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https://web.expasy.org/cellosaurus/CVCL_0303

Organism: Mus musculus (Mouse)
Category: Transformed cell line
Comments: Caution: The STR profile of HL-1 as distributed from Ubigene shows that the cell line that what they distribute is not HL-1 but C2C12 (Cellosaurus=CVCL_0188) or a derivative of that cell line (Ubigene=YC-C100)., Characteristics: From transgenic mice expressing a fusion gene comprised of the atrial natriuretic factor promoter and the SV40 early region., Characteristics: Spontaneously contract while maintaining a differentiated cardiac phenotype (Millipore=SCC065)., Group: Patented cell line.

Proper citation: RRID:CVCL_0303 Copy   

•   Source: Cellosaurus

https://web.expasy.org/cellosaurus/CVCL_8800

Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma activated B-cell type
Category: Cancer cell line
Comments: Caution: A cell line, now termed GNE-587170 (Cellosaurus=CVCL_AT69), was mistakenly distributed by OCI to a number of groups under the designation OCI-Ly-3, the origin of that cell line is now known., Population: Caucasian., From: Ontario Cancer Institute (OCI); Toronto; Canada., Part of: MD Anderson Cell Lines Project., Part of: LL-100 blood cancer cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Proper citation: RRID:CVCL_8800 Copy   

•   Source: Cellosaurus

https://web.expasy.org/cellosaurus/CVCL_0303

Organism: Mus musculus (Mouse)
Category: Transformed cell line
Comments: Caution: The STR profile of HL-1 as distributed from Ubigene shows that the cell line that what they distribute is not HL-1 but C2C12 (Cellosaurus=CVCL_0188) or a derivative of that cell line (Ubigene=YC-C100)., Characteristics: From transgenic mice expressing a fusion gene comprised of the atrial natriuretic factor promoter and the SV40 early region., Characteristics: Spontaneously contract while maintaining a differentiated cardiac phenotype (Millipore=SCC065)., Group: Patented cell line.

Proper citation: Millipore Cat# SCC065, RRID:CVCL_0303 Copy   

•   Source: Cellosaurus

https://web.expasy.org/cellosaurus/CVCL_0303

Organism: Mus musculus (Mouse)
Category: Transformed cell line
Comments: Caution: The STR profile of HL-1 as distributed from Ubigene shows that the cell line that what they distribute is not HL-1 but C2C12 (Cellosaurus=CVCL_0188) or a derivative of that cell line (Ubigene=YC-C100)., Characteristics: From transgenic mice expressing a fusion gene comprised of the atrial natriuretic factor promoter and the SV40 early region., Characteristics: Spontaneously contract while maintaining a differentiated cardiac phenotype (Millipore=SCC065)., Group: Patented cell line.

Proper citation: Ubigene Cat# YC-C100, RRID:CVCL_0303 Copy   

•   Source: Cellosaurus

https://web.expasy.org/cellosaurus/CVCL_RU08

Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Caution: Could be identical to 293T R-Spondin1 expressing (Cellosaurus=CVCL_RU09) distributed by Millipore. Both cell line product pages cite PubMed=19398967 but the Millipore page states "Cell line is not the published cell line from the Kuo lab, but rather a related cell line developed in the same lab using the reference protocol"., Characteristics: Expresses mouse Fc-Rspo1 which consist of the fusion of mouse IgG2a Fc region to the N-terminal of Rspo1 with a N-terminal HA epitope tag (AMSBIO).

Proper citation: RRID:CVCL_RU08 Copy   

•   Source: Cellosaurus

Possibly Discontinued Possibly Discontinued Possibly Discontinued

https://web.expasy.org/cellosaurus/CVCL_0040

Organism: Homo sapiens (Human)
Disease: Melanoma
Category: Cancer cell line
Comments: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: CSF1PO., Population: Caucasian., Part of: Wistar Institute melanoma cell line collection., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Proper citation: RRID:CVCL_0040 Copy   

•   Source: Cellosaurus

https://web.expasy.org/cellosaurus/CVCL_RU09

Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Caution: Could be identical to HA-R-Spondin1-Fc 293T (Cellosaurus=CVCL_RU08) distributed by AMSBIO. Both cell line product pages cite PubMed=19398967 but the Millipore page states "Cell line is not the published cell line from the Kuo lab, but rather a related cell line developed in the same lab using the reference protocol"., Characteristics: Expresses mouse Fc-Rspo1 which consist of the fusion of mouse IgG2a Fc region to the N-terminal of Rspo1 with a N-terminal HA epitope tag (Millipore=SCC111).

