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URL: https://www.jax.org/strain/000664
Proper Citation: RRID:IMSR_JAX:000664
Description: Mus musculus with name C57BL/6J from IMSR.
Species: Mus musculus
Synonyms: B6. B6J. Black 6. C57 Black. C57BL/6JAnu
Notes: gene symbol note: gamma-aminobutyric acid type A receptor subunit alpha 2|forebrain weight 1|purinergic receptor P2X; ligand-gated ion channel; 7|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|nuclear encoded tRNA arginine 5 (anticodon TCT)|glucose homeostasis QTL 1|glucose homeostasis QTL 2|forebrain weight 2|MX dynamin-like GTPase 1|nicotinamide nucleotide transhydrogenase|arylalkylamine N-acetyltransferase|latent transforming growth factor beta binding protein 4|beta-2 microglobulin|NLR family; pyrin domain containing 12|CD5 antigen|microwave induced increase in complement receptor B cells|glucose homeostasis QTL 3|cadherin related 23 (otocadherin)|aryl-hydrocarbon receptor|annexin A6|hemoglobin beta chain complex|cytochrome c oxidase subunit 7A2 like; inbred strain: Gabra2|Fbrwt1|P2rx7|Apobec3|n-TRtct5|Gluchos1|Gluchos2|Fbrwt2|Mx1|Nnt|Aanat|Ltbp4|B2m|Nlrp12|Cd5|Micrl|Gluchos3|Cdh23|Ahr|Anxa6|Hbb|Cox7a2l
Affected Gene: gamma-aminobutyric acid type A receptor subunit alpha 2|forebrain weight 1|purinergic receptor P2X; ligand-gated ion channel; 7|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|nuclear encoded tRNA arginine 5 (anticodon TCT)|glucose homeostasis QTL 1|glucose homeostasis QTL 2|forebrain weight 2|MX dynamin-like GTPase 1|nicotinamide nucleotide transhydrogenase|arylalkylamine N-acetyltransferase|latent transforming growth factor beta binding protein 4|beta-2 microglobulin|NLR family; pyrin domain containing 12|CD5 antigen|microwave induced increase in complement receptor B cells|glucose homeostasis QTL 3|cadherin related 23 (otocadherin)|aryl-hydrocarbon receptor|annexin A6|hemoglobin beta chain complex|cytochrome c oxidase subunit 7A2 like
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Issue
Warning this mouse may be epileptogenic. The cause seems to be that the GABAA receptor is expressed at very low levels compared to other mouse strains including the C57BL/6N, according to Hawkins (2016) and Mulligan (2019).
Source: Integrated Animals
Source Database: JAX Mice and Services
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