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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=126777687
Proper Citation: RRID:RGD_126777687
Description: Rattus norvegicus with name WKY-Dnd1ter/Ztm from RGD.
Species: Rattus norvegicus
Notes: A spontaneous mutation (ter) leading to the formation of congenital ovarian and testicular tumors was detected in the WKY/Ztm rat strain. Sequence analysis detected a point mutation in exon 4 of the rat Dnd1, which introduces a premature stop codon assumed to cause a truncation of the Dnd1 protein. This recessive ter mutation has a complete penetrance of teratocarcinogenesis and infertility of both sexes in homozygous genotype.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
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