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Protocol Name
Levodopa kinetic-dynamic test
DOI:10.17504/protocols.io.bbq8imzw RRID Copied  
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Manuela Contin  2020. Levodopa kinetic-dynamic test. protocols.io dx.doi.org/10.17504/protocols.io.bbq8imzw
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Protocol Information

URL: https://dx.doi.org/10.17504/protocols.io.bbq8imzw

Authors: Manuela Contin

Summary: Levodopa oral test Administration of a subacutest dose of levodopa (100 mg) plus benserazide (25 mg) or carbidopa (25 mg) under standardized conditions.Levodopa kinetic–dynamic monitoringMeasurements of plasma levodopa concentrations and clinical effects by objective motor tests (alternate finger tapping test).

Associated Publications: Ursino M, Magosso E, Lopane G, Calandra-Buonaura G, Cortelli P, Contin M (2020) Mathematical modeling and parameter estimation of levodopa motor response in patients with parkinson disease. PLoS ONE 15(3): e0229729. doi: 10.1371/journal.pone.0229729

Affiliations: IRCCS- Istituto delle Scienze Neurologiche di Bologna- Dipartmento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna Italy

External URL: https://doi.org/10.1371/journal.pone.0229729

Version: 1

Publication Date: 2020

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Source: Protocols.io