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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
A biorepository of human biological material from healthy and diseased populations with a special focus on subjects with Alzheimer's disease, multiple sclerosis, Parkinson's disease and other neurological disorders. Data is collected longitudinally. PrecisionMed aims to facilitate research in genetics, drug discovery, biomarker research and molecular diagnostics. Materials collected include DNA, RNA, plasma and cerebrospinal fluid, among others.
Proper citation: PrecisionMed (RRID:SCR_010486) Copy
Tissue bank that specifically provides human tissue and cell samples for research purposes. It offers PBMCs, whole blood, solid tumor tissues, circulating tumor cells, and a variety of other bio-specimens.
Proper citation: Conversant Biologics Inc. (RRID:SCR_010675) Copy
MindSpec is a nonprofit organization that utilizes innovative bioinformatics strategies to accelerate research on common neurodevelopmental disorders. With our research we hope to foster discovery and development of treatments that alleviate the symptoms of affected individuals. Our core mission at MindSpec is to advance research on neurodevelopmental conditions. Founded in 2006, MindSpec is an independent, non-profit research organization established to facilitate the discovery of a cure for autism. Although the initial focus was autism, we have gradually expanded our scope to other neurological disorders. We develop bioinformatics strategies using current information technology platforms to build disease specific databases. At MindSpec we place a strong emphasis on translational research, that is, closing the gap between basic science discoveries and practical treatments with the potential of benefiting people who have autism. Goals: * Build an integrated, up-to-date, relevant, searchable resource on autism, AutDB. * Build a community of scientists, practitioners, educators, policymakers and people affected by autism to share and disseminate knowledge of autism. * Identify gaps in autism research around the world. * Identify priority areas in autism research based on real-world needs. * Build an autism dictionary and digital information library. * Address cultural differences in treatments for autism, a social disease. * Build knowledge about autism for immediate use.
Proper citation: MindSpec: Informatics for Neurodevelopmental Conditions (RRID:SCR_004439) Copy
CRBS is a UCSD organized research unit (ORU) that exists to provide human resources, high technology equipment, and administrative services to researchers engaged in fundamental research on cell structure and function relationships in central nervous system processes, cardiovascular networking, and muscular contraction through multiple scales and modalities. CRBS scientists investigate these processes through invention, refinement, and deployment of sophisticated technologies, especially: - High-powered electron microscopes that reveal three-dimensional cell structures - State-of-the-art X-ray crystallography and magnetic resonance analysis that provide detail on protein structures at high-resolution - Laser-scanning and confocal light microscopes that reveal molecules tagged with fluorescent markers as they traffic within cells and pass transfer signals within and between cells - High performance computing and grid-based integration of distributed data CRBS facilitates an interdisciplinary infrastructure in which people from biology, medicine, chemistry, and physics can work with those from computer science and information technologies in collaborative research. Researchers share interests in the study of complex biological systems at many scales, from the structures of enzymes, proteins, and the body's chemical communications network at atomic and molecular levels, to an organism's physiology, strength, and support at cellular and tissue levels. The CRBS infrastructure integrates resources for high-performance computing, visualization, and database technologies, and the grid-integration of large amounts of archival storage data. The California Institute for Telecommunications and Information Technology (Cal-IT2) and the San Diego Supercomputer Center (SDSC) are collaborators in simulating the activity of biological systems, analyzing the results, and organizing the growing storehouse of biological information. CRBS is an entity evolving as research evolves. It forges interactions with biotechnology and biocomputing companies for technology transfer. Interaction, collaboration, and multiscale research produce new perspectives, reveal fruitful research topics, lead to the development of new technologies and drugs, and train a new generation of researchers in biological systems. Sponsors: CRBS is supported by the University of California at San Diego.
Proper citation: Center for Research in Biological Systems (RRID:SCR_002666) Copy
https://dgrc.bio.indiana.edu/Home
Serves Drosophila research community by collecting and distributing DNA clones and vectors; collecting and distributing Drosophila cell lines; developing and testing genomics technologies for use in Drosophila and assisting members of the research community in their use.
Proper citation: Drosophila Genomics Resource Center (RRID:SCR_002845) Copy
Created by the Government of Canada in 1997 to undertake world-class research and technology development to benefit Canadians by investing in facilities and equipment, universities, colleges, research hospitals and non-profit research institutions to attract and retain the world's top talent, training the next generation of researchers, supporting private-sector innovation and creating high-quality jobs.
