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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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Abgent Resource Report Resource Website 50+ mentions |
Abgent (RRID:SCR_008393) | commercial organization | Antibody supplier. | antibody, peptide, synthesis, protein, primary antibody, reagent, peptide synthesis, cell signaling, post-translational modification, stem cell, neuronal development, neurodegenerative disease, gene regulation, development, autophagy, apoptosis, stem cell, phosphorylation, cell function, gene, regulation, research, library, human, kinome, cdna clone, rnai, tissue, cell | is listed by: ScienceExchange | nif-0000-30051, SciEx_4353 | https://www.abcepta.com/ | SCR_008393 | Abgent Antibodies and Peptides, Abcepta | 2026-09-05 06:26:22 | 67 | ||||||||
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Caribbean Primate Research Center Resource Report Resource Website 1+ mentions |
Caribbean Primate Research Center (RRID:SCR_008345) | CPRC | biomaterial supply resource, material resource, organism supplier | Center for the study of non-human primates. Its mission is the study and use of non-human primates as models for studies of social and biological interactions and for the discovery of methods of prevention, diagnosis and treatment of diseases that afflict humans. Through the stewardship of three unique facilities—Cayo Santiago Field Station, Sabana Seca Field Station, and the Laboratory of Primate Morphology supports a diverse range of research programs that enhance understanding of primate biology and behavior, with direct applications in biomedical and translational research. | NPRC, NPRC Consortium, ORIP, environment, genetic, antigen, behavior, biological, biomedical, birth, blood, conception, dengue, disease, human, immune system, laboratory, macaca mulatta, macaque, model, monkey, morphology, movement, pathology, primate, reproductive biology, researcher, rh, rhesus, scientific, serological, siv, skeletal system, vaccine, variation, virology |
is listed by: National Primate Research Center Consortium has parent organization: University of Puerto Rico; Puerto Rico; USA |
NIH Office of the Director P40 OD012217 | nif-0000-25870 | https://orip.nih.gov/comparative-medicine/programs/vertebrate-models | SCR_008345 | Caribbean Primate Research Center Program | 2026-09-05 06:26:21 | 7 | ||||||
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Southwest National Primate Research Center Resource Report Resource Website 50+ mentions |
Southwest National Primate Research Center (RRID:SCR_008292) | data or information resource, portal, topical portal | Center that supports studies of nonhuman primate models of human diseases, including common chronic diseases and infectious diseases and the effects that genetics and the environment have on physiological processes and disease susceptibility. SNPRC encourages the use of its resources by investigators from the national and international biomedical research communities. | NPRC, NPRC Consortium, ORIP, environment, genetic, aids, animal, baboon, biomedical, breeding, chimpanzee, chronic, colony, disease, human, infectious, macaques, marmoset, nonhuman, physiological, population, primate, process, research, rhesus, specie, study, susceptibility, veterinary, spf, specific, pathogen, free |
is listed by: National Primate Research Center Consortium has parent organization: Texas Biomedical Research Institute; Texas; USA |
NIH Office of the Director P51 OD011133; NIH Office of the Director U42 OD010442 |
nif-0000-24359 | https://orip.nih.gov/comparative-medicine/programs/vertebrate-models | SCR_008292 | SNPRC | 2026-09-05 06:26:20 | 90 | |||||||
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OpenTox Framework Resource Report Resource Website |
OpenTox Framework (RRID:SCR_008686) | OT | data or information resource | Tools for the integration of data from various sources (public and confidential), for the generation and validation of computer models for toxic effects, libraries for the development and seamless integration of new algorithms, and scientifically sound validation routines. The goal of OpenTox is to develop an interoperable predictive toxicology framework which may be used as an enabling platform for the creation of predictive toxicology applications. OpenTox is relevent for users from a variety of research areas: Toxicological and chemical experts (e.g. risk assessors, drug designers, researchers) computer model developers and algorithm developers non specialists requiring access to Predictive Toxicology models and data OpenTox applications can combine multiple web services providing users access to distributed toxicological resources including data, computer models, validation and reporting. Applications are based on use cases that satisfy user needs in predictive toxicology. OpenTox was initiated as a collaborative project involving a combination of different enterprise, university and government research groups to design and build the initial OpenTox framework. Additionally numerous organizations with industry, regulatory or expert interests are active in providing guidance and direction. The goal is to expand OpenTox as a community project enabling additional expert and user participants to be involved in developments in as timely a manner as possible. To this end, our mission is to carry out developments in an open and transparent manner from the early days of the project, and to open up discussions and development to the global community at large, who may either