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https://winshipcancer.emory.edu/research/shared-resources/emory-cellular-immunotherapy-core.html

Clinical cell manufacturing facility that prepares cell and immunotherapy products under current Good Manufacturing Practices for development of investigational new drugs and diagnostics methods.Provides GMP compliant cell manufacturing and/or consultation for translational of Emory based or external research collaborations into early phase clinical trials.

Proper citation: Emory University Emory Cellular and Immunotherapy Core Facility (RRID:SCR_023533) Copy   

•   Source: SciCrunch Registry

http://fgc.arizona.edu

Offers to run high-throughput compound, RNAi, and deletion library based screens for purpose of network analysis, drug and/or target discovery. Offers assistance to develop assay, carryout screen and/or analyze data. Equipment is also available for general (low-throughput) use. Helps with developing custom pipeline. Biomek FX liquid handling workstation with integrated Liconic shaker incubator (temperature, humidity, and CO2 controlled) can be used to setup and grow most cell types in 96 well plates. This robot is equipped to add RNAi constructs, drugs or other stimuli to each plate. Biomek FX can also be used to perform high-throughput biochemical assays. Cell based assays can be carried out using either Operetta CLS high-content analysis system or CLARIOstar plus. Both instruments have powerful, but easy to use software for data analysis.

Proper citation: University of Arizona Functional Genomics Core Facility (RRID:SCR_023433) Copy   

•   Source: SciCrunch Registry

https://med.miami.edu/research/cores/biomarker-and-immunoassay-laboratory

Provides biomarker testing for human clinilcal research studies across multiple disciplines.Provides expertise with chemistry, special chemistry, radioimmunoassay, nephelometric and ELISA and multiplexing assay methods utilizing automated and manual procedures. Laboratory has Clinical Laboratory Improvement Act certification and follows guidelines established by CLIA for quality control and proficiency testing to ensure results. Core coordinates proper pre-analytical sample collection and processing procedures with project leaders; performs biochemical assays on samples submitted to the laboratory by investigators in manner that assures strict quality control both within and between assay runs; reports results to project staff in timely fashion; makes available expertise and technical assistance for establishing and validating new methodologies to support University of Miami investigators.

Proper citation: University of Miami Miller School of Medicine Biomarkers and Immunoassay Laboratory Core Facility (RRID:SCR_023705) Copy   

•   Source: SciCrunch Registry

https://research.pasteur.fr/en/team/human-disease-models-core-facility/

Core Facility produces mice harboring human immune system and provides expertise for possible applications of this model. HIS mice engrafted with human Hematopoietic stem cells are advantageous in vivo models for long term studies in field of human immune cells biology, immune oncology and infectious disease. They constitute small animal model in which to analyze potency and safety of small animal model modulating immune system.

Proper citation: Pasteur Institute Human Disease Models Core Facility (RRID:SCR_023881) Copy   

•   Source: SciCrunch Registry

https://imaging.au.dk

Core Facility offers equipment for wide range of light microscopy applications as well as access to advanced bioimaging software. Specialized staff offers personal training and assistance.

Proper citation: Aarhus University Bioimaging Core Facility (RRID:SCR_023876) Copy   

•   Source: SciCrunch Registry

https://www.beatson.gla.ac.uk/advanced-technologies/bair.html

Core to uncover and interrogate important molecular pathways in cancer. Offers training scientists in all stages of modern microscopical research from advice on experimental design and sample preparation, basic and advanced microscope operation and data acquisition through to quantitative image analysis and interpretation.

Proper citation: Beatson Institute for Cancer Research United Kingdom Beatson Advanced Imaging Resource Core Facility (RRID:SCR_023875) Copy   

•   Source: SciCrunch Registry

https://bic.nd.edu/

Offers instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for isolation and purification of macromolecules for subsequent detailed biophysical analysis.

Proper citation: University of Notre Dame ND Biophysics Instrumentation Core Facility (RRID:SCR_023867) Copy   

•   Source: SciCrunch Registry

https://www.cch.uleth.ca

Provides comprehensive solution characterization of macromolecules or macromolecular interactions and assemblies. This includes description of stoichiometry, size composition, cargo loading.Core is equipped with analytical ultracentrifuges featuring multi-wavelength UV-visible detection, as well as Rayleigh interference optics and fluorescence emission detection for fluorescent tags with 488 nm excitation.

Proper citation: University of Lethbridge Canadian Center for Hydrodynamics Core Facility (RRID:SCR_023791) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/nanoimaging/index.html

Provides service and expert advice to researches in their projects related to nanoimaging studies of molecular systems at single molecule and single cell levels utilizing Atomic Force Microscope, combination of Atomic Force Microscope with Fluorescence Optical Microscope, combination of Atomic Force Microscope with Raman Spectroscopy.

Proper citation: University of Nebraska Medical Center Nanoimaging Core Facility (RRID:SCR_018828) Copy   

•   Source: SciCrunch Registry

http://www.med.nyu.edu/ocs/cytometry-and-cell-sorting-core

Facility provides cytometry and cell sorting services. Services include immunophenotyping, cell cycle analysis, and intracellular fluorophore detection. Services can be tailored to research needs, certified cytometrists are available to help plan experiments. Offers online and hands-on training in use of cell analyzers and analysis software.

Proper citation: New York University School of Medicine Langone Cytometry and Cell Sorting Core Facility (RRID:SCR_018827) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/vger

Provides services, consultation, and collaborations to enable generation, storage and regeneration of genetically altered mice.Services include CRISPR-Cas9 Mouse Editing, Pronuclear Microinjection of DNAs,Sperm or Embryo Cryopreservation,In vitro Fertilization and Rederivation,Genome-Editing Design and Analysis Services.

