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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
National Genome Research Network
 
Resource Report
Resource Website
10+ mentions
National Genome Research Network (RRID:SCR_006626) NGFN data or information resource, organization portal, portal The program of medical genome research is a large-scale biomedical research project which extends the national genome research net (NGFN) and will be funded by the federal ministry of education and research (BMBF) from 2008-2013. Currently the program includes two fields: * Research ** NGFN-Plus: With the aim on combating diseases that are central to health policy, several hundred researchers are systematically investigating the complex molecular interactions of the human body. They are organized in 26 Integrated Genome Research Networks. * Application ** NGFN-Transfer: The rapid transfer of results from medical genome research into medical and industrial application is the aim of the scientists from research institutes and biomedical enterprises that cooperate in eight Innovation Alliances. AREAS OF DISEASE * Cardiovascular disease * Cancer * Neuronal diseases * Infections and Inflammations * Environmental factors genome, research, gene, disease Cardiovascular disease, Cancer, Neuronal disease, Infectious disease, Inflammation, Disease linked to environment BMBF nlx_151595 SCR_006626 NGFN - National Genome Research Network, German National Genome Research Network 2026-09-12 01:00:57 26
WebApollo: A Web-Based Sequence Annotation Editor for Community Annotation
 
Resource Report
Resource Website
10+ mentions
WebApollo: A Web-Based Sequence Annotation Editor for Community Annotation (RRID:SCR_005321) WebApollo production service resource, service resource, software resource, source code WebApollo is an extensible web-based sequence annotation editor for community annotation. No software download is required and the annotations are saved to a centralized database with real-time annotation updating. (The edit server mediates annotation changes made by multiple users.) The Web based client uses JBrowse, is fast and highly interactive. WebApollo accesses many types of genomic data including access to public data from UCSC, Ensembl, and GMOD Chado databases. Source code (BSD License) * Client source code: https://github.com/berkeleybop/jbrowse * Annotation editing engine: http://code.google.com/p/apollo-web * Data model and I/O layer: http://code.google.com/p/gbol * Trellis server code: http://code.google.com/p/genomancer sequence, annotation, genome has parent organization: Lawrence Berkeley National Laboratory
has parent organization: University of California at Berkeley; Berkeley; USA
has parent organization: Georgetown University; Washington D.C.; USA
nlx_144381 SCR_005321 WebApollo - A Web-Based Sequence Annotation Editor for Community Annotation 2026-09-12 01:00:56 13
CLC Main Workbench
 
Resource Report
Resource Website
10+ mentions
CLC Main Workbench (RRID:SCR_000354) CLC Main Workbench software resource, software toolkit A suite of software for DNA, RNA and protein sequence data analysis. The software allows for the analysis and visualization of Sanger sequencing data as well as gene expression analysis, molecular cloning, primer design, phylogenetic analyses, and sequence data management. sequencing, analysis, cloning, data, management, molecular, gene, genome, dna, rna is listed by: OMICtools
is listed by: SoftCite
Restricted OMICS_01813 SCR_000354 2026-09-12 01:02:23 31
GeSeq
 
Resource Report
Resource Website
500+ mentions
GeSeq (RRID:SCR_017336) data processing software, service resource, software application, software resource Software tool for rapid and accurate annotation of organelle genomes, in particular chloroplast genomes. rapid, accurate, annotation, organelle, genome, chloroplast, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
German Science Foundation ;
Human Frontier Science Program ;
Max Planck Society
PMID:28486635 Free, Freely available biotools:geseq https://bio.tools/geseq SCR_017336 2026-09-12 01:01:05 535
seq-annot
 
Resource Report
Resource Website
1+ mentions
seq-annot (RRID:SCR_018731) software application, software resource, software toolkit, standalone software Software Python package for annotating and counting genomic features in genomes and metagenomes. Software tools to facilitate annotation and comparison of genomes and metagenomes. Annotating, counting, comparison, genomic feature, genome, metagenome, metagenomics, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:seq-annot https://bio.tools/seq-annot SCR_018731 2026-09-12 01:01:07 1
TransDecoder
 
