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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
flowMerge
 
Resource Report
Resource Website
1+ mentions
flowMerge (RRID:SCR_002224) software resource Software for merging of mixture components for model-based automated gating of flow cytometry data using the flowClust framework. software package, mac os x, unix/linux, windows, r, clustering, flow cytometry is listed by: OMICtools
has parent organization: Bioconductor
PMID:20049161 Free, Available for download, Freely available OMICS_05605 SCR_002224 flowMerge - Cluster Merging for Flow Cytometry Data 2026-09-12 12:55:38 2
flowPhyto
 
Resource Report
Resource Website
flowPhyto (RRID:SCR_002183) software resource An R package that performs aggregate statistics on virtually unlimited collections of raw flow cytometry files and provides a memory efficient, parallelized solution for analyzing high-throughput flow cytometric data. software package, mac os x, unix/linux, windows, r, classification, clustering, data import, flow cytometry, quality control, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:21208987 Free, Available for download, Freely available OMICS_05606 http://www.bioconductor.org/packages/release/bioc/html/flowPhyto.html SCR_002183 flowPhyto - Methods for Continuous Flow Cytometry 2026-09-12 12:55:37 0
BEAT
 
Resource Report
Resource Website
100+ mentions
BEAT (RRID:SCR_002387) software resource Software that implements all bioinformatics steps required for the quantitative, high-resolution analysis of DNA methylation patterns from bisulfite sequencing data. standalone software, unix/linux, mac os x, windows, r, dna methylation, epigenetics, genetics, methyl-seq is listed by: OMICtools
has parent organization: Bioconductor
PMID:24618468 GNU Lesser General Public License, v3 or greater OMICS_03425 SCR_002387 BS-Seq Epimutation Analysis Toolkit, BEAT - BS-Seq Epimutation Analysis Toolkit 2026-09-12 12:55:40 130
r3Cseq
 
Resource Report
Resource Website
10+ mentions
r3Cseq (RRID:SCR_003198) r3Cseq data analysis software, data processing software, software application, software resource An R/Bioconductor package to identify chromosomal interaction regions generated by chromosome conformation capture (3C) coupled to next-generation sequencing (NGS), a technique termed 3C-seq. It performs data analysis for a number of different experimental designs, as it can analyze 3C-seq data with or without a control experiment and it can be used to facilitate data analysis for experiments with multiple replicates. The r3Cseq package provides functions to perform data normalization, statistical analysis for cis/trans interactions and visualization in order to help scientists identify genomic regions that physically interact with the given viewpoints of interest. This tool greatly facilitates hypothesis generation and the interpretation of experimental results. next-generation sequencing, genomic, interaction, chromosome conformation capture, chromosome, 3c-seq, r is listed by: OMICtools
has parent organization: University of Bergen; Bergen; Norway
has parent organization: Bioconductor
PMID:23671339 Free, Freely available OMICS_01560 SCR_003198 2026-09-12 12:55:53 24
QDNAseq
 
Resource Report
Resource Website
100+ mentions
QDNAseq (RRID:SCR_003174) software resource Software package for quantitative DNA sequencing for chromosomal aberrations providing a robust, cost-effective WGS method for DNA copy number analysis. The genome is divided into non-overlapping fixed-sized bins, number of sequence reads in each counted, adjusted with a simultaneous two-dimensional loess correction for sequence mappability and GC content, and filtered to remove spurious regions in the genome. Downstream steps of segmentation and calling are also implemented via packages DNAcopy and CGHcall, respectively. software package, unix/linux, mac os x, windows, r, copy number variation, dna-seq, genetics, genome annotation, preprocessing, quality control, sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:25236618 Free, Available for download, Freely available OMICS_05902, biotools:qdnaseq https://github.com/ccagc/QDNAseq, https://bio.tools/qdnaseq SCR_003174 QDNAseq - Quantitative DNA sequencing for chromosomal aberrations 2026-09-12 12:55:53 168
LaSSO
 
Resource Report
Resource Website
100+ mentions
LaSSO (RRID:SCR_003418) software resource An R script that creates a FASTA database containing all possible lariat signatures from a given set of introns. standalone software, r, FASEB list is listed by: OMICtools PMID:24709818 Free, Available for download, Freely available OMICS_04622 SCR_003418 Lariat Sequence Site Origin 2026-09-12 12:55:57 224
Kdetrees
 
Resource Report
Resource Website
Kdetrees (RRID:SCR_004522) software resource R package using a non-parametric method for estimating distributions of phylogenetic trees, with the goal of identifying trees that are significantly different from the rest of the trees in the sample. applet, mac os x, unix/linux, windows, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: CRAN
PMID:24764459 GNU General Public License, v2 biotools:kdetrees, OMICS_04172 https://github.com/grady/kdetrees, https://bio.tools/kdetrees SCR_004522 kdetrees: Nonparametric method for identifying discordant phylogenetic trees 2026-09-12 12:56:14 0
g:Profiler
 
