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https://github.com/gaow/genetic-analysis-software/blob/master/pages/MAPMAKER%26SIBS.md
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 22, 2016. Data analysis software for complete multipoint analysis.
Proper citation: MAPMAKER/SIBS (RRID:SCR_008012) Copy
A cell repository containing cells and DNA for studies of aging and the degenerative processes associated with it. Scientists use the highly-characterized, viable, and contaminant-free cell cultures from this collection for research on such diseases as Alzheimer's disease, progeria, Parkinson's disease, Werner syndrome, and Cockayne syndrome. The collections of the Repository include DNA and cell cultures from individuals with premature aging disorders, as well as DNA from individuals of advanced age from the the Baltimore Longitudinal Study of Aging at the Gerontology Research Center and other Longevity Collections. The Repository also includes samples from an Adolescent Study of Obesity, Apparently Healthy Controls, Animal Models of Aging, and both human and animal differentiated cell types. The cells in this resource have been collected over the past three decades using strict diagnostic criteria and banked under the highest quality standards of cell culture. Scientists can use the highly-characterized, viable, and contaminant-free cell cultures from this collection for genetic and cell biology research.
Proper citation: Aging Cell Repository (RRID:SCR_007320) Copy
http://www.stat.washington.edu/thompson/Genepi/MORGAN/Morgan.shtml
Software programs for segregation and linkage analysis, using a variety of Markov chain Monte Carlo (MCMC) methods. Includes MCMC methods for multilocus gene identity by descent (including homozygosity mapping) and Monte Carlo Lod scores. Also, other programs for EM analysis of quantitative traits.
Proper citation: MORGAN (RRID:SCR_006906) Copy
http://www.pierroton.inra.fr/genetics/labo/Software/Famoz/index.html
Software application that uses likelihood calculation and simulation to perform parentage studies with codominant, dominant, cytoplasmic markers or combinations of the different types (entry from Genetic Analysis Software)
Proper citation: FAMOZ (RRID:SCR_007477) Copy
http://www.mds.qmw.ac.uk/statgen/dcurtis/software.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5th,2023. Software application that uses Monte Carlo method for assessing significance of a case-control association study with multi-allelic marker. (entry from Genetic Analysis Software).
Proper citation: CLUMP (RRID:SCR_007476) Copy
http://www.thomaskoenig.ch/Lester/ibaspm.htm
The aim of this work is to present a toolbox for structure segmentation of structural MRI images. All programs were developed in MATLAB based on a widely used fMRI, MRI software package, SPM99, SPM2, SPM5 (Wellcome Department of Cognitive Neurology, London, UK). Other previous works have developed a similar strategy for obtaining the segmentation of individual MRI image into different anatomical structures using a standardized Atlas. Have to be mentioned the one introduced by Montreal Neurological Institute (MNI) that merges the information coming from ANIMAL (algorithm that deforms one image (nonlinear registration) to match previously labelled) and INSECT (Cerebral Tissue Classification) programs for obtaining a suitable gross cortical structure segmentation (Collins et al, 1999). Here both, nonlinear registration and gray matter segmentation processes have been performed through SPM99, SPM2, SPM5 subroutines. Three principal elements for the labeling process are used: gray matter segmentation, normalization transform matrix (that maps voxels from individual space to standardized one) and MaxPro MNI Atlas. All three are combined to yield a good performance in segmenting gross cortical structures. The programs here can be used in general for any standardized Atlas and any MRI image modality. System Requirements: 1. The IBASPM graphical user interface (GUI) runs only under MATLAB 7.0 or higher. The non-graphical version runs under MATLAB 6.5 or higher. 2. Statistical Parametrical Mapping Software SPM2, SPM5 Main Functions: * Atlasing: Main function ( This file contains spm_select script from SPM5 toolbox and uigetdir script from MATLAB 7.0 ). * Auto_Labeling : Computes individual atlas. * Create_SPAMs : Constructs Statistical Probability Anatomy Maps (SPAMs). * Create_MaxProb : Creates Maximum Probability Atlas (MaxPro) using the SPAMs previously computed. * All_Brain_Vol : Computes whole brain volume masking the brain using the segmentation files (if the segmentation files does not exist it segments). * Struct_Vol : Computes the volume for different structures based on individual Atlas previously obtained by the atlasing process. * Vols_Stats : Computes mean and standard deviation for each structure in a group of individual atlases.
