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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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IFPMA Clinical Trials Portal Resource Report Resource Website |
IFPMA Clinical Trials Portal (RRID:SCR_000791) | data or information resource, database | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. IFPMA Clinical Trials Portal is brought to you by IFPMA on behalf of its Member Companies and Associations. IFPMA Clinical Trials Portal ensures: a free and easy-to-use interface for patients and health professionals alike to ongoing clinical trials, clinical trial results and complementary information on related issues; non-promotional and reliable information; industry's commitment to the transparency of clinical trials. * Search by Medical Condition and Drug Name * Language Interfaces (En, Es, Fr, De, Jp) * Glossary and Easy Explanation of Medical Expressions * Geographical Search | clinical, clinical trial, pediatric, disease, cancer, hiv, aids, diabetes, heart disease | has parent organization: IFPMA - International Federation of Pharmaceutical Manufacturers and Associations | IFPMA - International Federation of Pharmaceutical Manufacturers and Associations | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-31391 | SCR_000791 | International Federation of Pharmaceutical Manufacturers and Associations Clinical Trials Portal | 2026-09-12 01:01:21 | 0 | |||||||
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BIOAIR - BIOmarkers in severe Chronic AIRway Disease Resource Report Resource Website 1+ mentions |
BIOAIR - BIOmarkers in severe Chronic AIRway Disease (RRID:SCR_006007) | BIOAIR | biomaterial supply resource, material resource | THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. Longitudinal Assessment of Clinical Course and BIOmarkers in severe Chronic AIRway Disease (BIOAIR) is a study within the European Network For Understanding Mechanisms Of Severe Asthma (ENFUMOSA). BIOAIR study involves studies of severe asthma. The 10% of all asthmatics who have the most difficult disease has a 5-year survival in level with severe cancer diseases, as well as account for half of the costs to society of asthma. Mechanisms for the development of severe asthma, however, is unknown. BIOAIR the project characterizes clinical Phenotype and biomarkers in a study involving 12 centers in nine European countries. In a longitudinal study comparing severe asthmatics with mild asthmatics and patients with COPD (Chronic obstructive pulmonary disease). Clinical data and medicine consumption are collected daily in over a year with the help of modern IT technology. Blood tests, urine samples, upphostningsprover and bronkialbiopsier are collected repeatedly and tested for a wide range of possible pathogenetic factors, including genotype. | longitudinal, clinical, biomarker, chronic airway disease, phenotype, medication, clinical data, genotype, pathogen, lung disease |
is listed by: One Mind Biospecimen Bank Listing has parent organization: Karolisnka Biobank |
Asthma, Chronic obstructive pulmonary disease | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_151388 | SCR_006007 | BIOmarkers in severe Chronic AIRway Disease, BIOmarkers in severe Chronic AIRway Disease (BIOAIR), KI Biobank - BIOAIR | 2026-09-12 01:02:35 | 1 | ||||||
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PhenoTips Resource Report Resource Website 10+ mentions |
PhenoTips (RRID:SCR_006340) | PhenoTips | software application, software resource | A software tool providing a Web interface and a database back-end for collecting clinical symptoms and physical findings observed in patients with genetic disorders. The main goals of this software are * To allow for collecting patient data in standard formats, enabling effortless data exchange and automated search in annotated gene and disease databases, and * To provide advanced functionalities and a friendly user interface that help reduce the clinician''''s workload, permitting seamless use of this application within the clinician''''s routine. PhenoTips uses the Human Phenotype Ontology (HPO) to express clinical phenotypes, and provides a friendly interface with error-tolerant, predictive search of phenotypic descriptions. PhenoTips closely mirrors clinician workflows: observations can be recorded directly during the patient encounter, and the interface is compatible with any device that runs a modern Web browser. The clinician can record demographic information, family history, medical history, various standard measurements, phenotypic abnormalities detected in the patient, pertinent indications that were not observed and that can be helpful for differential diagnosis, relevant images depicting manifestations of the patient''''s disorders, and additional notes for each of these categories. The software automatically plots growth curves, selects phenotypes reflecting abnormal measurements, instantly finds OMIM disorders matching the phenotypic description and suggests other symptoms to investigate in order to reach a more accurate diagnosis. | clinical symptom, physical finding, clinical, phenotype, demographic information, family history, medical history, standard measurement, indication, image, note, growth curve |
