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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_8747
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Contaminated. Shown to be a KM12 derivative (PubMed=25714623). Originally thought to originate from a Japanese 51 year old female patient suffering from a peritoneal disseminated moderately differentiated adenocarcinoma of the cecum..
Proper citation: RRID:CVCL_8747 Copy
https://web.expasy.org/cellosaurus/CVCL_3786
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: Expresses a high level of GADD45A in an antisense orientation. Blocks de novo synthesis of GADD45A in response to DNA damage (PubMed=7973727).
Proper citation: RRID:CVCL_3786 Copy
https://web.expasy.org/cellosaurus/CVCL_AU13
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Proper citation: RRID:CVCL_AU13 Copy
https://web.expasy.org/cellosaurus/CVCL_AU14
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Proper citation: RRID:CVCL_AU14 Copy
https://web.expasy.org/cellosaurus/CVCL_HE23
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Proper citation: RRID:CVCL_HE23 Copy
https://web.expasy.org/cellosaurus/CVCL_LD07
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: Heterozygous knockin of a EGFR activating mutation.
Proper citation: RRID:CVCL_LD07 Copy
https://web.expasy.org/cellosaurus/CVCL_LE01
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: Heterozygous knockin of a EGFR activating mutation.
Proper citation: RRID:CVCL_LE01 Copy
https://web.expasy.org/cellosaurus/CVCL_HE19
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: RKO carries a stable triplication of the FANCC gene.
Proper citation: RRID:CVCL_HE19 Copy
https://web.expasy.org/cellosaurus/CVCL_LD10
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: Heterozygous knockin of a EGFR mutation conferring drug resistance.
Proper citation: RRID:CVCL_LD10 Copy
https://web.expasy.org/cellosaurus/CVCL_AU15
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Proper citation: RRID:CVCL_AU15 Copy
https://web.expasy.org/cellosaurus/CVCL_HE20
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: RKO carries a stable triplication of the FANCC gene.
Proper citation: RRID:CVCL_HE20 Copy
https://web.expasy.org/cellosaurus/CVCL_HE16
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: RKO carries a stable triplication of the BRAF gene with one wild-type (V-600) and two mutant alleles (E-600). This KO cell line carries both the wild-type and mutant alleles.
Proper citation: RRID:CVCL_HE16 Copy
https://web.expasy.org/cellosaurus/CVCL_HE21
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Proper citation: RRID:CVCL_HE21 Copy
https://web.expasy.org/cellosaurus/CVCL_LD09
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: Heterozygous knockin of a EGFR mutation.
Proper citation: RRID:CVCL_LD09 Copy
https://web.expasy.org/cellosaurus/CVCL_HE17
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: RKO carries a stable triplication of the BRAF gene with one wild-type (V-600) and two mutant alleles (E-600). This KO cell line carries only the mutant allele.
Proper citation: RRID:CVCL_HE17 Copy
https://web.expasy.org/cellosaurus/CVCL_D5XY
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_D5XY Copy
https://web.expasy.org/cellosaurus/CVCL_D6BA
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_D6BA Copy
https://web.expasy.org/cellosaurus/CVCL_E0W2
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: Transfected with two plasmids, XLone-GemininT25D and pCMV-hyPBase. The XLone-GemininT25D plasmid contains in one orientation a EF1A-rtTA-P2A-Bsd region where rtTA is a reverse tetracycline-controlled transactivator, a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16 and in the other orientation a TRE3G-GemininT25D region thus allowing the doxycycline induction of gemimin (DOI=10.1101/2024.02.02.578516)., Population: Caucasian.
Proper citation: RRID:CVCL_E0W2 Copy
https://web.expasy.org/cellosaurus/CVCL_E0W0
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Characteristics: Using CRISPR/Cas9 the fluorescent protein mClover was integrated at the C-terminus of MTBP (from parent cell line HCT-116 MTBP-mClover)., Characteristics: Transfected with two plasmids, XLone-GemininT25D and pCMV-hyPBase. The XLone-GemininT25D plasmid contains in one orientation a EF1A-rtTA-P2A-Bsd region where rtTA is a reverse tetracycline-controlled transactivator, a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16 and in the other orientation a TRE3G-GemininT25D region thus allowing the doxycycline induction of gemimin (DOI=10.1101/2024.02.02.578516)., Population: Caucasian.
Proper citation: RRID:CVCL_E0W0 Copy
https://web.expasy.org/cellosaurus/CVCL_E1K4
Organism: Homo sapiens (Human)
Disease: Colon carcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_E1K4 Copy
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