Proper citation: Canada Foundation for Innovation (RRID:SCR_005054) Copy
Offer biorepository services to public and private research institutes, to the highest standards of quality and safety with the aim of contributing to the advancement of medical research and scientific discovery. The BioRep Cell Repository establishes, maintains and distributes cell line cultures as well as DNA derived from these cultures. The scientific and business affiliation between BioRep and Coriell allows access to more than a million types of cell vials, stored in liquid nitrogen. Cells that have been stored for nearly 50 years, are still viable and available for research purposes today. Thanks to an exclusive agreement with the Coriell Institute for Medical Research, the oldest and largest biorepository of the world, BioRep is specialized in cell lines preparation, in nucleic acid extraction and long term storage in liquid nitrose (-196 degrees C) and in refrigerators (-80 degrees C) of any kind of biosamples, using procedures and standards developed by the Coriell in over 50 years of activity. BioRep and Coriell together constitute one of the few Global Biorepository able to serve the pharmaceutical industries for world wide clinical trials. BioRep facility is specifically designed to give the utmost efficiency and security by implementing Coriell procedures and standards. The BioRep Tissue Repository provides safe and secure storage of tissue specimens as required for medical research and scientific investigation. All tissues are preserved with the most current preservation techniques and processes. In addition to the storage service, BioRep provides Cell Biology, Molecular Biology, Microbiology services developed in ISO 9001:2008 certified laboratories.
Proper citation: BioRep (RRID:SCR_004907) Copy
The Digital Enterprise Research Institute is an internationally recognized institute in semantic web research, education and technology transfer. DERI brings together academic and industrial partners to boost innovation in science and technology, which directly contributes to the Irish government''s plan of transforming Ireland into a competitive knowledge economy.
Proper citation: Digital Enterprise Research Institute (RRID:SCR_004802) Copy
Center dedicated to understanding and treatment of neurological diseases by creating and using imaging methods to study human nervous system. Dedicated to research imaging of human brain. Brain structure is imaged using anatomical Magnetic Resonance Imaging (aMRI) while brain physiology is imaged using Positron Emission Tomography (PET), Magnetic Resonance Spectroscopy (MRS), functional MRI (fMRI) and magnetoencephalography (MEG). BIC maintains linkages with clinical, clinical research and basic research communities within Montreal Neurological Institute (MNI), McGill University and has collaborations across Quebec, Canada, USA and internationally.
Proper citation: McConnell Brain Imaging Center (RRID:SCR_008364) Copy
It was created to serve as a gateway to alternatives news, information, and resources on the Internet and beyond. Altweb now is the U.S. home of the journal ALTEX: Alternatives to Animal Experimentation, which is the official publication of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT). Altweb is intended to serve: *Biomedical researchers *Industry *The international alternatives community *The international regulatory community(ies) *IACUCs and other institutional groups that review animal protocols *The animal welfare community *Individuals and groups who work with laboratory animals (technicians, veterinarians, etc.) *Educators *Students *The general public Altweb has five practical goals: 1. To assist scientists and others seeking to conduct a search for alternatives methods. 2. To serve as a CRPcentral reference pointfor alternatives information, publications, databases, calendars, and other resources. 3. To support the creation and maintenance of new alternative resources as needed, when no other organization can/will do so. 4. To promote the use of alternatives resources by publicizing them on the site and through e-mail or other outreach. 5. To facilitate communication and collaboration among members of the alternatives community, in particular those who work in database or information management.
Proper citation: Atlweb: Alternatives to Animal Testing (RRID:SCR_007265) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. Neuropsychiatric Imaging Research Laboratory (NIRL) analyze magnetic resonance images to research numerous psychiatric disorders including depression, bipolar disorder, and post traumatic stress disorder. NIRL also develop new methods for MR image processing to improve quality and reliability of research in the field of neuroimaging. The laboratory computer resources include Sun MicroSystems SPARC workstations, Windows PCs, over 3 terabytes of online hard disk space, and a web server system. The lab has a site filtered anonymous ftp server system for data transfer. There are individual offices for visiting fellows and analysts for image processing as well as shared work-study rooms and conference facilities.
Proper citation: Duke University Medical Center Neuropsychiatric Imaging Research Laboratory (RRID:SCR_007124) Copy
http://www.uwstructuralgenomics.org/
It is a specialized research center supported by the Protein Structure Initiative (PSI) of the National Institute of General Medical Sciences (NIGMS), one of the National Institutes of Health (NIH). PSI is a federal, university, and industry effort aimed at dramatically reducing the costs and lessening the time it takes to determine a three-dimensional protein structure. The long-range goal of PSI is to solve 10,000 protein structures in 10 years and to make the three-dimensional atomic-level structures of most proteins easily obtainable from knowledge of their corresponding DNA sequences. CESG is located within the Department of Biochemistry at the University of Wisconsin-Madison (Madison, WI) and the Department of Biochemistry at the Medical College of Wisconsin (Milwaukee, WI). CESG develops new methods and technologies to address unique eukaryotic bottlenecks and disseminates its methodologies and experimental results to the scientific community worldwide through: :- Cell-Free Protein Production Workshops :- Plasmids at PSI Materials Repository :- Posters Presented at Scientific Meetings :- Publications in PubMed / PubMed Central :- Sesame (LIMS) Available for Researchers :- Solved Structures in the Protein Data Bank :- Technology Dissemination Reports They have welcomed requests by researchers to solve eukaryotic protein structures, particularly medically relevant proteins, through our Online Structure Request System for Researchers. They have solved many community-nominated targets and deposited information about these targets in public databases and published on our investigations and findings. Sponsors: CESG is supported by NIH / NIGMS Protein Structure Initiative grant numbers U54 GM074901 and P50 GM064598.
