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Proper Citation: RRID:MGI:2446424
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased activated T cell number, abnormal T cell differentiation, enlarged spleen, spleen hyperplasia, abnormal T cell physiology, enlarged lymph nodes, decreased T cell proliferation, abnormal CD4-positive, alpha beta T cell morphology, increased IgG1 level, small thymus, increased IgE level, premature death, enlarged spleen, increased autoantibody level, enlarged lymph nodes, abnormal lymph organ size, increased anti-nuclear antigen antibody level, abnormal double-negative T cell morphology, abnormal CD8-positive, alpha beta T cell morphology, abnormal CD4-positive, alpha beta T cell morphology, decreased double-positive T cell number, abnormal cytokine secretion, decreased thymocyte number, abnormal immunoglobulin level, increased anti-double stranded DNA antibody level, increased T cell proliferation, increased IgM level
Affected Gene: Lat
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI