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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482245
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2019-05-24)
Alternate IDs: RGD_6482245, 6482245, RRRC_280, RRRC_0280, RRRC_00280
Notes: SS/JrHsd embryos were microinjected with rat alpha1 Na,K-ATPase promoter (-1288 5 flanking regulatory region isolated from Sprague Dawley genomic library); transgene cDNA: Dahl R alpha1 Na,K-ATPase Rat Resource and Research Center
Proper citation: RRID:RRRC_00280 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482292
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo (as of 2017-08-08)
Alternate IDs: RGD_6482292, 6482292, RRRC_297, RRRC_0297, RRRC_00297
Notes: This strain expresses LacZ ubiquitously driven by the ROSA26 promoter established at Jichi Medical School. Rat Resource and Research Center
Proper citation: RRID:RRRC_00297 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6478789
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery (as of 2018-07-16)
Alternate IDs: RGD_6478789, 6478789, RRRC_296, RRRC_0296, RRRC_00296
Notes: Transgene prepared from cDNA fragment of EGFP derived from pEGFP vector (No. 6077-1, Clontech Laboratories, Inc., Palo Alto, CA) and pCXN2 expression vector containing cytomegalovirus enhancer, chicken b-actin enhancer-promoter and rabbit b-globin poly(A) signal. Rat Resource and Research Center
Proper citation: RRID:RRRC_00296 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9590284
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-02-05)
Alternate IDs: RGD_9590284, 9590284, RRRC_637, RRRC_0637, RRRC_00637
Notes: SS/JrHsd embryos were microinjected with 1.57 kb human CETP cDNA construct into pSV-SPORT1 with human ApoC3 promoter Rat Resource and Research Center
Proper citation: RRID:RRRC_00637 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7247286
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-02-05)
Alternate IDs: RGD_7247286, 7247286, RRRC_636, RRRC_0636, RRRC_00636
Notes: F344/NHsd embryos were microinjected with a DNA construct containing human beta amyloid precursor protein (APP), Swedish (Swe) double mutation (K670N-M671L) and Indiana (Ind) single autosomal dominant mutation (V642F). The transgene is driven by an ubiquitin-C promoter. Homozygous transgenic rats exhibit approximately 2.9-fold more expression of APP mRNA than wild-type rats. Rat Resource and Research Center
Proper citation: RRID:RRRC_00636 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13592605
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2019-03-18)
Alternate IDs: RGD_13592605, 13592605, RRRC_797, RRRC_0797, RRRC_00797
Notes: The transgene consists of a SpeI fragment from plasmid pCAG-loxPSTOPloxP-ZsGreen (Addgene plasmid #51269, donated by Pawel Pelczar). Hemizygous animals contain approximately 4 copies of the transgene integrated at a site on Chromosome 2. Rat Resource and Research Center
Proper citation: RRID:RRRC_00797 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10401204
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Sperm (as of 2017-05-31)
Alternate IDs: RGD_10401204, 10401204, RRRC_658, RRRC_0658, RRRC_00658
Notes: Cre gene was introduced immediately before the ATG of the mouse choline acetyltransferase (Chat) gene in BAC RP23-246B12. This strain is estimated to carry 6 copies of the transgene at the integration site. Rat Resource and Research Center
Proper citation: RRID:RRRC_00658 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10412329
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2019-03-18)
Alternate IDs: RGD_10412329, 10412329, RRRC_773, RRRC_0773, RRRC_00773
Notes: The transgene expresses BAC transgenic using rat parvalbumin promoter to express Cre recombinase in parvalbumin expressing neurons Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00773 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13446407
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery (as of 2017-11-07)
Alternate IDs: RGD_13446407, 13446407, RRRC_688, RRRC_0688, RRRC_00688
Notes: The hemizygous rats have random insertion of calcium/calmodulin-dependent protein kinase II alpha (Camk2a)- cre/ERT2 (tamoxifen inducible Cre recombinase) transgene in the genome. This transgenic exhibits expression of cre/ERT2 fusion protein in neural populations where the mouse Camk2a promoter region found in the transgene is active. Rat Resource and Research Center
Proper citation: RRID:RRRC_00688 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13592604
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm; Cryorecovery (as of 2018-05-14)
Alternate IDs: RGD_13592604, 13592604, RRRC_785, RRRC_0785, RRRC_00785
Notes: These rats were created using BAC constructs consisting of the entire 144kb human LRRK2 locus containing the G2019S mutation and fused to a YPet reporter tag. Rat Resource and Research Center
Proper citation: RRID:RRRC_00785 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11667094
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_11667094, 11667094, RRRC_705, RRRC_0705, RRRC_00705
Notes: micro-injected with a ~6 kb transgenic cassette, which contained a CMV enhancer, chicken beta-actin promoter, the full-length cDNA encoding human complement factor H, and a rabbit beta-globin poly(A) sequence that had been isolated and purified from plasmid pCAGGS-human fH. Rat Resource and Research Center
