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Norway

PMID:29045568  

Loss of Protein Kinase Novel 1 (PKN1) is associated with mild systolic and diastolic contractile dysfunction, increased phospholamban Thr17 phosphorylation, and exacerbated ischaemia-reperfusion injury.

Asvi A Francois | Kofo Obasanjo-Blackshire | James E Clark | Andrii Boguslavskyi | Mark R Holt | Peter J Parker | Michael S Marber | Richard J Heads
Cardiovascular research | 2018

PKN1 is a stress-responsive protein kinase acting downstream of small GTP-binding proteins of the Rho/Rac family. The aim was to determine its role in endogenous cardioprotection.

Pubmed ID: 29045568

Research resources used in this publication

None found

Antibodies used in this publication

None found

Associated grants

  • Agency: British Heart Foundation, United Kingdom
    Id: PG/10/045/28276

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