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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.uab.edu/medicine/obriencenter/
Research center for kidney research, specifically acute kidney injury. It supports shared core facilities, encourages collaboration between investigators from different backgrounds and disciplines whose shared interest is in kidney research, and provides intellectual resources and infrastructure.
Proper citation: UAB-UCSD Core Center for Acute Kidney Injury Research (RRID:SCR_015282) Copy
http://chicagodiabetesresearch.org
Center to improve the lives of people with diabetes and people at risk for diabetes through prevention, improved diabetes care, and community empowerment.
Proper citation: Chicago Center for Diabetes Translation Research (RRID:SCR_015179) Copy
http://norccentral.org/centers/colorado/
Research center that aims to provide an infrastructure to support ongoing nutrition and obesity research by providing measurements and expertise. It also aims to promote interdisciplinary collaborative, vertically integrated research among members of the Colorado research community, as well as translate basic and clinical research into programs to improve health and wellness and reduce obesity in the community.
Proper citation: University of Colorado Anschutz Medical Campus Nutrition and Obesity Research Center (RRID:SCR_015451) Copy
Research center for obesity investigators which aims to provide researchers with infrastructure, expertise, and training to facilitate improved data integration, analysis and modeling from properly designed basic, clinical, and population-based studies in obesity and metabolism-related diseases.
Proper citation: University of Michigan Nutrition and Obesity Research Center (RRID:SCR_015457) Copy
http://www.einstein.yu.edu/centers/diabetes-translational-research/
Center designed to increase collaboration and enhance communication among diabetes researchers from multiple institutions and diverse disciplines
Proper citation: New York Regional Center for Diabetes Translation Research (RRID:SCR_015174) Copy
http://www.utsouthwestern.edu/research/core-facilities/obrien-kidney/
Center whose goal is to generate new animal models to study the pathogenesis and treatment of human kidney diseases and their cardiovascular complications, accelerate the clinical application of discoveries made in renal basic science laboratories, and provide investigators with specialized tools and expertise to study kidney development, physiology, and pathophysiology.
Proper citation: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center (RRID:SCR_015293) Copy
Research center that aims to understand the causal factors underlying nutrition and obesity-related health problems and the generation and evaluation of evidence on their consequences, prevention, and alleviation.
Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center (RRID:SCR_015418) Copy
https://www.cincinnatichildrens.org/research/divisions/n/nephrology/center-of-excellence
Center whose goal is to support basic, translational, and clinical research on critical pediatric kidney diseases by focusing on Acute Kidney Injury, Nephrotic Syndrome, and Lupus Nephritis.
Proper citation: Pediatric Centers of Excellence in Nephrology at Cincinnati Children's Hospital Medical Center (RRID:SCR_015302) Copy
https://www.uab.edu/medicine/gastroenterology/research/mhic
Research center which investigates the interaction between microbes and mucosal tissues in humans. It provides three core facilities for research: the Genetically-Defined Microbe Core, the Molecular Pathology and Human Cell/Tissue Core, and the Gnotobiotic and Genetically-Engineered Mouse Core.
Proper citation: Mucosal HIV and Immunobiology Center (RRID:SCR_015261) Copy
https://www.niddk.nih.gov/research-funding/research-programs/kidney-disease-centers
A portal with detailed information about various research centers that focus on kidney disease and translational research funded by NIDDK.
Proper citation: Polycystic Kidney Disease Research and Translation Centers (RRID:SCR_015305) Copy
http://www.uab.edu/medicine/hrfdcc/
Center that focuses on understanding the causes of Cystic Kidney Disease and other related disorder and the development of new therapeutic strategies.
Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center (RRID:SCR_015311) Copy
http://www.baltimorepkdcenter.org/
Center for research in polycystic kidney disease (PKD) with collaboration by international investigators. The center has several cores, including biomedical cores for antibody validation and cell cultures, educationa programs, and pilot programs for new projects.
Proper citation: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center (RRID:SCR_015315) Copy
Center that concentrates on the common, adult form of the disease, autosomal dominant PKD (ADPKD). The services provided focus on understanding the genetic basis of disease, more accurately monitoring disease progression and improving prognostics, and employing model systems to explore pathogenesis and conduct preclinical testing.
Proper citation: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester (RRID:SCR_015313) Copy
https://www.niddk.nih.gov/research-funding/research-programs/kidney-disease-centers
Research program whose aim is to make state-of-the art technologies and resources accessible to a broad spectrum of investigators pursuing studies in kidney research areas.
