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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_W168
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Comments: Miscellaneous: Cell line name and sex of donor from author direct submission.
Proper citation: RRID:CVCL_W168 Copy
https://web.expasy.org/cellosaurus/CVCL_B4IC
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Comments: Characteristics: Can be maintained in culture at the permissive temperature of 33 Celsius for up to 27 passages without signs of senescence.
Proper citation: RRID:CVCL_B4IC Copy
https://web.expasy.org/cellosaurus/CVCL_W186
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Proper citation: Ximbio Cat# 152135, RRID:CVCL_W186 Copy
https://web.expasy.org/cellosaurus/CVCL_YJ30
Organism: Sus scrofa (Pig)
Category: Conditionally immortalized cell line
Comments: Characteristics: Transduced with a P-TR3G-SV40largeT-T2A-mCherry-PhPGKp-PuroR-T2A-rTer-VP16 construct. The expression of the SV40 largeT antigen is under the control of the Tet-On system and induced by doxycycline.
Proper citation: RRID:CVCL_YJ30 Copy
https://web.expasy.org/cellosaurus/CVCL_6483
Organism: Oryctolagus cuniculus (Rabbit)
Category: Conditionally immortalized cell line
Comments: Characteristics: Bicarbonate-secreting., Characteristics: May be used to study terminal differentiation of intercalated cells (ATCC=CRL-2531).
Proper citation: RRID:CVCL_6483 Copy
https://web.expasy.org/cellosaurus/CVCL_B396
Organism: Mus musculus (Mouse)
Category: Conditionally immortalized cell line
Proper citation: RRID:CVCL_B396 Copy
https://web.expasy.org/cellosaurus/CVCL_F277
Organism: Mus musculus (Mouse)
Category: Conditionally immortalized cell line
Comments: Characteristics: Proliferates at permissive temperature (33 Celsius) in the presence of IFNG, terminally differentiates at restrictive temperature (39 Celsius) in the absence of IFNG.
Proper citation: RRID:CVCL_F277 Copy
https://web.expasy.org/cellosaurus/CVCL_B6F9
Organism: Rattus norvegicus (Rat)
Category: Conditionally immortalized cell line
Comments: Characteristics: Proliferates at the permissive temperature (33 Celsius). Rapid decrease in cell proliferation at the restrictive temperature (39 Celsius) (PubMed=10762059).
Proper citation: RRID:CVCL_B6F9 Copy
https://web.expasy.org/cellosaurus/CVCL_5737
Category: Conditionally immortalized cell line
Comments: Breed/subspecies: (CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse., Derived from sampling site: Kidney. Cell type=Podocyte., Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [tsA58].
Proper citation: RRID:CVCL_5737 Copy
https://web.expasy.org/cellosaurus/CVCL_A1TU
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Comments: Virology: Contains an integrated xenotropic MuLV-related virus (XMRV) Bxv-1 (from parent cell line EndoC-betaH2)., Characteristics: In this cell line the Fucci probe was produced by transducing two different constructs: LTR-mKO2/CDT1-IRES-PuroR-LTR and LTR-mAG/GMNN-IRES-ZeoR-LTR., Characteristics: Transduced with the Fucci probe which consist of the fusion of monomeric Kusabira-Orange2 (mKO2) to the ubiquitination domain of human CDT1 (AA 30-120) and monomeric AzamiGreen (mAG) to the ubiquitination domain of human geminin (AA 1-110)., Characteristics: The lentiviral vector insert containing the SV40 LT and hTERT can be excised by the Cre recombinase upon addition of tamixofen. Following excision of immortalizing transgenes, cell proliferation sharply decreases and in parallel there is a massive enhancement of beta cell-specific features such as increased INS gene expression.
Proper citation: RRID:CVCL_A1TU Copy
https://web.expasy.org/cellosaurus/CVCL_IS71
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Comments: Virology: Contains an integrated xenotropic MuLV-related virus (XMRV) Bxv-1 (PubMed=26901817)., Characteristics: The lentiviral vector insert containing the SV40 LT and hTERT can be excised by the Cre recombinase. Following excision of immortalizing transgenes, cell proliferation sharply decreases and in parallel there is a massive enhancement of beta cell-specific features such as increased INS gene expression.
Proper citation: RRID:CVCL_IS71 Copy
https://web.expasy.org/cellosaurus/CVCL_F700
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Comments: Characteristics: At the non-permissive temperature (37 Celsius) the cells stop growing and die after 7 days (PubMed=22672995).
Proper citation: RRID:CVCL_F700 Copy
https://web.expasy.org/cellosaurus/CVCL_WK94
Organism: Rattus norvegicus (Rat)
Category: Conditionally immortalized cell line
Comments: Characteristics: At the permissive temperature (33 Celsius) these cells are small and compact and divide. At the non-permissive temperature (40 Celsius) the cells assume a monolayer appearance and become differentiated (PubMed=9528980)., Characteristics: Responds to stimulation by PRL, estradiol and cAMP, making the cells a useful model for studies involving gene expression and regulation of luteal cells (ABM=T0596).
Proper citation: RRID:CVCL_WK94 Copy
https://web.expasy.org/cellosaurus/CVCL_IY27
Organism: Mus musculus (Mouse)
Category: Conditionally immortalized cell line
Proper citation: RRID:CVCL_IY27 Copy
https://web.expasy.org/cellosaurus/CVCL_IY26
Organism: Mus musculus (Mouse)
Category: Conditionally immortalized cell line
Proper citation: RRID:CVCL_IY26 Copy
https://web.expasy.org/cellosaurus/CVCL_A7FW
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Comments: Characteristics: In the presence of doxycycline, hTERT and SV40-TAg expression are activated, resulting in high cell proliferation and unlimited expansion. In the absence of the doxycycline, cells stop proliferating and can be maintained in a growth-arrested state that reflects the status of endothelial cells in vivo (PubMed=26345505)., Characteristics: Transduced with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
Proper citation: RRID:CVCL_A7FW Copy
https://web.expasy.org/cellosaurus/CVCL_D531
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Comments: Characteristics: Reversible immortalized. The cell line was obtained by transduction of a retrovirus containing SV40 LT flanked by a pair of LoxP recombination targets. The SV40 LT gene can be excised by Cre/Lox site-specific recombination., Population: Chinese.
Proper citation: RRID:CVCL_D531 Copy
https://web.expasy.org/cellosaurus/CVCL_3708
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Comments: Anecdotal: Have been flown in space on shuttle flight STS-80 to study growth in microgravity (PubMed=10719274)., Group: Space-flown cell line (cellonaut)., Group: Patented cell line.
Proper citation: RRID:CVCL_3708 Copy
https://web.expasy.org/cellosaurus/CVCL_4U69
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Proper citation: RRID:CVCL_4U69 Copy
https://web.expasy.org/cellosaurus/CVCL_J982
Organism: Homo sapiens (Human)
Category: Conditionally immortalized cell line
Comments: Donor information: Established from reduction mammoplasty tissue (PubMed=8206680).
Proper citation: RRID:CVCL_J982 Copy
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