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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_B6ER
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Characteristics: Transduced with three constructs: 1) a retroviral vector SSR#197 (MoMLV/LTR-LoxP-hTERT-IRES-EGFP-LoxP-MoMLV/LTR) expressing hTERT and eGFP flanked by a pair of loxP sites, 2) a plasmid pCAGMerCreMer/Puro that expresses Cre fused to 2 mutant estrogen-receptor ligand-binding domains (MerCreMer) under the control of the CAG promoter and 3) a plasmid vector expressing modified insulin and zeocin resistance genes under the control of the rat L-PK promoter., Characteristics: Reversibly immortalized; exposure to tamoxifen induces the expression of the Cre gene that effects Cre/LoxP recombination and excise the TERT gene., Characteristics: Expresses an insulin variant which is a single-chain modified insulin which is made of the signal sequence of albumin, the A chain followed by short turn-forming heptapeptide (GGGPGKR) and the B chain. This construct does not require pancreas-specific enzymatic processing (PubMed=14693704).
Proper citation: RRID:CVCL_B6ER Copy
https://web.expasy.org/cellosaurus/CVCL_VL06
Organism: Homo sapiens (Human)
Disease: Nijmegen breakage syndrome
Category: Telomerase immortalized cell line
Proper citation: RRID:CVCL_VL06 Copy
https://web.expasy.org/cellosaurus/CVCL_N806
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Senescence: Cells can be senesced after exposure for 72 hours with 4-hydroxy-tamoxifen., Characteristics: Transduced with a construct that is composed of EGFP at the N-terminus, the catalytic domain of RAF1 (with p.Tyr340Asp and p.Tyr341Asp) in the middle and the hormone-binding domain of ESR1 at the C-terminus. Protein kinase activity is activated by estrogen or analogs such as 4-hydroxy-tamoxifen., Population: Caucasian; Swedish., Part of: ENCODE project common cell types; tier 3.
Proper citation: RRID:CVCL_N806 Copy
https://web.expasy.org/cellosaurus/CVCL_B5SZ
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Miscellaneous: STR profile and sex of donor from personal communication of Evercyte.
Proper citation: RRID:CVCL_B5SZ Copy
https://web.expasy.org/cellosaurus/CVCL_ZS67
Organism: Homo sapiens (Human)
Disease: Xeroderma pigmentosum variant type
Category: Telomerase immortalized cell line
Comments: Population: Iranian.
Proper citation: RRID:CVCL_ZS67 Copy
https://web.expasy.org/cellosaurus/CVCL_B7IB
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_B7IB Copy
https://web.expasy.org/cellosaurus/CVCL_B7I4
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_B7I4 Copy
https://web.expasy.org/cellosaurus/CVCL_Z586
Organism: Sus scrofa (Pig)
Category: Telomerase immortalized cell line
Proper citation: RRID:CVCL_Z586 Copy
https://web.expasy.org/cellosaurus/CVCL_L238
Organism: Homo sapiens (Human)
Disease: Oral epithelial dysplasia
Category: Telomerase immortalized cell line
Proper citation: RRID:CVCL_L238 Copy
https://web.expasy.org/cellosaurus/CVCL_A9G0
Organism: Homo sapiens (Human)
Disease: Werner syndrome
Category: Telomerase immortalized cell line
Comments: Characteristics: Transduced with a lentiviral vector containing a LTR-loxP-hTERT-SV40p-hisD-PuroR-LTR construct., Population: Caucasian.
Proper citation: RRID:CVCL_A9G0 Copy
https://web.expasy.org/cellosaurus/CVCL_3092
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_3092 Copy
https://web.expasy.org/cellosaurus/CVCL_3107
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_3107 Copy
https://web.expasy.org/cellosaurus/CVCL_3096
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_3096 Copy
https://web.expasy.org/cellosaurus/CVCL_3102
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_3102 Copy
https://web.expasy.org/cellosaurus/CVCL_3106
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_3106 Copy
https://web.expasy.org/cellosaurus/CVCL_3099
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_3099 Copy
https://web.expasy.org/cellosaurus/CVCL_3094
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_3094 Copy
https://web.expasy.org/cellosaurus/CVCL_3098
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_3098 Copy
https://web.expasy.org/cellosaurus/CVCL_3100
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_3100 Copy
https://web.expasy.org/cellosaurus/CVCL_3093
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_3093 Copy
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