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URL: https://dx.doi.org/10.17504/protocols.io.bka6kshe

Authors: Hasheemah Afaneh , Gabrielle Gonzalez, Olivia Sugarman, Edward Trapido, Susanne Straif-Bourgeois, Evrim Oral, Ashley Wennerstrom

Group: Louisiana State University Health Sciences Center - New Orleans

Summary: As of 2017, there were more than three million individuals in the United States infected with Hepatitis C virus (HCV) [1]. Because most cases are asymptomatic, leading to a higher rate of unreported cases, this number is suspected to be much higher. Furthermore, there is a rise of HCV cases, and this increase documented since 2013 is primarily due to injection drug transmission alongside the rise of the opioid epidemic [2]. The Centers for Disease Control and Prevention (CDC) encourages HCV testing for all adults at least once in their lifetime, and those that test positive for HCV should be linked to treatment [3]. In 2013, only 13%-18% of patients with HCV received treatment in that year, indicating that there are barriers to treatment, such as lack of treatment acceptance, co-existing conditions, extensive treatment, side-effects, and access to treatment[4]. Thus, health disparities may ensue and the eradication of HCV as a public health issue becomes even more challenging. Edlin and Winkelstein (2014) suggested that to achieve optimal HCV eradication, social determinants of health, such as homelessness, need to be addressed [5]. Because there is room for improvement in linkage-to-care opportunities, it is important to explore whether linkage-to-care interventions address social determinants of health, and if so, which ones, to obtain a better understanding of what may help improve patient outcomes.References: U.S. Department of Health and Human Services. 2019.Retrieved June 11, 2020, fromhttps://www.hhs.gov/opa/reproductive-health/fact-sheets/sexually-transmitted-diseases/hepatitis-c/index.htmlCentersfor Disease Control and Prevention(CDC). 2019. Commentary portion of U.S. 2017 Surveillance Data for Viral Hepatitis. Retrieved June 11, 2020, fromhttps://www.cdc.gov/hepatitis/statistics/2017surveillance/index.htmSchillie, S., Wester, C., Osborne, M., Wesolowski, L., & Ryerson, A.B. (2020). CDC Recommendations for Hepatitis C Screening Among Adults – United States, 2020. MMWR Recommendations & Reports, 69(2), 1-17.https://www.cdc.gov/mmwr/volumes/69/rr/rr6902a1.htmInfectious Disease Society of America. 2019. HCV Testing and Linkage to Care: HCV Guidance. Retrieved June 23, 2020, fromhttps://www.hcvguidelines.org/evaluate/testing-and-linkageEdlin, B. & Winkelstein, E. (2014). “Can Hepatitis C be eradicated in the U.S.?”Antiviral Research.110: 79-93.https://dx.doi.org/10.1016/j.antiviral.2014.07.015

Affiliations: LSUHSC School of Public Health Office of Research in Public Health, LSUHSC School of Public Health Behavioral and Community Health Sciences , LSUHSC School of Public Health Behavioral and Community Health Sciences , LSUHSC School of Public Health Epidemiology, LSUHSC School of Public Health Epidemiology, LSUHSC School of Public Health Biostatistics, LSUHSC Center for Healthcare Value and Equity & School of Public Health Behavioral and Community Health

Version: 1

Publication Date: 2020

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