participate in developments or provide user perspectives. Cooperation on data standards, data integration, ontologies, integration of algorithm predictions from different methods, and testing and validation all have significant collaboration opportunities and benefits for the community. OpenTox is working to meet the requirements of the REACH legislation using alternative testing methods to contribute to the reduction of animal experiments for toxicity testing. Relevant international authorities (e.g., ECB, ECVAM, US EPA, US FDA) and industry organizations participate actively in the advisory board of the OpenTox project and provide input for the continuing development of requirement definitions and standards for data, knowledge and model exchange. OpenTox actively supports the development and validation of in silico models and algorithms by improving the interoperability between individual systems (common standards for data and model exchange), increasing the reproducibility of in silico models (by providing a quality source of structures, toxicity data and algorithms) and by providing scientifically sound and easy-to-use validation routines. OpenTox is committed to the support and integration of alternative testing methods using in vitro assay approaches, systems biology, stem cell technology, and the mining and analysis of human epidemiological data. Hence the framework design must take into account extensibility to satisfy a broad range of scientific developments and use cases. | drug, epidemiolgical, experiment, framework, alogrithm, animal, application, assay, chemical, computer, data, human, interoperable, in vitro, knowledge, method, mining, model, platform, researcher, stem cell, systems biology, technology, testing, toxicicty, toxicology, validation, ontology | European Union FP7 | nif-0000-33775 | SCR_008686 | 2026-09-05 06:26:26 | 0 | |||||||||
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PATHONET Resource Report Resource Website 1+ mentions |
PATHONET (RRID:SCR_008674) | data or information resource, portal, topical portal | PathoNet is a virtual meeting place for pathologists from all over the world. They can use it as a virtual pathology laboratory in which they can exchange their views on their cases. Join us and share your experience. Special or rare cases maybe very useful in the diagnostic practice. Everybody who would like to use digital microscopy in human, veterinary or forensic pathology; in laboratory medicine, in human anatomy; in experimental research, and when teaching can benefit from this resource. Additionally, practicing physicians, students, tutors, experts and researchers can all contribute and benefit from PathoNet. Sponsors: This resource is supported by 3DHISTECH Ltd. | experimental, expert, forensic pathology, anatomy, diagnostic, human, laboratory, medicine, pathologist, pathology, physician, researcher, student, teaching, virtual, meeting | nif-0000-33424 | SCR_008674 | PathoNet | 2026-09-05 06:26:26 | 6 | ||||||||||
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Moffitt Cancer Center Resource Report Resource Website 1+ mentions |
Moffitt Cancer Center (RRID:SCR_008730) | Moffitt | institutional portal | H. Lee Moffitt Cancer Center & Research Institute has made a lasting commitment to the prevention and cure of cancer, working tirelessly in the areas of patient care, research and education to advance one step further in fighting this disease. As part of an elite group of National Cancer Institute (NCI) Comprehensive Cancer Centers, Moffitt focuses on the development of early stage translational research aimed at the rapid translation of scientific discoveries to benefit patient care. Since the first patient admission in October 1986, Moffitt physicians, scientists and staff members have worked together to establish a tradition of excellence offered in an atmosphere characterized by kindness, caring and hope. The Cancer Center''s future growth in clinical care and research rests firmly on this tradition and makes possible the changes ahead. The mission of Moffitt Cancer Center is to contribute to the prevention and cure of cancer. Moffitt''s vision is to be the leader in scientific discovery and translation into compassionate care, cures, and prevention of cancer for our community and the world. As it grows to fulfill its mission, the Cancer Center will continue to be distinguished by its compassionate and effective patient care. Moffitt Cancer Center is a not-for-profit institution. It includes private patient rooms, the Southeast''s largest Blood and Marrow Transplant Program, outpatient treatment programs that record more than 320,500 visits a year, the Moffitt Research Center, Moffitt Cancer Center at International Plaza and the Lifetime Cancer Screening & Prevention Center. | cancer, human |
has parent organization: University of South Florida; Florida; USA is parent organization of: Moffitt Cancer Center Tissue Core is parent organization of: Moffitt Cancer Center Proteomics and Metabolomics Core Facility is parent organization of: Moffitt Cancer Center Tissue Core Facility is parent organization of: Moffitt Cancer Center Small Animal Imaging Laboratory Core Facility is parent organization of: Moffitt Cancer Center Molecular Genomics Core Facility is parent organization of: Moffitt Cancer Center Molecular Genomics Core Facility |
NCI | nlx_143722 | SCR_008730 | H. Lee Moffitt Cancer Center and Research Institute, H. Lee Moffitt Cancer Center & Research Institute | 2026-09-05 06:26:27 | 5 | |||||||
