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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=6142
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: transgene insertion C; David A Harris|prion protein
Genomic Alteration: transgene insertion C; David A Harris|targeted mutation 1; Charles Weissmann
Availability: embryo
Synonyms: STOCK Prnp<tm1Cwe> Tg(Prnp-PG14)1Dah/Cnrm. Tg(PG14-C)/Prnp0/0. STOCK Prnp<tm1Cwe> Tg(Prnp-PG14)CDah/Cnrm
Alternate IDs: SCR_006136
Notes: gene symbol note: transgene insertion C; David A Harris|prion protein; mutant strain: Tg(Prnp*)CDah|Prnp
Proper citation: RRID:IMSR_EM:06142 Copy
Issue Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=6326
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: interleukin 2 receptor; gamma chain|transgene insertion 1; Beatrice Perarnau|recombination activating gene 2|histocompatibility 2; class II antigen A; beta 1|transgene insertion 1; Daniel M Altmann|beta-2 microglobulin
Genomic Alteration: targeted mutation 1; Kazuo Sugamura|transgene insertion 1; Beatrice Perarnau|targeted mutation 1; Frederick W Alt|targeted mutation 1; Christophe Benoist and Diane Mathis|transgene insertion 1; Daniel M Altmann|targeted mutation 1; University of North Carolina
Availability: archived
Synonyms: SURE-L1/Rag2°/°GammaC°/°. STOCK Rag2<tm1Fwa> B2m<tm1Unc> H2-Ab1<tm1Doi> Il2rg<tm1Sug> Tg(HLA-A/H2-D/B2M)1Bpe Tg(HLA-DRA*0101.HLA-DRB1*0101)1Dma/Orl
Alternate IDs: SCR_006136
Notes: gene symbol note: interleukin 2 receptor; gamma chain|transgene insertion 1; Beatrice Perarnau|recombination activating gene 2|histocompatibility 2; class II antigen A; beta 1|transgene insertion 1; Daniel M Altmann|beta-2 microglobulin; mutant strain: Il2rg|Tg(HLA-A/H2-D/B2M)1Bpe|Rag2|H2-Ab1|Tg(HLA-DRA*0101;HLA-DRB1*0101)1Dma|B2m
Proper citation: RRID:IMSR_EM:06326 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=6943
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: beta-2 microglobulin|transgene insertion 1; Beatrice Perarnau|histocompatibility 2; class II antigen A; beta 1|transgene insertion 1; Daniel M Altmann|recombination activating gene 2|perforin 1 (pore forming protein)
Genomic Alteration: targeted mutation 1; University of North Carolina|transgene insertion 1; Beatrice Perarnau|targeted mutation 1; Christophe Benoist and Diane Mathis|transgene insertion 1; Daniel M Altmann|targeted mutation 1; Frederick W Alt|targeted mutation 1; Sandoz Pharmaceuticals
Availability: embryo
Synonyms: STOCK Rag2<tm1Fwa> B2m<tm1Unc> Prf1<tm1Sdz> H2-Ab1<tm1Doi> Tg(HLA-A/H2-D/B2M)1Bpe Tg(HLA-DRA*0101.HLA-DRB1*0101)1Dma/Orl
Alternate IDs: SCR_006136
Notes: gene symbol note: beta-2 microglobulin|transgene insertion 1; Beatrice Perarnau|histocompatibility 2; class II antigen A; beta 1|transgene insertion 1; Daniel M Altmann|recombination activating gene 2|perforin 1 (pore forming protein); mutant strain: B2m|Tg(HLA-A/H2-D/B2M)1Bpe|H2-Ab1|Tg(HLA-DRA*0101;HLA-DRB1*0101)1Dma|Rag2|Prf1
Proper citation: RRID:IMSR_EM:06943 Copy
Issue
https://brc.riken.jp/mus/RBRC06319
Source Database: RIKEN BioResource Research Center
Affected Genes: phenylalanine hydroxylase
Genomic Alteration: phenylalanine hydroxylase enu 2
Availability: embryo
Notes: gene symbol note: phenylalanine hydroxylase; mutant strain: Pah
Proper citation: RRID:IMSR_RBRC06319 Copy
Issue
https://brc.riken.jp/mus/RBRC06464
Source Database: RIKEN BioResource Research Center
Affected Genes: Fas cell surface death receptor
Genomic Alteration: lymphoproliferation
Availability: embryo
Notes: gene symbol note: Fas cell surface death receptor; mutant strain: Fas
Proper citation: RRID:IMSR_RBRC06464 Copy