Proper citation: O'Brien Kidney Centers (RRID:SCR_015270) Copy
https://labnodes.vanderbilt.edu/drtc
University-affiliated center that facilitates the discovery, application, and translation of scientific knowledge to improve the lives of people with diabetes.
Proper citation: Vanderbilt Diabetes Research and Training Center (RRID:SCR_015153) Copy
https://www.uab.edu/medicine/cysticfibrosis/
Research center that maintains core facilities available for studies of cell biology, ion transport, and translational aspects of cystic fibrosis research.
Proper citation: Gregory Fleming James Cystic Fibrosis Research Center (RRID:SCR_015392) Copy
http://depts.washington.edu/cfrtc/
Research center that aims to provide resources and expertise to expedite development of potential new therapeutic approaches to correct dysfunctional CFTR and its secondary consequences, enhance understanding of evolving bacterial ecosystems and resultant host response in CF gastrointestinal and respiratory tracts, and how these interactions impact health. It also aims to develop improved assays, new drug screening assays, biomarkers and improved clinical outcome measures, as well as to better understand the metabolic and inflammatory consequences of CFTR dysfunction.
Proper citation: Cystic Fibrosis Center - University of Washington (RRID:SCR_015401) Copy
http://ccb.jhu.edu/software/hisat2/index.shtml
Graph-based alignment of next generation sequencing reads to a population of genomes.
Proper citation: HISAT2 (RRID:SCR_015530) Copy
An image processing program running under Windows suitable for such tasks as tensor calculation, color mapping, fiber tracking, and 3D visualization. Most of operations can be done with only a few clicks. This tool evolved from DTI Studio. Tools in the program can be grouped in the following way: * Image Viewer * Diffusion Tensor Calculations * Fiber Tracking and Editing * 3D Visualization * Image File Management * Region of Interesting (ROI) Drawing and Statistics * Image Registration
Proper citation: MRI Studio (RRID:SCR_001398) Copy
http://bmsr.usc.edu/software/pneuma/
A set of modules that are used to simulate the autoregulation of the cardiovascular and respiratory systems under conditions of changing sleep-wake state and a variety of physiological and pharmacological interventions. It models the dynamic interactions that take place among the various component mechanisms, including those involved in the chemical control of breathing, heart rate, and blood pressure, as well as the effects of changes in the sleep-wake state and arousal from sleep. PNEUMA includes the autonomic control of the cardiovascular system, chemoreflex and state-related control of breath-to-breath ventilation, state-related and chemoreflex control of upper airway potency, as well as respiratory and circulatory mechanics. The model is capable of simulating the cardiorespiratory responses to sleep onset, arousal, continuous positive airway pressure, the administration of inhaled carbon dioxide and oxygen, Valsalva and Mueller maneuvers, and Cheyne-Stokes respiration during sleep. In PNEUMA 3.0, we have extended the existing integrative model of respiratory, cardiovascular, and sleepwake state control, to incorporate a sub-model of glucoseinsulinfatty acid regulation. The extended model is capable of simulating the metabolic control of glucoseinsulin dynamics and its interactions with the autonomic nervous system. The interactions between autonomic and metabolic control include the circadian regulation of epinephrine secretion, epinephrine regulation on dynamic fluctuations in glucose and free fatty acids in plasma, metabolic coupling among tissues and organs mediated by insulin and epinephrine, as well as the effect of insulin on peripheral vascular sympathetic activity. This extended model represents a starting point from which further in silico investigations into the interaction between the autonomic nervous system and the metabolic control system can proceed. Features in PNEUMA 3.0 * Incorporates metabolic component based on prior models of glucose-insulin regulation and free fatty acid (FFA) regulation. * Changes in sympathetic activity from the autonomic portion of PNEUMA produce changes in epinephrine output, which in turn affects the metabolic sub-model. * Inputs from the dietary intake of glucose and external interventions, such as insulin injections, have also been incorporated. * Also incorporated is autonomic feedback from the metabolic component to the rest of PNEUMA: changes in insulin level lead to changes in sympathetic tone. System Requirements: PNEUMA requires Matlab R2007b or higher with the accompanying version of Simulink to be installed on your computer.
Proper citation: PNEUMA (RRID:SCR_001391) Copy
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