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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=38543943
Proper Citation: RRID:RGD_38543943
Description: Rattus norvegicus with name SD-Rag2em1Hera from RGD.
Species: Rattus norvegicus
Notes: The Rag2 gene in rat spermatogonia stem cells (SSC, SD-WT2) was targeted by TALENs and resulted in a 27-bp in-frame deletion. The genome modified SSC was transplanted to Busulfan-treated, Dazl-deficient male Sprague Dawley rats and mated with wild type female Sprague Dawley rats 70 to 81 later. The allele was then bred to homozygosity to generate the Sprague-Dawley Rag2 (SDR)-knockout rat.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
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