 3377
Brain Imaging Analysis Kit
 
Resource Report
Resource Website
10+ mentions
Brain Imaging Analysis Kit (RRID:SCR_014824) BrainIAK data processing software, image analysis software, software application, software resource, software toolkit Open source software package of Python modules for neuroscience, primarily focused on functional Magnetic Resonance Imaging (fMRI) analysis. Used for analyzing neuroimaging data. brain, python, module, imaging, fmri, data, analysis, neuroimaging is related to: Intel
has parent organization: Princeton University; New Jersey; USA
Free, Available for download, Freely available https://github.com/brainiak/brainiak SCR_014824 BrainIAK, Brain Imaging Analysis Kit, Brain Imaging Analysis Kit (BrainIAK) 2026-09-12 01:00:17 30
Roary
 
Resource Report
Resource Website
500+ mentions
Roary (RRID:SCR_018172) data analysis software, data processing software, sequence analysis software, software application, software resource Software tool for rapid large scale prokaryote pan genome analysis. Builds large scale pan genomes, identifying core and accessory genes. Makes construction of pan genome of thousands of prokaryote samples on standard desktop without compromising on accuracy of results. Not intended for meta genomics or for comparing extremely diverse sets of genomes. Genome analysis, prokaryote pan genome, pan genome, gene identification, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
works with: Scoary
Wellcome Trust PMID:26198102 Free, Available for download, Freely available OMICS_09491, biotools:roary https://github.com/sanger-pathogens/Roary, https://bio.tools/roary, https://sources.debian.org/src/roary/ SCR_018172 2026-09-12 01:00:20 710
StringTie
 
Resource Report
Resource Website
1000+ mentions
StringTie (RRID:SCR_016323) data analysis software, data processing software, sequence analysis software, software application, software resource Software application for assembling of RNA-Seq alignments into potential transcripts. It enables improved reconstruction of a transcriptome from RNA-seq reads. This transcript assembling and quantification program is implemented in C++ . assembling, RNA, sequence, transcript, gene, alignment, reconstruction, read, analysis, process, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
NCI R01 CA120185;
NCI R01 CA134292;
NHGRI R01 HG006102;
NHGRI R01 HG006677;
NIGMS R01 GM105705;
the Cancer Prevention and Research Institute of Texas
PMID:25690850
DOI:10.1038/nbt.3122
Open source, Free, Freely available, Available for download biotools:stringtie, OMICS_07226 https://github.com/gpertea/stringtie, https://bio.tools/stringtie, https://sources.debian.org/src/stringtie/ SCR_016323 2026-09-12 01:00:18 4976
MrDiffusion
 
Resource Report
Resource Website
1+ mentions
MrDiffusion (RRID:SCR_016567) data analysis software, data processing software, data visualization software, image analysis software, software application, software resource Software package for diffusion imaging analysis and visualization. Module of Vistasoft for processing diffusion weighted data and measuring and visualizing fractional anisotropy, mean diffusivity, axial and radial diffusivity, RGB fiber direction maps and analysis of MRI data., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. diffusion, imaging, analysis, visualization, data, fractional, anisotropy, MRI is related to: MATLAB
has parent organization: Stanford University; Stanford; California
THIS RESOURCE IS NO LONGER IN SERVICE https://github.com/vistalab/vistasoft/tree/master/mrDiffusion SCR_016567 2026-09-12 01:00:19 9
Spyder
 
Resource Report
Resource Website
50+ mentions
Spyder (RRID:SCR_017585) software application, software development environment, software development tool, software resource Interactive scientific development environment package for Python. Used for editing, analysis, debugging, and profiling functionality of comprehensive development tool with data exploration, interactive execution, deep inspection, and visualization. Python, environment, editing, analysis, debugging, profiling, functionality, development, data, exploration, visualization is related to: Pythonxy Free, Available for download, Freely available SCR_017585 2026-09-12 01:00:20 75
UMMPerfusion
 
Resource Report
Resource Website
1+ mentions
UMMPerfusion (RRID:SCR_015970) data processing software, image analysis software, software application, software resource, software toolkit Analysis software for dynamic contrast enhanced magnetic resonance images with implementation of a pixel-by-pixel deconvolution approach. It quantifies T1-weighted contrast-enhanced dynamic MR imaging (DCE-MRI) perfusion data as an OsiriX plug-in. DCE-MRI, t1, weighted, imaging, mr, magnetic, resonance, analysis, digital, perfusion, parameter, data, set, image, algorithm, contrast, pixel is affiliated with: Heidelberg University; Baden-Wurttemberg; Germany Heinrich-Vetter-Stiftung PMID:22832894 Open source, Available for download, Runs on Mac OS, Tutorial available SCR_015970 OsiriX plugin 2026-09-12 01:00:18 6
FreeContact
 
