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URL: https://web.expasy.org/cellosaurus/CVCL_RJ11
Proper Citation: RRID:CVCL_RJ11
Description: Cell line HCT 116 CMV-OsTIR1 is a Cancer cell line with a species of origin Homo sapiens (Human)
Sex: Male
Disease: Colon carcinoma
Defining Citation: PMID:27052166
Comments: Characteristics: Using CRISPR/Cas9 a CMV-OsTIR1-PuroR (pMK232) vector was introduced in both alleles of the AAVS1 safe harbor locus., Characteristics: Parent cell line to study the rapid depletion of a protein. The expressed rice TIR1 can form a functional SCF(OsTIR1) E3 ligase complex with the endogenous components in human cells. In the presence of auxin, a protein of interest fused with mAID is rapidly degraded upon poly-ubiquitylation., Population: Caucasian.
Category: Cancer cell line
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Source: Cellosaurus
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