Proper citation: RRID:RRRC_00705 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13462044
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_13462044, 13462044, RRRC_829, RRRC_0829, RRRC_00829
Notes: Pronuclear injection was used to introduce an expression cassette containing the Thy-1 enhancer and GCaMP6f protein coding sequence. GCaMP6f is a genetically encoded calcium indicator. It is a synthetic fusion of green fluorescent protein, calmodulin, and M13, a peptide sequence from myosin light-chain kinase. Rat Resource & Research Center
Proper citation: RRID:RRRC_00829 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=126781839
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery (as of 2024-01-05)
Alternate IDs: RGD_126781839, 126781839, RRRC_870, RRRC_0870, RRRC_00870
Notes: The 'docking site ready (DSR)' rat strain, or TARGAT /TM rat strain was generated using CRISPR/Cas9. With integrase, these TARGAT/DSR rats are used as embryo donors. TARGATT rat embryos will be microinjected with a mixture of TARGATT Cre DNA constructs containing mouse Olfr16 (MOR23) promoter, a fluorescent reporter mCherry in the Cre cassette linked by a T2A sequence. The Olfactory sensory neuronal lineage tissue-specific expression of a CreERT2 is also tamoxifen-dependent. Rat Resource and Research Center
Proper citation: RRID:RRRC_00870 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588593
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryorecovery (as of 2025-01-27)
Alternate IDs: RGD_9588593, 9588593, RRRC_751, RRRC_0751, RRRC_00751
Notes: The transgene expresses BAC transgenic using rat GAD1 promoter to express Cre recombinase in GABAergic neurons Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00751 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=126781841
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryorecovery (as of 2024-01-10)
Alternate IDs: RGD_126781841, 126781841, RRRC_872, RRRC_0872, RRRC_00872
Notes: The CRISPR/Cas9 system was injected to the Crl:CD(SD)embryo to induce the knock-in Cre-ERT2 cassette at the 3' end of Mnx1 (HB9) gene linked by 2A peptide. This model is used to lineage tracing of motor neurons by tissue specific expression of creERT2 Rat Resource and Research Center
Proper citation: RRID:RRRC_00872 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=126781842
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryorecovery (as of 2024-01-05)
Alternate IDs: RGD_126781842, 126781842, RRRC_873, RRRC_0873, RRRC_00873
Notes: The CRISPR/Cas9 system was injected to the Crl:CD(SD)embryo to induce the knock-in Cre-ERT2 cassette at the 3' end of Drd1 (Drd1a) gene linked by 2A peptide. This model is used to lineage tracing of dopamine D1 receptor expressing neurons Rat Resource and Research Center
Proper citation: RRID:RRRC_00873 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11084925
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_11084925, 11084925, RRRC_754, RRRC_0754, RRRC_00754
Notes: Transgene: human CD59 gene (cDNA) under control of alpha-globin regulatory elements (alpha-globin promoter and alpha hemoglobin locus control region). Upon administration of intermedilysin (ILY), cells expressing human CD59 will be selectively ablated Rat Resource and Research Center
Proper citation: RRID:RRRC_00754 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=56677892
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2024-01-05)
Alternate IDs: RGD_56677892, 56677892, RRRC_876, RRRC_0876, RRRC_00876
Notes: The 'docking site ready (DSR)' rat strain, or TARGAT /TM rat strain was generated using CRISPR/Cas9. With integrase, these TARGAT/DSR rats are used as embryo donors. TARGATT rat embryos will be microinjected with a mixture of TARGATT Cre DNA constructs containing human GFAP promoter, a fluorescent reporter mCherry in the Cre cassette linked by a T2A sequence. The astrocyte tissue-specific expression of a CreERT2 is also tamoxifen-dependent. Rat Resource and Research Center
Proper citation: RRID:RRRC_00876 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588578
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2017-05-31)
Alternate IDs: RGD_9588578, 9588578, RRRC_758, RRRC_0758, RRRC_00758
Notes: The transgene contains BAC transgenic using rat dopamine transporterSlc6a3 (DAT) promoter to express Cre recombinase in dopaminergic neurons Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00758 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10401208
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Sperm (as of 2019-02-20)
Alternate IDs: RGD_10401208, 10401208, RRRC_699, RRRC_0699, RRRC_00699
Notes: The strain was coinjected with two transgenes: one contains the human amyloid beta (A4) precursor protein (hAPP) gene with the Swedish mutation (K595N/M596L) driven by mouse prion promoter (Prp). The other contains the human presenilin 1 gene (PS1) with a deletion of exon 9, also driven by the mouse prion promoter (Prp). Based on segregation patterns, it is believed that the two transgenes have integrated at the same chromosomal site. Rat Resource and Research Center
Proper citation: RRID:RRRC_00699 Copy
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