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BrainVoyager: Talairach Brain Atlas Resource Report Resource Website |
BrainVoyager: Talairach Brain Atlas (RRID:SCR_008800) | BV Talairach Brain Atlas | atlas, data or information resource, data processing software, data visualization software, reference atlas, software application, software resource, talairach-tournoux atlas | The Talairach brain atlas visualized via BrainVoyager (Commercial software) can be used to visualize Brodmann areas as they were defined for the Talairach brain (Talairach & Tournaux, 1988) and to compare regions of subjects with respect to the Brodmann areas. The demarcated areas are based on the Talairach demon, which is a digitized version of the Talairach atlas and which has been transferred into BrainVoyager VOI files by Matthias Ruf, Mannheim. Using the Brodman.voi file you may ask questions like the following: What is the signal time course of subject N in experiment A within Brodmann area X ?. Note, however, that the defined areal boundaries should be used only as a rough guideline for determining the location of activated regions: There is substantial variation of histologically defined areas between subjects. Since cytoarchitectonically defined Brodmann areas are not available in vivo, we advise to use the provided information with care. The TalairachBrain.vmr file is located in the same folder as your BrainVoyager executable file. It can be loaded as any VMR project by using the Open... item in the File menu (or the Open icon). The TalairachBrain.vmr file is also loaded automatically when using the glass brain visualization tool. | brodmann partition scheme, cerebral cortex, human, brain, talairach | has parent organization: BrainVoyager | nlx_144323 | SCR_008800 | 2026-09-05 06:26:28 | 0 | |||||||||
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MUSC Health Podcast Library Resource Report Resource Website |
MUSC Health Podcast Library (RRID:SCR_008827) | MUSC Health Podcast Library, MUSC Podcast | data or information resource, narrative resource, podcast | The MUSChealth.com Podcast Library, featuring podcasts on a variety of topics related to your health and our services here at MUSC. These medical podcasts are hosted by MUSC faculty, physicians and special guests and are produced and directed by Linda Austin, M.D. Current topics include: * Academics and Education * Aging, Geriatrics and Caregiving * Alcohol and Drug Dependency * Allergies and Asthma * Ashley River Tower * Bones, Joints, Muscles and Spine * Cancer * Children''s Health * Cosmetic Surgery * Dental * Dermatology/Skin Problems * Diabetes, Endocrinology and Metabolism * Digestive Health * ENT: Ear, Nose and Throat * Executive Health * Eye Health * General Health and Wellness * Heart and Vascular Health * Hospice * Kohl''s Take a Minute for Kids * Lungs and Breathing * Men''s Health * Mental Health * MUSC News and Events * Neurological Health * Organ Transplant * Osteoporosis * Pregnancy - Week by Week * Pregnancy and Childbirth * Radiology * Research and Clinical Trials * SC Health, Leadership and Policy * Sports Medicine * Stroke * Urology * Weight Loss Surgery Follow-up * Weight Management * Women''s Health | health, medical, academic, education, geriatrics, caregiving, alcohol addiction, drug dependency, allergy, asthma, bone, joint, muscle, spine, cancer, child, cosmetic surgery, tooth, dermatology, skin, diabetes, endocrinology, metabolism, digestive system, ear, nose, throat, eye, heart, vascular system, hospice, child, lung, breathing, man, mental health, neurology, organ transplant, osteoporosis, pregnancy, childbirth, radiology, research, clinical trial, leadership, policy, sports medicine, stroke, urology, weight loss, surgery, weight management, woman, human | has parent organization: Medical University of South Carolina; South Carolina; USA | Aging | nlx_144507 | SCR_008827 | MUSC Health Audio Podcasts, MUSChealth.com Podcast Library | 2026-09-05 06:26:29 | 0 | |||||||
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Central Brain Tumor Registry of the United States Resource Report Resource Website 10+ mentions |
Central Brain Tumor Registry of the United States (RRID:SCR_008748) | CBTRUS | nonprofit organization | Voluntary, non-profit organization dedicated to collecting and disseminating statistical data. Resource for gathering and disseminating epidemiologic data on all primary benign and malignant brain and other CNS tumors. | human, brain, tumor, cancer, central nervous system, epidemiology, incidence, survival, diagnosis, treatment, benign, malignant, registry, epidemiological data, aggregator, clinical, statistics, population, histology, age, gender, race, hispanic, mortality | Brain tumor, Aging | American Brain Tumor Association ; National Brain Tumor Society ; Pediatric Brain Tumor Foundation ; NCI contract HHSN261201000576P |
PMID:23095881 | Application required., The community can contribute to this resource | grid.492337.8, ISNI: 0000 0004 0484 2205, nlx_143889 | https://ror.org/03849s113 | SCR_008748 | 2026-09-05 06:26:27 | 26 | |||||
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Brain Observatory Resource Report Resource Website |
