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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=149735570
Proper Citation: RRID:RGD_149735570
Description: Rattus norvegicus with name F344-Atg16l1em8Rrrc from RGD.
Species: Rattus norvegicus
Notes: CRISPR-Cas9-mediated knock-in of a single base pair polymorphism of guanine to alanine in exon 10, resulting in a threonine to alanine substitution at amino acid position 299 in the rat. Mimics the same nucleotide substitution for the threonine to alanine substitution at amino acid position 300 in humans (T300A), Homozygosity for this allele is embryonic lethal. RRRC
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
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