Resource Report
Resource Website
1000+ mentions
g:Profiler (RRID:SCR_006809) analysis service resource, data access protocol, data analysis service, production service resource, service resource, software resource, web service Web server for functional enrichment analysis and conversions of gene lists. Web based tool for functional profiling of gene lists from large scale experiments. Has web interface with powerful visualization. Used for analyzing data from any organism. gene, high-throughput, genomics, visualization, statistical analysis, slimmer-type tool, term enrichment, protein interaction, functional similarity, analysis, coexpression, gene id, network enrichment analysis, orthology mapping, genomic locus, ontology or annotation visualization, other analysis, ortholog, functional profile, gene list, ontology, pathway, transcription factor, microrna, regulatory motif, protein-protein interaction, biomolecule, gene expression, gene, homology, single nucleotide polymorphism, dna polymorphism, chromosome, network analysis, disease gene, r is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
is related to: Ensembl
is related to: Ensembl Genomes
has parent organization: BIIT - Bioinformatics Algorithmics and Data Mining Group
works with: gProfiler2
Estonian Research Council grants ;
European Regional Development Fund for CoE of Estonian ICT research EXCITE projects
PMID:21646343
PMID:17478515
PMID:31066453
Free, Freely available OMICS_02223, nif-0000-31975 SCR_006809 G:Profiler, g:profiler, gProfiler 2026-09-12 12:56:46 2310
BARS
 
Resource Report
Resource Website
10+ mentions
BARS (RRID:SCR_009123) BARS software application, software resource Software application that is a statistical method that bridges the gap between single-locus and haplotype-based tests of association. It is based on the non-parametric regression techniques embodied by Bayesian Adaptive Regression Splines. (entry from Genetic Analysis Software), THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, r, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE nlx_154204, biotools:bars, nlx_154228, SCR_009106 https://bio.tools/bars SCR_009123 Bayesian Adaptive Regression Splines 2026-09-12 12:57:11 39
aLFQ
 
Resource Report
Resource Website
10+ mentions
aLFQ (RRID:SCR_005925) software resource An R-package for estimating absolute protein quantities from label-free liquid chromatography tandem mass spectrometry (LC-MS/MS) proteomics data. It supports the commonly used absolute label-free protein abundance estimation methods (TopN, iBAQ, APEX, NSAF and SCAMPI) for LC-MS/MS proteomics data, quantifying on either MS1-, MS2-levels or spectral counts together with validation algorithms to enable automated data analysis and error estimation. Specifically, they used Monte-carlo cross-validation and bootstrapping for model selection and imputation of proteome-wide absolute protein quantity estimation. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: CRAN
PMID:24753486 GNU General Public License, v3 or greater OMICS_04053 SCR_005925 aLFQ: An R-package for estimating absolute protein quantities from label-free LC-MS/MS proteomics data 2026-09-12 12:56:33 22
Cascade
 
Resource Report
Resource Website
50+ mentions
Cascade (RRID:SCR_005861) Cascade software resource R software package to study, predict and simulate the diffusion of a signal through a temporal gene network. It predicts changes in gene expressions after a biological perturbation in the network and provides graphical outputs that allow monitoring the spread of a signal through the network., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. r, windows, gene expression, perturbation, network, diffusion, signal, temporal gene network, gene regulatory network, gene, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Strasbourg; Strasbourg; France
PMID:24307703 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02249, biotools:cascade http://www-math.u-strasbg.fr/genpred/spip.php?rubrique4, https://bio.tools/cascade SCR_005861 2026-09-12 12:56:32 92
IQRray
 
Resource Report
Resource Website
1+ mentions
IQRray (RRID:SCR_006057) IQRray software resource Software based on evolutionary conservation of expression profiles, implemented in R, for identification of poor quality arrays in dataset composed of arrays from many independent experiments. r, affymetrix, microarray, quality control, evolutionary conservation, expression profile, probe is listed by: OMICtools
has parent organization: University of Lausanne; Lausanne; Switzerland
PMID:24451627 Free, Public OMICS_02244 SCR_006057 2026-09-12 12:56:34 2
YuGene
 
Resource Report
Resource Website
10+ mentions
YuGene (RRID:SCR_006023) software resource Software providing a simple method for comparison of gene expression generated across different experiments, and on different platforms; that does not require global renormalization, and is not restricted to comparison of identical probes. YuGene works on a range of microarray dataset distributions, such as between manufacturers. The resulting output allows direct comparisons of gene expression between experiments and experimental platforms. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: CRAN
PMID:24667244 GNU General Public License, v2, v3 OMICS_04030 SCR_006023 YuGene: A simple approach to scale gene expression data derived from different platforms for integrated analyses 2026-09-12 12:56:34 16
CAFE
 