Resource Report
Resource Website
1000+ mentions
TransDecoder (RRID:SCR_017647) data processing software, software application, software resource, standalone software Software tool to identify candidate coding regions within transcript sequences, such as those generated by de novo RNA-Seq transcript assembly using Trinity, or constructed based on RNA-Seq alignments to genome using Tophat and Cufflinks.Starts from FASTA or GFF file. Can scan and retain open reading frames (ORFs) for homology to known proteins by using BlastP or Pfam search and incorporate results into obtained selection. Predictions can then be visualized by using genome browser such as IGV. Identify, candidate, coding, region, transcript, sequence, de novo, RNAseq, assembly, alignment, genome, open, reading, frame, homology, protein, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:transDecoder, OMICS_10852 https://bio.tools/TransDecoder, https://sources.debian.org/src/transdecoder/, https://github.com/TransDecoder/TransDecoder/wiki SCR_017647 , Find Coding Regions Within Transcripts 2026-09-12 01:01:06 1572
LACHESIS
 
Resource Report
Resource Website
50+ mentions
LACHESIS (RRID:SCR_017644) data processing software, software application, software resource Software tool for chromosome scale scaffolding of de novo genome assemblies based on chromatin interactions.Method exploits signal of genomic proximity in Hi-C datasets for ultra long range scaffolding of de novo genome assemblies. Chromosome, scale, scaffolding, de novo, genome, assembly, chromatin, Hi-C, data, clustering, contig National Science Foundation ;
NHGRI HG006283;
NHGRI T32 HG000035
PMID:24185095 Free, Available for download, Freely available SCR_017644 Ligating Adjacent Chromatin Enables Scaffolding In Situ 2026-09-12 01:01:06 70
Purge_haplotigs
 
Resource Report
Resource Website
10+ mentions
Purge_haplotigs (RRID:SCR_017616) data processing software, software application, software resource Pipeline for reassigning primary contigs that should be labelled as haplotigs. Used for third generation sequencing based assemblies to automate reassignment of allelic contigs, and to assist in manual curation of genome assemblies. Reassigning, primary, contig, label, haplotig, third, generation, sequencing, assembly, allelic, curation, genome, alignment PMID:30497373 Free, Available for download, Freely available SCR_017616 2026-09-12 01:01:06 14
Recognition of Errors in Assemblies using Paired Reads
 
Resource Report
Resource Website
1+ mentions
Recognition of Errors in Assemblies using Paired Reads (RRID:SCR_017625) REAPR data processing software, software application, software resource Software tool to identify errors in genome assemblies without need for reference sequence. Can be used in any stage of assembly pipeline to automatically break incorrect scaffolds and flag other errors in assembly for manual inspection. Reports mis-assemblies and other warnings, and produces new broken assembly based on error calls. Identify, error, genome, assembly, without, reference, sequence, incorrect, scaffold, error is listed by: Debian
is listed by: OMICtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
European Union ;
JSPS KAKENHI ;
Wellcome Trust
PMID:23710727 Free, Available for download, Freely available OMICS_04068 https://sources.debian.org/src/reapr/ SCR_017625 2026-09-12 01:01:06 2
JTK_CYCLE
 
Resource Report
Resource Website
1+ mentions
JTK_CYCLE (RRID:SCR_017962) data processing software, software application, software resource Software R package for Detecting Rhythmic Components in Genome-Scale Data Sets. Non-parametric algorithm to identify rhythmic components in large datasets. Identifies and characterizes cycling variables in large datasets. Washington University in St.Louis, detecting rhythmic, component, genome, scale, dataset, algorithm, non parametric, cycling, variable NHBLI R01 HL097800;
NIMH P50 MH074924;
Pennsylvania Commonwealth Health Research Formula Funds
PMID:20876817 Free, Freely available SCR_017962 Jonckheere-Terpstra-Kendall-CYCLE 2026-09-12 01:01:06 5
GeneSyntenyPipeline
 
Resource Report
Resource Website
GeneSyntenyPipeline (RRID:SCR_018198) data processing software, software application, software resource Software pipeline was designed to draw gene synteny plot between genomes and obtain 1 to 1 gene pairs from each genome. Genome, synteny, plot, JCVI, gene pair, data Free, Available for download, Freely available SCR_018198 2026-09-12 01:01:07 0
CustomCDF
 
Resource Report
Resource Website
1+ mentions
CustomCDF (RRID:SCR_018527) data processing software, software application, software resource Brainarray custom CDFs for processing raw Affymetrix data. Used to map probe to probesets. Oligonucleotide probes on GeneChips are reorganized based on latest genome and transcriptome information. Brainarray, custom CDF, processing raw Affymetrix data, data processing, map probe, probset, oligonucleotide probe, GeneChips, genome, transcriptome, data PMID:16284200 Free, Freely available https://gist.github.com/rmflight/3108891, https://rdrr.io/github/jakejh/metapredict/man/installCustomCdfPackages.html SCR_018527 2026-09-12 01:01:07 8
iPiG
 