Proper citation: IBASPM: Individual Brain Atlases using Statistical Parametric Mapping Software (RRID:SCR_007110) Copy
http://liweilab.genetics.ac.cn/tm/
Web-based tool used to mine human protein-protein interactions (PPIs) from PubMed abstracts based on their co-occurrences and interaction words, followed by evidencs in human PPI databases and shared terms in GO database.
Proper citation: Human Protein-Protein Interaction Mining Tool (RRID:SCR_008040) Copy
http://www.birncommunity.org/tools-catalog/gradient-non-linearity-distortion-correction/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 16,2023. Software tool to correct gradient non-linearity distortions in MR structural images. This correction improves test-retest reproducibility crucial for multi-site studies.
Proper citation: Gradient Non-linearity Distortion Correction (RRID:SCR_007350) Copy
http://www.bcgsc.ca/platform/bioinfo/software/alea
A computational software toolbox for allele-specific (AS) epigenomics analysis. It incorporates allelic variation data within existing resources, allowing for the identification of significant associations between epigenetic modifications and specific allelic variants in human and mouse cells. It provides a customizable pipeline of command line tools for AS analysis of next-generation sequencing data (ChIP-seq, RNA-seq, etc.) that takes the raw sequencing data and produces separate allelic tracks ready to be viewed on genome browsers. ALEA takes advantage of the available genomic resources for human (The 1000 Genomes Project Consortium) and mouse (The Mouse Genome Project) to reconstruct diploid in-silico genomes for human or hybrid mice under study. Then, for each accompanying ChIP-seq or RNA-seq dataset, it generates two Wiggle track format (WIG) files from short reads aligned differentially to each haplotype.
Proper citation: ALEA (RRID:SCR_006417) Copy
http://darwin.uvigo.es/software/treescan.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 11, 2023. Software application that is intended to provide p-values for the hypothesis of association between evolutionary clades and continuous traits, using haplotype trees. (entry from Genetic Analysis Software)
Proper citation: TREESCAN (RRID:SCR_007108) Copy
http://pngu.mgh.harvard.edu/purcell/whap/
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 24, 2015. This package is no longer supported. The majority of the functionality for conditional haplotype tests in population-based samples has been implemented in PLINK, with a better interface and more robust, faster computation: please use that from now on. Software tool to perform haplotype-based association analysis, for quantitative and qualitative traits, in population and family samples, using single nucleotide polymorphism or multiallelic marker data. What whap can do: * Analyze quantitative and qualitative traits * Handle unrelated individuals and/or parent-offspring trio data * Perform a regression-based haplotype association test for SNP data * Perform a secondary test based on pairwise haplotype similarity * Phase genotype data using a standard E-M approach, and handle ambiguity in E-M inferred haplotypes * Include covariates and moderator variables * Flexibly constrain effects across haplotypes to tested nested models * Perform a robust within-family test when parental genotypes are present * Analyze multiallelic markers (new) * Use dominant or recessive (new) genetic models (new)
Proper citation: Whap (RRID:SCR_007103) Copy
Find all news and updates about INCF and neuroinformatics in the International Neuroinformatics Coordinating Facility (INCF) Newsroom.
