T1DR JAX Webinar on Modeling Diet-Induced Obesity in Mice on June 16, 2016

The Jackson Laboratory’s Type 1 Diabetes Resource (T1DR) Webinar: Essential Tips for Modeling Diet-Induced Obesity in Mice

Multiple inbred mouse models serve as powerful tools to study the genetics, underlying mechanisms, and therapies for human metabolic disorders.  During this webinar, you will  learn about applications and considerations for using diet-induced obesity (DIO) mouse models for modeling aspects of human metabolic disease. Join us as we discuss the following topics:

(1) Advantages of using DIO models for metabolic research

(2) Understanding how inbred strain background and substrain background alone can dramatically alter the development of obesity

(3) Identifying  the characteristic features of DIO models including  age and sex at phenotype onset and severity and progression of disease development

(4) Environmental factors and husbandry strategies which will promote stability of phenotypes (5)Data from proof-of-principle preclinical efficacy studies using reference compounds.

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