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URL: https://web.expasy.org/cellosaurus/CVCL_E7G0
Proper Citation: RRID:CVCL_E7G0
Description: Cell line CHO-SIINFEKL/H-2Kb is a Spontaneously immortalized cell line with a species of origin Cricetulus griseus (Chinese hamster)
Sex: Female
Defining Citation: PMID:30347189
Comments: Characteristics: Using a sleeping beauty transposon system a SIINFEKL-linker-B2m-linker-H2K(b)-AviTag construct was integrated in the parent cell line (PubMed=30347189)., Characteristics: Enables the large-scale and continuous batch production of soluble, fully folded and epitope-defined MHC class I molecules. Engineered to secrete peptide/MHC complexes that can be selectively purified in bulk using affinity chromatography, biotinylated, multimerized (via streptavidin) and the resulting reagent incorporated into immunologically relevant assays for detection of antigen-specific T-cells (PubMed=30347189).
Category: Spontaneously immortalized cell line
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Source: Cellosaurus
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