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URL: https://web.expasy.org/cellosaurus/CVCL_6861
Proper Citation: RRID:CVCL_6861
Description: Cell line Caov-2 is a Cancer cell line with a species of origin Homo sapiens (Human)
Sex: Female
Disease: Lung adenocarcinoma
Defining Citation: PMID:3518877, PMID:22710073
Comments: Caution: Was thought to be an OVCAR-2 derivative because its STR profile was identical to that originally reported for that cell line (PubMed=22710073). But this was shown (September 2025) not to be the correct STR profile for OVCAR-2. Meanwhile it was also noticed that the Caov-2 STR profile is identical to that of Calu-6., Population: Caucasian., Problematic cell line: Contaminated. On the basis of its STR profile it seems to be a Calu-6 derivative. Originally thought to originate from an ovarian carcinoma..
Category: Cancer cell line
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No rating or validation information has been found for Caov-2.
Contaminated
Problematic cell line: Contaminated. Shown to be a OVCAR-2 derivative (PubMed=22710073).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00458.
Discontinued
Discontinued: ATCC; HTB-74
Source: Cellosaurus (RRID:SCR_013869)
Description: Database of all cell lines used in biomedical research which include immortalized cell lines, naturally immortal cell lines (stem cells), widely used and distributed finite life cell lines, vertebrate cell lines (majority being human, mouse, and rat), and invertebrate (insects and ticks) cell lines, as well as cell line synonyms. Each cell line is provided with the following information: the recommended name (the name which appears in the original publication), a list of synonyms, a unique accession number, comments on a number of topics including misspellings and gene transfection, information on the tissue/organ origin with the UBERON code, the NCI Thesaurus or Orphanet ORDO code for the disease(s) the individual suffered from (for cancer and human genetic disease lines only), the species of origin, the parent cell line, cross-references of sister cell lines, the sex of the individual, the category in which the cell line belongs (Adult stem cell; Cancer cell line; Embryonic stem cell; Factor-dependent cell line; Finite cell line; Hybrid cell line; Hybridoma; Induced pluripotent stem cell; Spontaneously immortalized cell line; Stromal cell line; Telomerase immortalized cell line; Transformed cell line; Undefined cell line type), web links, publication references, and/or cross-references to cell line catalogs/collections, ontologies, cell lines databases/resources, and to databases that list cell lines as samples.
URL: https://www.cellosaurus.org/
dkNET can assist you in preparing authentication plans for cell lines to comply with the NIH Submission Policy. The information can be used while planning your experiments or submitting grant applications. The authentication plan for the cell lines is based on the International Cell Line Authentication Committee (ICLAC)'s "Cell Line Checklist for Manuscripts and Grant Applications" and the example "Authentication of of Key Biological and/or Chemical Resources "(Bandrowski A). For best practices for authenticating cell lines, check our Authentication Reports services.
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