Resource Report
Resource Website
10+ mentions
FreeContact (RRID:SCR_016113) alignment software, data processing software, image analysis software, software application, software resource Alignment software for large-scale protein contact or protein-protein interaction prediction optimized for speed through shorter runtimes. FreeContact provides the opportunity to compute contact predictions in any environment (desktop or cloud). protein, structure, prediction, sequence, analysis, fast, contact, alignment, multiple is listed by: OMICtools
is related to: Debian
Alexander von Humboldt Foundation ;
German Ministry for Research and Education (BMBF: Bundesministerium fuer Bildung und Forschung) ;
Research Council of Norway 208481
PMID:24669753
DOI:10.1186/1471-2105-15-85
Open source, Free, Available for download OMICS_03520 https://rostlab.org/owiki/index.php/FreeContact, https://sources.debian.org/src/libfreecontact-perl/ SCR_016113 2026-09-12 01:00:18 22
QModeling
 
Resource Report
Resource Website
1+ mentions
QModeling (RRID:SCR_016358) data analysis software, data processing software, image analysis software, software application, software resource, software toolkit Software toolbox for Statistical Parametric Mapping (SPM) to fit reference-region kinetic models (SRTM, SRTM2, Patlak Reference and Logan Reference Plot) are currently available in QModeling to dynamic PET studies. Used for the analysis of brain imaging data sequences. statistical, parametric, mapping, reference, region, kinetic, model, dynamic, analysis, brain, data, imaging, sequence is related to: University of Malaga; Andalusia; Spain
is related to: MATLAB
DOI:10.1007/s12021-018-9384-y Free, Available for download, Available after registration SCR_016358 2026-09-12 01:00:18 1
SCDE
 
Resource Report
Resource Website
10+ mentions
SCDE (RRID:SCR_015952) data analysis software, data processing software, sequence analysis software, software application, software resource Software package that implements a set of statistical methods for analyzing single-cell RNA-seq data, including differential expression analysis (Kharchenko et al.) and pathway and geneset overdispersion analysis (Fan et al.) statistic, single, cell, rna, seq, rnaseq, differential, analysis, pathway, gene, geneset, dispersion, overdispersion, bayesian, expression, magnitude Leukemia and Lymphoma Research UK ;
Leukemia and Lymphoma Society ;
NHLBI R01 HL097794;
NIA K25 AG037596;
NIDDK R01 DK050234
PMID:24836921 Free, Available for download SCR_015952 2026-09-12 01:00:18 32
geomorph
 
Resource Report
Resource Website
10+ mentions
geomorph (RRID:SCR_016482) geomorph data analysis software, data processing software, software application, software resource, software toolkit Software package for performing all stages of geometric morphometric shape analysis of landmark points and curves in 2-and-3-dimensions as well as 3D surfaces in the R statistical computing environment. geometric, morphometric, shape, analysis, landmark, point, curve, 2D, 3D, surface is listed by: CRAN
is related to: R Project for Statistical Computing
Free, Available for download, Freely available https://github.com/geomorphR/geomorph SCR_016482 geometric morphometric 2026-09-12 01:00:19 35
NanoPipe
 
Resource Report
Resource Website
1+ mentions
NanoPipe (RRID:SCR_016852) NanoPipe analysis service resource, data access protocol, data analysis service, production service resource, service resource, software resource, web service Web tool for analysis of MinION (ONT) long sequencing reads. Used for analysis of reads generated by the Oxford Nanopore sequencing devices. Provides alignments to any target of interest, alignment statistics and information about polymorphisms. analysis, MinION, long, sequence, read, Oxford Nanopore, alignment, target, statistics, polymorphism, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Muenster; Muenster; Germany
Institute of Bioinformatics Muenster ;
Germany
PMID:30689855 Free, Available for download, Freely Available biotools:NanoPipe https://github.com/IOB-Muenster/nanopipe2, https://bio.tools/NanoPipe SCR_016852 NanoPipe, nanopipe2 2026-09-12 01:00:19 5

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