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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Authority Record Last Update Mentions Count
C57BL/6N-Selenoktm1a(EUCOMM)Wtsi/Mmucd
 
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RRID:MMRRC_037032-UCD Mus musculus Research areas: ; Mutation Type: Targeted Mutation ; Collection: BaSH EUCOMM decreased lean body mass [MP:0003961] decreased circulating creatinine level [MP:0005554] |Selenok| 037032-UCD Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:21677750
PMID:27626380
MMRRC_37032-UCD, MMRRC_037032, MMRRC_3732 MMRRC 2026-09-26 06:56:27 0
B6.129S1-Aqp9tm1Nlsn/Mmjax
 
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RRID:MMRRC_037111-JAX Mus musculus Research areas: Diabetes, Metabolism, Obesity; Mutation Type: Targeted Mutation ; Collection: increased circulating triglyceride level [MP:0001552]| increased circulating glycerol level [MP:0003443]| abnormal erythrocyte physiology [MP:0003656]| abnormal erythrocyte osmotic lysis [MP:0003657]| decreased susceptibility to parasitic infection [MP:0005026]| decreased circulating glucose level [MP:0005560] Aqp9 037111-JAX Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:17360690 MMRRC_37111-JAX, MMRRC_037111, MMRRC_37111 MMRRC 2026-09-26 06:56:28 0
B6.129S1-Artm1(AR)Dmr/Mmnc
 
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RRID:MMRRC_037109-UNC Mus musculus Research areas: Cancer, Endocrine Deficiency, Models for Human Disease, Neurobiology, Reproduction, Research Tools; Mutation Type: Targeted Mutation ; Collection: increased body weight [MP:0001260]| increased percent body fat/body weight [MP:0005458]| increased prostate gland tumor incidence [MP:0010357] ArAR 037109-UNC Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:16601069 MMRRC_37109-UNC, MMRRC_037109, MMRRC_3719 MMRRC 2026-09-26 06:56:28 0
C57BL/6N-Atm1Brd Mrps5tm1a(EUCOMM)Wtsi/Mmucd
 
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RRID:MMRRC_037023-UCD Mus musculus Research areas: ; Mutation Type: Targeted Mutation ; Collection: BaSH EUCOMM |Mrps5|| 037023-UCD Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:21677750 MMRRC_37023-UCD, MMRRC_037023, MMRRC_3723 MMRRC 2026-09-26 06:56:26 0
C57BL/6N-Gsk3atm1a(EUCOMM)Wtsi/Mmucd
 
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RRID:MMRRC_037021-UCD Mus musculus Research areas: ; Mutation Type: Targeted Mutation ; Collection: Sanger EUCOMM Collection cleft palate [MP:0000111]| decreased body length [MP:0001258]| decreased body weight [MP:0001262]| decreased circulating glycerol level [MP:0003442]| decreased lumbar vertebrae number [MP:0004647]| decreased circulating glucose level [MP:0005560]| decreased total body fat amount [MP:0010025]| increased sacral vertebrae number [MP:0010101]| wide metopic suture [MP:0030431] |Gsk3a| 037021-UCD Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:21677750 MMRRC_37021-UCD, MMRRC_037021, MMRRC_3721 MMRRC 2026-09-26 06:56:26 0
NOD.Cg-H2h4 Tg(tetO-Tcra)1Doi/HbmMmmh
 
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RRID:MMRRC_037148-MU Mus musculus Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874] ||Tcra| 037148-MU Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:21220693
PMID:23509363
MMRRC_37148-MU, MMRRC_037148, MMRRC_37148 MMRRC 2026-09-26 06:56:29 0
B6;129S2-Drd3tm1Stl/Mmjax
 
Resource Report
Resource Website
RRID:MMRRC_037114-JAX Mus musculus Research areas: Neurobiology, Obesity; Mutation Type: Targeted Mutation ; Collection: abnormal body water content [MP:0000676]| hyperactivity [MP:0001399]| increased exploration in new environment [MP:0001415]| abnormal cued conditioning behavior [MP:0001454]| abnormal food intake [MP:0005449]| increased susceptibility to weight gain [MP:0005455]| increased percent body fat/body weight [MP:0005458]| increased circulating leptin level [MP:0005669]| abnormal behavioral response to addictive substance [MP:0009748]| increased total body fat amount [MP:0010024] Drd3 037114-JAX Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:9354330 MMRRC_37114-JAX, MMRRC_037114, MMRRC_37114 MMRRC 2026-09-26 06:56:29 0
B6;129S4-Mns1tm1Jw/Mmjax
 
