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URL: https://dx.doi.org/10.17504/protocols.io.6pnhdme

Authors: Rona Ortenberg, Erez Nissim Baruch

Summary: This protocol allows to prepare paraffin block of any cell line or co-cultured cells and subsequently these blocks could be used for cell microarray construction. Slides are suitable for ICH/IF staining procedures.Cell microarray can be used, exactly like a tissue microarray, as a high-throughput tool for omics validation or investigation of functional dynamics of targets during a prolonged cell-cell interaction or any other treatments.

Associated Publications: Baruch EN, Ortenberg R, Avivi C, Anafi L, Dick-Necula D, Stossel C, Moshkovits Y, Itzhaki O, Besser MJ, Schachter J, Barshack I, Markel G, Immune co-culture cell microarray – a feasible tool for high-throughput functional investigation of lymphocyte–cancer interactions. Oncoimmunology 9(1). doi: 10.1080/2162402X.2020.1741267

Affiliations: The Ella Lemelbaum Institute for Immuno-Oncology, Sheba Medical Center, Tel-HaShomer, Israel, Department of Clinical Immunology and Microbiology, Sackler Faculty of Medicine, Tel Aviv University, Israel, The Ella Lemelbaum Institute for Immuno-Oncology, Sheba Medical Center, Tel-HaShomer, Israel

External URL: https://doi.org/10.1080/2162402X.2020.1741267

Version: 1

Publication Date: 2019

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