Proper citation: Millipore Cat# SCC111, RRID:CVCL_RU09 Copy   

•   Source: Cellosaurus

Possibly Discontinued Discontinued

https://web.expasy.org/cellosaurus/CVCL_6357

Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Comments: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: CSF1PO., Characteristics: Metastatic. Established from the lung of a nude mouse after 4 sequential passages of the parent cell line (PubMed=2156614)., Population: Caucasian., Part of: Wistar Institute melanoma cell line collection., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Proper citation: RRID:CVCL_6357 Copy   

•   Source: Cellosaurus

https://web.expasy.org/cellosaurus/CVCL_RU09

Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Caution: Could be identical to HA-R-Spondin1-Fc 293T (Cellosaurus=CVCL_RU08) distributed by AMSBIO. Both cell line product pages cite PubMed=19398967 but the Millipore page states "Cell line is not the published cell line from the Kuo lab, but rather a related cell line developed in the same lab using the reference protocol"., Characteristics: Expresses mouse Fc-Rspo1 which consist of the fusion of mouse IgG2a Fc region to the N-terminal of Rspo1 with a N-terminal HA epitope tag (Millipore=SCC111).

Proper citation: RRID:CVCL_RU09 Copy   

•   Source: Cellosaurus

Misidentified Discontinued

https://web.expasy.org/cellosaurus/CVCL_0022

Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 3., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Misidentified. This cell line is not the original glioblastoma cell line established in 1968 at the University of Uppsala. As described in PubMed=27582061 it is most probably also a glioblastoma cell line but whose origin is unknow. See U-87MG Uppsala (Cellosaurus=CVCL_GP63) for the original U-87MG cell line..

Proper citation: RRID:CVCL_0022 Copy   

•   Source: Cellosaurus

Partially Contaminated Possibly Discontinued Discontinued

https://web.expasy.org/cellosaurus/CVCL_5239

Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Comments: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: Amelogenin., Characteristics: Established from serial passaging of the parent cell line through immune deficient mice and harvesting lung metastasis., Population: Caucasian., Part of: Wistar Institute melanoma cell line collection., Problematic cell line: Partially contaminated. The stock formerly distributed by Coriell (WC00058) contains a significant amount of mouse DNA (DOI=10.4172/1948-5956.1000196). This is not the case of the original Wistar stock which was distributed by Rockland (DOI=10.4172/1948-5956.1000401)..

Proper citation: RRID:CVCL_5239 Copy   

•   Source: Cellosaurus

https://web.expasy.org/cellosaurus/CVCL_6571

Organism: Homo sapiens (Human)
Disease: Invasive breast carcinoma of no special type
Category: Cancer cell line
Comments: Characteristics: Acts through the activation of a luciferase reporter gene under the control of estrogen response elements (EREs) upstream of the mouse mammary tumor viral (MMTV) promoter., Characteristics: Emits measurable light in response to estrogen and estrogen-like substances. Used for identifying estrogen receptor agonists and antagonists., Biotechnology: Used in the Organisation for Economic Co-operation and Development (OECD) detection of estrogenic/antiestrogenic chemicals test method 457 (DOI=10.1787/9789264185395-en)., Biotechnology: Cell line developed for VM7Luc ER TA (VM7Luc Estrogen Receptor TransActivation) bioassay which was formerly known as BG1Luc ER TA (BG1Luc Estrogen Receptor TransActivation)., Population: Caucasian., Problematic cell line: Contaminated. Shown to be a MCF-7 derivative (EURL ECVAM-TSAR=TM2016-09). Originally thought to be a BG1 (Cellosaurus=CVCL_6570) derivative..

