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dkNET community events and announcements in March, 2019

dkNET community events and announcements in March, 2019

Dear dkNET Community,

dkNET provides updates on activities of interest to the NIDDK-supported community. You could keep up to date on these activities through our Twitter feed @dkNET_info, through our Community Calendar, or through dkNET e-mail list. If you have an event or funding opportunities you'd like to advertise, please contact us info_at_dknet.org.

dkNET News

  • dkNET 3.0 Beta has been released to the public in February, 2019! Our new features include: Resource Reports, Discovery Portal, Rigor & Reproducibility Support, Hypothesis Center. We would like you to take a look and let us know what your think! Check out our blog article about what's new and our help page to learn more about dkNET 3.0 Beta!

  • Will you attend ENDO2019 in New Orleans, LA? Come meet dkNET team on March 25, 2019 from 1PM to 3PM to learn about dkNET's new feature - Resource Reports! Dr. Ko-Wei Lin will have a poster presentation on "Making Informed Decisions on the Selection of Antibodies Using dkNET" at ENDOExpo Session P52 MON-176.

  • For those who will be attending Experimental Biology 2019 in Orlando, FL, don't forget to stop by dkNET booth #940 9:00am - 4:00pm ET from April 7-9, 2019! dkNET team will be there to give you a demo about what's new at dkNET 3.0's and answer your questions. We will also have a poster presentation "dkNET: Research tools that assist scientists in improving the rigor and reproducibility of their research" on April 9, 2019  at 11:45am- 12:45pm at Exhibit Hall-West Hall B (session program802.60; poster board A60). 

  • dkNET Summer of Data Student Internship - dkNET is launching the 6-week dkNET Summer of Data Student Internship program, to provide students an opportunity to utilize the dkNET tools and resources in a research project and to provide feedback on their experience to the dkNET team. dkNET will provide up to five (5) $5,000 awards to support a summer internship for either high school, undergraduate or graduate (Masters or PhD) students to support their research using the dkNET information portal. Application due date: April 5, 2019.

Events in March, 2019

Mar. 2, 2019 

2019 Michigan Diabetes Research Center Annual Symposium

SPEAKERS: Jean Schaffer, MD (Kroc Lecturer), Virginia Minnic h Distinguished Professor of Medicine; Director, Diabetes Research Center; Washington University School of Medicine; Jun Wu, PhD, Assistant Professor, Molecular and Integrative Physiology; Life Sciences Institute; University of Michigan; Marianna Sadagurski, PhD, Assistant Professor, Department of Biological Sciences, IBio; (Integrative Biosciences Center) Wayne State University; Roger D. Cone, PhD, Vice Provost and Director of the Biosciences Initiative; Mary Sue Coleman Director, Life Sciences Institute; Professor, Molecular and Integrative Physiology; University of Michigan.

Location: Ann Arbor, MI, USA

More information:  http://diabetesresearch.med.umich.edu/Calendar.php

Mar. 2-6, 2019

63TH Annual Meeting of the Biophysical Society

As science becomes increasingly interdisciplinary, the Biophys ical Society Annual Meeting continues its long-held reputation for bringing together leading scientists from the all over the world who work at the in terface of the life, physical, and computational sciences. The dynamic five-day Meeting provides attendees with opportunities to share their latest unpublished findings and learn the newest emerging techniques and applications.

Location: Baltimore, MD, USA

More information:  https://www.biophysics.org/2019meeting/general-info

Mar. 3-7, 2019

Keystone Symposia - Diabetes: Innovations, Outcomes and Personaliz ed Therapies (X3)