Proper citation: CESG (RRID:SCR_008451) Copy
A research program of the NIA which focuses on neuroscience, aging biology, and translational gerontology. The central focus of the program's research is understanding age-related changes in physiology and the ability to adapt to environmental stress, and using that understanding to develop insight about the pathophysiology of age-related diseases. The IRP webpage provides access to other NIH resources such as the Biological Biochemical Image Database, the Bioinformatics Portal, and the Baltimore Longitudinal Study of Aging., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Intramural Research Program (RRID:SCR_012734) Copy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860449/
Collection of far reaching initiatives designed to transform research capabilities and improve translation of research into practice. Program consists of three major themes: new pathways to discovery, research teams of future, and reengineering clinical research enterprise.
Proper citation: NIH Roadmap (RRID:SCR_011465) Copy
http://www.ncbi.nlm.nih.gov/pubmedhealth/
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on September 9, 2022. A consumer health database that provides up-to-date information on diseases, conditions, injuries, drugs, supplements, treatment options, and healthy living, with a special focus on comparative effectiveness research from institutions around the world. PubMed Health includes * consumer guides summarizing comparative effectiveness research * fact sheets on diseases and conditions * information on drugs and supplements * encyclopedic overviews of health topics * links to external Web sites PubMed Health has a special focus on comparative effectiveness research, in particular that research which evaluates the available evidence of the benefits and harms of different treatment options for different groups of people. In Comparative Effectiveness Research, experts often synthesize the evidence from dozens, or even hundreds, of individual studies.
Proper citation: PubMed Health (RRID:SCR_000512) Copy
http://researchprojects.kth.se/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. The KTH Research Project Database is intended to contain all the currently on-going projects at KTH. Sponsors: This resource is supported by the Royal Institute of Technology, Sweden,
Proper citation: Royal Institute of Technology: Research Project Database (RRID:SCR_000751) Copy
A database of neuroscience-related concepts that utilizes visualization tools for the purpose of research, education and knowledge discovery. The data comes from PubMed abstracts and an algorithm that assumes related terms will appear together. The topics can include computational modeling, behavioral functions and neurological degeneration.
Proper citation: brainSCANr (RRID:SCR_000500) Copy
http://neurosurgery.ucsf.edu/index.php/research_tissue_bank.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 4th,2023. Brain Tumor Research Center Tissue Bank began collecting tissue in 1978 and has established an organized repository of characterized tissues--frozen, paraffin-embedded, blood and cultures--that are maintained in a manner useful for a wide range of studies. Samples are collected only from patients who have agreed to have their tissues banked and used for future research. Consent documents are maintained in a secure area and associated clinical data are held in a double-password protected computer database. Each sample received into the Tissue Bank is non-identifying number. No protected health information (PHI) is released. To obtain samples, investigators submit a request form to the Manager. The request form requires an explanation of the tissue requested (type, number of samples, justification), description of the study, CHR approval (see new policy regarding human vs. non-human research) and Project Leader authorization. The Manager reviews each request for feasibility before presentation to the Scientific Core Committee. The UCSF Neurosurgery Tissue Bank makes its inventory of stock cell lines available to all investigators. Requested cells are grown in T-25 flasks and shipped FedEx Priority Overnight at the receipient's expense. However, if you prefer, we can ship the frozen cells, packed in dry ice. (Note: some countries restrict dry ice shipments.)
Proper citation: UCSF Brain Tumor Tissue Bank (RRID:SCR_000647) Copy
https://www.jax.org/news-and-insights/2004/june/app-mouse-models-for-alzheimers-disease-research
An information resource about several models for mice to develop Alzheimer's-related characteristics as they age.
Proper citation: Mouse Models For Alzheimer's Disease Research (RRID:SCR_000708) Copy
http://www.calacademy.org/academy/blogs/
Academy scientists, journalists, adventurers and other staff members are blogging their stories and inviting questions and comments. Read current science news, hear from researchers in the field (Philippines, Sao Tome, Papua New Guinea), ask a question of an Academy naturalist, and much more.
Proper citation: California Academy of Sciences Blogs (RRID:SCR_000694) Copy
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