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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41882
Proper Citation: RRID:MMRRC_041882-UNC
Description: Mus musculus with name B6;SJL-Prop1df Tg(PROP1)884Sac/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology, Developmental Biology, Endocrine Deficiency, Models for Human Disease, Research Tools; Mutation Type: Transgenic ; Collection:
Phenotype: abnormal pituitary gland morphology [MP:0000633]| small ovary [MP:0001127]| absent corpus luteum [MP:0001134]| decreased body size [MP:0001265]| male infertility [MP:0001925]| female infertility [MP:0001926]| premature death [MP:0002083]| pituitary gland hypoplasia [MP:0002659]| absent ovarian follicles [MP:0002777]| decreased circulating follicle stimulating hormone level [MP:0002790]| small thyroid gland [MP:0002951]| abnormal pituitary gland development [MP:0003816]| decreased pituitary hormone level [MP:0003972]| decreased circulating thyroid-stimulating hormone level [MP:0005119]| decreased circulating growth hormone level [MP:0005120]| decreased circulating prolactin level [MP:0005121]| decreased follicle stimulating hormone level [MP:0005130]| decreased luteinizing hormone level [MP:0005132]| decreased thyroid-stimulating hormone level [MP:0005134]| decreased growth hormone level [MP:0005136]| abnormal enzyme/coenzyme activity [MP:0005584]| absent adenohypophysis [MP:0008320]| small adenohypophysis [MP:0008321]| absent somatotrophs [MP:0008330]| absent gonadotrophs [MP:0008336]| decreased thyrotroph cell number [MP:0008338]| proportional dwarf [MP:0008974]| small Rathke's pouch [MP:0013349]| abnormal Rathke's pouch development [MP:0013351]| abnormal Rathke's pouch apoptosis [MP:0013352]
Affected Gene: PROP1||Prop1|
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)