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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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WM/Nem Resource Report Resource Website |
RRID:RGD_127338473 | Rattus norvegicus | This Strain was from the National Institute of Genetics., Mishima, Japan to the research institute of Environmental Medicine, Nagoya University. | 127338473 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 127338473 | 2026-08-29 11:49:56 | 0 | |||||
|
LE-Arid1bem1Mcwi Resource Report Resource Website 1+ mentions |
RRID:RGD_14394518 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Arid1b gene of Crl:LE rat embryos. The resulting mutation is deletion of exon 4. Autism Rat Model Resource, Contact MCW rat distribution at [email protected] | 14394518 | mutant | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Sperm (as of 2025-02-20) | 14394518 | 2026-08-29 11:49:57 | 1 | |||||
|
SHR-Camk2n1em1Tja-/- Resource Report Resource Website |
RRID:RGD_19259464 | Rattus norvegicus | SHR-Camk2n1-/- knockout rats were generated on an SHR/NCrl background by microinjecting zinc-finger nuclease (ZFN) mRNA (Sigma), targeted to exon 1 of Camk2n1, into one-cell stage SHR/NCrl embryos that were implanted into pseudopregnant rats. Heterozygous progeny, from a founder harboring a 38bp deletion in Camk2n1, were intercrossed to generate homozygous knockout rats. | 19259464 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 19259464 | 2026-08-29 11:49:56 | 0 | |||||
|
SD-Cftrem1Ang Resource Report Resource Website |
RRID:RGD_126925992 | Rattus norvegicus | The CRISPR/Cas9 system targeting at exon 12 to create deletion at codon F508 was injected to the male pronucleus of the fertalized one-cell stage embryos collected from Crl:SD. The donor DNA generated a codon deletion at F508 and the creation of one NdeI restriction site for sequencing identification. | 126925992 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 126925992 | 2026-08-29 11:49:56 | 0 | |||||
|
SD-Cftrem2Ang Resource Report Resource Website |
RRID:RGD_126925994 | Rattus norvegicus | The CRISPR/Cas9 system targeting at exon 3 to create gene knock out was injected to the male pronucleus of the fertalized one-cell stage embryos collected from Crl:SD. The donor DNA generated a frameshift and the creation of one XbaI restriction site and a premature stop codon. Two knockout founders ( referred as MUKORAT8.3 and MUKORAT 6.4) exhibit no difference in phenotypes and were pooled for study. | 126925994 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 126925994 | 2026-08-29 11:49:56 | 0 | |||||
|
SD-Defb23em2MlitDefb26em2MlitDefb42em1Mlit Resource Report Resource Website |
RRID:RGD_38549357 | Rattus norvegicus | CRISPR/Cas9 system was used to generate the Defb23, Defb26 double-gene knockout (RGD:38549356) and Defb42 (RGD:38549355). The triple-KO rats were generated by crossing the heterozygous Defb23/26 mutation rats with the heterozygous Defb42 mutation rats. | 38549357 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 38549357 | 2026-08-29 11:49:56 | 0 | |||||
|
SD-Hamp em4Jfcol +/- Resource Report Resource Website 1+ mentions |
RRID:RGD_36174225 | Rattus norvegicus | Hamp KO, Sprague-Dawley rats were generated by Transposagen Biopharmaceuticals (Lexington, KY). Four different genetically engineered rat lines, each with different sized Hamp deletions (with or without concurrent insertions), were created using TALEN technology. SD-Hamp em4Jfcol +/- (RGD:36174225) is heterozygous carrying a 15-bp deletion in exon 2 of the rat Hamp gene Rat Resource & Research Center (RRRC) | 36174225 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-07-29) | 36174225 | 2026-08-29 11:49:55 | 1 | |||||
|
SD-Hamp em2Jfcol -/- Resource Report Resource Website 1+ mentions |
RRID:RGD_36174222 | Rattus norvegicus | Hamp KO, Sprague-Dawley rats were generated by Transposagen Biopharmaceuticals (Lexington, KY). Four different genetically engineered rat lines, each with different sized Hamp deletions (with or without concurrent insertions), were created using TALEN technology. SD-Hamp em2Jfcol -/- (RGD:36174222) is homozygous carrying a 230-bp deletion and a 1-bp insertion between exons 2 & 3 of both rat Hamp alleles. Rat Resource & Research Center (RRRC) | 36174222 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-07-29) | 36174222 | 2026-08-29 11:49:55 | 1 | |||||
|
NISAG Resource Report Resource Website |
RRID:RGD_38500209 | Rattus norvegicus | NISAG were stress-sensitive hypertensive rats that exhibited normal systolic pressure during the first weeks after birth. The development of hypertension in these rats is accompanied by increased sensitivity of the hypothalamic-pituitary-adrenocortical and sympathoadrenal systems to stress. | 38500209 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 38500209 | 2026-08-29 11:49:56 | 0 | |||||
|
SD-Hamp em3Jfcol +/- Resource Report Resource Website 1+ mentions |
RRID:RGD_36174223 | Rattus norvegicus | Hamp KO, Sprague-Dawley rats were generated by Transposagen Biopharmaceuticals (Lexington, KY). Four different genetically engineered rat lines, each with different sized Hamp deletions (with or without concurrent insertions), were created using TALEN technology. SD-Hamp em3Jfcol +/- (RGD:36174223) is heterozygous carrying a 20-bp deletion and a 3-bp insertion in exon 2 of the rat Hamp gene. Rat Resource & Research Center (RRRC) | 36174223 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-07-29) | 36174223 | 2026-08-29 11:49:55 | 1 | |||||
