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URL: https://www.jax.org/strain/000664
Proper Citation: RRID:IMSR_JAX:000664
Description: Mus musculus with name C57BL/6J from IMSR.
Species: Mus musculus
Synonyms: B6. B6J. Black 6. C57 Black. C57BL/6JAnu
Notes: gene symbol note: cytochrome c oxidase subunit 7A2 like|NLR family; pyrin domain containing 12|forebrain weight 2|MX dynamin-like GTPase 1|glucose homeostasis QTL 2|purinergic receptor P2X; ligand-gated ion channel; 7|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|cadherin related 23 (otocadherin)|glucose homeostasis QTL 1|microwave induced increase in complement receptor B cells|arylalkylamine N-acetyltransferase|gamma-aminobutyric acid type A receptor subunit alpha 2|hemoglobin beta chain complex|aryl-hydrocarbon receptor|nicotinamide nucleotide transhydrogenase|latent transforming growth factor beta binding protein 4|annexin A6|beta-2 microglobulin|CD5 antigen|nuclear encoded tRNA arginine 5 (anticodon TCT)|forebrain weight 1|glucose homeostasis QTL 3; inbred strain: Cox7a2l|Nlrp12|Fbrwt2|Mx1|Gluchos2|P2rx7|Apobec3|Cdh23|Gluchos1|Micrl|Aanat|Gabra2|Hbb|Ahr|Nnt|Ltbp4|Anxa6|B2m|Cd5|n-TRtct5|Fbrwt1|Gluchos3
Affected Gene: cytochrome c oxidase subunit 7A2 like|NLR family; pyrin domain containing 12|forebrain weight 2|MX dynamin-like GTPase 1|glucose homeostasis QTL 2|purinergic receptor P2X; ligand-gated ion channel; 7|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|cadherin related 23 (otocadherin)|glucose homeostasis QTL 1|microwave induced increase in complement receptor B cells|arylalkylamine N-acetyltransferase|gamma-aminobutyric acid type A receptor subunit alpha 2|hemoglobin beta chain complex|aryl-hydrocarbon receptor|nicotinamide nucleotide transhydrogenase|latent transforming growth factor beta binding protein 4|annexin A6|beta-2 microglobulin|CD5 antigen|nuclear encoded tRNA arginine 5 (anticodon TCT)|forebrain weight 1|glucose homeostasis QTL 3
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Issue
Warning this mouse may be epileptogenic. The cause seems to be that the GABAA receptor is expressed at very low levels compared to other mouse strains including the C57BL/6N, according to Hawkins (2016) and Mulligan (2019).
Source: International Mouse Strain Resource (RRID:SCR_001526)
Description: Database of mouse strains and stocks available worldwide, that will assist international research community in finding mouse resources they need, including inbred, mutant, and genetically engineered mice. IMSR is multi institutional international collaboration supporting use of mouse as model system for studying human biology and disease. IMSR began with initial collaboration between Mouse Genome Informatics (MGI) group at Jackson Laboratory and Medical Research Council Mammalian Genetics Unit at Harwell. Additional institutions and collaborators are now contributing mouse resource information to IMSR. Data content found in IMSR is as it was supplied by data provider sites. You are encouraged to participate in making this database as complete as possible for all worldwide mouse strain resources. If you or your institution hold mice, cryopreserved gametes or embryos, or ES cell lines that you distribute to other researchers, contributing information about them to IMSR catalog will make them more widely known.
URL: http://www.findmice.org/index.jsp
Source Database: JAX Mice and Services
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