is related to: Human Phenotype Ontology is related to: OMIM has parent organization: University of Toronto; Ontario; Canada |
Genetic disorder | Free | nlx_152049 | SCR_006340 | PhenoTips: phenotyping made easy | 2026-09-12 01:02:36 | 24 | ||||||
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National Alzheimer's Coordinating Center Resource Report Resource Website 50+ mentions |
National Alzheimer's Coordinating Center (RRID:SCR_007327) | NACC | biomaterial supply resource, material resource | A clinical research, neuropathological research and collaborative research database that uses data collected from 29 NIA-funded Alzheimer's Disease Centers (ADCs). The database consists of several datasets, and searches may be done on the entire database or on individual datasets. Any researcher, whether affiliated with an ADC or not, may request a data file for analysis or aggregate data tables. Requested aggregate data tables are produced and returned as soon as the queue allows (usually within 1-3 days depending on the complexity). | alzheimer's disease, brain, clinical, database, disease, human, neuropathological, neuropathology, specimen, tissue, FASEB list |
is listed by: One Mind Biospecimen Bank Listing is related to: Alzheimers Disease Genetics Consortium is related to: Alzheimers Disease Genetics Consortium is related to: National Cell Repository for Alzheimer's Disease has parent organization: University of Washington; Seattle; USA |
Alzheimer's disease, Dementing disorder, Dementia | NIH Blueprint for Neuroscience Research ; NIA U01 AG016976 |
Data are freely available to all researchers | nif-0000-00203 | SCR_007327 | National Alzheimer's Coordinating Center | 2026-09-12 01:02:37 | 54 | |||||
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GERON Resource Report Resource Website 1+ mentions |
GERON (RRID:SCR_008531) | GERON | software resource, software toolkit | A suite of web-based open source software programs for clinical and genetic study. The aims of this software development in the Laboratory of Neurogenetics, NIA, NIH are * Build retrievable clinical data repository * Set up genetic data bank * Eliminate redundant data entries * Alleviate experimental error due to sample mix-up and genotyping error. * Facilitate clinical and genetic data integration. * Automate data analysis pipelines * Facilitate data mining for genetic as well as environmental factors associated with a disease * Provide an uniformed data acquisition framework, regardless the type of a given disease * Accommodate the heterogeneity of different studies * Manage data flow, storage and access * Ensure patient privacy and data confidentiality/security. The GERON suite consists of several self contained and yet extensible modules. Currently implemented modules are GERON Clinical, Genotyping, and Tracking. More modules are planned to be added into the suite, in order to keep up with the dynamics of the research field. Each module can be used separately or together with others into a seamless pipeline. With each module special attention has been given in order to remain free and open to the academic/government user., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | clinical, genotyping, tracking, genetic, module, pipeline | has parent organization: Intramural Research Program | Aging | NIA | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-30610 | SCR_008531 | 2026-09-12 01:02:38 | 5 | ||||||
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Chronic Renal Insufficiency Cohort Study Resource Report Resource Website 1+ mentions |
Chronic Renal Insufficiency Cohort Study (RRID:SCR_009016) | CRIC Study, CRIC | biomaterial supply resource, material resource | A prospective observational national cohort study poised to make fundamental insights into the epidemiology, management, and outcomes of chronic kidney disease (CKD) in adults with intended long-term follow up. The major goals of the CRIC Study are to answer two important questions: * Why does kidney disease get worse in some people, but not in others? * Why do persons with kidney disease commonly experience heart disease and stroke? The CRIC Scientific and Data Coordinating Center at Penn receives data and provides ongoing support for a number of Ancillary Studies approved by the CRIC Cohort utilizing both data collected about CRIC study participants as well as their biological samples. The CRIC Study has enrolled over 3900 men and women with CKD from 13 recruitment sites throughout the country. Following this group of individuals over the past 10 years has contributed to the knowledge of kidney disease, its treatment, and preventing its complications. The NIDDKwill be extending the study for an additional 