Resource Report
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1+ mentions
RRID:MMRRC_037095-JAX Mus musculus Research areas: Cell Biology, Developmental Biology, Models for Human Disease, Reproduction; Mutation Type: Targeted Mutation ; Collection: hydroencephaly [MP:0001891]| male infertility [MP:0001925]| abnormal epididymis morphology [MP:0002631]| asthenozoospermia [MP:0002675]| oligozoospermia [MP:0002687]| left pulmonary isomerism [MP:0003178]| decreased testis weight [MP:0004852]| abnormal spermatid morphology [MP:0006380]| abnormal sperm flagellum morphology [MP:0008892]| kinked sperm flagellum [MP:0009237]| short sperm flagellum [MP:0009239]| abnormal sperm mitochondrial sheath morphology [MP:0009832]| abnormal sperm axoneme morphology [MP:0009838]| lethality [MP:0010831]| incomplete penetrance [MP:0010854]| lung situs inversus [MP:0011050]| abnormal respiratory motile cilium morphology [MP:0030591] Mns1 037095-JAX Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:22396656 MMRRC_37095-JAX, MMRRC_037095, MMRRC_3795 MMRRC 2026-09-26 06:56:29 1
C57BL/6N-Atm1Brd Trmt2atm2a(EUCOMM)Wtsi/Mmucd
 
Resource Report
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RRID:MMRRC_037040-UCD Mus musculus Research areas: ; Mutation Type: Targeted Mutation ; Collection: BaSH EUCOMM |Trmt2a|| 037040-UCD Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:21677750 MMRRC_37040-UCD, MMRRC_037040, MMRRC_374 MMRRC 2026-09-26 06:56:27 0
NOD.Cg-Pdcd1tm1.1Shr Ifngtm1Ts H2h4/HbmMmmh
 
Resource Report
Resource Website
1+ mentions
Issue
RRID:MMRRC_037145-MU Mus musculus Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466]| abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874]| vasculitis [MP:0001864]| pancreas inflammation [MP:0001869]| increased retinal ganglion cell number [MP:0002983]| insulitis [MP:0004031]| increased susceptibility to autoimmune diabetes [MP:0004803]| increased regulatory T cell number [MP:0004973]| decreased B-1 B cell number [MP:0004978]| abnormal immune tolerance [MP:0005000]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348] |Pdcd1||Ifng|| 037145-MU Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC MMRRC_37145-MU, MMRRC_037145, MMRRC_37145 MMRRC 2026-09-26 06:56:29 1
B6.129S1-Artm3(AR)Dmr/Mmnc
 
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RRID:MMRRC_037118-UNC Mus musculus Research areas: Cancer, Endocrine Deficiency, Models for Human Disease, Neurobiology, Reproduction, Research Tools; Mutation Type: Targeted Mutation ; Collection: increased body weight [MP:0001260]| decreased tumor incidence [MP:0002052]| increased percent body fat/body weight [MP:0005458] Ar|AR| 037118-UNC Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:16601069 MMRRC_37118-UNC, MMRRC_037118, MMRRC_37118 MMRRC 2026-09-26 06:56:29 0
C57BL/6N-Zkscan17tm1a(EUCOMM)Wtsi/Mmucd
 
Resource Report
Resource Website
RRID:MMRRC_037045-UCD Mus musculus Research areas: ; Mutation Type: Targeted Mutation ; Collection: BaSH EUCOMM |Zkscan17| 037045-UCD Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:21677750 MMRRC_37045-UCD, MMRRC_037045, MMRRC_3745 MMRRC 2026-09-26 06:56:27 0
C57BL/6N-Tatdn3tm1a(EUCOMM)Wtsi Atm1Brd/Mmucd
 
