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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695033
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_14695033, 14695033, RRRC_843, RRRC_0843, RRRC_00843
Notes: A CAG-Flpe cassette was injected into SD zygote to generate this line. The integration site is not determined.This transgenic line could be used to mate with other rat models that contains FRT sites to remove the cassette that is flanked by those FRT sites. Rat Resource and Research Center
Proper citation: RRID:RRRC_00843 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155260362
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_155260362, 155260362, RRRC_969, RRRC_0969, RRRC_00969
Notes: rat strain designed to express Cas9 under the control of the rat Ddx4 (Vasa) regulatory elements while also retaining expression of Ddx4. The strategy entailed insertion of a P2A sequence followed by human-codon-optimized Cas9 coding sequences with nuclear localization signals near the C-terminus of the rat Ddx4 (Vasa) gene. Animals express Cas9 in the testis in the spermatogonial layer and in meiosis stages with 4N DNA content. Strain catalyzes high levels of Active Genetic Gene conversion when paired with certain Active Genetic cassettes. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin URL: Doi:10.1101/2022.08.30.505951
URL: Doi:10.1101/2022.08.30.505951 Rat Resource and Research Center
Proper citation: RRID:RRRC_00969 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10401195
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Sperm; Cryorecovery
Alternate IDs: RGD_10401195, 10401195, RRRC_689, RRRC_0689, RRRC_00689
Notes: Random insertion of a Cre inducible expression cassette, controlled by the CAG promoter. LacZ is expressed constitutively, GFP only after Cre mediated recombination Rat Resource and Research Center
Proper citation: RRID:RRRC_00689 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10401212
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm; Cryorecovery
Alternate IDs: RGD_10401212, 10401212, RRRC_700, RRRC_0700, RRRC_00700
Notes: Human NIPA1G106R mutation is made by site-directed mutagenesis and then inserted into Thy1.2-promotor cassette. Transgenic vector is injected into fertilized eggs to produce 2 independent lines (A, B) Rat Resource and Research Center
Proper citation: RRID:RRRC_00700 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=149735896
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_149735896, 149735896, RRRC_942, RRRC_0942, RRRC_00942
Notes: Random insertion of transgene consisting of firefly luciferase-T2A-mCherry driven by regulatory elements of rat Col2a1, for conditional expression in chondrogenic cells. Both reporters are expressed by chondrogenic cells, leading to bioluminescence within regions of active chondrogenesis upon injecting rats with D-luciferin Rat Resource and Research Center
Proper citation: RRID:RRRC_00942 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588595
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_9588595, 9588595, RRRC_750, RRRC_0750, RRRC_00750
Notes: The transgene expresses BAC transgenic using rat GlyT2 (Slc6a5) promoter to express Cre recombinase in glycinergic neurons Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00750 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11084931
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_11084931, 11084931, RRRC_757, RRRC_0757, RRRC_00757
Notes: Transgene: RIP7-RLuc-YFP. This transgene expresses a renilla luciferase-YFP fusion protein under control of the rat insulin 2 gene promoter (RIP7). Rat Resource and Research Center
Proper citation: RRID:RRRC_00757 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=149735366
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_149735366, 149735366, RRRC_879, RRRC_0879, RRRC_00879
Notes: A transgenic line carrying random insertion of transgene cassette CAG-LSL-GFP-LacZ (LSL: loxp-Stop-Loxp). It is used as a Cre reporter/test line expressing GFP and lacZ. Used as lineage tracing tool rat line by mating with tissue specific cre or cre/ERT2 line Deposited at Rat Resource and Research Center
Proper citation: RRID:RRRC_00879 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588581
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_9588581, 9588581, RRRC_759, RRRC_0759, RRRC_00759
Notes: The transgene contains reporter rat expressing beta-galactosidase in cFos expressing cells Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00759 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588583
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_9588583, 9588583, RRRC_760, RRRC_0760, RRRC_00760
Notes: The transgene contains Cre recombinase expressed from cFos promoter and controllable by Tet activator/repressor Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00760 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588587
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_9588587, 9588587, RRRC_761, RRRC_0761, RRRC_00761