5 years, through 2018. An extensive set of study data is collected from CRIC Study participants. With varying frequency, data are collected in the domains of medical history, physical measures, psychometrics and behaviors, biomarkers, genomics/metabolomics, as well as renal, cardiovascular and other outcomes. Measurements include creatinine clearance and iothalamate measured glomerular filtration rate. Cardiovascular measures include blood pressure, ECG, ABI, ECHO, and EBCT. Clinical CV outcomes include MI, ischemic heart disease-related death, acute coronary syndromes, congestive heart failure, cerebrovascular disease, peripheral vascular disease, and composite outcomes. The CRIC Study has delivered in excess of 150,000 bio-samples and a dataset characterizing all 3939 CRIC participants at the time of study entry to the NIDDKnational repository. The CRIC Study will also be delivering a dataset to NCBI''''s Database for Genotypes and Phenotypes. | clinical, epidemiology, management, outcome, adult human, medical history, physical measure, psychometrics, behavior, renal, biomarker, genomics, gwas, kidney, data sharing, bibliography, observational cohort study, male, female, cardiovascular, heart, kidney, risk factor, metabolomics |
is listed by: One Mind Biospecimen Bank Listing is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources is listed by: Diabetes Research Centers is related to: NCBI database of Genotypes and Phenotypes (dbGap) is related to: NIDDK Central Repository is related to: AASK Clinical Trial and Cohort Study has parent organization: University of Pennsylvania Perelman School of Medicine; Pennsylvania; USA |
Chronic kidney disease, Cardiovascular disease | NIDDK | Proposals to carry out ancillary studies are welcome | nlx_152758 | SCR_009016 | Chronic Renal Insufficiency Cohort (CRIC) Study | 2026-09-12 01:02:38 | 2 | |||||
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TCMGeneDIT Resource Report Resource Website 10+ mentions |
TCMGeneDIT (RRID:SCR_013396) | data or information resource, database | TCMGeneDIT is a database system providing association information about traditional Chinese medicines (TCMs), genes, diseases, TCM effects and TCM ingredients automatically mined from vast amount of biomedical literature. Integrated protein-protein interaction and biological pathways information collected from public databases are also available. In addition, the transitive relationships among genes, TCMs and diseases could be inferred through the shared intermediates. Furthermore, TCMGeneDIT is useful in deducing possible synergistic or antagonistic contributions of the prescription components to the overall therapeutic effects. TCMGeneDIT is a unique database of various association information about TCMs. The database integrating TCMs with life sciences and biomedical studies would facilitate the modern clinical research and the understanding of therapeutic mechanisms of TCMs and gene regulations. | drug, gene, antagonistic, biomedical, clinical, disease, ingredient, interaction, life science, literature, medicine, pathway, prescription, protein, regulation, research, synergistic, therapeutic | has parent organization: National Taiwan University; Taipei; Taiwan | National Science Council Taiwan ; NTU Frontier and Innovative Research Projects NTUPFIR-96R0107 |
PMID:18854039 | nif-0000-32868 | SCR_013396 | 2026-09-12 01:02:11 | 14 | ||||||||
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ClinGen Resource Report Resource Website 1000+ mentions |
ClinGen (RRID:SCR_014968) | CGR | data or information resource, database | Genomics knowledgebase for clinical relevance of genes and variants for use in research. ClinGen's primary function is to store and share information for the benefit of the scientific community. Laboratory scientists, clinicians, and patients can share and access data. | database, knowledgebase, genomics, healthcare, clinical, FASEB list | is related to: CivicDb | Eunice Kennedy Schriver NICHD ; NHGRI U41 HG006834-01A1; NHGRI U01 HG007437-01; NHGRI U01 HG007436-01; NCI HHSN261200800001E; NCI contract HHSN261200800001E |
PMID:26014595 | Free, Available to the scientific community | SCR_014968 | Clinical Genome Resource (ClinGen), Clinical Genome Resource | 2026-09-12 01:02:15 | 1153 | ||||||
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Clinical Trial Management Application Resource Report Resource Website |
Clinical Trial Management Application (RRID:SCR_013531) | CTMA | software application, software resource | THIS RESOURCE IS NO LONGER IN SERVICE, documented on October 11, 2012. The Clinical Trials Management Tools are Java-based suite (accessed via a secure intranet) for managing various aspects of a clinical trial, research protocols, outcomes initiatives, statistical research analysis, as well as CTEP/CDUS reporting. Developed in collaboration with the Clinical Research Services (CRS) Office at the UPCI, this research-based application provides an integrated tool for managing administrative (e.g. IRB submissions and approvals) and clinical (e.g. tumor measurements, registrations/ screenings) functions for the collection and analysis of data generated from a clinical trial. More information can be found here, http://www.upci.upmc.edu/spore/skin/coreD.cfm | clinical trial, clinical, research protocol, outcomes initiative, statistical research analysis, ctep reporting, cdus reporting, clinical study, bioinformatics, computer platform, windows |