Resource Report
Resource Website
iPiG (RRID:SCR_016164) iPiG software application, software resource, standalone software Standalone software tool for the integration of peptide identifications from mass spectrometry experiments into existing genome browser visualizations. integration, peptide, spectrum, match, genome, browser, visualization, experiment, pms, ms, bio.tools uses: UCSC Genome Browser
is listed by: bio.tools
is listed by: Debian
Robert Koch-Institute PMID:23226516
DOI:10.1371/journal.pone.0050246
Free, Available for download biotools:ipig, OMICS_06913 https://bio.tools/ipig, https://sources.debian.org/src/ipig/ SCR_016164 iPiG: Integrating Peptide Spectrum Matches Into Genome Browser Visualizations 2026-09-12 01:02:53 0
Chromosome Scale Assembler
 
Resource Report
Resource Website
1+ mentions
Chromosome Scale Assembler (RRID:SCR_017960) CSA software application, software resource Software pipeline for high-throughput chromosome level vertebrate genome assembly. Pipeline, which after contig assembly performs post assembly improvements by ordering assembly and closing gaps, as well as splitting of low supported regions. Assembly, chromosome, vertebrate, genome, contig, closing, gap, splitting, low, supported, region, bio.tools is listed by: bio.tools
is listed by: Debian
German Research foundation Free, Available for download, Freely available biotools:csa2.6 https://bio.tools/CSA2.6 SCR_017960 Chromosome Scale Assembler 2026-09-12 01:02:55 5
ProtHint
 
Resource Report
Resource Website
50+ mentions
ProtHint (RRID:SCR_021167) software resource, software toolkit Software pipeline for predicting and scoring hints (in form of introns, start and stop codons) in genome of interest by mapping and spliced aligning predicted genes to database of reference protein sequences. Predicting and scoring hints, form of introns, start and stop codons, genome, mapping, spliced aligning, predicted genes, database, reference protein sequences has parent organization: Georgia Institute of Technology; Georgia; USA Free, Available for download, Freely available SCR_021167 2026-09-12 01:02:58 51
BlobTools2
 
Resource Report
Resource Website
100+ mentions
BlobTools2 (RRID:SCR_023351) data analysis software, data processing software, software application, software resource Software suite for identifying and isolating non-target data in draft and publicly available genome assemblies. Used to process assembly, read and analysis files for fully reproducible interactive exploration in browser-based Viewer. Used for interactive quality assessment of genome assemblies .BlobTools2 is reimplementation of BlobTools, written in Python 3 with fully modular design to make creating new datasets and adding additional analysis types easier. interactive quality assessment, genome assemblies, identifying and isolating non-target data, genome, QC, filtering, process assembly, read and analysis files, is related to: Blobtools
is related to: Blobtoolkit
BBSRC Bioinformatics and Biological Resources fund PMID:32071071 Free, Available for download, Freely available https://github.com/blobtoolkit/blobtoolkit SCR_023351 blobtoolkit 2026-09-12 01:00:38 383
SPAdes
 
Resource Report
Resource Website
100+ mentions
SPAdes (RRID:SCR_000131) SPAdes software resource, software toolkit Software package for assembling single cell genomes and mini metagenomes. Uses short read sets as input. Used for genomes of uncultivatable bacteria that vastly exceeds what may be obtained via traditional metagenomics studies. Works with Illumina or IonTorrent reads and can provide hybrid assemblies using PacBio, Oxford Nanopore and Sanger reads. Intended for small genomes like bacterial or fungal., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. assembler, single, cell, small, genome, short, read, data is used by: shovill
is listed by: OMICtools
is listed by: Debian
is listed by: SoftCite
is related to: rnaSPAdes
is related to: rnaQUAST
has parent organization: Saint Petersburg Academic University; Saint Petersburg; Russia
works with: Illumina: iSeq 100 Sequencing System
Government of the Russian Federation ;
NCRR P41 RR024851
PMID:24093227
PMID:22506599
DOI:10.1089/cmb.2012.0021
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01502 https://sources.debian.org/src/spades/ http://bioinf.spbau.ru/spades/ SCR_000131 SPAdes Genome Assembler 2026-09-12 01:00:51 108
variation graph
 
