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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054447
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: 10054447
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Rorc gene of LEW/NCrl rat embryos. The resulting mutation is a 59-bp deletion in the Rorc gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_10054447 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=152975964
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 152975964
Notes: Full gene inversion of the rat F8 gene introduced by CRISPR/Cas9, to DahlSS background rats. This inversion causes a premature stop codon 3 amino acids into the protein. F8 activity in rats, homozygous for the mutation, is undetectable. Contact MCW Rat Distribution at [email protected]
Proper citation: RRID:RGD_152975964 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054459
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: 10054459
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Sirt3 gene of T2DN/Mcwi rat embryos. The resulting mutation is a 31-bp deletion in the Sirt3 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_10054459 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054292
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: 10054292
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Arhgef11 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 17-bp deletion in the Arhgef11 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_10054292 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=152985526
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 152985526
Notes: A 7-bp deletion in exon 1 of the Cdkn2a (p16) gene was introduced by the CRISPR/Cas9. Genetic background is Iar:Wistar-Imamichi (Institute for Animal Reproduction) (RGD:125097496). Introducing the deletion mutation in the Cdkn2a (p16) gene into the background of DMD rats (muscular dystrophy model rats) improves muscle pathology. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_152985526 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155663559
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2022-11-28)
Alternate IDs: 155663559
Notes: CRISPR/Cas9 technology was used to insert an IRES for iCre expression after the final coding sequence of exon 6 of the rat Gcg gene, before the 3' UTR. Strain has been deposited to RRRC(RRRC:00983, RGD:155663560)
Proper citation: RRID:RGD_155663559 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10002782
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 10002782
Notes: Spontaneous mutation in the colony of SHR/OlaIpcv in Prague.
Proper citation: RRID:RGD_10002782 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1302678
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2024-09-24)
Alternate IDs: 1302678
Notes: Strain originated from Japan SLC, Inc, Shizuoka, Japan. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_1302678 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290082
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2290082, 2290082, RRRC_425, RRRC_0425, RRRC_00425
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 7th intron of the Brinp3 gene. Rat Resource & Research Center
Proper citation: RRID:RRRC_00425 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290166
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2290166, 2290166, RRRC_424, RRRC_0424, RRRC_00424
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 18th exon of the Plcb3 gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00424 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290056
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2290056, 2290056, RRRC_423, RRRC_0423, RRRC_00423
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169).This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 4th intron of the Rbed1 gene. Rat Resource & Research Center
Proper citation: RRID:RRRC_00423 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1642364
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_1642364, 1642364, RRRC_421, RRRC_0421, RRRC_00421
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. N26K mutation is generated from the codon change AAC/AAA. Rat Resource and Research Center
Proper citation: RRID:RRRC_00421 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290113
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2290113, 2290113, RRRC_387, RRRC_0387, RRRC_00387
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169).This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the Fam19a2 gene. Rat Resource & Research Center
Proper citation: RRID:RRRC_00387 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2292451
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2292451, 2292451, RRRC_386, RRRC_0386, RRRC_00386
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the Stxbp5l gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00386 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290078
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2290078, 2290078, RRRC_385, RRRC_0385, RRRC_00385
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169).This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 8th intron of the Myo9a gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00385 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=153298963
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_153298963, 153298963, RRRC_963, RRRC_0963, RRRC_00963
Notes: These mutants were found in Sprague-Dawley rats at University of Puebla in 1989 and donated by John Svaren to RRRC now are maintained at RRRC Rat Resource and Research Center
Proper citation: RRID:RRRC_00963 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1642439
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_1642439, 1642439, RRRC_419, RRRC_0419, RRRC_00419
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. Y297Stop mutation is generated from the codon change TAC/TAA. Rat Resource and Research Center
Proper citation: RRID:RRRC_00419 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1642276
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_1642276, 1642276, RRRC_418, RRRC_0418, RRRC_00418
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. N152K mutation is generated from the codon change AAT/AAA. Rat Resource and Research Center
Proper citation: RRID:RRRC_00418 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1642277
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_1642277, 1642277, RRRC_416, RRRC_0416, RRRC_00416
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. F475L mutation is generated from the codon change TTC/CTC. Rat Resource and Research Center
Proper citation: RRID:RRRC_00416 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1599758
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: RGD_1599758, 1599758, RRRC_415, RRRC_0415, RRRC_00415
Notes: Male founders were injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups were genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. The E124D mutation was generated from the codon change GAG/GAT. Rat Resource and Research Center
Proper citation: RRID:RRRC_00415 Copy
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