Diabetes: Innovations, Outcomes and Personalized Therapies (X3 ) joint with the meeting on Unraveling the Secrets of Kidney Disease (X4) March 3-7, 2019 Whistler Conference Centre, Whistler, British Columbia, Canada Supported by the Directors' Fund Diabetes remains a public health challenge of epidemic proportions. Modern treatment algorithms are evolving to recommend higher focus on personalized approaches to diabetes care. However, as diabetes remains a disease characterized by excess elevation of a plasma biomarker, glucose, further refinement of our understanding of the disease and its comorbidities is required to provide optimal guidance for precision medicine. Advancement of research technologies and the ability to handle large data sets have enabled systems biology approaches to unravel different etiologies and pathophysiological consequences of diabetes. Future diabetes discovery efforts will focus on pairing knowledge about genetic risk and environmental triggers of diabetes associated pathologies. Using deep phenome characterization and molecular network analyses diabetes researchers will be able to launch modern translational approaches to diabetes care innovation. The objectives of the conference are to provide directional guidance for future pressure points of diabetes care and put emphasis on specific diabetes complications representing particular unmet needs. Further, forefront discoveries of genetic risk determinants and their molecular mechanisms will be presented together with lively debetes about the translatability of such insights to novel curative therapies.

More information:  http://keystonesymposia.org/index.cfm?e=web.meeting.program&meetingid=1631

Mar. 3, 2019

Keynote Symposia: Unraveling the Secrets of Kidney Disease

Close to 1 in 11 people in the world suffers from kidney disease. The incidence of kidney disease is increasing especially in the developing world. This issue was recently reviewed and emphasized in a Lancet article (Global Health Atlas). Acute and chronic kidney disease is associated with a highly significant increase in cardiovascular death. Chronic kidney disease (CKD) represents a leading cause of death in the United States. There is no cure for this disease, with current treatment strategies relying on blood pressure control through blockade of the renin-angiotensin system. Such approaches only delay the development of end-stage kidney disease and can be associated with serious side effects. Recent identification of several novel mechanisms contributing to CKD development - including vascular changes, loss of podocytes and renal epithelial cells, matrix deposition, inflammation and metabolic dysregulation - has revealed new potential therapeutic approaches for CKD. This meeting will review clinical and observational studies in the kidney disease area, highlight recent advances in basic biology of kidney and kidney disease, assesses emerging strategies and agents for CKD treatment, and discuss major obstacles in drug development. This meeting will also encourage collaborations among clinicians and researchers from academic institutes and pharmaceutical laboratories and accelerate innovation in this field. There has not been a meeting in the area in kidney disease that would bring together clinicians, basic scientists and industry and foster collaboration. Small focus meetings have been organized by the International Society of Nephrology, but these meetings are limited to a single special topic. Furthermore more than half of kidney disease is caused by diabetes, this meeting will have the opportunity to understand diabetes and its complications development.

Location: Whistler, BC V0N, Canada
More info rmation: https://calendar.google.com/calendar/b/1/r/eventedit?tab=mc http: //keystonesymposia.org/index.cfm?e=web.meeting.program&meetingid=1630

Mar. 5-8, 2019

ASBMB Deuel Conference

The Deuel Conference meets for two and one-half days annually at various West Coast locations and centers around an aspect of lipid metabolism. The Conference consists of five sessions and maintains an informal at mosphere, encourages free and open discussion, and is a forum for present ation of new and unpublished data. Attendees enjoy the informality and the Deuel conference provides the depth and breadth of expertise necessary for a high quality conference. Participation is by investigators in the field of lipids and lipoproteins from the around the world. Interested scientists are invited to register to attend the meeting and encourage trainees to submit abstracts.

Location: Dana Point, CA, USA
More inform ation: https://www.asbmb.org/deuelconference/

Mar.10, 2019

Gordon Research Conference: The Impact of IGF and Insulin on Life-Long Health

The 2019 Gordon Research Conference on the IGF and Insulin System in Physiology and Disease will showcase innovative, cutting-edge research on the fundamental roles of IGF and insulin in normal physiology and in diseases particularly related to aging, cancer and metabolic disorders. IGFs and insulin are conserved throughout evolution to mediate the effects of nutrition on growth, metabolism and development, and hence play a major role in health and disease over the lifespan. They modulate diverse aspects of cell function such as proliferation, differentiation, survival and metabolism of most physiological systems in the body. The IGF family of ligands, receptors and IGF binding proteins are frequently disturbed in many pathological conditions, such as growth failure, diabetes, cancer and dege nerative diseases, and therefore have become attractive therapeutic targets. This conference will encompass ground-breaking information regarding key characteristics of the biology of the IGF/insulin family in both normal physiology and in pathological states highlighting innovative methodologies and novel interactions (e.g. stem cell biology and the microbiome). The goal of this conference is to bring together scientists at every level from dif ferent disciplines to interact during programmed topic sessions and informal gatherings to discuss new and seminal findings with experts in the field. The GRC will also include a GRC Power Hour that will be open to all meeting participants and will address the challenges women face in science. The conference will be preceded by a two-day Gordon Research Seminar for scienti sts in training. All these opportunities will support professional growth of younger scientists that will promote future collaborations and enhance participation and contribution to this exciting field.