|
RCS-Mertkrdyp/LavJcl Resource Report Resource Website |
RRID:RGD_126848751 | Rattus norvegicus | This strain maintained at Japan JCLEA is homozygous at the pink eye (p) locus and homozygous for a deletion in the Mertk gene. CLEA Japan, Inc | 126848751 | congenic | Rat Genome Database (RGD) | RGD | Live Animals (as of 2021-04-28) | 126848751 | 2026-08-29 11:49:57 | 0 | |||||
|
SD-Gnalem1Hpng-/- Resource Report Resource Website |
RRID:RGD_150429817 | Rattus norvegicus | Thehomozygous Gnal mutant rats were created by CRISPR/Cas9. Guide RNA sequences targeting the first exon of the rat Gnal gene isoform 2 were designed. The mutated allele contained a 13- bp deletion in exon1 that corresponded to position 34 to 46 downstream of the translation start point ATG of the Gnal splicing variant 2 was detected resulting in an early stop at position 150 and producing a truncated protein with 50 amino acids. Only 5% of homozygous Gnal knockout mice could survive till maturity | 150429817 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 150429817 | 2026-08-29 11:49:58 | 0 | |||||
|
WI-Ahrem1Hyama-/- Resource Report Resource Website 1+ mentions |
RRID:RGD_15090819 | Rattus norvegicus | The homozygous rats carrying 2 defective Ahr genes. The deletion of part of exon 2 in rat Ahr gene was created by injecting TALEN mRNA containing 5'-TTCTAAACGACACAGAGACCGGCTGAACACAGAGTTAGACCGCCTGGCTA-3' to embryos of JclKud:WI. | 15090819 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 15090819 | 2026-08-29 11:49:57 | 1 | |||||
|
LE-Chrna5em18Pas Resource Report Resource Website |
RRID:RGD_14402419 | Rattus norvegicus | The Zinc Finger Nuclease system was used to create184-bp deletion at the beginning of exon 5 thus created the premature stop coden. The embryos were from breeding of Long Evans from Janvier Labs (RjOrl:LE) and reimplanted to foster mother Dark Agouti (Janvier). Heterozygous rats are currently bred to generate heterozygous and homozygous. | 14402419 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 14402419 | 2026-08-29 11:49:57 | 0 | |||||
|
Wpk -/- Resource Report Resource Website |
RRID:RGD_15017094 | Rattus norvegicus | The wpk mutation was first recognized in 1994 in a colony of outbred Wistar rats at Utrecht University (Utrecht, The Netherlands). In 1996, a breeding pair of test-proven heterozygotes were transferred to the University of Rotterdam (Rotterdam, The Netherlands), and a new subcolony was initiated. This colony has been maintained by brother-sister matings for more than five generations. Individuals heterozygous for the mutant allele were identified in each generation by test-crossing phenotypically normal offspring from known heterozygotes. A single C to T substitution in exon 12 was identified as the mutated allele in the Wpk rat. This mutation converts a proline to a leucine in the protein products(P394L). | 15017094 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 15017094 | 2026-08-29 11:49:57 | 0 | |||||
|
SD-Uoxem1Cya Resource Report Resource Website |
RRID:RGD_150521538 | Rattus norvegicus | The CRISPR/Cas9 system targeting exons 2 to 4 was injected into Sprague Dawley embryos. The resulting mutation was complete deletion of exons 2, 3 and 4. | 150521538 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 150521538 | 2026-08-29 11:49:57 | 0 | |||||
|
SD-Cftrem1Apb Resource Report Resource Website |
RRID:RGD_151356958 | Rattus norvegicus | The CRISPR/Cas9 system was used to target exon 11 to create a deletion at codon F508 which was injected into Sprague-Dawley one-cell embryos (C076 line). One rat had an allele that contained the desired homology-directed repair edited TTT deletion and was designated the Phe508del founder (c.1522_1524delTTT). | 151356958 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 151356958 | 2026-08-29 11:49:58 | 0 | |||||
|
LA-cp/NRll Resource Report Resource Website |
RRID:RGD_40924661 | Rattus norvegicus | This corpulent rat used by Rudolph L Leibel's laboratory was developed at the National Institutes of Health (NIH). It was a congenic strain initially derived by mating a male Koletsky rat that was heterozygous for the corpulent gene (cp/ +) to a female Lister Albany/NIH (LAIN) rat. This congenic carrying the recessive Leprcp (RGD:11570565) identified in in the obese spontaneously hypertensive Koletsky rat. | 40924661 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 40924661 | 2026-08-29 11:49:57 | 0 | |||||
|
SD-Tspoem1Vpl Resource Report Resource Website |
RRID:RGD_150429828 | Rattus norvegicus | Tspo-targeted genome editing in Sprague Dawley rats embryos by microinjecting with optimized and customized ZFNs designed for targeted gene KO. Locus-specific PCR was performed to identify Rat5 founders using the following primer pairs: CKOZFN-F: 50-AGAGCATACTCTTGCCGTCG-30 and CKOZFN-R:50-ACTCCTAAAGGGGTTGCAGG-30; Normal PCRs generated 362 bp for the WT and 273 bp for the mutant,(89 bp deletion). | 150429828 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 150429828 | 2026-08-29 11:49:57 | 0 | |||||
|
SD-Il36rntm1(Myh6-cre)Mhzh Resource Report Resource Website |
RRID:RGD_126925134 | Rattus norvegicus | This line was produced by mating rats carrying Il36rnf/f allele and Myh6-cre-allele. The expression of Il36rn was knockout in cardiomyocytes. | 126925134 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 126925134 | 2026-08-29 11:49:57 | 0 |
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