Brain Observatory (RRID:SCR_010641) | Brain Observatory | biospecimen repository, data or information resource, material storage repository, portal, service resource, storage service resource, topical portal, video resource | Formerly a topical portal studying the brain which collected and imaged 1000 human brains, the Brain Observatory has partnered with the Institute for Brain and Society to build virtual laboratories that will feed directly into the database of images and knowledge created in the context of the Human Brain Library. The Brain Observatory will also host exhibits, conferences, and events aimed at promoting a heightened awareness of brain research and how its results can benefit personal brain fitness and mental health. | human, brain, visual cortex, neuroimaging | has parent organization: University of California San Diego School of Medicine; California; USA | Human immunodeficiency virus, NeuroAIDS, AIDS, Amnesia | NIMH ; NSF ; The Dana Foundation ; NEI |
Public | nlx_69083 | http://thebrainobservatory.ucsd.edu/ | SCR_010641 | The Brain Observatory | 2026-09-05 06:26:44 | 0 | ||||
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DFLAT Resource Report Resource Website 1+ mentions |
DFLAT (RRID:SCR_010738) | DFLAT | data or information resource, data set, narrative resource, standard specification | We are an interdisciplinary team dedicated to annotating gene function related to human fetal development. We are contributing new functional annotation to the Gene Ontology, curating and mining gene sets suitable for the interpretation of developmental genomic data, and creating the computational tools needed to apply genomics for better understanding the molecular mechanisms of human development. Our GO annotation is in the process of being incorporated into the GOA public release. The GONE (Gene Ontology Non-Eligible) database is where we store annotations relevant to our research but that don''t quite meet GOA''s standards. Usually an annotation falls into this category because either the gene/protein described is a family of genes/proteins rather than a specific one, there is no UniProt ID to identify the gene/protein in the system, a GO term does not yet exist to describe the particular function, process, or location of the gene/protein, the species is not clearly identifiable in the paper, or the evidence is not as reliable (GO evidence codes TAS and NAS). As individual annotations these are more suspect than current GO annotation. However, for functional analysis of expression data, these gene sets can be valuable even with a certain amount of noise. We also include here a link to the supplementary data from our forthcoming PSB 2011 paper on gene set mining. | human, fetal, development | has parent organization: Tufts University; Massachusetts; USA | NICHD R01 HD058880 | PMID:21121032 | nlx_95610 | SCR_010738 | Developmental FunctionaL Annotation at Tufts | 2026-09-05 06:26:45 | 2 | ||||||
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BWA Resource Report Resource Website 1000+ mentions |
BWA (RRID:SCR_010910) | BWA | alignment software, data analysis software, data processing software, image analysis software, sequence analysis software, software application, software resource | Software for aligning sequencing reads against large reference genome. Consists of three algorithms: BWA-backtrack, BWA-SW and BWA-MEM. First for sequence reads up to 100bp, and other two for longer sequences ranged from 70bp to 1Mbp. | sequence, alignment, reference, genome, human, short, long, read, bio.tools |
is listed by: OMICtools is listed by: bio.tools is listed by: Debian is listed by: SoftCite is related to: shovill is related to: Proovread is related to: BWA-MEM2 has parent organization: SourceForge is required by: RelocaTE |
PMID:19451168 PMID:20080505 DOI:10.1093/bioinformatics/btp324 |
Free, Available for download, Freely available | SCR_015853, biotools:bwa-sw, OMICS_00654 | https://sourceforge.net/projects/bio-bwa/files/, https://bio.tools/bwa-sw, https://sources.debian.org/src/bwa/ | SCR_010910 | Burrows-Wheeler Aligner (BWA), Burrows-Wheeler Aligner | 2026-09-05 06:26:50 | 2638 | |||||
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Talairach Daemon Resource Report Resource Website 100+ mentions |
Talairach Daemon (RRID:SCR_000448) | talairach.org | atlas, data or information resource, database, software application, software resource | Software automated coordinate based system to retrieve brain labels from the 1988 Talairach Atlas. Talairach Daemon database contains anatomical names for brain areas using x-y-z coordinates defined by the 1988 Talairach Atlas. | anatomical structure, atlas, fmri, pet, activation foci, cognition, talairach, human, brain, brain mapping, atlas application, database application, atlas application, database application, java, magnetic resonance, os independent, label, probability map, FASEB list |
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) is listed by: Biositemaps is related to: WFU PickAtlas has parent organization: University of Texas Health Science Center at San Antonio; Texas; USA |
EJLB Foundation ; Human Brain Project |
PMID:10912591 | Free, Available for download, Freely available | nif-0000-00042 | http://www.nitrc.org/projects/tal-daemon | SCR_000448 | Talairach Software | 2026-09-05 06:24:19 | 383 | ||||
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Pediatric Brain Tumor Consortium Resource Report Resource Website 1+ mentions |
