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Protocol Name
DOI:10.17504/protocols.io.bjy7kpzn RRID Copied  
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Angel  Justiz-Vaillant 2020. ELISA for quantification of IL-6 in human serum or plasma.. protocols.io dx.doi.org/10.17504/protocols.io.bjy7kpzn
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Protocol Information

URL: https://dx.doi.org/10.17504/protocols.io.bjy7kpzn

Authors: Angel Justiz-Vaillant

Group: University of the West Indies, [email protected]

Summary: Interleukin-10 is a pleiotropic cytokine playing a critical role as a regulator of myeloid and lymphoid cell function. Due to the ability of IL-10 to blocking cytokine synthesis and many accessory cell functions of antigen-presenting cells such as macrophages this cytokine is a potent suppressor of the effector functions of macrophages, T-cells and NK cells. IL-10 also participates in regulating proliferation and differentiation of B-lymphocytes, mast cells and thymocytes [1]. Reference1. Ouyang W, O'Garra A. IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation.Immunity. 2019;50(4):871-891. doi:10.1016/j.immuni.2019.03.020

Affiliations: University of the West Indies St. Augustine

Version: 1

Publication Date: 2020

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Source: Protocols.io