Proper citation: RRID:CVCL_6571 Copy   

•   Source: Cellosaurus

Discontinued

https://web.expasy.org/cellosaurus/CVCL_9720

Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Miscellaneous: This cell line is exclusively produced and controlled by Biopredic International and owned by Inserm. BioPredic sells undifferentiated cell line (HPR101) that can be expanded, passaged, and frozen in-house to prepare a cell bank and differentiated ready-to-use cells, HPR116 (Cellosaurus=CVCL_WL73) that can be used immediately or in a few days after thawing, as a single-use disposable product (Biopredic)., Anecdotal: The 'RG' in the cell name stands for 'Rumin' and 'Gripon', the two scientists that were influential in the establishment of this cell line., Characteristics: Cell line main applications are sugar and lipid metabolism, physiopathology; drug metabolism and toxicology and viral infection., Characteristics: Can be induced to differentiate into hepatocyte-like cells by exposure to DMSO., Group: Patented cell line.

Proper citation: Millipore Cat# C103485, RRID:CVCL_9720 Copy   

•   Source: Cellosaurus

Discontinued

https://web.expasy.org/cellosaurus/CVCL_9720

Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Miscellaneous: This cell line is exclusively produced and controlled by Biopredic International and owned by Inserm. BioPredic sells undifferentiated cell line (HPR101) that can be expanded, passaged, and frozen in-house to prepare a cell bank and differentiated ready-to-use cells, HPR116 (Cellosaurus=CVCL_WL73) that can be used immediately or in a few days after thawing, as a single-use disposable product (Biopredic)., Anecdotal: The 'RG' in the cell name stands for 'Rumin' and 'Gripon', the two scientists that were influential in the establishment of this cell line., Characteristics: Cell line main applications are sugar and lipid metabolism, physiopathology; drug metabolism and toxicology and viral infection., Characteristics: Can be induced to differentiate into hepatocyte-like cells by exposure to DMSO., Group: Patented cell line.

Proper citation: RRID:CVCL_9720 Copy   

•   Source: Cellosaurus

https://web.expasy.org/cellosaurus/CVCL_E8AV

Organism: Homo sapiens (Human)
Disease: Childhood T acute lymphoblastic leukemia
Category: Cancer cell line
Comments: Virology: Susceptible to infection by CXCR4-tropic HIV-1 strains (example HXB2) (PubMed=17182760)., Virology: Infected with Moloney murine leukemia virus (MoMuLV) from MiCl1 (S+L-) (Cellosaurus=CVCL_3405) cells (from parent cell line HPB-Ma)., Characteristics: Transfected with two constructs. 1) 53LTRN-lucneoR#1 which contains the HIV-1 strain HXB2 LTR driving the expression of a Luc-DsRed fusion protein. This allows HIV-1 replication to be quantitatively evaluated by using luciferase activity when the LTR is activated by Tat, and the DsRed gene allows HIV-1 infected cells to be identified by red fluorescence. 2) pRenillaPac where Renilla luciferase is under the control of a CMV promoter and is used to monitor cell numbers and viability (PubMed=17182760)., Characteristics: Reporter cell line to measure HIV-1 infectivity and thus evaluate susceptibility to anti-HIV-1 drugs (PubMed=17182760)., Population: Japanese.

Proper citation: RRID:CVCL_E8AV Copy   

•   Source: Cellosaurus

https://web.expasy.org/cellosaurus/CVCL_E8AW

Organism: Homo sapiens (Human)
Disease: Childhood T acute lymphoblastic leukemia
Category: Cancer cell line
Comments: Virology: Susceptible to infection by both CCR5-tropic (example JRCSF) and CXCR4-tropic HIV-1 strains (PubMed=17182760)., Virology: Infected with Moloney murine leukemia virus (MoMuLV) from MiCl1 (S+L-) (Cellosaurus=CVCL_3405) cells (from parent cell line X4-MaRBLE)., Characteristics: Transfected with three constructs. 1) 53LTRN-lucneoR#1 which contains the HIV-1 strain HXB2 LTR driving the expression of a Luc-DsRed fusion protein. This allows HIV-1 replication to be quantitatively evaluated by using luciferase activity when the LTR is activated by Tat, and the DsRed gene allows HIV-1 infected cells to be identified by red fluorescence. 2) pRenillaPac where Renilla luciferase is under the control of a CMV promoter and is used to monitor cell numbers and viability, 3) pCCR5/CEP4 which contains CCR5 under the control of a CMV promoter (PubMed=17182760)., Characteristics: Reporter cell line to measure HIV-1 infectivity and thus evaluate susceptibility to anti-HIV-1 drugs (PubMed=17182760)., Population: Japanese.