Pediatric Brain Tumor Consortium (RRID:SCR_000658) | PBTC | consortium, data or information resource, organization portal, portal | The PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) is a multidisciplinary cooperative research organization devoted to the study of correlative tumor biology and new therapies for primary CNS tumors of childhood. PBTC's mission is to contribute rapidly and effectively to the understanding and cure of these tumors through the conduct of multi-center, multidisciplinary, innovative studies with designs and analyses based on uniformly high quality statistical science. While the primary mission of the PBTC is to identify through laboratory and clinical science superior treatment strategies for children with brain cancers, the PBTC investigators recognize their profound responsibility to meet the special needs of the children and families as they face this enormous challenge. Members are committed to working within their institutions and communities to improve support services and follow up care for these patients and their families. The PBTC's primary objective is to rapidly conduct novel phase I and II clinical evaluations of new therapeutic drugs, new biological therapies, treatment delivery technologies and radiation treatment strategies in children from infancy to 21 years of age with primary central nervous system (CNS) tumors. A second objective is to characterize reliable markers and predictors (direct or surrogate) of brain tumors' responses to new therapies. The Consortium conducts research on brain tumor specimens in the laboratory to further understand the biology of pediatric brain tumors. A third objective is to develop and coordinate innovative neuro-imaging techniques. Through the PBTC's Neuro-Imaging Center, formed in May 2000, research to evaluate new treatment response criteria and neuro-imaging methods to understand regional brain effects is in progress. These imaging techniques can also advance understanding of significant neuro-toxicity in a developing child's central nervous system. The Neuro-Imaging Center is supported in part by private sources - grants from foundations and non-profit organizations - in addition to the NCI. As an NCI funded Consortium, the Pediatric Brain Tumor Consortium (PBTC) is required to make research data available to other investigators for use in research projects. An investigator who wishes to use individual patient data from one or more of the Consortium's completed and published studies must submit in writing a description of the research project, the PBTC studies from which data are requested, the specific data requested, and a list of investigators involved with the project and their affiliated research institutions. A copy of the requesting investigator's CV must also be provided. Participating Institutions: Children's Hospital of Philadelphia, Children's National Medical Center (Washington, DC), Children's Memorial Hospital (Chicago), Duke University, National Cancer Institute, St. Jude Children's Research Hospital, Texas Children's Cancer Center, University of California at San Francisco, and University of Pittsburgh. | human, child, pediatric, brain, tumor, cancer, brain cancer, central nervous system, imaging | NCI | grid.477819.4, nlx_143885 | https://ror.org/00hj21c17 | SCR_000658 | 2026-09-05 06:24:23 | 1 | ||||||||
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Colour and Vision Research Laboratory Resource Report Resource Website |
Colour and Vision Research Laboratory (RRID:SCR_000770) | data or information resource, laboratory portal, organization portal, portal | The Colour & Vision Research laboratory and database are based at the Institute of Ophthalmology, which is part of University College London. The Institute and CVRL are both closely associated with Moorfields Eye Hospital. The Institute is next door to Moorfields Eye Hospital near Old Street tube station (see directions). At the Colour & Vision Research laboratory, we investigate normal and clinical human visual perception. Our research focuses on questions about colour perception, light and dark adaptation, night-time vision, and the temporal and spatial properties of vision. Our primary goal is to understand the nature of the mechanisms that underlie visual perception, and to understand how those mechanism malfunction in clinical cases. More details about our research can be found by looking at the publications of members of the laboratory. The CVRL database, first set up in 1995, provides an annotated library of downloadable standard data sets relevant to colour and vision research. The focus of this site is primarily scientific and technical, but some introductory background information is also provided. A consistent set of functions for modeling colour vision based on the Stockman & Sharpe cone fundamentals and on our more recent luminous efficiency measurements are summarized under the category CVRL functions. These functions are tabulated in 0.1, 1 and 5 nm steps and can be returned as csv, xml, or tabular data or as dynamic plots. The Stockman & Sharpe cone fundamentals are the basis of a CIE proposal for physiologically-relevant colour matching functions. These functions, which are indentical to the CVRL functions, are summarized under the category CIE 2007 functions. The CIE functions are also tabulated in 0.1, 1 and 5 nm steps, and can also be returned as csv, xml, or tabular data or as dynamic plots. Significant additions to the database are the individual colour matching measurements made by Stiles & Burch. These have been compiled and cross-checked with the help of Boris Oicherman, Alexander Logvinenko, and Abhijit Sarkar from hard copies of the original data provided by Pat Trezona and Mike Webster. They can be obtained as Excel files and are available for both 2 and 10 colour matches. Other data sets, which are provided as csv files, include cone fundamentals, colour matching functions, chromaticity coordinates, prereceptoral filter density spectra, photopigment spectra, and CIE standards. Many of these data sets can also be viewed as dynamic plots. Sponsors: CVRL is funded by BBSRC The Wellcome Trust, Fight for Sight, National Eye Institute, and NIH. | chromaticity, clinical, color, human, ophthalmology, perception, photopigment, research, spectra, temporal, vision, visual | has parent organization: University College London; London; United Kingdom | nif-0000-24691 | SCR_000770 | CVRL | 2026-09-05 06:24:25 | 0 | |||||||||