Notes: The transgene expresses TetR using "ubiquitous" promoter; to be used in combination with TetO containing rats or viral vectors Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00761 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588589
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_9588589, 9588589, RRRC_735, RRRC_0735, RRRC_00735
Notes: The transgene expresses TetR using "ubiquitous" promoter; to be used in combination with TetO containing rats or viral vectors Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00735 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13441557
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_13441557, 13441557, RRRC_858, RRRC_0858, RRRC_00858
Notes: This strain was generated by microinjection of LE embyos with a BAC DNA containing the Cx3cr1-cre/ERT2 transgene which is composed of cre/ERT2 recombinase gene driven by the rat genomic Cx3cr1promoter. Rat Resource and Research Center
Proper citation: RRID:RRRC_00858 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11040565
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm; Cryorecovery
Alternate IDs: RGD_11040565, 11040565, RRRC_746, RRRC_0746, RRRC_00746
Notes: random insertion of a transgene carrying orange fluorescent protein (OFP) driven by the CAG promoter Rat Resource and Research Center
Proper citation: RRID:RRRC_00746 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155641233
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_155641233, 155641233, RRRC_639, RRRC_0639, RRRC_00639
Notes: This transgenic strain carries a copy of mouse Rhodopsin gene with a proline to histidine substitution at codon 23 (c.68C>A). Retinal Degeneration Rat Model Resource ,Rat Resource and Research Center
Proper citation: RRID:RRRC_00639 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245523
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_7245523, 7245523, RRRC_635, RRRC_0635, RRRC_00635
Notes: the transgene overexpressing duble-mutated human alpha-synuclein (A53T and A30P) under the control of rat tyrosine hydroxylase (Th)promoter was microinjected into SD ovocytes to generate 3 transgenic rat lines. This line, MA4, shows learning and memory deficits beginning at 9 months of age. It is a model for dementia with Lewy bodies. Rat Resource and Research Center
Proper citation: RRID:RRRC_00635 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245521
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_7245521, 7245521, RRRC_634, RRRC_0634, RRRC_00634
Notes: the transgene overexpressing double-mutated human alpha-synuclein (A53T and A30P) under the control of rat tyrosine hydroxylase (Th)promoter was microinjected into SD ovocytes to generate 3 transgenic rat lines. The MA3 line has pre-symptomatic olfactory deficits (beginning at 6 months of age) and motor deficits starting at a later age (19 months of age). Rat Resource and Research Center
Proper citation: RRID:RRRC_00634 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=629006610
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo (as of 2025-11-06)
Alternate IDs: RGD_629006610, 629006610, RRRC_1001, RRRC_01001
Notes: Genetic Alteration(s):human ACE2 gene under expression of the human ACE2 promoter. Thirty (30) copies of the transgene are randomly integrated into an as yet unknown insertion site. Deposited at Rat Resource and Research Center
Proper citation: RRID:RRRC_01001 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=626189117
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryorecovery (as of 2025-09-03)
Alternate IDs: RGD_626189117, 626189117, RRRC_539, RRRC_0539, RRRC_00539
Notes: This strain was created by crossing “SD-Tg(Rho*S334X)3Lav, RGD: 1358302,”( also known as, SD-Tg(S334ter)3Lav , homozygous for a mutated mouse rhodopsin transgene Rho S334ter-3) with “NTac:NIH-Foxn1rnu, RGD: 7246928,” (also known as NTac:NIH-Whn (NIH nude) males (foxn1-/-). By selective breeding, all animals of this strain (RRRC#539) are homozygous for the rhodopsin mutation, and homo- or hemizygous for the foxn1 mutation. Rat Resource and Research Center
Proper citation: RRID:RRRC_00539 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=629006509
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryorecovery (as of 2025-10-30)
Alternate IDs: RGD_629006509, 629006509, RRRC_1051, RRRC_01051
Notes: These rats produce human familial CAA Dutch E22Q mutant amyloid APPB2-protein in brain and develop arteriolar CAA type-2. The deposition of fibrillar APPB2 promotes arteriolar smooth muscle cell loss and cerebral microhemorrhages that can be detected by magnetic resonance imaging and confirmed by histopathology. Random integration of a transgene consisting of 2.1 kb of human APP (isoform 770) cDNA carrying the Dutch E693Q mutation cloned between exons II and IV of a Thy1.2 expression cassette. This leads to expression of chimeric mutant human A beta PP under control of the neuronal specific Thy1.2 promoter. The integration site of the transgene is unknown. Rat Resource and Research Center
Proper citation: RRID:RRRC_01051 Copy
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