Proper citation: RRID:CVCL_E8AW Copy   

•   Source: Cellosaurus

Discontinued

https://web.expasy.org/cellosaurus/CVCL_0059

Organism: Chlorocebus sabaeus (Green monkey)
Category: Spontaneously immortalized cell line
Comments: Anecdotal: Verda reno means green kidney in Esperanto and Vero means truth also in Esperanto., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19). But Vero C1008 (often known as Vero E6) (Cellosaurus=CVCL_0574) seems to be more appropriate for amplification and quantification (PubMed=32511316; PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Biotechnology: Used for the production of the Sinovax SARS-CoV-2 (COVID-19) vaccine (Trade name: CoronaVac; also known as PiCoVacc) (DrugBank=DB15806). The cell line is used to produces the inactivated SARS-CoV-2 virus strain CN02 (PubMed=32376603)., Biotechnology: Used for the production of the Bharat Biotech SARS-CoV-2 (COVID-19) vaccine (Trade name: Covaxin; also known as BBV152) (DrugBank=DB15847). The cell line is used to produces a inactivated SARS-CoV-2 virus strain., Biotechnology: Used for the production of the tetravalent dengue vaccine (Trade Name: Dengvaxia)., Biotechnology: Used for the production of the live smallpox (vaccinia) vaccine (Trade name: ACAM2000)., Biotechnology: Used for the production of the live oral rotavirus vaccine (Trade Name: Rotarix)., Biotechnology: Used for the production of the Chromatographically Purified Rabies Vaccine (CPRV)., Biotechnology: Used for the production of the Purified Vero-cell Rabies Vaccine (PVRV) (Trade name: VERORAB)., Biotechnology: Used for the production of the inactivated poliovirus vaccine (Trade name: Imovax Polio)., Biotechnology: Used for the production of the Japanese encephalitis virus (JEV) vaccine (Trade name: IXIARO/JESPECT)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Non-human primate cell line.

Proper citation: RCB Cat# RCB0001, RRID:CVCL_0059 Copy   

•   Source: Cellosaurus

Discontinued

https://web.expasy.org/cellosaurus/CVCL_0059

Organism: Chlorocebus sabaeus (Green monkey)
Category: Spontaneously immortalized cell line
Comments: Anecdotal: Verda reno means green kidney in Esperanto and Vero means truth also in Esperanto., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19). But Vero C1008 (often known as Vero E6) (Cellosaurus=CVCL_0574) seems to be more appropriate for amplification and quantification (PubMed=32511316; PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Biotechnology: Used for the production of the Sinovax SARS-CoV-2 (COVID-19) vaccine (Trade name: CoronaVac; also known as PiCoVacc) (DrugBank=DB15806). The cell line is used to produces the inactivated SARS-CoV-2 virus strain CN02 (PubMed=32376603)., Biotechnology: Used for the production of the Bharat Biotech SARS-CoV-2 (COVID-19) vaccine (Trade name: Covaxin; also known as BBV152) (DrugBank=DB15847). The cell line is used to produces a inactivated SARS-CoV-2 virus strain., Biotechnology: Used for the production of the tetravalent dengue vaccine (Trade Name: Dengvaxia)., Biotechnology: Used for the production of the live smallpox (vaccinia) vaccine (Trade name: ACAM2000)., Biotechnology: Used for the production of the live oral rotavirus vaccine (Trade Name: Rotarix)., Biotechnology: Used for the production of the Chromatographically Purified Rabies Vaccine (CPRV)., Biotechnology: Used for the production of the Purified Vero-cell Rabies Vaccine (PVRV) (Trade name: VERORAB)., Biotechnology: Used for the production of the inactivated poliovirus vaccine (Trade name: Imovax Polio)., Biotechnology: Used for the production of the Japanese encephalitis virus (JEV) vaccine (Trade name: IXIARO/JESPECT)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Non-human primate cell line.

