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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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MultiNet Resource Report Resource Website 10+ mentions |
MultiNet (RRID:SCR_016149) | software resource | Software for an integrated network combining multiple biological network database sources into a single human protein interactome. The software package contains gene interaction pairs corresponding to the unified global network. | network, integration, human, protein, interactome, gene, interaction | PMID:23505346 | Free, Available for download | SCR_016149 | 2026-09-05 06:28:04 | 14 | ||||||||||
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Human Islet Research Network (HIRN) Resource Report Resource Website 100+ mentions |
Human Islet Research Network (HIRN) (RRID:SCR_014393) | HIRN | data or information resource, disease-related portal, portal, topical portal | Network helps to organize and support collaborative research related to loss of functional beta cell mass in Type 1 Diabetes (T1D). Project consists of four independent research initiatives: Consortium on Beta Cell Death and Survival (CBDS), Consortium on Human Islet Biomimetics (CHIB), Consortium on Modeling Autoimmune Interactions (CMAI), Consortium on Targeting and Regeneration (CTAR), and Human Pancreas Analysis Program (HPAP). | islet, human, consortia, functional loss, beta cell, research network, funding resource |
is used by: Hypothesis Center is listed by: NIDDK Information Network (dkNET) is related to: Pancreatlas is related to: scPancMeta App is related to: PANC-DB has organization facet: HIRN Consortium on Beta Cell Death and Survival has organization facet: HIRN Consortium on Human Islet Biomimetics has organization facet: HIRN Consortium on Modeling Autoimmune Interactions has organization facet: HIRN Consortium on Targeting and Regeneration has organization facet: HIRN Human Pancreas Analysis Program has organization facet: HIRN Bioinformatics Center has organization facet: HIRN Coordinating Center has organization facet: HIRN Human Pancreas Analysis Consortium |
Type 1 diabetes, Diabetes | NIDDK | SCR_014393 | Human Islet Research Network | 2026-09-05 06:30:05 | 247 | |||||||
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The Pancreatic Beta-Cell Consortium Resource Report Resource Website 1+ mentions |
The Pancreatic Beta-Cell Consortium (RRID:SCR_016328) | PBC Consortium | data or information resource, data repository, disease-related portal, portal, service resource, storage service resource, topical portal | Portal to provide a repository for beta-cell data, to connect researchers from different backgrounds interested in contributing data, models and/or ideas for new insights into beta-cell biology. Used to understand beta-cell biology and diabetes through a cross-disciplinary approach for the assembly of spatiotemporal multi-scale whole cell models of human pancreatic beta-cells. | repository, pancreatic, Bcell, data, whole, cell, model, human, connect, contribute, model, idea, diabetes, integrate, approach, computation, design, effective, treatment, experiment, biology |
is related to: University of Southern California; Los Angeles; USA is related to: California Institute of Technology; Division of Biology is related to: University of California at Berkeley; Berkeley; USA is related to: Scripps Research Institute |
Diabetes | SCR_016328 | Pancreatic B Cell Consortium | 2026-09-05 06:28:07 | 5 | ||||||||
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Diabetes Epigenome Atlas Resource Report Resource Website 1+ mentions |
Diabetes Epigenome Atlas (RRID:SCR_016441) | atlas, data or information resource, database, disease-related portal, portal, topical portal | Collects and provides data on the human genome and epigenome to facilitate genetic studies of type 2 diabetes and its complications. A component of the AMP T2D consortium, which includes the National Institute for Diabetes and Digestive and Kidney Diseases (NIDDK) and an international collaboration of researchers. | collect, provide, data, human, genome, epigenome, genetic, study, type 2 diabetes |
has parent organization: Stanford University; Stanford; California has parent organization: University of California at San Diego; California; USA |
type 2 diabetes | NIDDK U01 DK100554 | Free, Proprietary data are available only to approved AMP consortium users with user accounts | SCR_016537 | SCR_016441 | 2026-09-05 06:28:08 | 2 | |||||||
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Viewbox4, Cephalometric software Resource Report Resource Website 1+ mentions |