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 9|toll-like receptor 2|toll-like receptor 4
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: embryo
Synonyms: TLR2/4/9 Triple KO C57BL/6. B6.129P2-Tlr2<tm1Aki> Tlr4<tm1Aki> Tlr9<tm1Aki>/Obs
Notes: gene symbol note: toll-like receptor 9|toll-like receptor 2|toll-like receptor 4; mutant strain|congenic strain: Tlr9|Tlr2|Tlr4
Proper citation: RRID:IMSR_OBS:21 Copy
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 4|toll-like receptor 2
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: embryo
Synonyms: B6.129P2-Tlr2<tm1Aki> Tlr4<tm1Aki>/Obs. "TLR2/4 double KO C57BL/6"
Notes: gene symbol note: toll-like receptor 4|toll-like receptor 2; mutant strain|congenic strain: Tlr4|Tlr2
Proper citation: RRID:IMSR_OBS:19 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: immunoglobulin heavy constant mu
Genomic Alteration: targeted mutation 1; University of Cologne
Availability: embryo
Synonyms: muMT<0>(muKO)
Alternate IDs: SCR_006136
Notes: gene symbol note: immunoglobulin heavy constant mu; mutant strain: Ighm
Proper citation: RRID:IMSR_EM:00001 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=29
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: beta-2 microglobulin
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: archived
Synonyms: beta2m<0>
Alternate IDs: SCR_006136
Notes: gene symbol note: beta-2 microglobulin; mutant strain: B2m
Proper citation: RRID:IMSR_EM:00029 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=158
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein
Genomic Alteration: targeted mutation 1; Charles Weissmann
Availability: embryo
Synonyms: B6;129S7-Prnp<tm1Cwe>/Cwe. B6;129S7-Prnp<tm1Cwe>. B6;129S7-Prnp<tm1Cwe>/CweIcbm. STOCK Prnp<tm1Cwe>. PrPC-KO. Prp-KO
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein; mutant strain: Prnp
Proper citation: RRID:IMSR_EM:00158 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=181
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein|transgene insertion a20; Charles Weissmann
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion a20; Charles Weissmann
Availability: embryo
Synonyms: Tga20. B6;129S7 Prnp<tm1Cwe>-Tg(Prnp)a20Cwe/Cwe. PrPC-KO. Tga20. B6;129S7-Prnp<tm1Cwe> Tg(Prnp)a20Cwe/CweIbcm. STOCK Prnp<tm1Cwe> Tg(Prnp)20Cwe
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein|transgene insertion a20; Charles Weissmann; mutant strain: Prnp|Tg(Prnp)a20Cwe
Proper citation: RRID:IMSR_EM:00181 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=180
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein|transgene insertion a19; Charles Weissmann
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion a19; Charles Weissmann
Availability: embryo
Synonyms: PrPC-KO. Tga19. B6;129S7 Prnp<tm1Cwe>-Tg(Prnp)a19Cwe/Cwe. Tga19. STOCK Prnp<tm1Cwe> Tg(Prnp)19Cwe. B6;129S7-Prnp<tm1Cwe> Tg(Prnp)a19Cwe/CweIbcm
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein|transgene insertion a19; Charles Weissmann; mutant strain: Prnp|Tg(Prnp)a19Cwe
Proper citation: RRID:IMSR_EM:00180 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=178
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein|transgene insertion 33; Charles Weissmann
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion 33; Charles Weissmann
Availability: embryo
Synonyms: PrPC-KO.Tg33. Tg33. B6;129S7-Prnp<tm1Cwe> Tg(Lck-Prnp)33Cwe/CweIbcm. B6;129S7 Prnp<tm1Cwe>-Tg(Lck-Prnp)33Cwe/Cwe. STOCK Prnp<tm1Cwe> Tg(Lck-Prnp)33Cwe
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein|transgene insertion 33; Charles Weissmann; mutant strain: Prnp|Tg(Lck-Prnp)33Cwe