is listed by: Biositemaps has parent organization: University of Pittsburgh; Pennsylvania; USA |
THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-33266 | SCR_013531 | Clinical Trial Management Application (CTMA) | 2026-09-12 01:02:49 | 0 | |||||||
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NINDS Disorder Index Resource Report Resource Website |
NINDS Disorder Index (RRID:SCR_000433) | NINDS Disorder Index, NINDS Disorder List | data or information resource, data set | Reference disease data set of neurological diseases along with their definitions, etiology, treatment, prognosis, ongoing research, clinical trials information and publications. The Disorder Index includes synonyms and research topics. Navigation is by letter of the alphabet., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | genetic disorder, disease, disease progression, disorder, neurological disease, bibliography, clinical |
is used by: NIF Data Federation is related to: Integrated Disease has parent organization: National Institute of Neurological Disorders and Stroke |
THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-23200 | SCR_000433 | NINDS Disease List, Disorder Index: National Institute of Neurological Disorders and Stroke (NINDS), Disorders index from the National Institute of Neurological Disorders and Stroke (NINDS), NINDS Disorders A - Z, National Institute of Neurological Disorders and Stroke Disorder Index | 2026-09-12 01:03:09 | 0 | |||||||
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Center for In Vivo Microscopy Resource Report Resource Website 10+ mentions |
Center for In Vivo Microscopy (RRID:SCR_001426) | CIVM | biomedical technology research center, training resource | Biomedical technology research center dedicated to the development of novel imaging methods for the basic scientist and the application of the methods to important biomedical questions. The CIVM has played a major role in the development of magnetic resonance microscopy with specialized MR imaging systems capable of imaging at more than 500,000x higher resolution than is common in the clinical domain. The CIVM was the first to demonstrate MR images using hyperpolarized 3He which has been moved from mouse to man with recent clinical trials performed at Duke in collaboration with GE. More recently the CIVM has developed the molecular imaging workbench---a system dedicated to multimodality cardiopulmonary imaging in the rodent. Their collaborators are employing these unique imaging systems in an extraordinary range of mouse and rat models of neurologic disease, cardiopulmonary disease and cancer to illuminate the underlying biology and explore new therapies. | imaging, magnetic resonance microscopy, magnetic resonance imaging, clinical, mri, ct, x-ray, ultrasound, confocal, optical, spect | has parent organization: Duke University; North Carolina; USA | Cardiopulmonary disease, Cancer, Neurological disease | NIBIB 4P41EB015897-27 | Free, Freely Available | nlx_152650 | SCR_001426 | Duke Center for In Vivo Microscopy | 2026-09-12 01:03:11 | 10 | |||||
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National Center for Image-Guided Therapy Resource Report Resource Website 1+ mentions |
National Center for Image-Guided Therapy (RRID:SCR_001419) | NCIGT | biomedical technology research center, training resource | Biomedical Technology Resource Center that serves as a national resource for all aspects of research into medical procedures that are enhanced by imaging. Its common goal is to provide more effective patient care. The center is focused on the multidisciplinary development of innovative image-guided intervention technologies to enable effective, less invasive clinical treatments that are not only more economical, but also produce better results for patients. The NCIGT is helping to implement this vision by serving as a proving ground for some of the next generation of medical therapies. | clinical, patient care, imaging, medical procedure | has parent organization: Harvard Medical School; Massachusetts; USA | NIBIB P41EB015898 | Free, Freely Available | nlx_152641 | SCR_001419 | National Center for Image Guided Therapy | 2026-09-12 01:03:11 | 2 | ||||||
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fMRI Research Center at Columbia Resource Report Resource Website 10+ mentions |
