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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_3787
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Caution: We believe that the clone called RKO-E6 by PubMed=7700629 is the clone RC10-1 originally described by PubMed=8387205 but it is also possible that it is RKO RC10-2 (Cellosaurus=CVCL_E7ET) or RKO RC10-3 (Cellosaurus=CVCL_E7EU) or RKO RC10-4 (Cellosaurus=CVCL_E7EV).
Proper citation: RRID:CVCL_3787 Copy
https://web.expasy.org/cellosaurus/CVCL_2270
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Caution: Could be identical to HTK- (Cellosaurus=CVCL_2522)., Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2270 Copy
Possibly Contaminated
https://web.expasy.org/cellosaurus/CVCL_0308
Organism: Homo sapiens (Human)
Disease: Nasopharyngeal carcinoma
Category: Cancer cell line
Comments: Virology: EBV-negative in established line., Problematic cell line: Possibly contaminated. The STR profile is very similar to that of the HeLa cell line and almost identical to that of HNE-2 (Cellosaurus=CVCL_FA07)..
Proper citation: RRID:CVCL_0308 Copy
https://web.expasy.org/cellosaurus/CVCL_1695
Organism: Homo sapiens (Human)
Disease: Adrenal gland neuroblastoma
Category: Cancer cell line
Comments: Biotechnology: Used in a bioassay to measure botulinum toxin serotype A (BoNT/B) activity. Together with the monoclonal antibody produced by hybridoma 2E2A6 (Cellosaurus=CVCL_RA98)., Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-164, RRID:CVCL_1695 Copy
https://web.expasy.org/cellosaurus/CVCL_1695
Organism: Homo sapiens (Human)
Disease: Adrenal gland neuroblastoma
Category: Cancer cell line
Comments: Biotechnology: Used in a bioassay to measure botulinum toxin serotype A (BoNT/B) activity. Together with the monoclonal antibody produced by hybridoma 2E2A6 (Cellosaurus=CVCL_RA98)., Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1695 Copy
Misidentified
https://web.expasy.org/cellosaurus/CVCL_AT69
Organism: Homo sapiens (Human)
Category: Undefined cell line type
Comments: From: Ontario Cancer Institute (OCI); Toronto; Canada., Problematic cell line: Misidentified. This cell line was mistakenly distributed by OCI to a number of groups as being OCI-Ly-3 (Cellosaurus=CVCL_8800). The real identity of this cell line is not known. From personal communication of Neve, Richard M..
Proper citation: RRID:CVCL_AT69 Copy
https://web.expasy.org/cellosaurus/CVCL_1559
Organism: Homo sapiens (Human)
Disease: Minimally invasive lung adenocarcinoma
Category: Cancer cell line
Comments: Caution: NCI-H358 and NCI-H358M (Cellosaurus=CVCL_JA53) could be identical., Population: Caucasian., Part of: NCI RAS program mutant KRAS cell line panel., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1559 Copy
Misclassified Discontinued
https://web.expasy.org/cellosaurus/CVCL_2991
Organism: Homo sapiens (Human)
Category: Undefined cell line type
Comments: Population: Japanese., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Misclassified. Originally thought to be a myeloma cell line and to be a sister line to KMS-21-PE (Cellosaurus=CVCL_A445) but this does not seem to be the case (PubMed=12592342; PubMed=20143388)..
Proper citation: RRID:CVCL_2991 Copy
Misidentified/Contaminated
https://web.expasy.org/cellosaurus/CVCL_1402
Organism: Homo sapiens (Human)
Disease: Melanoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Misidentified/contaminated. Shown to be identical to MEL-Wei. This cell line was reported to be isogenic with LCL-Ho (Cellosaurus=CVCL_1868) but it does not have the same STR profile (PubMed=10508494; PubMed=20143388). According to DSMZ ACC-62 it is a human female cell line..
Proper citation: RRID:CVCL_1402 Copy
Partially Misidentified
https://web.expasy.org/cellosaurus/CVCL_5594
Organism: Homo sapiens (Human)
Disease: Breast carcinoma
Category: Cancer cell line
Comments: Part of: JWGray breast cancer cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Partially misidentified. For a period of time Asterand (now BioIVT) mistakenly distributed SUM149PT (Cellosaurus=CVCL_3422) under the designation of SUM229PE. This leads to the publication of a STR profile (PubMed=25877200) which was almost identical to that of SUM149PT.., Group: Triple negative breast cancer (TNBC) cell line.
Proper citation: RRID:CVCL_5594 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_2787
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Caution: FLC-4 (Cellosaurus=CVCL_D204) is often stated to be synonymous with JHH-4, but a FLC-4 patent reference (Patent=US5804441) seems to indicate that it is derived from JHH-4 and has a different karyotype., Population: Japanese., Part of: MD Anderson Cell Lines Project., Part of: Liver Cancer Model Repository (LIMORE)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2787 Copy
Misidentified Discontinued
https://web.expasy.org/cellosaurus/CVCL_0022
Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 3., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Misidentified. This cell line is not the original glioblastoma cell line established in 1968 at the University of Uppsala. As described in PubMed=27582061 it is most probably also a glioblastoma cell line but whose origin is unknow. See U-87MG Uppsala (Cellosaurus=CVCL_GP63) for the original U-87MG cell line..
Proper citation: RRID:CVCL_0022 Copy
https://web.expasy.org/cellosaurus/CVCL_2420
Organism: Homo sapiens (Human)
Disease: High grade ovarian serous adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: TCGA-110-CL cell line panel., Part of: OCCP ovarian cancer cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2420 Copy
https://web.expasy.org/cellosaurus/CVCL_2417
Organism: Homo sapiens (Human)
Disease: Lung small cell carcinoma
Category: Cancer cell line
Proper citation: ECACC Cat# 96020749, RRID:CVCL_2417 Copy
https://web.expasy.org/cellosaurus/CVCL_2423
Organism: Homo sapiens (Human)
Disease: Ovarian carcinoma
Category: Cancer cell line
Comments: Part of: OCCP ovarian cancer cell line panel.
Proper citation: RRID:CVCL_2423 Copy
Misclassified
https://web.expasy.org/cellosaurus/CVCL_2010
Organism: Homo sapiens (Human)
Disease: Ovarian small cell carcinoma, hypercalcemic type
Category: Cancer cell line
Comments: Characteristics: Because it conserved a number of properties of normal human granulosa cells, it is used in the investigation of such cell type., Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Misclassified. Originally thought to be an ovarian granulosa cell tumor but seems to be a small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) (PubMed=33328126)..
Proper citation: RRID:CVCL_2010 Copy
https://web.expasy.org/cellosaurus/CVCL_2413
Organism: Homo sapiens (Human)
Disease: Lung squamous cell carcinoma
Category: Cancer cell line
Comments: Omics: Transcriptome analysis by microarray., Omics: DNA methylation analysis., Omics: Deep quantitative proteome analysis., Omics: Deep exome analysis., Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: ECACC Cat# 96020744, RRID:CVCL_2413 Copy
https://web.expasy.org/cellosaurus/CVCL_2417
Organism: Homo sapiens (Human)
Disease: Lung small cell carcinoma
Category: Cancer cell line
Proper citation: RRID:CVCL_2417 Copy
https://web.expasy.org/cellosaurus/CVCL_2413
Organism: Homo sapiens (Human)
Disease: Lung squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2413 Copy
https://web.expasy.org/cellosaurus/CVCL_1146
Organism: Homo sapiens (Human)
Disease: Lung small cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1146 Copy
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