Resource Report
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RRID:MMRRC_037037-UCD Mus musculus Research areas: ; Mutation Type: Targeted Mutation ; Collection: BaSH EUCOMM decreased blood urea nitrogen level [MP:0005566] |Tatdn3|| 037037-UCD Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:21677750
PMID:27626380
MMRRC_37037-UCD, MMRRC_037037, MMRRC_3737 MMRRC 2026-09-26 06:56:27 0
B6.129P2(Cg)-Izumo1rtm1.1Salb/Mmnc
 
Resource Report
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1+ mentions
RRID:MMRRC_037093-UNC Mus musculus Research areas: Cell Biology, Developmental Biology, Immunology and Inflammation, Reproduction; Mutation Type: Targeted Mutation ; Collection: female infertility [MP:0001926] Izumo1r 037093-UNC Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:23651732 MMRRC_37093-UNC, MMRRC_037093, MMRRC_3793 MMRRC 2026-09-26 06:56:28 2
C57BL/6N-Atm1Brd Trim29tm1a(EUCOMM)Wtsi/Mmucd
 
Resource Report
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RRID:MMRRC_037039-UCD Mus musculus Research areas: ; Mutation Type: Targeted Mutation ; Collection: BaSH EUCOMM |Trim29|| 037039-UCD Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:21677750
PMID:27626380
MMRRC_37039-UCD, MMRRC_037039, MMRRC_3739 MMRRC 2026-09-26 06:56:27 0
B6.129S1-Artm2(AR)Dmr/Mmnc
 
Resource Report
Resource Website
RRID:MMRRC_037108-UNC Mus musculus Research areas: Cancer, Endocrine Deficiency, Models for Human Disease, Neurobiology, Reproduction, Research Tools; Mutation Type: Targeted Mutation ; Collection: increased prostate gland tumor incidence [MP:0010357] Ar|AR| 037108-UNC Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:16601069 MMRRC_37108-UNC, MMRRC_037108, MMRRC_3718 MMRRC 2026-09-26 06:56:28 0
NOD.Cg-Ifngtm1Ts Ighmtm1Cgn H2h4/HbmMmmh
 
Resource Report
Resource Website
Issue
Issue
Issue
RRID:MMRRC_037144-MU Mus musculus Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874]| decreased bone mineral density [MP:0000063]| abnormal trabecular bone morphology [MP:0000130]| decreased compact bone thickness [MP:0000135]| enlarged heart [MP:0000274]| increased cell proliferation [MP:0000351]| abnormal intestinal epithelium morphology [MP:0000488]| abnormal spleen morphology [MP:0000689]| enlarged lymph nodes [MP:0000702]| abnormal skin condition [MP:0001191]| abnormal cardiovascular system physiology [MP:0001544]| abnormal humoral immune response [MP:0001800]| arrested B cell differentiation [MP:0001802]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| thymus hypoplasia [MP:0001823]| abnormal antigen presentation [MP:0001835]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| heart inflammation [MP:0001853]| myocarditis [MP:0001856]| kidney inflammation [MP:0001859]| abnormal lymphatic vessel morphology [MP:0001879]| premature death [MP:0002083]| abnormal respiratory system physiology [MP:0002133]| abnormal B cell differentiation [MP:0002144]| abnormal spleen marginal sinus morphology [MP:0002363]| abnormal B lymphocyte antigen presentation [MP:0002453]| decreased immunoglobulin level [MP:0002460]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| tubular nephritis [MP:0002704]| increased urine protein level [MP:0002962]| abnormal cytokine secretion [MP:0003009]| cardiac fibrosis [MP:0003141]| thrombocytopenia [MP:0003179]| small intestinal inflammation [MP:0003306]| increased susceptibility to induced arthritis [MP:0003724]| increased autoantibody level [MP:0003725]| abnormal compact bone morphology [MP:0003797]| abnormal PR interval [MP:0003901]| insulitis [MP:0004031]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| increased susceptibility to autoimmune diabetes [MP:0004803]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased spleen weight [MP:0004953]| increased osteoclast cell number [MP:0004984]| increased T cell number [MP:0005015]| decreased B cell number [MP:0005017]| abnormal response to infection [MP:0005025]| increased susceptibility to parasitic infection [MP:0005027]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| cachexia [MP:0005150]| decreased susceptibility to injury [MP:0005166]| abnormal pancreatic islet morphology [MP:0005215]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005559]| increased circulating glucose level [MP:0005616]| decreased susceptibility to type IV hypersensitivity reaction [MP:0006387]| abnormal T cell number [MP:0008071]| absent B cells [MP:0008075]| decreased CD4-positive [MP:0008079]| alpha beta T cell number [MP:0008127]| decreased CD8-positive [MP:0008171]| alpha-beta T cell number [MP:0008201]| decreased dendritic cell number [MP:0008211]| abnormal mature B cell morphology [MP:0008212]| absent follicular dendritic cells [MP:0008213]| decreased mature B cell number [MP:0008240]| absent mature B cells [MP:0008241]| absent immature B cells [MP:0008401]| abnormal spleen marginal zone macrophage morphology [MP:0008470]| abnormal metallophilic macrophage morphology [MP:0008495]| abnormal CD8 positive [MP:0009346]| alpha-beta intraepithelial T cell morphology [MP:0010965]| abnormal spleen B cell follicle morphology [MP:0012431]| increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466] Ighm||Ifng||| 037144-MU Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC PMID:23509363 MMRRC_37144-MU, MMRRC_037144, MMRRC_37144 MMRRC 2026-09-26 06:56:29 0
C57BL/6-Hprt1tm347(Ple155-icre/ERT2)Ems/Mmjax
 