Resource Report
Resource Website
500+ mentions
CAFE (RRID:SCR_005983) CAFE software resource R software package for the detection of gross chromosomal abnormalities from gene expression microarray data. affymetrix, r, chromosomal abnormality, gene expression, microarray, chromosome, linux, windows is listed by: OMICtools
has parent organization: Bitbucket
PMID:24451624 GNU General Public License, v3, Acknowledgement requested OMICS_02245 SCR_005983 2026-09-12 12:56:34 883
RUVSeq
 
Resource Report
Resource Website
100+ mentions
RUVSeq (RRID:SCR_006263) software resource Software package that implements the remove unwanted variation (RUV) methods for the normalization of RNA-Seq read counts between samples. software package, unix/linux, mac os x, windows, r, differential expression, preprocessing, rna-seq is listed by: OMICtools
has parent organization: Bioconductor
PMID:25150836 Artistic License, v2 OMICS_05652 SCR_006263 RUVSeq: Remove Unwanted Variation from RNA-Seq Data 2026-09-12 12:56:37 481
AbsCN-seq
 
Resource Report
Resource Website
1+ mentions
AbsCN-seq (RRID:SCR_006409) AbsCN-seq software resource Statistical software to estimate tumor purity, ploidy and absolute copy numbers from next generation sequencing data. r, statistics, purity, ploidy, absolute copy number, next-generation sequencing is listed by: OMICtools
has parent organization: University of California at San Diego; California; USA
Tumor, Cancer PMID:24389661 Free, Public OMICS_02202 SCR_006409 2026-09-12 12:56:39 7
CAMERA - Collection of annotation related methods for mass spectrometry data
 
Resource Report
Resource Website
1+ mentions
CAMERA - Collection of annotation related methods for mass spectrometry data (RRID:SCR_002466) CAMERA software resource A Bioconductor package integrating algorithms to extract compound spectra, annotate isotope and adduct peaks, and propose the accurate compound mass even in highly complex data. standalone software, mac os x, unix/linux, windows, r, spectra, extraction, annotation, liquid chromatography, mass spectrometry, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:22111785 Free, Available for download, Freely available biotools:camera, OMICS_03366 https://bio.tools/camera SCR_002466 CAMERA - Collection of annotation related methods for mass spectrometry data 2026-09-12 12:55:41 4
Iterative Signature Algorithm
 
Resource Report
Resource Website
Iterative Signature Algorithm (RRID:SCR_002327) isa2, ISA software resource A biclustering algorithm that finds modules in an input matrix. A module or bicluster is a block of the reordered input matrix. standalone software, mac os x, unix/linux, windows, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: CRAN
PMID:12689096 Creative Commons Attribution-NonCommercial-ShareAlike License, v3 biotools:isa, OMICS_03487 https://bio.tools/isa SCR_002327 isa2: The Iterative Signature Algorithm 2026-09-12 12:55:39 0
ExomeDepth
 
Resource Report
Resource Website
100+ mentions
ExomeDepth (RRID:SCR_002663) software resource Software that calls copy number variants (CNVs) from targeted sequence data, typically exome sequencing experiments designed to identify the genetic basis of Mendelian disorders. software package, unix/linux, mac os x, windows, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: CRAN
PMID:22942019 Free, Available for download, Freely available OMICS_05443, biotools:exomedepth https://bio.tools/exomedepth SCR_002663 2026-09-12 12:55:44 295
MethylAid
 
Resource Report
Resource Website
50+ mentions
MethylAid (RRID:SCR_002659) software resource Software for visual and interactive quality control of large Illumina 450k data sets. Bad quality samples are detected using sample-dependent and sample-independent controls present on the array and user adjustable thresholds. In depth exploration of bad quality samples can be performed using several interactive diagnostic plots of the quality control probes present on the array. Furthermore, the impact of any batch effect provided by the user can be explored. software package, illumina, mac os x, unix/linux, windows, r, dna methylation, gui, methylation array, microarray, quality control, two channel, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:25147358 Free, Available for download, Freely available biotools:methylaid, OMICS_05457 http://www.bioconductor.org/packages/release/bioc/html/MethylAid.html, http://shiny.bioexp.nl/MethylAid/, https://bio.tools/methylaid SCR_002659 MethylAid - Visual and interactive quality control of large Illumina 450k data sets, MethylAid: Visual and interactive quality control of large Illumina 450k data sets 2026-09-12 12:55:44 68

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