Viewbox4, Cephalometric software (RRID:SCR_016481) | data analysis software, data processing software, image analysis software, software application, software resource | Software for cephalometric analysis. Customizable. Allows rendering, viewing and measuring of 3D data from CT scanners. Used in orthodontic departments for analysis of the dental and skeletal relationships of a human skull. | dHAL Software - The Company, cephalometric, analysis, rendering, viewing, measuring, data, CT scan, orthodontic, dental, skeletal, relationship, human, skull | Commercially available, Tutorial available | SCR_016481 | 2026-09-05 06:28:09 | 6 | |||||||||||
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JOINSOLVER Resource Report Resource Website |
JOINSOLVER (RRID:SCR_016619) | alignment software, data analysis software, data processing software, image analysis software, service resource, software application, software resource | Software tool to analyze human immunoglobulin V(D)J recombination and performing Ig nucleotide and amino acid alignment, as well as extensive mutation and Complementarity Determining Region 3 (CDR3H) analysis. | human, immunoglobulin, analysis, recombination, nucleotide, amino acid, alignment, mutation, CDR3H |
is listed by: NIDDK Information Network (dkNET) is listed by: NIAID |
DOI:10.4049/jimmunol.172.11.6790 | Free, Available for download, Freely available | https://dcb.cit.nih.gov/HTJoinSolver/ | SCR_016619 | 2026-09-05 06:28:11 | 0 | ||||||||
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AFIDs Resource Report Resource Website 1+ mentions |
AFIDs (RRID:SCR_016623) | AFIDs | continuing medical education, data processing software, image processing software, software application, software resource, software toolkit, training resource | Open framework for evaluating correspondence between brain images and teaching neuroanatomy. | evaluate, correspondence, magnetic, images, human, brain, fiducial, placement, neuroanatomy | DOI:10.1002/hbm.24693 | Free, Available for download, Freely available | SCR_016623 | Anatomical Fiducials | 2026-09-05 06:28:11 | 3 | ||||||||
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International Human Epigenome Consortium Resource Report Resource Website 10+ mentions |
International Human Epigenome Consortium (RRID:SCR_016937) | IHEC | consortium, data or information resource, organization portal, portal | Consortium to coordinate epigenome mapping and characterization worldwide to avoid redundant research effort, to implement high data quality standards, to coordinate data storage, management and analysis and to provide free access to the high resolution reference human epigenome maps for normal and disease cell types to the research community. Promotes data sharing. You may view, search and download the data already released by the different IHEC associated projects via the IHEC Data Portal. | reference, human, epigenome, map, normal, disease, cell, data, quality, standard, sharing |
is related to: 4D Nucleome is related to: Canadian Epigenetics, Environment and Health Research Consortium Network is parent organization of: International Human Epigenome Consortium Data Portal |
Free access to the research community, Open and controlled access to datasets according to policies and guidelines | https://epigenomesportal.ca/ihec/ | SCR_016937 | International Human Epigenome Consortium, IHEC | 2026-09-05 06:28:15 | 34 | |||||||
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Discovar assembler Resource Report Resource Website 10+ mentions |
Discovar assembler (RRID:SCR_016755) | Discovar | data analysis software, data processing software, sequence analysis software, software application, software resource | Software tool for variant calling with reference and de novo assembly of genomes. The heart of DISCOVAR is a de novo genome assembler which can generate de novo assemblies for both large and small genomes. | variant, calling, reference, de novo, assembly, genome, genetic, human, sequence, analysis |
is listed by: OMICtools has parent organization: Broad Institute |
NHGRI R01 HG003474; NHGRI U54 HG003067; NIAID HHSN272200900018C |
PMID:25326702 | Free, Available for download, Freely available | SCR_016755 | Discovar de novo, Discovar | 2026-09-05 06:28:14 | 20 | ||||||
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ValIdated Systematic IntegratiON of epigenomic data Resource Report Resource Website 10+ mentions |
ValIdated Systematic IntegratiON of epigenomic data (RRID:SCR_016921) | VISION | catalog, data or information resource, database, portal, project portal | International project to analyze mouse and human hematopoiesis, and provide a tractable system with clear clinical significance and importance to NIDDK. Collection of information from the flood of epigenomic data on hematopoietic cells as catalogs of validated regulatory modules, quantitative models for gene regulation, and a guide for translation of research insights from mouse to human. | analyze, mouse, human, hematopoietic, cell, blood, component, collection, epigenomic, data, catalog, gene, regulation | is listed by: NIDDK Information Network (dkNET) | National Institute for Diabetes and Digestive Diseases ; NIDDK ; NIH |
