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URL: http://www.wormbase.org/db/get?name=WBStrain00062724
Proper Citation: RRID:WB-STRAIN:WBStrain00062724
Description: Caenorhabditis elegans with name haps-1(ljt1) I. from WB.
Species: Caenorhabditis elegans
Synonyms: haps-1(ljt1) I.
Notes: CRISPR-engineered KO strain of haps-1 made by knock-in of tandem stop codons to the first exon of endogenous haps-1 locus. haps-1(C48B6.3) is the C. elegans ortholog of human HAPSTR1. haps-1(ljt1) is superficially wild-type when cultured at 20C, but is hypersensitive to paraquat (redox stress), MLN4924 (neddylation inhibition), and camptothecin (genotoxic stress). Reference: Amici DR, et al. Proc Natl Acad Sci U S A. 2022 Jul 5;119(27):e2111262119. doi: 10.1073/pnas.2111262119. PMID: 35776542.
Affected Gene: WBGene00016741(haps-1)
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Source: Integrated Animals
Source Database: WormBase (WB)