Proper citation: Vanderbilt University Genome Editing Resource Core Facility (RRID:SCR_018826) Copy   

•   Source: SciCrunch Registry

https://research.uky.edu/abebc

Core primary focus is to identify mechanisms linking obesity to cardiovascular disease. Provides equipment and technical expertise for measurement of lean/fat mass and whole body metabolism in mice. Provides equipment for computerized quantitative measurement of oxygen consumption, food intake, water intake, and physical activity in mice.Echo MRI is utilized for non invasive quantitative assessment of lean and fat mass.

Proper citation: Kentucky University, Lexington, Energy Balance and Body Composition Core Facility (RRID:SCR_018825) Copy   

•   Source: SciCrunch Registry

https://www.biotech.iastate.edu/Hybridoma/

Core provides services for monoclonal or polyclonal antibodies production,animal immunization, cell fusion and hybridoma culture maintenance, cell culture and maintenance of other cell lines used in biotechnology and virology labs, large scale mammalian cell culture (bioreactor), blood sera collection, antibody purification and isotyping, cryopreservation and cryostorage of cell lines, and ELISA tests.

Proper citation: Iowa State University Hybridoma Core Facility (RRID:SCR_018829) Copy   

•   Source: SciCrunch Registry

https://isb3d.pharmacy.vcu.edu/resources/

Core provides services for Molecular Modeling, Biophysical Techniques, X-ray Crystallography, Protein Production,High Throughput Screening. Provided instruments to use after reservation include Clariostar Multimode Plate Reader, Echo 550 Acoustic Liquid Handler, X-Ray Diffractometer.

Proper citation: Virginia Commonwealth University School of Pharmacy Institute for Structural Biology, Drug Discovery and Development Core Facility (RRID:SCR_018832) Copy   

•   Source: SciCrunch Registry

https://www.unlv.edu/genomics

Provides development and support of genomics-based research, serving investigators in Nevada and beyond. Staff can be contracted for select services including ABI 3130 DNA sequencing, BD FACSCalibur flow cytometry, Affymetrix microarray processing, Agilent 2100 Bioanalyzer analysis and Qubit analysis. Facility also provides equipment and training for real-time PCR, Western blot/gel/microarray scanning, and analysis of DNA, RNA and protein samples.

Proper citation: Nevada University Genomics Core Facility (RRID:SCR_018272) Copy   

•   Source: SciCrunch Registry

http://www.kendricklabs.com

Contract Research Org. specializing in custom protein analysis. Services Provided include SDS PAGE analysis, Western Blotting, Mass Spectrometry, protein staining ( silver,coomassie) for academia, federal institutions and industry.

Proper citation: Kendrick Labs Core Facility (RRID:SCR_018271) Copy   

•   Source: SciCrunch Registry

http://cmi.hms.harvard.edu

Core provides scientific consultation, training and access to shared biophysical equipment for characterization and analysis of macromolecules and their complexes. Facility includes instruments measuring molecular interactions and assessing protein quality by Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), MicroScale Thermophoresis (MST), Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), Analytical Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS), and Dynamic Light Scattering (DLS).

Proper citation: Harvard Medical School Center for Macromolecular Interactions Core Facility (RRID:SCR_018270) Copy   

•   Source: SciCrunch Registry

https://flow.ucsf.edu/

Core assists investigators whose research requires molecular marker characterization of cells in suspension as well as isolation of cells based on those markers. Advanced cell sorting and cytometric analyses by Flow or Mass Cytometry are provided.

Proper citation: University of California San Francisco Parnassus Flow Cytometry Core Facility (RRID:SCR_018206) Copy   

•   Source: SciCrunch Registry

http://cqls.oregonstate.edu/

Formerly Center for Genome Research and Biocomputing Core Facility. Functions and facilities include services in genomics, functional genomics, genotyping and imaging.Biocomputing facilities with computing infrastructure, which includes managed cloud and shared resources, data analyses and training are customized to individual needs, including genome assembly and annotation, analysis of RNAseq, GBS, and metagenomics data, and GPU-enabled deep learning analyses.

Proper citation: Oregon State University Center for Quantitative Life Sciences Core Facility (RRID:SCR_018373) Copy   

•   Source: SciCrunch Registry

http://www.med.uvm.edu/mic

Core provides imaging equipment including JEOL 1400 transmission electron microscope with AMT 11 megapixel digital camera,JEOL JSM 6060 scanning electron microscope with attached Oxford INCA energy dispersive spectroscopy detector for element analysis,Nikon Air HD confocal scanning laser microscope, Nikon C2 confocal scanning laser microscope, Andor Spinning Disk confocal microscope, Zeiss LSM 7 Multiphoton confocal microscope, Nikon STORM super-resolution light microscope, Olympus BX50 research microscope for transmitted light, phase contrast, and epi-fluorescence microscopy, Asylum Research MFP-3D BIO atomic force microscope, Asylum Research Cypher Environmental atomic force microscope,Arcturus XT-Ti Laser Capture Microdissector system, Olympus IX70 inverted microscope with associated Applied BioPhysics Electri Cell-Substrate Impedance Sensing (ECIS Ztheta) system, Leica VERSA 8 whole slide imager, Dell workstations containing Molecular Devices MetaMorph image analysis software for complex quantitative image analysis, Indica Labs HALO software, Improvision Volocity, MBR StereoInvestigator.

Proper citation: Vermont University Larner College of Medicine Microscopy Imaging Center Core Facility (RRID:SCR_018821) Copy   

•   Source: SciCrunch Registry