SCR_016921 | ValIdated Systematic IntegratiON of epigenomic data, ValIdated Systematic IntegratiON | 2026-09-05 06:28:15 | 11 | ||||||||
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GeneNest Resource Report Resource Website 1+ mentions |
GeneNest (RRID:SCR_007677) | data or information resource, database | GeneNest is a comprehensive visualization of gene indices of several organisms. The aim of GeneNest is to represent each gene by a single cluster of ESTs and/or mRNAs. Further subdivision of a cluster into contigs may be caused by alternative splicing, genomic sequences, or artifacts like chimeric sequences. Consensus sequence derived from GeneNest contigs are a basis for mapping genes onto the genome, and for analysis of splice isoforms. Organisms included are human, mouse, arabidopsis, zebrafish, drosophila, and sheep. human, mouse, arabidopsis, zebrafish, drosophila, sheep, EST, mRNA, alternative splicing, genomic sequences | est, alternative splicing, arabidopsis, drosophila, genomic sequences, human, mouse, mrna, sheep, zebrafish | has parent organization: Max Planck Institute for Molecular Genetics; Berlin; Germany | nif-0000-02883 | SCR_007677 | GeneNest | 2026-09-05 06:31:42 | 5 | |||||||||
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Human Gene Expression Index Resource Report Resource Website 1+ mentions |
Human Gene Expression Index (RRID:SCR_007726) | data or information resource, database | The Human Gene Expression Index (HuGE Index) aims to provide a comprehensive database to further our understanding of the expression of human genes in normal human tissues. mRNA expression levels of thousands of genes are obtained using high-density oligonucleotide array technology and used to create a public database. The website also provides interactive tools for researchers to query and visualize data over the Internet. To facilitate data analysis, genes are alsocross-referenced with their annotation in the LocusLink database at NCBI. | human, human genome | nif-0000-02991 | http://www.hugeindex.org | SCR_007726 | HUGE Index | 2026-09-05 06:31:43 | 4 | |||||||||
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Homophila Resource Report Resource Website |
Homophila (RRID:SCR_007717) | data or information resource, database | THIS RESOURCE IS NO LONGER IN SERVICE, documented on June 23, 2013. Homophila utilizes the sequence information of human disease genes from the NCBI OMIM (Online Mendelian Inheritance in Man) database in order to determine if sequence homologs of these genes exist in the current Drosophila sequence database (FlyBase). Sequences are compared using NCBI's BLAST program. The database is updated weekly and can be searched by human disease, gene name, OMIM number, title, subtitle and/or allelic variant descriptions. | homolog, human disease, human disease gene, human, gene, cognate |
is related to: OMIM has parent organization: University of California at San Diego; California; USA |
NCRR P 41 RR08605-06 | PMID:11752278 PMID:11381037 |
THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-02976 | SCR_007717 | Human disease to drosophila database | 2026-09-05 06:31:43 | 0 | ||||||
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Alternate splicing gallery Resource Report Resource Website 1+ mentions |
Alternate splicing gallery (RRID:SCR_008129) | data or information resource, database | Alternative splicing essentially increases the diversity of the transcriptome and has important implications for physiology, development and the genesis of diseases. This resource uses a different approach to investigate alternative splicing (instead of the conventional case-by case fashion) and integrates all transcripts derived from a gene into a single splicing graph. ASG is a database of splicing graphs for human genes, using transcript information from various major sources (Ensembl, RefSeq, STACK, TIGR and UniGene). Each transcript corresponds to a path in the graph, and alternative splicing is displayed by bifurcations. This representation preserves the relationships between different splicing variants and allows us to investigate systematically all possible putative transcripts. Web interface allows users to display the splicing graphs, to interactively assemble transcripts and to access their sequences as well as neighboring genomic regions. ASG also provide for each gene, an exhaustive pre-computed catalog of putative transcriptsin total more than 1.2 million sequences. It has found that ~65 of the investigated genes show evidence for alternative splicing, and in 5 of the cases, a single gene might produce over 100 transcripts. | gallery, gene, genesis, alternative, development, disease, diversity, genomic, human, physiology, putative transcript, sequence, single, splice, splicing graph, transcript, transcriptome, variant, bio.tools |