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Yandell Lab Portal Resource Report Resource Website |
Yandell Lab Portal (RRID:SCR_000807) | data analysis software, data or information resource, data processing software, laboratory portal, organization portal, portal, software application, software resource | Sequenced genomes contain a treasure trove of information about how genes function and evolve. Getting at this information, however, is challenging and requires novel approaches that combine computer science and experimental molecular biology. My lab works at the intersection of both domains, and research in our group can be summarized as follows: generate hypotheses concerning gene function and evolution by computational means, and then test these hypotheses at the bench. This is easier said than done, as serious barriers still exist to using sequenced genomes and their annotations as starting points for experimental work. Some of these barriers lie in the computational domain, others in the experimental. Though challenging, overcoming these barriers offers exciting training opportunities in both computer science and molecular genetics, especially for those seeking a future at the intersection of both fields. Ongoing projects in the lab are centered on genome annotation and comparative genomics; exploring the relationships between sequence variation and human disease; and high-throughput biological image analysis. Current software tools available: VAAST (the Variant Annotation, Analysis & Search Tool) is a probabilistic search tool for identifying damaged genes and their disease-causing variants in personal genome sequences. VAAST builds upon existing amino acid substitution (AAS) and aggregative approaches to variant prioritization, combining elements of both into a single unified likelihood-framework that allows users to identify damaged genes and deleterious variants with greater accuracy, and in an easy-to-use fashion. VAAST can score both coding and non-coding variants, evaluating the cumulative impact of both types of variants simultaneously. VAAST can identify rare variants causing rare genetic diseases, and it can also use both rare and common variants to identify genes responsible for common diseases. VAAST thus has a much greater scope of use than any existing methodology. MAKER 2 (updated 01-16-2012) MAKER is a portable and easily configurable genome annotation pipeline. It's purpose is to allow smaller eukaryotic and prokaryotic genomeprojects to independently annotate their genomes and to create genome databases. MAKER identifies repeats, aligns ESTs and proteins to a genome, produces ab-initio gene predictions and automatically synthesizes these data into gene annotations having evidence-based quality values. MAKER is also easily trainable: outputs of preliminary runs can be used to automatically retrain its gene prediction algorithm, producing higher quality gene-models on seusequent runs. MAKER's inputs are minimal and its ouputs can be directly loaded into a GMOD database. They can also be viewed in the Apollo genome browser; this feature of MAKER provides an easy means to annotate, view and edit individual contigs and BACs without the overhead of a database. MAKER should prove especially useful for emerging model organism projects with minimal bioinformatics expertise and computer resources. RepeatRunner RepeatRunner is a CGL-based program that integrates RepeatMasker with BLASTX to provide a comprehensive means of identifying repetitive elements. Because RepeatMasker identifies repeats by means of similarity to a nucleotide library of known repeats, it often fails to identify highly divergent repeats and divergent portions of repeats, especially near repeat edges. To remedy this problem, RepeatRunner uses BLASTX to search a database of repeat encoded proteins (reverse transcriptases, gag, env, etc...). Because protein homologies can be detected across larger phylogenetic distances than nucleotide similarities, this BLASTX search allows RepeatRunner to identify divergent protein coding portions of retro-elements and retro-viruses not detected by RepeatMasker. RepeatRunner merges its BLASTX and RepeatMasker results to produce a single, comprehensive XML-based output. It also masks the input sequence appropriately. In practice RepeatRunner has been shown to greatly improve the efficacy of repeat identifcation. RepeatRunner can also be used in conjunction with PILER-DF - a program designed to identify novel repeats - and RepeatMasker to produce a comprehensive system for repeat identification, characterization, and masking in the newly sequenced genomes. CGL CGL is a software library designed to facilitate the use of genome annotations as substrates for computation and experimentation; we call it CGL, an acronym for Comparitive Genomics Library, and pronounce it Seagull. The purpose of CGL is to provide an informatics infrastructure for a laboratory, department, or research institute engaged in the large-scale analysis of genomes and their annotations. | software, gene, genome annotation, human |
has parent organization: University of Utah; Utah; USA is parent organization of: VAAST |
