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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_EP43
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: Donor information: Established from monozygotic twin of UCSD201i-4-2 (Cellosaurus=CVCL_EP44)., Population: Southeast Asian; Filipino., From: Frazer, Kelly A.; University of California, San Diego; San Diego; USA., Part of: Next Generation Genetic Association studies (Next Gen) program cell lines., Part of: iPSC Collection for Omic Research (iPSCORE).
Proper citation: WiCell Cat# ucsd200i-4-1, RRID:CVCL_EP43 Copy
https://web.expasy.org/cellosaurus/CVCL_EP44
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: Donor information: Established from monozygotic twin of UCSD200i-4-1 (Cellosaurus=CVCL_EP43)., Population: Southeast Asian; Filipino., From: Frazer, Kelly A.; University of California, San Diego; San Diego; USA., Part of: Next Generation Genetic Association studies (Next Gen) program cell lines., Part of: iPSC Collection for Omic Research (iPSCORE).
Proper citation: WiCell Cat# ucsd201i-4-2, RRID:CVCL_EP44 Copy
https://web.expasy.org/cellosaurus/CVCL_EP44
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: Donor information: Established from monozygotic twin of UCSD200i-4-1 (Cellosaurus=CVCL_EP43)., Population: Southeast Asian; Filipino., From: Frazer, Kelly A.; University of California, San Diego; San Diego; USA., Part of: Next Generation Genetic Association studies (Next Gen) program cell lines., Part of: iPSC Collection for Omic Research (iPSCORE).
Proper citation: RRID:CVCL_EP44 Copy
https://web.expasy.org/cellosaurus/CVCL_F0FY
Organism: Homo sapiens (Human)
Disease: Ehlers-Danlos syndrome, type IV
Category: Finite cell line
Comments: Caution: The cell line is indicated by PubMed=2722184 to originate from the same patient as Lu-Rob (Cellosaurus=CVCL_3010) but no name is given, just the initials "L.R". We have thus named it Lu Rob 2 as we could not find any ATCC document indicating its name.
Proper citation: RRID:CVCL_F0FY Copy
https://web.expasy.org/cellosaurus/CVCL_1559
Organism: Homo sapiens (Human)
Disease: Minimally invasive lung adenocarcinoma
Category: Cancer cell line
Comments: Caution: NCI-H358 and NCI-H358M (Cellosaurus=CVCL_JA53) could be identical., Population: Caucasian., Part of: NCI RAS program mutant KRAS cell line panel., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1559 Copy
https://web.expasy.org/cellosaurus/CVCL_EP43
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: Donor information: Established from monozygotic twin of UCSD201i-4-2 (Cellosaurus=CVCL_EP44)., Population: Southeast Asian; Filipino., From: Frazer, Kelly A.; University of California, San Diego; San Diego; USA., Part of: Next Generation Genetic Association studies (Next Gen) program cell lines., Part of: iPSC Collection for Omic Research (iPSCORE).
Proper citation: RRID:CVCL_EP43 Copy
Possibly Misidentified/Contaminated
https://web.expasy.org/cellosaurus/CVCL_4057
Organism: Homo sapiens (Human)
Disease: Pancreatic adenocarcinoma
Category: Cancer cell line
Comments: From: Scott and White Clinic; Temple; USA., Problematic cell line: Possibly misidentified/contaminated. Reported by PubMed=11787853 to contain the same HPV18 sequences as the cervix carcinoma cell line C-4-I (Cellosaurus=CVCL_2253) and to lack mutations in KRAS, TP53, CDKN2 and DPC4 often found in pancreatic adenocarcinoma..
Proper citation: RRID:CVCL_4057 Copy
https://web.expasy.org/cellosaurus/CVCL_F0FY
Organism: Homo sapiens (Human)
Disease: Ehlers-Danlos syndrome, type IV
Category: Finite cell line
Comments: Caution: The cell line is indicated by PubMed=2722184 to originate from the same patient as Lu-Rob (Cellosaurus=CVCL_3010) but no name is given, just the initials "L.R". We have thus named it Lu Rob 2 as we could not find any ATCC document indicating its name.
Proper citation: RRID:CVCL_F0FY Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_6789
Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Comments: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: CSF1PO., Part of: Wistar Institute melanoma cell line collection., Part of: MD Anderson Cell Lines Project.
Proper citation: RRID:CVCL_6789 Copy
https://web.expasy.org/cellosaurus/CVCL_WR44
Organism: Homo sapiens (Human)
Disease: Adult acute myeloid leukemia with maturation
Category: Cancer cell line
Comments: Caution: Not to be confused with HL60/AR (Cellosaurus=CVCL_WI27) which is an 5-azacytidine resistant subline of HL-60., Anecdotal: Have been flown in space on shuttle flight STS-67 to study the effect of microgravity on multidrug resistance (PubMed=9434637)., Population: Caucasian., Group: Space-flown cell line (cellonaut).
