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Protocol Name
Genotyping the ADAMTS5-P (Pfizer) mouse strain
DOI:10.17504/protocols.io.kaucsew RRID Copied  
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Bianca Hemmeryckx, Dries Bauters, H. Roger Lijnen 2018. Genotyping the ADAMTS5-P (Pfizer) mouse strain. protocols.io dx.doi.org/10.17504/protocols.io.kaucsew
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Protocol Information

URL: https://dx.doi.org/10.17504/protocols.io.kaucsew

Authors: Bianca Hemmeryckx, Dries Bauters, H. Roger Lijnen

Summary: ADAMTS5, the main aggrecanase, is a protein that seems to play a functional role in the development of brown and white adipose tissue (WAT) and browning of WAT. These published observations were made using the ADAMTS5-P mice originally generated by Pfizer, in collaboration with Lexicon Genetics (The Woodlands, TX, USA).

Associated Publications: Bauters D, Bedossa P, Lijnen HR, Hemmeryckx B (2018) Functional role of ADAMTS5 in adiposity and metabolic health. PLoS ONE 13(1): e0190595. doi: 10.1371/journal.pone.0190595

Affiliations: KU Leuven, KU Leuven, KU Leuven

External URL: https://doi.org/10.1371/journal.pone.0190595

Version: 1

Publication Date: 2018

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Source: Protocols.io