PMID:21700766 PMID:21700266 PMID:21325948 PMID:21347285 |
nlx_144364 | SCR_000807 | 2026-09-05 06:24:26 | 0 | |||||||||
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Functional Annotation of the Mammalian Genome Resource Report Resource Website 10+ mentions |
Functional Annotation of the Mammalian Genome (RRID:SCR_000788) | FANTOM | consortium, data or information resource, database, organization portal, portal | International collaborative research project and database of annotated mammalian genome. Used to improve estimates of total number of genes and their alternative transcript isoforms in both human and mouse. Consortium to assign functional annotations to full length cDNAs that were collected during Mouse Encyclopedia Project at RIKEN. | mammal, genome, isoform, human, gene, transcriptome, regulatory network, FASEB list |
is related to: CAGE Basic Viewer for Mus musculus is related to: RIKEN integrated database of mammals has parent organization: RIKEN Brain Science Institute |
NIMH MH062261 | PMID:20211142 PMID:33211864 |
nif-0000-30552 | http://fantom.gsc.riken.jp | SCR_000788 | Functional Annotation of the Mammalian Genome, FANTOM, Functional Annotation of the Mammalian Genome (FANTOM) | 2026-09-05 06:24:27 | 43 | |||||
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NeuroMouse Database Resource Report Resource Website |
NeuroMouse Database (RRID:SCR_001143) | NeuroMouse | atlas, data or information resource, data repository, database, service resource, storage service resource | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 17, 2023.Toolbook(tm) based, interactive graphical database which provides structural, molecular, and genetic information on the adult murine nervous system; and its relevance to human neurobiology. This resource is primarily designed as a platform for users to interact, each sharing knowledge on their own area of expertise, which is compiled to a master database. This hypertext atlas presently comprises more than 1000 pages and is designed to provide a flexible integrated resource for the description and discussion of all forms mammalian neurologic data. Version 4.0 of the NeuroMouse program extends the program's basic framework to include a number of areas in modern molecular neurobiology. This system provides an integrated resource for the characterization and description of mammalian neurological data. Major divisions include: Neural Atlas, Molecular Atlas, Genetics/Surgical Lesion Atlas. Neuromouse has been integrated into our strain-specific three dimensional MRI and surgical atlases of the murine CNS. Database contents: Neural Atlas: - Rotational representation of the murine brain. - Neural structures: visual and alphabetic point and click index of neural structures, pathways and systems. - Brain atlas:photographic serial sections in the coronal, sagittal, and horizontal planes (average plate distance - 300 um). Physical brain distances are also provided as are meta-index grids to allow rapid movement between different planes and regions. # Catalog of primary and immortalized neural cells indexed to relevant neural structures. Molecular Atlas: - Index of neurotransmitters: Acetylcholine, GABA, Glutamate, Aspartate, Glycine, Dopamine, Norepinephrine, Epinephrine, Serotonin (synthesis, distribution, degradation, molecular modules, receptors, subunits, agonists, antagonists, gene structure, localization, physical properties and transgenics are indicated for each item). - Index of neurotrophins / neurokines: NGF, BDNF, NT-3, NT-4/5, CNTF, LIF, Onostain M, IL-6, GDNF, FGF's, S100b (ligand, receptors, expression pattern, physical properties, homologous factors, transgenics/knockouts, chromosomal location, effects of agent, and effects of factors on agent are indicated for each item). - Index of additional neural agents: Bcl-2, TNF/Fas, TGF-beta, P53/Rb, PDGF, EGF family (ligand, receptor, expression patterns, physical properties, homologous factors, transgenics/ knockouts, chromosomal location, effects of agent, effects of factors on agent are indicated for each item). - Molecular biology: Molecular biology of important neural genes with integrated l links, plus selected neural topics (ex. programmed cell death, inducible gene systems, protein motifs, neural gene elements, and selected signal transduction pathways). Genetics Atlas: - Lesion paradigms: Index of common neuronal structural and chemical lesion paradigms. - Selected procedures: description of common neurosurgical, cell tracing, culturing and laboratory procedures. - Neurologic syndromes: Index of important human neurologic syndromes and appropriate animals models. - Neural mutant database: Index and description of naturally occurring and genetically modified murine neurologic mutations; including pages on double knockout animals. Interactive maps of each murine chromosome and human syntenic maps. | epinephrine, gaba, acetylcholine, agonist, antagonist, aspartate, dopamine, glutamate, glycine, human, molecular biology, murine chromosome, mutant, neural, neural factor, neurokine, neurological, neurotransmitter, n eurotrophin, norepinephrine, serotonin, molecular neuroanatomy resource, nervous system, adult, murine | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-11000 | SCR_001143 | 2026-09-05 06:24:30 | 0 | |||||||||
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Brain Dynamics Centre Resource Report Resource Website |