fMRI Research Center at Columbia (RRID:SCR_002658) | PICS | access service resource, core facility, service resource | THIS RESOURCE IS NO LONGER IN SERVICE, documented on 7/28/13. Core facility of Columbia Neuroscience with the goal of establishing a collaborative and multi-investigator neuroimaging environment that is focused on the investigation of the neurocircuitry of the brain that underlies cognition, perception and action, and also the development of clinical applications that enhance the goals of personalized medicine. Within this environment the specific current research interests of the Hirsch group include several related directions of investigation. The first is conscious and subconscious neural processes that mediate emotion and cognition in healthy individuals and in patients with psychiatric disorders. This direction also includes neurocircuitry that is characteristic of disorders of consciousness such as minimally conscious or vegetative states, self and visual awareness, and attention. Neurocircuitry of other complex cognitive processes such as decisions, inductive and deductive reasoning, language, truthfulness and top-down influences of expectation, reward, and regulation on early visual and mid-level perceptual and emotional systems. On-going projects targeted for clinical applications include benefits for neurosurgery such as the development of task batteries to map the cortical locations of essential functions such as language, motor, sensation, memory, emotion and sensory functions including visions, audition and the chemical senses. Computational innovations for labeling correspondence between brain structure and specific functional regions are under development to achieve the highest interpretive precision. Current projects include integration of EEG and fMRI techniques to localize seizuregenic cortex in relation to eloquent and functioning cortex for neurosurgical planning; integration of TMS and fMRI to discriminate essential and associative language-sensitive cortical areas; and integration of VEP, EEG and fMRI to inform assessments of visual disease secondary to stroke or neural degeneration. Projects intended to refine and enhance diagnosis of psychiatric disorders such as anxiety, depression, and eating disorders include development of specialized paradigms to target dysfunctional neurocircuitry such as emotional systems (amygdala and basal ganglia) and control and regulatory systems (cingulate and pre-frontal cortex). Comparison of before-treatment images with after-treatment images to inform models of both treatment and disease and investigation of the hypothesis that individual genetic and functional differences have predictive value for treatment options and outcome are currently underway. The lab has pioneered techniques for functional mapping of single patients, and operates an active clinical service for mapping individuals for neurosurgical planning, assessments of the neurocircuitry that underlie acquired or inherited disabilities and the mechanisms of neuroplasticity that restore lost functions are actively investigated using both groups and single subject studies. : | fmri, imaging, neuroscience, cognitive sciences, cognition, perception, action, clinical, personalized medicine, neuroimaging, neurocircuitry, brain, vep, eeg | has parent organization: Columbia University; New York; USA | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-00405 | SCR_002658 | Program for Imaging and Cognitive Sciences, Program for Imaging & Cognitive Sciences | 2026-09-12 01:03:13 | 41 | |||||||
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Family Investigation of Nephropathy of Diabetes Resource Report Resource Website |
Family Investigation of Nephropathy of Diabetes (RRID:SCR_001525) | FIND, F.I.N.D. | clinical trial, resource | Multicenter observational study designed to identify genetic determinants of diabetic nephropathy. It is conducted in eleven U.S. clinical centers and a coordinating center, and with four ethnic groups (European Americans, African Americans, Mexican Americans, and American Indians). Two strategies are used to localize susceptibility genes: a family-based linkage study and a case-control study using mapping by admixture linkage disequilibrium (MALD). In the family-based study, probands with diabetic nephropathy are recruited with their parents and selected siblings. Linkage analyses will be conducted to identify chromosomal regions containing genes that influence the development of diabetic nephropathy or related quantitative traits such as serum creatinine concentration, urinary albumin excretion, and plasma glucose concentrations. Regions showing evidence of linkage will be examined further with both genetic linkage and association studies to identify genes that influence diabetic nephropathy or related traits. Two types of MALD studies are being done. One is a case-control study of unrelated individuals of Mexican American heritage in which both cases and controls have diabetes, but only the case has nephropathy. The other is a case-control study of African American patients with nephropathy (cases) and their spouses (controls) unaffected