Proper citation: RRID:CVCL_WR44 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_6799
Organism: Homo sapiens (Human)
Disease: Melanoma
Category: Cancer cell line
Comments: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: Amelogenin., Part of: Wistar Institute melanoma cell line collection., Part of: MD Anderson Cell Lines Project.
Proper citation: RRID:CVCL_6799 Copy
https://web.expasy.org/cellosaurus/CVCL_A0SA
Organism: Mus musculus (Mouse)
Category: Hybridoma
Comments: Caution: The myeloma fusion partner is indicated to be Sp2/0-Ag14 in Patent=US5710255 and to be FO (Cellosaurus=CVCL_6972) in PubMed=7510760. While this hybridoma is not described by the patent, 6 other hybridomas are described in both sources thus this one was probably produced in an identical manner.
Proper citation: RRID:CVCL_A0SA Copy
Misclassified Discontinued
https://web.expasy.org/cellosaurus/CVCL_2991
Organism: Homo sapiens (Human)
Category: Undefined cell line type
Comments: Population: Japanese., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Misclassified. Originally thought to be a myeloma cell line and to be a sister line to KMS-21-PE (Cellosaurus=CVCL_A445) but this does not seem to be the case (PubMed=12592342; PubMed=20143388)..
Proper citation: RRID:CVCL_2991 Copy
Misidentified Discontinued
https://web.expasy.org/cellosaurus/CVCL_4363
Organism: Homo sapiens (Human)
Disease: Lung small cell carcinoma
Category: Cancer cell line
Comments: Problematic cell line: Misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (PubMed=20143388). Furthermore its STR profile is different from that of the cell line NCI-BL1514 (Cellosaurus=CVCL_2641) which is supposed to originate from the same individual, a 56 year old Caucasian woman..
Proper citation: RRID:CVCL_4363 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_4380
Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma
Category: Cancer cell line
Comments: Caution: Was reported in Cellosaurus and the ICLAC Register (from 2018 to early 2022) to be a SU-DHL-8 contaminated cell line but there seem to have been an issue with the sample tested. DSMZ has obtained original stock from Epstein A.L. and SU-DHL-7 is a genuine non-problematic cell line.
Proper citation: DSMZ Cat# ACC-903, RRID:CVCL_4380 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_4380
Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma
Category: Cancer cell line
Comments: Caution: Was reported in Cellosaurus and the ICLAC Register (from 2018 to early 2022) to be a SU-DHL-8 contaminated cell line but there seem to have been an issue with the sample tested. DSMZ has obtained original stock from Epstein A.L. and SU-DHL-7 is a genuine non-problematic cell line.
Proper citation: RRID:CVCL_4380 Copy
https://web.expasy.org/cellosaurus/CVCL_G365
Organism: Homo sapiens (Human)
Disease: Clear cell renal cell carcinoma
Category: Cancer cell line
Comments: Caution: The age/sex of donor of this cell line and that of SKR1 (Cellosaurus=CVCL_G366), both described in PubMed=9183637 are inverted in the abstract of that paper. We believe that the information in the material and methods section is the correct one as it is corroborated by the karyotype information in the same paper., Population: Japanese.
Proper citation: RRID:CVCL_G365 Copy
https://web.expasy.org/cellosaurus/CVCL_A341
Organism: Homo sapiens (Human)
Disease: Melanoma
Category: Cancer cell line
Comments: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: Amelogenin., Population: Caucasian., Part of: Wistar Institute melanoma cell line collection., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_A341 Copy
https://web.expasy.org/cellosaurus/CVCL_GP63
Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Comments: Caution: This is the original U-87MG cell line established in 1968 at the University of Uppsala. The cell line distributed by most cell collections (including ATCC, CLS, ECACC, etc.) is a different cell line whose origin is not yet clear (PubMed=27582061). See U-87MG ATCC (Cellosaurus=CVCL_0022) for the cell line used by most research groups.
Proper citation: RRID:CVCL_GP63 Copy
https://web.expasy.org/cellosaurus/CVCL_D6MH
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: Caution: There is a major issue with this cell line. It is indicated to be derived from ATCC-DYR0100 (Cellosaurus=CVCL_C253), a male cell line, but the karyotype of this cell line is female and the paper also indicates that it originate from a Chinese female newborn., Population: Chinese., From: Sun Yat-sen University First Affiliated Hospital; Guangzhou; China.
Proper citation: RRID:CVCL_D6MH Copy
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