Brain Dynamics Centre (RRID:SCR_001685) | data or information resource, database, portal, topical portal | The Brain Dynamics Centre (BDC) is a network of centers and units. It achieves a unique exploration of the healthy brain and disorders of brain function. It translates these insights into new ways to tailor treatments to the individual. There approach is: "integrative neuroscience" - bringing together clinical observations, theory, and modern imaging technologies. And it's theoretical framework derives from linking physiology, psychology and evolution. Additionally, BDC also actively researches ADHD and conduct disorder, stress and trauma-related problems, depression and anxiety, anorexia nervosa, psychosis (including early onset) and conversion disorders. The research facilities DBC include assessment, rooms, two cognition-brain function laboratories, genotyping and an MRI Suite with 1.5 and 3T GE systems. BDC is the coordinating site for an international network - BRAINnet. It has over 180 members, and coordinates access to the first standardized database on the human brain for scientific purposes: Brain Resource International Database. | evolution, function, genetics, adhd, anorexia nervosa, anxiety, behavior, brain, brain disorder, brain imaging, clinical, cognition, conduct disorder, conservation disorder, database, depression, disorder, genotyping, healthy, human, keywords: brain, laboratory, mental illness, mri, neuroscience, onset, physiology, post traumatic stress disorder (ptsd), psychology, psychosis, research, stress, technology, trauma, treatment | Free, Freely Available | nif-0000-10177 | SCR_001685 | BDC | 2026-09-05 06:24:37 | 0 | |||||||||
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George Mason University: Krasnow Institute for Advanced Study Resource Report Resource Website |
George Mason University: Krasnow Institute for Advanced Study (RRID:SCR_001741) | data or information resource, organization portal, portal, postdoctoral program resource, training resource | The Krasnow Institute seeks to expand understanding of mind, brain, and intelligence by conducting research at the intersection of the separate fields of cognitive psychology, neurobiology, and the computer-driven study of artificial intelligence and complex adaptive systems. These separate disciplines increasingly overlap and promise progressively deeper insight into human thought processes. The Institute also examines how new insights from cognitive science research can be applied for human benefit in the areas of mental health, neurological disease, education, and computer design. It is this informed access to mind and brain that is the core of the mission of The Krasnow Institute. While their goals and tools are scientific, they also are fully cognizant of the applications of the results for the benefit of mankind, in areas like mental health, neurological diseases, and computer design. In asking the major questions they realized the necessity of being flexible, innovative, and trans-disciplinary. Therefore, they became dedicated to bringing together scholars from a wide variety of specialties and providing a milieu where they can be both productive and interactive. This institute will provide these researchers with the tools required to move ahead and create an environment of optimal scientific integrity coupling innovation with risk taking. The Krasnow institute is especially attuned to the deep insights from evolutionary biology, which is at the root of understanding all organismic functions including cognition; computer studies of complex systems, which present a revolution in our ability to deal with the world of interactive agents; and a long history of cognitive psychology, which provides a huge data base of human abilities and responses. It also continues to develop its long-term research program based on the contributions of George Mason University faculty holding joint appointments at Krasnow and other GMU academic departments. Additionally, the Krasnow Institute Department of Molecular Neuroscience, together with the College of Science (COS) and the College of Humanities and Social Sciences (CHSS), oversees the campus-wide Neuroscience Council in developing the Neuroscience PhD curriculum. Research groups in the Krasnow institute include: - Adaptive Systems Laboratory - Center for Neural Dynamics - Center for Social Complexity - Center for the Study of Neuroeconomics o Neuroeconomics Laboratory - Comparative Vertebrate Neurobiology Research Group - Center for Neuroinformatics, Neural Structures, and Neuroplasticity (CN3) o Computational and Experimental Neuroplasticity (CENlab) o Computational Neuroanatomy Group o Physiological and Behavioral Neuroscience in Juveniles (PBNJ) Lab - Receptor Complexes and Signaling Lab - Krasnow Investigations of Developmental Learning and Behavior (KIDLAB) - Neuro Imaging Core of the Krasnow Institute | dynamics, education, emotion, evolutionary, function, adaptive, artificial, behavior, behavioral, biology, biomedical, brain, cognition, cognitive, cognitive science, complex, computational, computer, design, disease, happiness, homo sapiens, human, imaging, intelligence, learning, mental health, mind, nature, neural, neuroanatomy, neurobiology, neuroeconomics, neuroinformatics, neurological, neuroplasticity, organismic, physiological, psychology, receptor, research, signaling, social, structure, system, theological, thought, vertebrate |
has parent organization: George Mason University; Virginia; USA is parent organization of: BraVa is parent organization of: Computational Neuroanatomy Group |
Free, Freely Available | nif-0000-10239 | SCR_001741 | GMU Kransnow | 2026-09-05 06:24:38 | 0 |
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