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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Contaminated
https://web.expasy.org/cellosaurus/CVCL_2260
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=566722; PubMed=20143388). Originally thought to originate from the conjunctiva of a child..
Proper citation: RRID:CVCL_2260 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_2260
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=566722; PubMed=20143388). Originally thought to originate from the conjunctiva of a child..
Proper citation: KCLB Cat# 10020.2, RRID:CVCL_2260 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_2260
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=566722; PubMed=20143388). Originally thought to originate from the conjunctiva of a child..
Proper citation: ECACC Cat# 88021103, RRID:CVCL_2260 Copy
https://web.expasy.org/cellosaurus/CVCL_1H05
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: HIV-1 Rev and Env proteins are induced by removing tetracycline from the culture medium., Population: African American.
Proper citation: BEI_Resources Cat# ARP-3336, RRID:CVCL_1H05 Copy
https://web.expasy.org/cellosaurus/CVCL_1H06
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Group: Retrovirus packaging cell line.
Proper citation: BEI_Resources Cat# ARP-3337, RRID:CVCL_1H06 Copy
https://web.expasy.org/cellosaurus/CVCL_1E18
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American.
Proper citation: BEI_Resources Cat# ARP-11798, RRID:CVCL_1E18 Copy
https://web.expasy.org/cellosaurus/CVCL_B478
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American.
Proper citation: BEI_Resources Cat# ARP-8129, RRID:CVCL_B478 Copy
https://web.expasy.org/cellosaurus/CVCL_D8ER
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Parent cell line (BEL-7402) has been shown to be a HeLa derivative..
Proper citation: RRID:CVCL_D8ER Copy
https://web.expasy.org/cellosaurus/CVCL_U339
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American.
Proper citation: BEI_Resources Cat# ARP-1109, RRID:CVCL_U339 Copy
https://web.expasy.org/cellosaurus/CVCL_B0A4
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Facilitates the functional analysis of IFITMs and as well as their mechanisms of regulation. Can also be used to identify other innate immunity factors and/or screen for new anti-infective drug candidates (ATCC=CRL-3452)., Population: African American.
Proper citation: ATCC Cat# CRL-3452, RRID:CVCL_B0A4 Copy
https://web.expasy.org/cellosaurus/CVCL_B3LV
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Virology: Can be used to isolate human coronavirus NL63 (HCoV-NL63) (JCRB=JCRB1835)., Population: African American.
Proper citation: JCRB Cat# JCRB1835, RRID:CVCL_B3LV Copy
https://web.expasy.org/cellosaurus/CVCL_1D64
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American.
Proper citation: CLS Cat# 300674, RRID:CVCL_1D64 Copy
https://web.expasy.org/cellosaurus/CVCL_1D63
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American.
Proper citation: CLS Cat# 300673, RRID:CVCL_1D63 Copy
https://web.expasy.org/cellosaurus/CVCL_1D61
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American.
Proper citation: CLS Cat# 300668, RRID:CVCL_1D61 Copy
https://web.expasy.org/cellosaurus/CVCL_1D65
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American.
Proper citation: CLS Cat# 300920, RRID:CVCL_1D65 Copy
https://web.expasy.org/cellosaurus/CVCL_D259
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Virology: Can be used to determine quantitatively the titer of laboratory-adapted HIV-1 strains (PubMed=1548759)., Characteristics: Transfected with a construct pJK2 containing the HIV-1 LTR fused to a lacZ reporter gene that contains a MPKKKRK N-terminal sequence directing it to the nucleus (PubMed=1548759)., Population: African American.
Proper citation: BEI_Resources Cat# ARP-1470, RRID:CVCL_D259 Copy
https://web.expasy.org/cellosaurus/CVCL_E2QI
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American.
Proper citation: RRID:CVCL_E2QI Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0030
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: HeLa is the most frequent contributor to cell lines contamination., Anecdotal: Was flown since the 1960s on at least ten different space missions: Korabl-Sputnik-2, Vostok-1, Vostok-4, Vostok-5 and Vostok-6, Voshkod 1 and Zond-5, Discoverer XVIII, Progress M-35/Mir and Shuttle STS-89., Anecdotal: The HeLa cell line and its story inspired Australian artist Cynthia Verspaget to embark in 2003 on a artistic project 'The Anarchy Cell Line' (TAnCL) where she mixed her blood with HeLa cells. This work later spawned a PhD thesis (CelloPub=CLPUB00376) where among other things she makes the observation that two main taxonomical distinctions present in the zombie, living/dead and human/nonhuman, are also present in the HeLa cell line., Anecdotal: The fascinating story of the HeLa cell line and of Henrietta Lacks from whom these cells originate are described in the book of Rebecca Skloot (CelloPub=CLPUB00377)., Anecdotal: The HeLa cell line which was established in February 1951 is the oldest human immortal cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: HeLa has 5 five HPV18 integration sites: three on normal chromosomes 8 at 8q24 and two on derivative chromosomes, der(5)t(5;22;8)(q11;q11q13;q24) and der(22)t(8;22) (q24;q13)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Space-flown cell line (cellonaut).
Proper citation: Ubigene Cat# YC-A012, RRID:CVCL_0030 Copy
https://web.expasy.org/cellosaurus/CVCL_B3LW
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American.
Proper citation: JCRB Cat# JCRB1845, RRID:CVCL_B3LW Copy
https://web.expasy.org/cellosaurus/CVCL_UP51
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Stably expresses EGFP-LC3-mRFP-LC3delta, an autophagic flux probe. GFP-LC3 is fused to the N-terminus of RFP-LC3 whose C-terminal glycine is deleted. When expressed, the probe it is separated into EGFP-LC3 and mRFP-LC3deltaG by the action of endogenous ATG4 family proteases that cleave the peptide bond after the C-terminal glycine of LC3 in the cytosol producing equimolar amounts of EGFP-LC3 and mRFP-LC3deltaG., Population: African American.
Proper citation: RCB Cat# RCB4695, RRID:CVCL_UP51 Copy
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