Resource Report
Resource Website
variation graph (RRID:SCR_024369) vg software resource, software toolkit Software toolkit to improve read mapping by representing genetic variation in reference.Provides succinct encoding of sequences of many genomes. read mapping, representing genetic variation in reference, encoding of sequences, genome is listed by: Debian PMID:30125266 Free, Available for download, Freely available, https://sources.debian.org/src/vg/ SCR_024369 variationgraph 2026-09-12 01:01:17 0
Non-Human Genome Segmental Duplication Database
 
Resource Report
Resource Website
1+ mentions
Non-Human Genome Segmental Duplication Database (RRID:SCR_000470) data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 16, 2013. It contains information about segmental duplications in the genomes of chimpanzee, mouse, and rat. The criteria used to identify regions of segmental duplication are: * Sequence identity of at least 90% * Sequence length of at least 5 kb * Not be entirely composed of repetitive elements. BACKGROUND: The high quality of the mouse genome draft sequence and its associated annotations are an invaluable biological resource. Identifying recent duplications in the mouse genome, especially in regions containing genes, may highlight important events in recent murine evolution. In addition, detecting recent sequence duplications can reveal potentially problematic regions of the genome assembly. We use BLAST-based computational heuristics to identify large (>/= 5 kb) and recent (>/= 90% sequence identity) segmental duplications in the mouse genome sequence. Here we present a database of recently duplicated regions of the mouse genome found in the mouse genome sequencing consortium (MGSC) February 2002 and February 2003 assemblies. RESULTS: We determined that 33.6 Mb of 2,695 Mb (1.2%) of sequence from the February 2003 mouse genome sequence assembly is involved in recent segmental duplications, which is less than that observed in the human genome (around 3.5-5%). From this dataset, 8.9 Mb (26%) of the duplication content consisted of "unmapped" chromosome sequence. Moreover, we suspect that an additional 18.5 Mb of sequence is involved in duplication artifacts arising from sequence misassignment errors in this genome assembly. By searching for genes that are located within these regions, we identified 675 genes that mapped to duplicated regions of the mouse genome. Sixteen of these genes appear to have been duplicated independently in the human genome. From our dataset we further characterized a 42 kb recent segmental duplication of Mater, a maternal-effect gene essential for embryogenesis in mice. CONCLUSION: Our results provide an initial analysis of the recently duplicated sequence and gene content of the mouse genome. Many of these duplicated loci, as well as regions identified to be involved in potential sequence misassignment errors, will require further mapping and sequencing to achieve accuracy. A Genome Browser database was set up to display the identified duplication content presented in this work. This data will also be relevant to the growing number of investigators who use the draft genome sequence for experimental design and analysis. The segmental duplication data and summary statistics are available for download and can also be visualized in a genome browser in the GBrowse section. Selected annotation tracks (except the segmental duplication track) have also been obtained from UCSC and loaded into the genome browser. Detailed information (e.g. overlapping genes, overlapping clones, detailed alignment) can be obtained by clicking on a duplication cluster in GBrowse. Both keyword search and BLAT search are available. Analyses based on previous genome assemblies can be found in the Previous Analyses section. Recent Developments The Non-Human Genome Segmental Duplication Database is continually updated including the archived copies of the analysis of all previous genome assemblies and will include all new species as they become available. Acknowledgments We thank The Centre for Applied Genomics at the Hospital for Sick Children (HSC) as well as collaborators worldwide. Supported by Genome Canada the Howard Hughes Medical Institute International Scholar Program (to S.W.S.) and the HSC Foundation. genes, genome, chicken, chimpanzee, chromosome, dna, dog, mouse, rat, segmental duplications THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-03194 SCR_000470 Non-Human Genome Segmental Duplication Database 2026-09-12 01:01:19 1
Bovine Genome Database
 
Resource Report
Resource Website
10+ mentions
Bovine Genome Database (RRID:SCR_000148) BGD data or information resource, database Database and integrated tools to improve annotation of the bovine genome and to integrate the genome sequence with other genomics data. genome browser, genome is listed by: OMICtools
has parent organization: University of Missouri; Missouri; USA
USDA National Institute of Food and Agriculture 2007-35616-17882;
USDA National Institute of Food and Agriculture 2010-65205-20407
PMID:21123190
PMID:21092105
Acknowledgement requested OMICS_04529 SCR_000148 The Bovine Genome Database, BovineGenome.org 2026-09-12 01:01:18 15

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