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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156212871
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Live Animals (as of 2023-02-14)
Alternate IDs: 156212871
Notes: An inbred strain derived from the Heterogeneous Stock by selective inbreeding more than 20 generations for spontaneous renal agenesis.
Proper citation: RRID:RGD_156212871 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156406412
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2024-08-06)
Alternate IDs: 156406412
Notes: These are re-derived rats of from HTX/Kyo and maintained at Medical College of Wisconsin.1981 by Kohn from institutional albino rats of unknown origin at University of Texas. From Juntendo University to Kyoto University in 1992. RGD HRDP, contact Hybrid Rat Diversity program at
[email protected]
Proper citation: RRID:RGD_156406412 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430077
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-24)
Alternate IDs: 156430077
Notes: This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP
Proper citation: RRID:RGD_156430077 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430110
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-24)
Alternate IDs: 156430110
Notes: Embryo-rederived from breeder stock BXH12-1/Cub provided by Dr. Kren from Charles University, Department of Biology, Prague, Czech Republic, maintained at Medical College of Wisconsin RGD HRDP, contact HRDP
Proper citation: RRID:RGD_156430110 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=151347605
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 151347605
Notes: CRISPR-Cas9 technique was used to generate DDAH1-/- rats on Sprague-Dawley background. Genome deletion in exon 1 was confirmed by PCR analysis with the primers:DDAH1-F (5'-GCGCTGCTCTCGGGAAGA-3') and DDAH1-R (5'-GGGTGATGAGGGCGGTCT-3').
Proper citation: RRID:RGD_151347605 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156420145
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-24)
Alternate IDs: 156420145
Notes: Embryo-rederived from breeder stock HXB7/Ipcv provided by Pravenec and Kren from the Prague colonies, maintained at Medical college of Wisconsin. RGD HRDP, contact Hybrid Rat Diversity Panel at
[email protected]
Proper citation: RRID:RGD_156420145 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156420144
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-24)
Alternate IDs: 156420144
Notes: Embryo-rederived from breeder stock HXB1/Ipcv provided by Pravenec and Kren from the Prague colonies, maintained at Medical college of Wisconsin. RGD HRDP, contact Hybrid Rat Diversity Panel at
[email protected]
Proper citation: RRID:RGD_156420144 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156420148
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-24)
Alternate IDs: 156420148
Notes: Embryo-rederived from breeder stock HXB18/Ipcv provided by Pravenec and Kren from the Prague colonies, maintained at Medical college of Wisconsin. RGD HRDP, contact Hybrid Rat Diversity Panel at
[email protected]
Proper citation: RRID:RGD_156420148 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=291492855
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 291492855
Notes: Transgenic Sprague Dawley rats were generated by injecting the linearized
fragment of the CosSHa.tet vector containing the full-length, non-mutant
human DISC1 as transgene with the polymorphisms F607 and C704, under the control of the Syrian hamster prion protein promoter, into pronuclei of Sprague Dawley rats.
Proper citation: RRID:RGD_291492855 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430103
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-24)
Alternate IDs: 156430103
Notes: This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP
Proper citation: RRID:RGD_156430103 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430102
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-24)
Alternate IDs: 156430102
Notes: This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP
Proper citation: RRID:RGD_156430102 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430101
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-24)
Alternate IDs: 156430101
Notes: This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP
Proper citation: RRID:RGD_156430101 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430109
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-24)
Alternate IDs: 156430109
Notes: This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP
Proper citation: RRID:RGD_156430109 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155782909
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 155782909
Notes: SS/JrHsdMcwi were crossed with SS-3BN/Mcwi, rats from F1 were intercrossed and genotyped to select the congenic strain carrying introgressed chromosome 3 from SS to BN. Contact MCW rat distribution at [email protected] for availability.
Proper citation: RRID:RGD_155782909 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156362762
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2024-08-06)
Alternate IDs: 156362762
Notes: These are re-derived rats of from RCS/LavRrrc and maintained at Medical College of Wisconsin. Originally developed before 1965 by Sidman from stock obtained from Sorsby of the Royal College of Surgeons, London. Then to University of California- San Francisco, School of Medicine, deposited to Rat Resource & Research Center. RGD HRDP, contact Hybrid Rat Diversity Program at
[email protected]
Proper citation: RRID:RGD_156362762 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155791425
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 155791425
Notes: The IL2Rg gene was targeted in the SS/JrHsdMcwi rat by
TALEN injection into single-cell rat embryos. Once established, a homozygous (RGD:12790632) female rat from the SSIL2Rg line was intercrossed with a homozygous SS.BN3 (RGD:1358154) male to yield heterozygous SS.BN3IL2Rg offspring (F1),
followed by brother-sister mating to yield homozygous SS.
BN3IL2Rg offspring by the F3 generation. This strain is Immunodeficient Ilrg (X-SCID) mutant consomic line.
Proper citation: RRID:RGD_155791425 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155260362
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 155260362
Notes: rat strain designed to express Cas9 under the control of the rat Ddx4 (Vasa) regulatory elements while also retaining expression of Ddx4. The strategy entailed insertion of a P2A sequence followed by human-codon-optimized Cas9 coding sequences with nuclear localization signals near the C-terminus of the rat Ddx4 (Vasa) gene. Animals express Cas9 in the testis in the spermatogonial layer and in meiosis stages with 4N DNA content. Strain catalyzes high levels of Active Genetic Gene conversion when paired with certain Active Genetic cassettes. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin URL: Doi:10.1101/2022.08.30.505951
URL: Doi:10.1101/2022.08.30.505951 RRRC
Proper citation: RRID:RGD_155260362 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430099
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-24)
Alternate IDs: 156430099
Notes: This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP
Proper citation: RRID:RGD_156430099 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155260361
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2022-10-06)
Alternate IDs: 155260361
Notes: This project entailed generation of a novel rat strain in which a P2A-Cas9-T2A-EGFP coding sequence was inserted at the stop codon of the rat Sycp1 gene for co-expression of Cas9 and EGFP under the control of the Sycp1 regulatory elements. Animals express Cas9 in the testis in the spermatogonial layer and in meiosis stages with 4N DNA content. Strain catalyzes high levels of Active Genetic Gene conversion when paired with certain Active Genetic cassettes. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin
URL: Doi:10.1101/2022.08.30.505951 from RRRC.
Proper citation: RRID:RGD_155260361 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155260363
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2022-10-06)
Alternate IDs: 155260363
Notes: rat strain in which the rat Cyp2e1 gene is humanized by insertion of a human CYP2E1 minigene (CYP2E1*) insert at the native start codon. The insert also included a CRISPR/Cas9 gene drive element to enable super-Mendelian inheritance of the modified allele when crossed to a rat expressing Cas9 in the germline. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin URL: Doi:10.1101/2022.08.30.505951 URL: Doi:10.1101/2022.08.30.505951
URL: URL: Doi:10.1101/2022.08.30.505951 RRRC
Proper citation: RRID:RGD_155260363 Copy
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