by diabetes and nephropathy; offspring are genotyped when available to provide haplotype data. The specific goals of this program: * Delineate genomic regions associated with the development and progression of renal disease(s) * Evaluate whether there is a genetic link between diabetic nephropathy and diabetic retinopathy * Improve outcomes * Provide protection for people at risk and slow the progression of renal disease * Help establish a resource for genetic studies of kidney disease and diabetic complications by creating a repository of genetic samples and a database * Encourage studies of the genetics of progressive renal disease | genetic susceptibility, genetic pathway, renal, kidney, outcome, gene, genetics, european-american, african-american, mexican-american, american-indian, linkage association study, admixture linkage disequilibrium, mapping by admixture linkage disequilibrium, serum creatinine, urinary protein excretion, plasma glucose level, blood pressure, blood lipid level, trait, linkage, adult human, male, female, clinical |
is listed by: ClinicalTrials.gov is listed by: NIDDK Information Network (dkNET) has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases |
NIDDK 5R01DK053591 | PMID:15642484 | Free, Freely available | nlx_152825 | https://www.niddkrepository.org/studies/find/ | SCR_001525 | Family Investigation of Nephropathy and Diabetes (F.I.N.D.), Family Investigation of Nephropathy & Diabetes | 2026-09-12 01:03:12 | 0 | ||||
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UNC Joint Vector Laboratories Resource Report Resource Website 10+ mentions |
UNC Joint Vector Laboratories (RRID:SCR_002448) | UNC Vector Core | access service resource, core facility, service resource | Core facility to access a comprehensive range of resources and services for gene transfer research including vector production services for research, preclinical and clinical materials. Services include: * Adeno-associated Virus (AAV) Custom Production; * AAV In-Stock Aliquots: Reporters, Deisseroth, Boyden, Roth, Uchida, Shah; * Lentivirus Custom Production | vector, clinical, gene transfer, preclinical, viral vector, adeno-associated virus | has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA | Restricted | SciRes_000117, SciRes_000124 | http://genetherapy.unc.edu/services.htm | SCR_002448 | UNC Gene Therapy Center Joint Vector Laboratories, UNC Gene Therapy Center Vector Core, University of North Carolina Vector Core | 2026-09-12 01:03:13 | 29 | ||||||
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Clinical Islet Transplantation Study Resource Report Resource Website 1+ mentions |
Clinical Islet Transplantation Study (RRID:SCR_001515) | CIT Study | clinical trial, resource | Network of centers to conduct studies of islet transplantation in patients with type 1 diabetes to improve the safety and long-term success of methods for transplanting islets. It is the aim of this trial to improve methods of isolating islets, to improve techniques for the administering those transplanted islets; and to develop approaches to minimize the toxic effects of immunosuppressive drugs required for transplantation. | islet transplantation, islet, insulin, beta cell, pancreas, autoimmune, clinical | is listed by: NIDDK Information Network (dkNET) | Type 1 diabetes, Diabetes | NIDDK U01DK070431 | Free, Freely available | nlx_152840 | SCR_001515 | Clinical Islet Transplantation Trial, Islet Transplantation Trials for Type 1 Diabetes | 2026-09-12 01:03:12 | 5 | |||||
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RiVuR Resource Report Resource Website 1+ mentions |
RiVuR (RRID:SCR_001539) | RIVUR | clinical trial, resource | Multicenter, randomized, double-blind, placebo-controlled trial is designed to determine whether daily antimicrobial prophylaxis is superior to placebo in preventing recurrence of urinary tract infection (UTI) in children with vesicoureteral reflux (VUR). The basic eligibility criteria are: (1) age at randomization of at least 2 months, but less than 6 years, (2) a diagnosed first febrile or symptomatic UTI within 42 days prior to randomization that was appropriately treated, and (3) presence of Grade I-IV VUR based on voiding cystourethrogram (VCUG). Patients will be randomly assigned to treatment for 2 years with daily antimicrobial prophylaxis (trimethoprim-sulfamethoxazole) or placebo. The study is designed to recruit 600 children (approximately 300 in each treatment group) over an 18-24 month period. The primary endpoint is recurrence of UTI. In addition, patients will be evaluated for secondary endpoints related to renal scarring and antimicrobial resistance. Scarring will be determined based on renal scintigraphy by 99mTc dimercaptosuccinic (DMSA) scan. Quality of life, compliance, safety parameters, utilization of health resources, and change in VUR will be assessed periodically throughout the study. | child, antimicrobial prophylaxis, placebo, antibiotic, renal scarring, pediatric, trimethoprim-sulfamethoxazole, intervention, kidney, antibiotic resistance, young human, infant, bibliography, clinical, trimethoprim, sulfamethoxazole |