Proper citation: INCF Newsroom (RRID:SCR_006493) Copy
http://www.vivo.colostate.edu/molkit/index.html
The Molecular Toolkit is a group of programs for analysis and manipulation of nucleic acid and protein sequence data. The programs are written in Java (1.0) and require that your browser support this language. Also, it''s best if your monitor supports a screen resolution of at least 800x600. Nucleic Acid Analysis and Manipulation Programs: *Dot Plots - Examine the similarity of two DNA (or RNA) sequences by production of a similarity matrix displayed as a dot plot. *Manipulate and Display Sequences - Perform simple manipulations on a DNA sequence (inverse, complement, inverse-complement, double-stranded etc). *Restriction Maps - Generate graphical and text-based maps for restriction endonuclease cleavage of DNA. *Translate - Translate a DNA or RNA sequence and obtain graphical and text depictions of the resulting protein sequences. Protein Analysis Programs *Reverse Translate - Reverse translate a protein sequence into DNA. *Protein Composition - Obtain the amino acid composition of a protein. *Hydrophobicity Plots - Plot hydrophobic and hydrophilic domains of a protein.
Proper citation: Molecular Toolkit (RRID:SCR_007068) Copy
http://mga.bionet.nsc.ru/soft/mgamapf2/
Software application that map QTLs in F-2 intercross in model organisms (entry from Genetic Analysis Software)
Proper citation: MGA-MAPF2 (RRID:SCR_008108) Copy
http://wpicr.wpic.pitt.edu/WPICCompGen/
Software application (entry from Genetic Analysis Software)
Proper citation: R/SPECTRAL-GEM (RRID:SCR_007414) Copy
Software repository for R packages related to analysis and comprehension of high throughput genomic data. Uses separate set of commands for installation of packages. Software project based on R programming language that provides tools for analysis and comprehension of high throughput genomic data.
Proper citation: Bioconductor (RRID:SCR_006442) Copy
http://openccdb-dev-web.crbs.ucsd.edu/software/index.shtm
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 4th,2023. Software application that is a web-based tool for viewing and annotating images. The application is based on the open source Google Web Toolkit (GWT) version 1.7, which generates Javascript code that runs on the user''s web browser. No special installation or software other than a Javascript-enabled web browser is required for use. Images to be viewed or annotated are preprocessed into multi-resolution tiles by either the commercial Zoomify preprocessor application or a locally written `zoomify_create'' tool, which produces lossless Portable Network Graphics (PNG) tiles. The WebImageBrowser application reads and manages tiled images in a manner similar to Google Maps or similar applications, allowing viewing of images of arbitrarily large size. The source code is available at https://github.com/OpenCCDB/WebImageBrowser . It requires a build. If you want the annotation function to be enabled, then you will need to install the CCDB schema in the Postgres database.
Proper citation: WebImageBrowser (RRID:SCR_007015) Copy
http://www.uni-bonn.de/~umt70e/soft.htm
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5th,2023. Software application for calculation of the restricted likelihood-ratio affected sib-pair test for linkage allowing for imprinting (entry from Genetic Analysis Software)
Proper citation: ILR (RRID:SCR_007895) Copy
http://ki.se/ki/jsp/polopoly.jsp?d=29332&a=103697&l=en
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 3rd,2023. Recently it has been discovered that specific Single Nucleotide Polymorphisms (SNPs) may elevate the risk of developing prostate cancer. This study aims at investigating whether it is possible to use these SNPs in a clinical setting in order to sharpen the diagnostic tools when investigating if a man has prostate cancer. By collecting blood from men who have undergone a needle biopsy of the prostate and do a SNP analysis of their genes and compare this with the result of the biopsy and PSA result we hope to be able to develop a test that is more specific than the routine that is being used today. Sample types: * EDTA whole blood * DNA Number of sample donors: 5321 (June 2010)
Proper citation: SPSAC - Stockholm PSA Cohort (RRID:SCR_006042) Copy
http://csg.sph.umich.edu/boehnke/sibmed.php
Software application that identifies likely genotyping errors and mutations for a sib pair in the context of multipoint mapping. (entry from Genetic Analysis Software)
Proper citation: SIBMED (RRID:SCR_007495) Copy
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