is listed by: bio.tools is listed by: Debian |
nif-0000-20932, biotools:alternative_splicing_gallery | https://bio.tools/alternative_splicing_gallery | SCR_008129 | ASG | 2026-09-05 06:31:50 | 1 | ||||||||
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CRE Binding-protein Target Gene Database Resource Report Resource Website 10+ mentions |
CRE Binding-protein Target Gene Database (RRID:SCR_008027) | data or information resource, database | CREB target gene database that uses a multi-layered approach to predict, validate and characterize CREB target genes. For each gene, the database tries to provide the following information: 1. CREB binding sites on the promoters 2. Promoter occupancy by CREB 3. Gene activation by cAMP in tissues CREB seems to occupy a large number of promoters in the genome (up to ~5000 in human), and the profiles for CREB promoter occupancy are very similar in different human tissues. However, only a small proportion of CREB occupied genes are induced by cAMP in any cell type, possibly reflecting the requirement of additional regulatory partners that assist in recruitment of the transcriptional apparatus. To use the database, choose the species, select the table you want to search, leave field (''All'') and type in the gene you want to search. A table listing the search results will be returned, followed by the description of the table. If no search result is returned, try the official gene symbol or gene ID (locuslink number) from NCBI Entrez Gene to search. Sponsors: This work was supported by National Institutes of Health Grants GM RO1-037828 (to M.M.) and DK068655 (to R.A.Y.). | expression, gene, activation, camp, camp-response element binding protein (creb), cell, cellular, coactivator, cyclic amp response element binding protein, hormone, human, in vivo, methylation, mouse, nutrient, phosphorylation, promoter, rat, regulatory, rna, signaling, target gene, tissue, transcription, FASEB list | nif-0000-10201 | SCR_008027 | CREB Database | 2026-09-05 06:31:49 | 31 | ||||||||||
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National Institute on Aging, Database of Longitudinal Studies Resource Report Resource Website |
National Institute on Aging, Database of Longitudinal Studies (RRID:SCR_008259) | data or information resource, database | THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 11, 2015. A searchable database for epidemiologic research on aging changes across the lifespan. In 2003, the National Institute on Aging (NIA) established the Longitudinal Data on Aging (LDA) working group to assist with the development of research initiatives for identifying the physiologic and other types of factors across the lifespan, affecting onset and progression of disease with advancing age, as well as elucidation of protective factors contributing to exceptionally healthy aging. This database was developed based on input from the LDA working group which indicated that establishing a database of existing sources of longitudinal data on aging (e.g., ongoing longitudinal cohorts, longitudinal data sets, biospecimen repositories) would be a valuable resource for facilitating future research on aging changes across the lifespan. The longitudinal studies, data sets and repositories included in this database encompass a wide range of age groups (childhood to old age), studies in minority populations, as well as sources of longitudinal data existing in the United States and abroad. Our primary purpose for establishing this database is to provide a resource for potential applicants for grants to the NIA. No part of this database can be used for commercial purposes. | epidemiologic, healthy aging, human, lifespan, longitudinal, onset, progression of disease, protective factors | Aging | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-22594 | SCR_008259 | Database of Longitudinal Studies | 2026-09-05 06:31:52 | 0 | ||||||||
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Cytokine Family Database Resource Report Resource Website 1+ mentions |
