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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/release/bioc/html/ArrayExpress.html
Software to access the ArrayExpress Repository at EBI and build Bioconductor data structures: ExpressionSet, AffyBatch, NChannelSet
Proper citation: ArrayExpress (R) (RRID:SCR_000120) Copy
http://www.bioconductor.org/packages/release/bioc/html/AffyRNADegradation.html
Software package that helps with the assessment and correction of RNA degradation effects in Affymetrix 3' expression arrays. The parameter d gives a robust and accurate measure of RNA integrity. The correction removes the probe positional bias, and thus improves comparability of samples that are affected by RNA degradation.
Proper citation: AffyRNADegradation (RRID:SCR_000118) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/VariantAnnotation.html
Software package to annotate variants, compute amino acid coding changes, and predict coding outcomes.
Proper citation: VariantAnnotation (RRID:SCR_000074) Copy
http://www.bioconductor.org/packages/release/bioc/html/timecourse.html
Software functions for data analysis and graphical displays for developmental microarray time course data.
Proper citation: timecourse (RRID:SCR_000077) Copy
http://bioconductor.org/packages/release/bioc/html/CorMut.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 16,2023. Software package for computing correlated mutations based on selection pressure. Three methods are provided for detecting correlated mutations, including conditional selection pressure, mutual information and Jaccard index. The computation consists of two steps: First, the positive selection sites are detected; second, the mutation correlations are computed among the positive selection sites. Note that the first step is optional. Meanwhile, CorMut facilitates the comparison of the correlated mutations between two conditions by the means of correlated mutation network.
Proper citation: CorMut (RRID:SCR_000053) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowBin.html
A software package to combine flow cytometry data that has been multiplexed into multiple tubes with common markers between them. It establishes common bins across tubes in terms of the common markers, then determines expression within each tube for each bin in terms of the tube-specific markers.
Proper citation: flowBin (RRID:SCR_000051) Copy
http://www.bioconductor.org/packages/release/bioc/html/metaSeq.html
Software package for meta-analysis of RNA-Seq count data in multiple studies. The probabilities by one-sided NOISeq are combined by Fisher's method or Stouffer's method.
Proper citation: metaSeq (RRID:SCR_000056) Copy
http://www.bioconductor.org/packages/release/bioc/html/rqubic.html
This software package implements the QUBIC algorithm for the qualitative biclustering with gene expression data.
Proper citation: rqubic (RRID:SCR_012869) Copy
http://bioconductor.org/packages/release/bioc/html/DiffBind.html
Compute differentially bound sites from multiple ChIP-seq experiments using affinity (quantitative) data. Also enables occupancy (overlap) analysis and plotting functions.
Proper citation: DiffBind (RRID:SCR_012918) Copy
http://www.bioconductor.org/packages/release/bioc/html/iBBiG.html
A bi-clustering algorithm which is optimizes for binary data analysis.
Proper citation: iBBiG (RRID:SCR_012882) Copy
http://www.bioconductor.org/packages/release/bioc/html/eisa.html
A biclustering method; it finds correlated blocks (transcription modules) in gene expression (or other tabular) data.
Proper citation: eisa (RRID:SCR_012883) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/TurboNorm.html
Software providing a fast scatterplot smoother suitable for microarray normalization based on B-splines with second-order difference penalty. Functions for microarray normalization of single-colour data i.e. Affymetrix/Illumina and two-colour data supplied as marray MarrayRaw-objects or limma RGList-objects are available.
Proper citation: TurboNorm (RRID:SCR_012963) Copy
http://www.bioconductor.org/packages/release/bioc/html/methylumi.html
Software package that provides classes for holding and manipulating Illumina methylation data.
Proper citation: Methylumi (RRID:SCR_012831) Copy
http://www.bioconductor.org/packages/release/bioc/html/iChip.html
Software package that uses hidden Ising models to identify enriched genomic regions in ChIP-chip data.
Proper citation: iChip (RRID:SCR_012958) Copy
http://www.bioconductor.org/packages/release/bioc/html/NarrowPeaks.html
Software package for post-processing of peaks and differential binding in ChIP-seq based on standard wiggle visualization files. The double aim of the package is to apply a functional version of principal component analysis (FPCA) to: (1) Process data in wiggle track format (WIG) commonly produced by ChIP-seq peak finders by applying FPCA over a set of selected candidate enriched regions. This is done in order to shorten the genomic locations accounting for a given proportion of variation among the enrichment-score profiles. The function ''narrowpeaks'' allows the user to discriminate between binding regions in close proximity to each other and to narrow down the length of the putative transcription factor binding sites while preserving the information present in the variability of the dataset and capturing major sources of variation. (2) Analyze differential variation when multiple ChIP-seq samples need to compared. The function ''narrowpeaksDiff'' quantifies differences between the tag-enrichment, and uses non-parametric tests on the FPC scores for testing differences between conditions.
Proper citation: NarrowPeaks (RRID:SCR_012924) Copy
http://www.bioconductor.org/packages/2.13/bioc/html/ChAMP.html
Software package that includes quality control metrics, a selection of normalization methods and novel methods to identify differentially methylated regions and to highlight copy number aberrations.
Proper citation: ChAMP (RRID:SCR_012891) Copy
http://bioconductor.org/packages/release/bioc/html/CSAR.html
Statistical tools for the analysis of ChIP-seq data.
Proper citation: CSAR (RRID:SCR_012930) Copy
http://www.bioconductor.org/packages/2.13/bioc/html/CSSP.html
Software for power computation for ChIP-Seq data based on Bayesian estimation for local poisson counting process.
Proper citation: CSSP (RRID:SCR_012932) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/cghMCR.html
Software package that provides functions to identify genomic regions of interest based on segmented copy number data from multiple samples.
Proper citation: cghMCR (RRID:SCR_012898) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/RankProd.html
Software using a non-parametric method for identifying differentially expressed (up- or down- regulated) genes based on the estimated percentage of false predictions (pfp).
Proper citation: RankProd (RRID:SCR_013046) Copy
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