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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://amigo.geneontology.org/
Web tool to search, sort, analyze, visualize and download data of interest. Along with providing details of the ontologies, gene products and annotations, features a BLAST search, Term Enrichment and GO Slimmer tools, the GO Online SQL Environment and a user help guide.Used at the Gene Ontology (GO) website to access the data provided by the GO Consortium. Developed and maintained by the GO Consortium.
Proper citation: AmiGO (RRID:SCR_002143) Copy
Online database for finding and analyzing syntenic regions across multiple genomes and measuring the extent of genome rearrangement using reversal distance as a measure.
Proper citation: Cinteny (RRID:SCR_002147) Copy
https://github.com/TGAC/miso-lims
Open source software for a Laboratory Information Management System (LIMS) for NGS sequencing centres.
Proper citation: miso-lims (RRID:SCR_002259) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowFit.html
A Bioconductor package designed to perform quantitative analysis of cell proliferation in tracking dye-based experiments. The package uses an R implementation of the Levenberg-Marquardt algorithm (minpack.lm) to fit a set of peaks (corresponding to different generations of cells) over the proliferation-tracking dye distribution in a FACS experiment.
Proper citation: flowFit (RRID:SCR_002286) Copy
http://www.bioconductor.org/packages/2.13/bioc/html/spliceR.html
An easy-to-use R package for classification of alternative splicing and prediction of coding potential from RNA-seq data.
Proper citation: spliceR (RRID:SCR_002280) Copy
A comprehensive collection of experimentally determined and computationally predicted CCCTC-binding factor (CTCF) binding sites (CTCFBS) from the literature. The database is designed to facilitate the studies on insulators and their roles in demarcating functional genomic domains. The CTCFBS Prediction Tool allows users to scan sequences for the single best match to CTCF position weight matrices. Currently (March 2014), the database contains almost 15 million experimentally determined CTCF binding sites across several species. CTCF binding sites were collected from published papers containing CTCF binding sites identified using ChIPSeq or similar methods, data from the ENCODE project, and a set of approximately 100 manually curated binding sites identified by low-throughput experiments. Users can browse insulator sequence features, function annotations, genomic contexts including histone methylation profiles, flanking gene expression patterns and orthologous regions in other mammalian genomes. Users can also retrieve data by text search, sequence search and genomic range search.
Proper citation: CTCFBSDB (RRID:SCR_002279) Copy
http://code.google.com/p/frhit/
An efficient fragment recruitment software program for next generation sequences against microbial reference genomes. It produces similar sensitivity of BLASTN, but runs at a 100 times higher speed. The algorithm adopts a seeding heuristic strategy with overlapping k-mer hashing to locate candidate matching blocks on the reference sequences, and then apply an effective filtering within the candidate blocks to filter out blocks that do not meet the minimum criteria for containing an alignment with specified parameters. For each candidate block that passed the filter, the best matching sub-regions between a candidate block and a read are determined, and used subsequently by the banded Smith-Waterman algorithm to carry out the actual alignment efficiently, which will finally verify if this can be a valid recruitment hit.
Proper citation: FR-HIT (RRID:SCR_002181) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowPlots.html
Software for analysis plots and data class for gated flow cytometry data.
Proper citation: flowPlots (RRID:SCR_002177) Copy
http://cran.r-project.org/web/packages/metaRNASeq/
Software package for meta-analysis of RNA-seq data. This package implements two p-value combination techniques (inverse normal and Fisher methods). It also provides a vignette explaining how to combine data from multiple RNA-seq experiments.
Proper citation: metaRNASeq (RRID:SCR_002174) Copy
https://cran.r-project.org/src/contrib/Archive/demi/
R package for estimating differential expression from multiple indicators that capitalizes on the high number of concurrent measurements. It extends to various experimental designs and target categories (transcripts, genes, genomic regions) as well as small sample sizes.
Proper citation: DEMI (RRID:SCR_002291) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowCore.html
A Bioconductor software package for high throughput flow cytometry that provides S4 data structures and basic functions.
Proper citation: flowCore (RRID:SCR_002205) Copy
http://sourceforge.net/projects/mirprimer/
Software tool for automatic design of primers for PCR amplification of microRNAs using the method miR-specific RT-qPCR (Balcells, I., Cirera, S., and Busk, P.K. (2011). Specific and sensitive quantitative RT-PCR of miRNAs with DNA primers. BMC Biotechnol. 11, 70).
Proper citation: miRprimer (RRID:SCR_000480) Copy
http://sourceforge.net/projects/bait/
Software to create strand inheritance plots in data derived from the Strand-Seq sequencing protocol. The software is designed to be flexible with a range of species, and basic template folders can called to read in species-specific data.
Proper citation: BAIT (RRID:SCR_000511) Copy
http://sourceforge.net/projects/pyqpcr/
A GUI application written in python that deals with quantitative PCR (QPCR) raw data. Using quantification cycle values extracted from QPCR instruments, it uses a proven and universally applicable model to give finalized quantification resu
Proper citation: pyQPCR (RRID:SCR_000471) Copy
http://fulxie.0fees.us/?type=reference&ckattempt=1
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 1,2023. Web-based tool for evaluating and screening reference genes from extensive experimental datasets. It integrates major computational programs (geNorm, Normfinder, BestKeeper, and the comparative delta-Ct method) to compare and rank the tested candidate reference genes. Based on the rankings from each program, it assigns an appropriate weight to an individual gene and calculated the geometric mean of their weights for the overall final ranking., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: RefFinder (RRID:SCR_000472) Copy
Software tool for association study of high-dimensional microRNA expression data with repeated measures. The penalized regression model incorporates a grid search method for analyzing associations of high-dimensional microRNA expression data with repeated measures.
Proper citation: PGS (RRID:SCR_000475) Copy
http://trace.ddbj.nig.ac.jp/dor/index_e.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 6,2023. Archival database of functional genomics data generated by microarray and highly parallel new generation sequencers. Data are exchanged between ArrayExpress at EBI and DOR in common MAGE-TAB format. Supports MIAME and MINSEQE-compliant data submissions. DOR issues accession numbers, E-DORD-n to experiment and A-DORD-n to array design. DOR exchanges public data with the EBI ArrayExpress in common MAGE-TAB format. Note: At present, DOR does not accept submissions. DDBJ will announce launch of DOR when it is ready. (2013/01/31) The data can be kept private until your paper is published. You can set the hold date for a maximum of 1 year and can change it. Registered records are released according to the Data Release Policy.
Proper citation: DDBJ Omics Archive (RRID:SCR_000597) Copy
http://www.broadinstitute.org/cancer/cga/contest
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 8,2025. A software tool (and method) for estimating the amount of cross-sample contamination in next generation sequencing data.
Proper citation: ContEst (RRID:SCR_000595) Copy
https://github.com/cc2qe/speedseq
Software for a lightweight, flexible, and open source pipeline that identifies genomic variation (single nucleotide variants (SNVs), indels, and structural variants (SVs)).
Proper citation: SpeedSeq (RRID:SCR_000469) Copy
http://www.atgc-montpellier.fr/mpscan/
Web tool for index free mapping of multiple short reads on a genome.
Proper citation: MPscan (RRID:SCR_000587) Copy
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