Cytokine Family Database (RRID:SCR_008134) | data or information resource, database | THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 26, 2016. A collection of cDNA, gene and protein records of cytokines deposited in public databases provides various information about the cytokine members of vertebrates in other databases including NCBI GenBank, Swiss-Prot, UniGene, TIGR (The Institute for Genomic Research) Gene Indices, Ensembl, Entrez Gene, Mouse Genome Informatics (MGI) and Rat Genome Database (RGD). It also provides orthologous relationship of cytokine members and includes novel members identified in the databases. | family, fish, gene, amphibian, bird, cdna, chemokine, cow, cytokine, genome, human, mammalian, mouse, oncogene, phylogenetic, protein, rat, receptor, reptile, virus |
is listed by: 3DVC has parent organization: Kumamoto University; Kumamoto; Japan |
Japan Society for the Promotion of Science | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-20948 | http://cytokine.medic.kumamoto-u.ac.jp/ | SCR_008134 | dbCFC | 2026-09-05 06:31:50 | 1 | ||||||
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Animal Genome Database Resource Report Resource Website 1+ mentions |
Animal Genome Database (RRID:SCR_008165) | data or information resource, database | Database of comparative gene mapping between species to assist the mapping of the genes related to phenotypic traits in livestock. The linkage maps, cytogenetic maps, polymerase chain reaction primers of pig, cattle, mouse and human, and their references have been included in the database, and the correspondence among species have been stipulated in the database. AGP is an animal genome database developed on a Unix workstation and maintained by a relational database management system. It is a joint project of National Institute of Agrobiological Sciences (NIAS) and Institute of the Society for Techno-innovation of Agriculture, Forestry and Fisheries (STAFF-Institute), under cooperation with other related research institutes. AGP also contains the Pig Expression Data Explorer (PEDE), a database of porcine EST collections derived from full-length cDNA libraries and full-length sequences of the cDNA clones picked from the EST collection. The EST sequences have been clustered and assembled, and their similarity to sequences in RefSeq, and UniGene determined. The PEDE database system was constructed to store sequences and similarity data of swine full-length cDNA libraries and to make them available to users. It provides interfaces for keyword and ID searches of BLAST results and enables users to obtain sequence data and names of clones of interest. Putative SNPs in EST assemblies have been classified according to breed specificity and their effect on coding amino acids, and the assemblies are equipped with an SNP search interface. The database contains porcine nucleotide sequences and cDNA clones that are ready for analyses such as expression in mammalian cells, because of their high likelihood of containing full-length CDS. PEDE will be useful for researchers who want to explore genes that may be responsible for traits such as disease susceptibility. The database also offers information regarding major and minor porcine-specific antigens, which might be investigated in regard to the use of pigs as models in various medical research applications. | est, expression, gene, amino acid, animal, antigen, breed, cattle, cdna, cell, chain, clone, coding, cytogenetic, genome, human, linkage, livestock, mammalian, map, mouse, nucleotide, organism, phenotypic, pig, polymerase, porcine, primer, reaction, sequence, snp, specie, swine, trait | has parent organization: National Institute of Agrobiological Sciences; Ibaraki; Japan | nif-0000-21029 | SCR_008165 | AGP | 2026-09-05 06:31:50 | 1 | |||||||||
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Comparative Vertebrate Sequencing Resource Report Resource Website |
Comparative Vertebrate Sequencing (RRID:SCR_008213) | data or information resource, database | Generates data for use in developing and refining computational tools for comparing genomic sequence from multiple species. The NISC Comparative Sequencing Program's goal is to establish a data resource consisting of sequences for the same set of targeted genomic regions derived from multiple animal species. The broader program includes plans for a diverse set of analytical studies using the generated sequence and the publication of a series of papers describing the results of those analysis in peer-reviewed journals in a timely fashion. Experimentally, this project involves the shotgun sequencing of mapped BAC clones. For each BAC, an assembly is first performed when a sufficient number of sequence reads have been generated to provide full shotgun coverage of the clone. At that time, the assembled sequence is submitted to the HTGS division of GenBank. Subsequent refinements of the sequence, including the generation of higher-accuracy