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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_A7ZS
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Stably expresses two reporter genes: SEAP (secreted ALPP) and the Lucia luciferase. In this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 NF-kappaB binding sites. The Lucia luciferase reporter gene is under the control of an ISG54 minimal promoter in conjunction with 5 IFN-stimulated response elements (ISRE) (InvivoGen=a549d-korigi-cov2r)., Characteristics: Ideal for studying SARS-CoV-2 viral entry into host cells, the viral RNA sensing pathway, as well as screening small molecule inhibitors and neutralizing antibodies. These cells are permissive to infection by SARS-CoV-2 Spike-pseudotyped viral particles (InvivoGen=a549d-korigi-cov2r)., Population: Caucasian., Group: SARS-CoV-2 research cell line.
Proper citation: RRID:CVCL_A7ZS Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_J242
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_J242 Copy
https://web.expasy.org/cellosaurus/CVCL_QZ79
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Reporter cell line, transduced with the LV-Fluc-P2A-Puro vector encoding for luciferase linked via a P2A cleavage peptide to the PuroR gene and under control of the spleen focus-forming virus (SFFV) promoter (Imanis=CL080)., Population: Caucasian.
Proper citation: RRID:CVCL_QZ79 Copy
https://web.expasy.org/cellosaurus/CVCL_A9MC
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Transduced with a Cas9-FLAG-Neo construct., Population: Caucasian.
Proper citation: RRID:CVCL_A9MC Copy
https://web.expasy.org/cellosaurus/CVCL_QZ83
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Reporter cell line, transduced with both the LV-hNIS-IRES-Neo and LV-iRFP-P2A-Puro vectors. LV-hNIS-IRES-Neo encodes for human SLC5A5 linked via an internal ribosomal entry site (IRES) to the Neo gene and under control of the spleen focus-forming virus (SFFV) promoter. LV-iRFP-P2A-Puro encodes for iRFP linked via a P2A cleavage peptide to the PuroR gene and under control of the spleen focus-forming virus (SFFV) promoter (Imanis=CL084)., Population: Caucasian.
Proper citation: RRID:CVCL_QZ83 Copy
https://web.expasy.org/cellosaurus/CVCL_QZ76
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Reporter cell line, transduced with the LV-eGFP-PGKp-Puro vector encoding for eGFP under control of the spleen focus-forming virus (SFFV) promoter and the PuroR gene under the control of the mouse PGK promoter (Imanis=CL079)., Population: Caucasian.
Proper citation: RRID:CVCL_QZ76 Copy
https://web.expasy.org/cellosaurus/CVCL_A7ZR
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Stably expresses two reporter genes: SEAP (secreted ALPP) and the Lucia luciferase. In this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 NF-kappaB binding sites. The Lucia luciferase reporter gene is under the control of an ISG54 minimal promoter in conjunction with 5 IFN-stimulated response elements (ISRE) (InvivoGen=a549d-komda5-cov2r)., Characteristics: Ideal for studying SARS-CoV-2 viral entry into host cells, the viral RNA sensing pathway, as well as screening small molecule inhibitors and neutralizing antibodies. These cells are permissive to infection by SARS-CoV-2 Spike-pseudotyped viral particles (InvivoGen=a549d-komda5-cov2r)., Population: Caucasian., Group: SARS-CoV-2 research cell line.
Proper citation: RRID:CVCL_A7ZR Copy
https://web.expasy.org/cellosaurus/CVCL_A5KA
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Permissive to infection by SARS-CoV-2 and/or spike-pseudotyped lentiviral particles (InvivoGen=a549-hace2)., Population: Caucasian., Group: SARS-CoV-2 research cell line.
Proper citation: RRID:CVCL_A5KA Copy
https://web.expasy.org/cellosaurus/CVCL_A7ZN
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Stably expresses two reporter genes: SEAP (secreted ALPP) and the Lucia luciferase. In this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 NF-kappaB binding sites. The Lucia luciferase reporter gene is under the control of an ISG54 minimal promoter in conjunction with 5 IFN-stimulated response elements (ISRE) (InvivoGen=a549d-korigi)., Population: Caucasian.
Proper citation: RRID:CVCL_A7ZN Copy
https://web.expasy.org/cellosaurus/CVCL_4Z15
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_4Z15 Copy
https://web.expasy.org/cellosaurus/CVCL_IY87
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_IY87 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_KS36
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Discontinued: Thermo Fisher/Panomics; Catalog number RC0002., Characteristics: The luciferase reporter gene is under the control of multiple copies of the NF-kappaB response element (PubMed=16834536)., Population: Caucasian.
Proper citation: RRID:CVCL_KS36 Copy
https://web.expasy.org/cellosaurus/CVCL_XE67
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_XE67 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_5J13
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_5J13 Copy
https://web.expasy.org/cellosaurus/CVCL_VR73
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Using CRISPR/Cas9 a construct containing KRAB-dCas9-2A-Pac-2A-RFP-PA was introduced in the AAVS1 safe harbor locus., Population: Caucasian.
Proper citation: RRID:CVCL_VR73 Copy
https://web.expasy.org/cellosaurus/CVCL_XY99
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Transfected with the ScFV sequence of anti-human CD3 mAb OKT3 and a C-terminal domain of mouse CD8a which consists of the transmembrane and cytoplasmic domains., Population: Caucasian.
Proper citation: RRID:CVCL_XY99 Copy
https://web.expasy.org/cellosaurus/CVCL_A0WA
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Transduced with both a CBG-T2A-GFP construct and a NY-ESO-1-T2A-HLA-A2 construct., Population: Caucasian.
Proper citation: RRID:CVCL_A0WA Copy
https://web.expasy.org/cellosaurus/CVCL_RX09
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Expression of eGFP is under the control of the control of the mouse Mx2 promoter (PubMed=27346232)., Biotechnology: Used for a reporter gene assay (RGA) of the human type 1 interferon potency (PubMed=27346232)., Population: Caucasian.
Proper citation: RRID:CVCL_RX09 Copy
https://web.expasy.org/cellosaurus/CVCL_QZ77
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Reporter cell line, transduced with both the LV-Fluc-P2A-Neo and LV-eGFP-PGKp-Puro vectors. LV-Fluc-P2A-Neo encodes for luciferase linked via a P2A cleavage peptide to the neo gene and under control of the spleen focus-forming virus (SFFV) promoter. LV-eGFP-PGKp-Puro encodes for eGFP under control of the spleen focus-forming virus (SFFV) promoter and the PuroR gene under the control of the mouse PGK promoter (Imanis=CL097)., Population: Caucasian.
Proper citation: RRID:CVCL_QZ77 Copy
https://web.expasy.org/cellosaurus/CVCL_XB27
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_XB27 Copy
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