is listed by: ClinicalTrials.gov is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA |
Vesico-ureteral reflux, Urinary tract infection | NIDDK | PMID:19570724 PMID:19018048 PMID:18076937 PMID:19018047 PMID:19086141 |
Free, Freely available | nlx_152848 | http://www.cscc.unc.edu/rivur/ | SCR_001539 | Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR), Randomized Intervention for Children with Vesicoureteral Reflux, Randomized Intervention for Vesicoureteral Reflux | 2026-09-12 01:03:12 | 1 | |||
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National Gene Vector Biorepository Resource Report Resource Website 10+ mentions |
National Gene Vector Biorepository (RRID:SCR_004760) | NGVB | access service resource, core facility, service resource | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 11, 2023. Archiving services, insertional site analysis, pharmacology and toxicology resources, and reagent repository for academic investigators and others conducting gene therapy research. Databases and educational resources are open to everyone. Other services are limited to gene therapy investigators working in academic or other non-profit organizations. Stores reserve or back-up clinical grade vector and master cell banks. Maintains samples from any gene therapy related Pharmacology or Toxicology study that has been submitted to FDA by U.S. academic investigator that require storage under Good Laboratory Practices. For certain gene therapy clinical trials, FDA has required post-trial monitoring of patients, evaluating clinical samples for evidence of clonal expansion of cells. To help academic investigators comply with this FDA recommendation, the NGVB offers assistance with clonal analysis using LAM-PCR and LM-PCR technology. | gene therapy, clinical trial, testing, insertion site, gene, clinical, vector, cell line, pharmacology, toxicology, clonal analysis, FASEB list |
is related to: NIDDK Information Network (dkNET) is related to: Phoenix has parent organization: Indiana University School of Medicine; Indiana; USA is parent organization of: NGVB SeqMap Database is parent organization of: NGVB Toxicology Database |
NCRR ; NHLBI |
PMID:31910049 | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_76398 | http://www.ngvl.org/, https://www.ngvbcc.org/Home.action | SCR_004760 | 2026-09-12 01:03:15 | 33 | |||||
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Center for Magnetic Resonance Research Resource Report Resource Website 1+ mentions |
Center for Magnetic Resonance Research (RRID:SCR_003148) | CMRR | access service resource, biomedical technology research center, service resource, training resource | Biomedical technology research center that focuses on development of unique magnetic resonance (MR) imaging and spectroscopy methodologies and instrumentation for the acquisition of structural, functional, and biochemical information non-invasively in humans, and utilizing this capability to investigate organ function in health and disease. The distinctive feature of this resource is the emphasis on ultrahigh magnetic fields (7 Tesla and above), which was pioneered by this BTRC. This emphasis is based on the premise that there exists significant advantages to extracting biomedical information using ultrahigh magnetic fields, provided difficulties encountered by working at high frequencies corresponding to such high field strengths can be overcome by methodological and engineering solutions. This BTRC is home to some of the most advanced MR instrumentation in the world, complemented by human resources that provide unique expertise in imaging physics, engineering, and signal processing. No single group of scientists can successfully carry out all aspects of this type of interdisciplinary biomedical research; by bringing together these multi-disciplinary capabilities in a synergistic fashion, facilitating these interdisciplinary interactions, and providing adequate and centralized support for them under a central umbrella, this BTRC amplifies the contributions of each of these groups of scientists to basic and clinical biomedical research. Collectively, the approaches and instrumentation developed in this BTRC constitute some of the most important tools used today to study system level organ function and physiology in humans for basic and translational research, and are increasingly applied world-wide. CMRR Faculty conducts research in a variety of areas including: * High field functional brain mapping in humans; methodological developments, mechanistic studies, and neuroscience applications * Metabolism, bioenergetics, and perfusion studies of human pathological states (tumors, obesity, diabetes, hepatic encephalopathy, cystic fibrosis, and psychiatric disorders) * Cardiac bioenergetics under normal and pathological conditions * Automated magnetic field shimming