Location: Ventura, CA, USA

More information:  https://www.grc.org/igf-and-insulin-system-in-physiology-and-disease-conference/2019/

Mar. 23-26, 2019

*ENDO 2019 (Meet dkNET team on March 25, 2019 1pm- 3pm at ENDOEXpo session P52 MON-176!) 

ENDO 2019 is coming to the Ernest N. Morial Convention Center i n New Orleans, LA, from March 23-26, 2019. It promises to be an experience you can’t miss with an extensive program featuring cutting-edge science, poster sessions, Meet-the-Professor sessions, the newest products and technologies at ENDOExpo, and more.

Location: New Orleans, LA, USA

More information:  https://www.endocrine.org/endo2019

Mar. 29- Apr. 3, 2019

American Association for Cancer Research

The AACR Annual Meeting program covers the latest discoveries across the spectrum of cancer research—from population science and prevention; to cancer biology, translational, and clinical studies; to survivors hip and advocacy—and highlights the work of the best minds in research and medicine from institutions all over the world.

Location: Atlanta, GA, USA

More information:  https://www.aacr.org/Meetings/Pages/MeetingDetail.aspx?EventItemID=174&\;DetailItemID=832

Mar. 31- Apr. 4, 2019

Keystone Symposia: Lipidomics and Functional Metabolic Pathways in Disease (C6)

Location: Steamboat Springs, CO 80487, USA

More information:  https://www.keystonesymposia.org/index.cfm?e=web.Meeting.Program&\;meetingid=1595

Mar. 31- Apr. 4, 2019

MSACL 2019 US 11th Annual Conference & Exhibits

MSACL (The American for Mass Spectrometry: Applications to the Clinical Lab) provides a forum for discussing the clinical application of mass spectrometry by bringing together academic and industrial experts in the field with those driven to explore and understand more about the potential application and benefits. The mission of MSACL is to accelerate the imple mentation of mass spectrometry in the clinical laboratory with the goal of contributing to the improvement of patient standard-of-care as well as reducing health care costs.

Location: Palm Springs, CA, USA

More information:  https://www.msacl.org

Mar. 31, 2019

Application deadline: Gordon Research Conference: Multi-Drug Efflux Systems -Translating Multifaceted Molecular Mechanisms into Pharmacological Interventions for Advancing Global Health

This conference will include presentations on key developments across a broad spectrum of topics covering the multiple roles of efflux transporter pumps in health and disease. The impact of the explosion of structural data from cryo-EM on our molecular understanding of the substrate selectivity and regulation of the transport of molecules across cell membranes will be highlighted. Speakers will discuss the role of multidrug efflux pumps as barriers to harmful xenobiotics, including roles in protecting the CNS, the fetus and the reproductive organs. The program will also include talks on the interrelatedness between pharmacological targeting of efflux pumps and systemic toxicity and key strategies for CNS penetration for the treatment of neurodegeneration and other neurological disorders in the scope of aging-related diseases. A discussion of how microbial strategies for drug resistance can be harnessed for reversing the current crises in the treatment of malaria, multidrug extensively resistant tuberculosis and multidrug resistance in Gram positive and Gram negative bacteria is planned. How the antimicrobial war can be supported by a healthy microbiome and the importance of transport and signaling among biofilms will also be subject of intense debate. Overall, this conference will foster discussion at the frontiers of science in multi-drug efflux systems for advancing global health and the UN Sustainable Development Goals envisaging a world with equitable and universal access to quality education and health care, where physical, mental and social well-being are assured. This GRC will also be held in conjunction with the Gordon Research Seminar for young scientists (April 27-28).

