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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=407450413
Proper Citation: RRID:RGD_407450413
Description: Rattus norvegicus with name SD-Il6em1Yona-/- from RGD.
Species: Rattus norvegicus
Notes: The Il6 knockout (KO) rats were generated using the CRISPR/Cas9 technique to induce a shift in the reading frame of the second exon of Il6 by KAC Co. Ltd (Kyoto, Japan). This strain carried a 118 bp deleted in the second exon of IL-6 National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka 564-8565, Japan
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)