Resource Report
Resource Website
RRID:MMRRC_037077-JAX Mus musculus Research areas: ; Mutation Type: Targeted Mutation ; Collection: Pleiades Promoter/CanEuCre no abnormal phenotype detected [MP:0002169] PCP2||Hprt1| 037077-JAX Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC MMRRC_37077-JAX, MMRRC_037077, MMRRC_3777 MMRRC 2026-09-26 06:56:28 0
C57BL/6-Hprt1tm351(Ple198-icre/ERT2)Ems/Mmjax
 
Resource Report
Resource Website
RRID:MMRRC_037081-JAX Mus musculus Research areas: ; Mutation Type: Targeted Mutation ; Collection: Pleiades Promoter/CanEuCre no abnormal phenotype detected [MP:0002169] SLC6A4||Hprt1| 037081-JAX Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC MMRRC_37081-JAX, MMRRC_037081, MMRRC_3781 MMRRC 2026-09-26 06:56:28 0
NOD.Cg-Cd40tm1Kik Ifngtm1Ts H2h4 Tg(tetO-Tcra)1Doi/HbmMmmh
 
Resource Report
Resource Website
Issue
RRID:MMRRC_037149-MU Mus musculus Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466]| decreased bone mineral density [MP:0000063]| decreased neutrophil cell number [MP:0000222]| enlarged spleen [MP:0000691]| enlarged lymph nodes [MP:0000702]| abnormal humoral immune response [MP:0001800]| decreased IgA level [MP:0001807]| no abnormal phenotype detected [MP:0002169]| abnormal thymus medulla morphology [MP:0002375]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| decreased IgE level [MP:0002492]| glomerulonephritis [MP:0002743]| increased urine protein level [MP:0002962]| increased anti-double stranded DNA antibody level [MP:0004762]| abnormal class switch recombination [MP:0004816]| decreased B cell number [MP:0005017]| decreased susceptibility to type II hypersensitivity reaction [MP:0005612]| decreased cerebral infarction size [MP:0006058]| increased follicular B cell number [MP:0008173]| absent germinal center B cells [MP:0008179]| increased marginal zone B cell number [MP:0008181]| increased transitional stage B cell number [MP:0008189]| abnormal B cell activation [MP:0008217]| absent spleen germinal center [MP:0008474]| decreased IgG1 level [MP:0008495]| decreased IgG2a level [MP:0008496]| decreased IgG2b level [MP:0008497]| decreased IgG3 level [MP:0008498]| abnormal thymus epithelium morphology [MP:0009544]| decreased platelet aggregation [MP:0009549]| decreased trabecular bone mass [MP:0010873]| decreased compact bone mass [MP:0010962]| renal glomerular immunoglobulin deposits [MP:0020519]| abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874] Cd40||Ifng|||| 037149-MU Targeted Mutation Mutant Mouse Resource and Research Center (MMRRC) MMRRC MMRRC_37149-MU, MMRRC_037149, MMRRC_37149 MMRRC 2026-09-26 06:56:29 0

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