Location: Lucca, 55100 Lucca, Province of Lucca, Italy

More information:  https://www.grc.org/multi-drug-efflux-systems-conference/2019/

Funding opportunities information and deadlines in March, 2019

Mar. 1, 2019 

Funding Opportunity Application Due Date: MMPC MICROMouse Program

The MMPC MICROMouse Program is a competitive grants program awa rding up to $75,000 (total costs) for one year to fund research projects that have the potential to enhance and advance the mission of the MMPC as a resource for scientists using mice to study diabetes and obesity. Any independent investigator, including post-doctoral fellows, is eligible to apply. A project must be either: 1) resource-development (e.g., develop, improve, miniaturize, teach, distribute, etc. phenotyping tests for use in mice); or 2) resource-related research (e.g., a new, currently unfunded project where results have potential impact for mouse centered research in diabetes or obesity, particularly those focused on broad biological questions that impact the ability of the MMPC to meet its goals). There is no for mal deadline associated with MICROMouse applications, but applications will be reviewed quarterly (March 1, June 1, September 1, December 1) and therefore should be submitted accordingly.

More information:  https://www.mmpc.org/shared/microMouse.aspx

Mar. 10, 2019 

NIDDK Funding Opportunity Letter of Intent due date: The KUH/NIDDK Predoctoral to Postdoctoral Fellow Transition Award (F99/K00 Independent Clinical Trial Not Allowed)

The purpose of the KUH/NIDDK Predoctoral to Postdoctoral Fellow Transition Award (F99/K00) is to recruit exceptional graduate students who are recognized by their institutions for their high potential and to incentivize them to pursue a Kidney, Urologic or Hematologic (K, U, or H) postdoctoral position that ultimately positions them to become independent K, U, or H researchers. This two-phase award will facilitate completion of t he doctoral dissertation and stabilize the transition of highly talented Ph.D candidates from a variety of fields, including, but not limited to, engineering, statistics, data science, imaging, biochemistry and genetics into strong postdoctoral appointments that are focused on K, U, or H re search. It is anticipated that successful completion of this phased award will make the individual highly competitive for a subsequent NIDDK award (e .g., K99/R00, R01). Opportunities for career development activities relevant to their long-term career goals of becoming independent researchers will be provided. Graduate students who are already involved in K, U, or H research are encouraged to apply for the NIDDK F31 (PA-18-671).

NIDDK Funding Opportunity Letter of Intent Due Date: Advanced Clinical Trials to test Artificial Pancreas Device Systems in Type 1 Diabetes (U01 Clinical Trial Required)

This FOA will support the conduct of advanced clinical trials designed to test the outpatient clinical safety and efficacy of artificial pancreas (AP) device systems in type 1 diabetes with the objective of improving glycemic control, reducing acute complications and improving quality of life. These trials should generate data able to satisfy safety and efficacy requirements by regulatory agencies regarding the clinical testing of AP device systems.

More information:  https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-18-025.html

Mar. 21, 2019 

NIDDK Funding Opportunity Letter of Intent Due Date: Development of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (R43/44 Clinical Trial Not Allowed) 

This Funding Opportunity Announcement (FOA) invites Small Busin ess Innovation Research (SBIR) grant applications for funding to perform re search leading to the development of novel and supportive technologies for the improvement of cell replacement interventions using novel methods, bio materials and devices for type 1 diabetes (T1D) treatment.

Mar.  24, 2019 

NIDDK Funding Opportunity Letter of Intent Due Date: Multidisciplinary Urologic Research (KURe) Career Development Program (K12 Clinical Trial Optional) 

The purpose of this Funding Opportunity Announcement (FOA) is to invite applications to support institutional career development programs in urological research that will assist MDs, PhDs, and MD/PhDs with an in terest in benign urological disease or urological research to develop the skills necessary to initiate and sustain an independent research career in urological research. Research areas supported by this initiative must be re lated to the mission of the NIDDK (http://www2.niddk.nih.gov/Research/ScientificAreas/Urology/). This Funding Opportunity Announcement (FOA) allows appointment of Scholars proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

More information:  https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-18-027.html


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