finished sequence, results in the updating of the sequence record in GenBank. By immediately submitting our BAC-derived sequences to GenBank, it makes their data available as a public service to allow colleagues to speed up their research, consistent with the now well-established routine of sequencing centers participating in the Human Genome Project. However, at the same time, it has made considerable investment in acquiring these mapping and sequence data, including sizable efforts of graduate students, postdoctoral fellows, and other trainees. Furthermore, in most cases, large data sets involving multiple BAC sequences from multiple species must first be generated, often taking many months to accumulate, before the planned analysis can be performed and the resulting papers written and submitted for publication. | accuracy, animal, bac, clone, comparative, computational, genome, genomic, human, map, mapping, model organisms and comparative genomics databases, sequence, specie, tool | has parent organization: National Institutes of Health | nif-0000-21291 | SCR_008213 | Comparative Vertebrate Sequencing | 2026-09-05 06:31:51 | 0 | |||||||||
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Structure modeling of 907 G protein coupled receptors in the human genome Resource Report Resource Website 1+ mentions |
Structure modeling of 907 G protein coupled receptors in the human genome (RRID:SCR_008351) | data or information resource, database | THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 19,2019.Database of tertiary structural modeling results of threading assembly refinement (TASSER) method for all 907 G protein-coupled receptors (GPCRs) in human genome. All sequences were collected from GPCR database http://www.gpcr.org/7tm/ and http://www.expasy.org/cgi-bin/lists?7tmrlist.txt. Unlike traditional homology modeling approaches, TASSER modeling does not require solved homologous template structures; moreover, it often refines the structures closer to native. G protein-coupled receptors (GPCRs), encoded by about 5% of human genes, comprise the largest family of integral membrane proteins and act as cell surface receptors responsible for the transduction of endogenous signal into a cellular response. Although tertiary structural information is crucial for function annotation and drug design, there are few experimentally determined GPCR structures. To address this issue, we employ the recently developed threading assembly refinement (TASSER) method to generate structure predictions for all 907 putative GPCRs in the human genome. Unlike traditional homology modeling approaches, TASSER modeling does not require solved homologous template structures; moreover, it often refines the structures closer to native. These features are essential for the comprehensive modeling of all human GPCRs when close homologous templates are absent. Based on a benchmarked confidence score, approximately 820 predicted models should have the correct folds. The majority of GPCR models share the characteristic seven-transmembrane helix topology, but 45 ORFs are predicted to have different structures. This is due to GPCR fragments that are predominantly from extracellular or intracellular domains as well as database annotation errors. Our preliminary validation includes the automated modeling of bovine rhodopsin, the only solved GPCR in the Protein Data Bank. With homologous templates excluded, the final model built by TASSER has a global C(alpha) root-mean-squared deviation from native of 4.6 angstroms, with a root-mean-squared deviation in the transmembrane helix region of 2.1 angstroms. Models of several representative GPCRs are compared with mutagenesis and affinity labeling data, and consistent agreement is demonstrated. Structure clustering of the predicted models shows that GPCRs with similar structures tend to belong to a similar functional class even when their sequences are diverse. These results demonstrate the usefulness and robustness of the in silico models for GPCR functional analysis. Sponsors: GPCR is funded by the University at Buffalo, Buffalo, New York. | endogenous, extracellular, family, functional, gene, cellular, couple, genome, gpcr, g protein, helix, homology, human, membrane, model, modeling, orf, protein, receptor, response, signal, structural, structural model, structure, template, tertiary, topology, transduction, transmembrane | has parent organization: Georgia Institute of Technology; Georgia; USA | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-25215 | SCR_008351 | GPCR | 2026-09-05 06:31:52 | 3 |
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The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
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