Proper citation: RRID:IMSR_EM:00178 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=754
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: beta-2 microglobulin|histocompatibility 2; D region locus 1|histocompatibility 2; K1; K region|CD3 antigen; epsilon polypeptide
Genomic Alteration: targeted mutation 1; University of North Carolina|targeted mutation 1; Beatrice Perarnau|targeted mutation 1; Bernard Malissen
Availability: embryo
Synonyms: B6.Cg-B2m<tm1Unc> Cd3e<tm1Mal> H2-K1<tm1Bpe> H2-D1<tm1Bpe>/Orl. TetraKO - CD3- and MHC class I-
Alternate IDs: SCR_006136
Notes: gene symbol note: beta-2 microglobulin|histocompatibility 2; D region locus 1|histocompatibility 2; K1; K region|CD3 antigen; epsilon polypeptide; mutant strain: B2m|H2-D1|H2-K1|Cd3e
Proper citation: RRID:IMSR_EM:00754 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=430
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: apolipoprotein E|T cell receptor beta chain
Genomic Alteration: targeted mutation 1; University of North Carolina|targeted mutation 1; Peter Mombaerts
Availability: embryo
Synonyms: apolipoprotein E KO and TCRbeta KO
Alternate IDs: SCR_006136
Notes: gene symbol note: apolipoprotein E|T cell receptor beta chain; mutant strain: Apoe|Tcrb
Proper citation: RRID:IMSR_EM:00430 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1143
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: transgene insertion 1; University of Cologne
Genomic Alteration: transgene insertion 1; University of Cologne
Availability: embryo
Synonyms: B6.129-Tg(Mx1-cre)1Cgn. B6-Mx1-Cre. B6.129-TgN(Mx1-Cre)1Cgn. B6.Cg-Tg(Mx1-cre)1Cgn/CgnIbcm. B6.Cg-Tg(Mx1-cre)1Cgn. B6-Tg(Mx1-cre)1Cgn/CgnIbcm
Alternate IDs: SCR_006136
Notes: gene symbol note: transgene insertion 1; University of Cologne; mutant strain: Tg(Mx1-cre)1Cgn
Proper citation: RRID:IMSR_EM:01143 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1219
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: insulin I
Genomic Alteration: targeted mutation 1; Jacques Jami
Availability: embryo
Synonyms: Ins/1_129
Alternate IDs: SCR_006136
Notes: gene symbol note: insulin I; mutant strain: Ins1
Proper citation: RRID:IMSR_EM:01219 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1836
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein|transgene insertion F13; Zurich
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion F13; Zurich
Availability: embryo
Synonyms: TgF13/Prnp<o/+>. F13. B6.Cg-Prnp<tm1Cwe> Tg(L7-Prnp)F13/Cnrm
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein|transgene insertion F13; Zurich; mutant strain: Prnp|Tg(Pcp2-Prnp)F13Zbz
Proper citation: RRID:IMSR_EM:01836 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1828
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein|transgene insertion F332; Zurich
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion F332; Zurich
Availability: embryo
Synonyms: Prnp<tm1>-Tg(PrPdelta134)332Zbz. B6.Cg-Prnp<tm1Cwe> Tg(L7-Prnp)F332/Cnrm. F332
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein|transgene insertion F332; Zurich; mutant strain: Prnp|Tg(Pcp2-Prnp)F332Zbz
Proper citation: RRID:IMSR_EM:01828 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1824
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein|transgene insertion E330; Zurich
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion E330; Zurich
Availability: embryo
Synonyms: B6.Cg-Prnp<tm1Cwe> Tg(L7-Prnp)E330. E330
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein|transgene insertion E330; Zurich; mutant strain: Prnp|Tg(Pcp2-Prnp)E330Zbz
Proper citation: RRID:IMSR_EM:01824 Copy
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