Proper citation: AddexBio Cat# P0014002/4920, RRID:CVCL_0059 Copy   

•   Source: Cellosaurus

Discontinued

https://web.expasy.org/cellosaurus/CVCL_0059

Organism: Chlorocebus sabaeus (Green monkey)
Category: Spontaneously immortalized cell line
Comments: Anecdotal: Verda reno means green kidney in Esperanto and Vero means truth also in Esperanto., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19). But Vero C1008 (often known as Vero E6) (Cellosaurus=CVCL_0574) seems to be more appropriate for amplification and quantification (PubMed=32511316; PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Biotechnology: Used for the production of the Sinovax SARS-CoV-2 (COVID-19) vaccine (Trade name: CoronaVac; also known as PiCoVacc) (DrugBank=DB15806). The cell line is used to produces the inactivated SARS-CoV-2 virus strain CN02 (PubMed=32376603)., Biotechnology: Used for the production of the Bharat Biotech SARS-CoV-2 (COVID-19) vaccine (Trade name: Covaxin; also known as BBV152) (DrugBank=DB15847). The cell line is used to produces a inactivated SARS-CoV-2 virus strain., Biotechnology: Used for the production of the tetravalent dengue vaccine (Trade Name: Dengvaxia)., Biotechnology: Used for the production of the live smallpox (vaccinia) vaccine (Trade name: ACAM2000)., Biotechnology: Used for the production of the live oral rotavirus vaccine (Trade Name: Rotarix)., Biotechnology: Used for the production of the Chromatographically Purified Rabies Vaccine (CPRV)., Biotechnology: Used for the production of the Purified Vero-cell Rabies Vaccine (PVRV) (Trade name: VERORAB)., Biotechnology: Used for the production of the inactivated poliovirus vaccine (Trade name: Imovax Polio)., Biotechnology: Used for the production of the Japanese encephalitis virus (JEV) vaccine (Trade name: IXIARO/JESPECT)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Non-human primate cell line.

Proper citation: JCRB Cat# IFO50471, RRID:CVCL_0059 Copy   

•   Source: Cellosaurus

Discontinued

https://web.expasy.org/cellosaurus/CVCL_0059

Organism: Chlorocebus sabaeus (Green monkey)
Category: Spontaneously immortalized cell line
Comments: Anecdotal: Verda reno means green kidney in Esperanto and Vero means truth also in Esperanto., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19). But Vero C1008 (often known as Vero E6) (Cellosaurus=CVCL_0574) seems to be more appropriate for amplification and quantification (PubMed=32511316; PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Biotechnology: Used for the production of the Sinovax SARS-CoV-2 (COVID-19) vaccine (Trade name: CoronaVac; also known as PiCoVacc) (DrugBank=DB15806). The cell line is used to produces the inactivated SARS-CoV-2 virus strain CN02 (PubMed=32376603)., Biotechnology: Used for the production of the Bharat Biotech SARS-CoV-2 (COVID-19) vaccine (Trade name: Covaxin; also known as BBV152) (DrugBank=DB15847). The cell line is used to produces a inactivated SARS-CoV-2 virus strain., Biotechnology: Used for the production of the tetravalent dengue vaccine (Trade Name: Dengvaxia)., Biotechnology: Used for the production of the live smallpox (vaccinia) vaccine (Trade name: ACAM2000)., Biotechnology: Used for the production of the live oral rotavirus vaccine (Trade Name: Rotarix)., Biotechnology: Used for the production of the Chromatographically Purified Rabies Vaccine (CPRV)., Biotechnology: Used for the production of the Purified Vero-cell Rabies Vaccine (PVRV) (Trade name: VERORAB)., Biotechnology: Used for the production of the inactivated poliovirus vaccine (Trade name: Imovax Polio)., Biotechnology: Used for the production of the Japanese encephalitis virus (JEV) vaccine (Trade name: IXIARO/JESPECT)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Non-human primate cell line.

Proper citation: ECACC Cat# 84113001, RRID:CVCL_0059 Copy   

•   Source: Cellosaurus