methods that are critical for spectroscopy and ultrafast imaging at high magnetic fields * Development of high field magnetic resonance imaging and spectroscopy techniques for anatomic, physiologic, metabolic, and functional studies in humans and animal models * Radiofrequency (RF) pulse design based on adiabatic principles * Development of magnetic resonance hardware for high fields (e.g. RF coils, pre-amplifiers, digital receivers, phased arrays, etc.) * Development of software for data analysis and display for functional brain mapping. | mri, imaging, magnetic resonance spectroscopy, clinical, core facility, in vivo, brain mapping | has parent organization: University of Minnesota Twin Cities; Minnesota; USA | NCRR ; NIH Blueprint for Neuroscience Research ; NIBIB ; W. M. Keck Foundation |
Free, Freely available | nif-0000-00563 | SCR_003148 | NMR Imaging and Localized Spectroscopy | 2026-09-12 01:03:13 | 5 | ||||||
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Piedmont Health Survey of the Elderly Resource Report Resource Website |
Piedmont Health Survey of the Elderly (RRID:SCR_006349) | PHSE | data or information resource, data set | Data set of a follow-up study (one of four Established Populations for Epidemiologic Studies of the Elderly - EPESE) that obtains information on four primary outcome variables (cognitive status, depression, functional status, and mortality) and four primary independent variables (social support, social class, social location, and chronic illness); and examines the relationships between social factors and chronic disease on the one hand and health outcomes on the other. This data set complements the other three sites providing a population which is both urban and rural and contains approximately equal numbers of black and white participants across a broad socioeconomic base. The Duke site was originally funded by the NIA Epidemiology, Demography and Biometry Program (EDBP) to complete seven waves of data collection (three in-person and four telephone interviews) in order to examine the health of a sample of 4,162 persons aged 65+, and factors that influence their health and use of health services. The cohort was originally interviewed in 1986/87 and followed annually for 6 years thereafter. The study design consisted of a random stratified household sample with an over-sampling of blacks. Questionnaire topics include the following: Demographics, Alcohol Use, Independence, Health condition, Cognition, Personal mastery, Health Service Utilization, Activity of daily living, Social Support, Hearing and Vision, Incontinence, Social Interaction, Weight and Height, Smoking, Religion, Nutrition, Life Satisfaction, Self Esteem, Sleep, Medications, Economic Status, Depression, Life Changes, Blood pressure. National Death Index files have been searched and death certificates obtained for the members of this study. Sample members have been matched with Medicare Part A files to obtain information on hospitalizations, and will be matched on Medicare Part B (outpatient) files. Data from the first wave of the survey is in the public domain and can be obtained from NACDA or from the National Archives, Center for Electronic Records in Washington, DC. * Dates of Study: 1996-1997 * Study Features: Longitudinal, Oversampling * Sample Size: 1986-1988: 4,162 Links: * ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/02744 * National Archives: http://www.archives.gov/research/electronic-records/ | late adult human, african-american, caucasian, interview, questionnaire, health, health service utilization, cognitive status, functional status, mortality, social support, social class, social location, chronic illness, social factor, chronic disease, health outcome, questionnaire, demographics, alcohol use, independence, health condition, cognition, personal mastery, activity of daily living, social support, hearing, vision, incontinence, social interaction, weight, height, smoking, religion, nutrition, life satisfaction, self esteem, sleep, medication, economic status, depression, life change, blood pressure, survey, chronic illness, disease, epidemiology, hospitalization, long term care, mortality rate, risk factor, death, clinical |
is listed by: Inter-university Consortium for Political and Social Research (ICPSR) is related to: Established Populations for Epidemiologic Studies of the Elderly has parent organization: Duke University School of Medicine; North Carolina; USA has parent organization: National Archive of Computerized Data on Aging (NACDA) |
Aging, All noninstitutionalized persons 65 years of age and older (at baseline, 1986-1987) in Durham, Warren, Vance, Granville, And Franklin counties in north central North Carolina | NIA 1-R01 AG12765 | Public: This product is distributed as a CD-ROM. | nlx_152068 | SCR_006349 | Piedmont Health Survey of the Elderly (PHSE) Ten-Year Follow-up of the North Carolina EPESE | 2026-09-12 01:03:16 | 0 |
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