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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2304203
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Embryo
Alternate IDs: 2304203
Notes: DsRed2/GFP double-reporter transgenic rat driven under a ubiquitous CAG promoter. In this system, DsRed2 expression was replaced with GFP expression after Cre recombinase-mediated excision established at Jichi Medical School. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2304203 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2314414
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 2314414
Notes: LEW/Crl rat embryos were microinjected with an lentiviral single vector system comprising of Insr-specific shRNA construct under the control of H1t promoter
Proper citation: RRID:RGD_2314414 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2314382
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 2314382
Notes: This transgenic strain was established by CLEA Japan, Inc. The construct is as follows: CAG promoter, loxP sequence, neomycin resistance gene, loxP sequence and Ha-ras*G12V (HrasV12). It was injected into Jcl:SD embryos, the transgene is regulated by the Cre/loxP system. Human Ha-ras*G12V oncogene is driven by CAG promoter National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2314382 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2306070
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2017-04-21)
Alternate IDs: 2306070
Notes: Ikeda developed transgenic rats carrying the human growth hormone (GH1) driven by murine Wap promoter, originated from Wistar-Imamichi (Ikeda, 1994). Two lines of this transgenic strain were established named Line 1: characterized by relatively high level of serum Gh1 (high line, NBRPNo.0490), and Line 2: relatively low level of serum Gh1 (low line, NBRPNo.0491). National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2306070 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2306073
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2017-04-21)
Alternate IDs: 2306073
Notes: Ikeda developed transgenic rats carrying the human growth hormone (GH1) driven by murine Wap promoter, originated from Wistar-Imamichi (Ikeda, 1994). Two lines of this transgenic strain were established named Line 1: characterized by relatively high level of serum Gh1 (high line, NBRPNo.0490), and Line 2: relatively low level of serum Gh1 (low line, NBRPNo.0491). National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2306073 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2313734
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 2313734
Notes: Fertilized eggs of NTac:SD were microinjected with a construct containing shRNA cassette containing the insulin receptor under the control of H1 promoter with a tetO site and a cassette driving tetR from CAGGS promoter
Proper citation: RRID:RGD_2313734 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2313735
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 2313735
Notes: Fertilized eggs of NTac:SD were microinjected with a construct containing shRNA cassette containing the insulin receptor under the control of H1 promoter with a tetO site and a cassette driving tetR from CAGGS promoter
Proper citation: RRID:RGD_2313735 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2306023
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 2306023
Notes: Developed by the DEPOSITOR National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2306023 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155663367
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 155663367
Notes: This transgenic model line 733 was made by injecting bacterial artificial chromosome (BAC) RNECO-180E22, into Crl:CD(SD) strain embryos. The BAC clone RNECO-180E22, a kind gift of Helen Skaletsky, is derived from Rattus norvegicus strain SHR chromosome Y.
Proper citation: RRID:RGD_155663367 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=401799619
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2023-09-12)
Alternate IDs: 401799619
Notes: This transgenic strain was created by intracytoplasmic sperm injection (ICSI) mediated DNA transfer. Linearized Acr3-EGFP plasmid DNA (Nakanishi et al., FEBS Lett. 1999; 0.1 micrograms/ml) is mixed with sperm heads of Slc:SD rats for 2 min. The sperm head is microinjected into ovulated oocytes of Slc:SD rat (RGD ID:12910483) and incubated overnight prior to embryo transfer to pseudopregnant females. Resultant pups are examined for correct gene-targeting by genomic PCR, and maintained by crossing the founder with Slc:SD rat. Section of Mammalian Transgenesis Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, Okazaki Aichi 444-8787, Japan. or Division of Mammalian Embryology, Center for Stem Cell Biology and Regenerative Medicine, The Institute for Medical Science, The University of Tokyo, Tokyo108-8639, Japan.
Proper citation: RRID:RGD_401799619 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=329969882
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 329969882
Notes: The heart-specific cre expression plasmid (alpha-MHC-Cre) was produced by inserting the cre coding sequence downstream of the a-MHC (Mgh6) promoter in the a-MHC expression vector. The a-MHC-Cre transgenic rat was generated by microinjection of linearized alpha-MHC-Cre plasmid to Sprague Dawley embryos.
Proper citation: RRID:RGD_329969882 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=329848998
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2023-06-07)
Alternate IDs: 329848998
Notes: This strain is established by injection of modified BAC (cre gene was inserted into the exon 2 of rat Drd2 gene) into Long-Evans rat's fertile eggs.
Detailed information of BAC: Drd2, CH230-11B15 from the CHORI-230 Female Brown Norway rat BAC Library (BACPAC Resources Center, Children?s Hospital Oakland Research Institute)" National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_329848998 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=329848999
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2023-06-07)
Alternate IDs: 329848999
Notes: This strain is established by injection of modified BAC (cre gene was inserted into the exon 2 of rat Drd2 gene) into Long-Evans rat's fertile eggs. " National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_329848999 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598092607
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-03-28)
Alternate IDs: 598092607
Notes: This strain was established by a use of the BAC transgenic method with a technical support from the C.B.S.N resource (Dr. Kazuto Kobayashi, Fukushima Medical University, Dr. Yuchio Yanagawa, Gunma University Graduate School of Medicine). This transgenic rat was transported to The Jikei University School of Medicine, and cre recombinase expression was confirmed by crossing it with a reporter rat (NBRP Rat No: 0734). These rats are maintained in The Jikei University School of Medicine. Background strain: Crlj:WI.
Transgene: Dbh (dopamine beta-hydroxylase: rat), TetR (E.coli), VP16 protein minimal“F”-type activation domain (Herpes simplex virus), 2A (Thosea asigna virus), cre recombinase (P1 Phage), bGlobin polyA (rabbit), loxP (P1 phage). Detailed method (BAC transgenic method): a rat BAC clone was used (CH230-211J22). Combined mRNA for tTA and cre recombinase sequences is transcribed under the control of Dbh promoter. In translation step, the transcript is cut at the 2A peptide sequence, resulting in a separate protein production of tTA and Cre. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_598092607 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598092605
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-03-28)
Alternate IDs: 598092605
Notes: This strain was established by a use of the BAC transgenic method with a technical support from the C.B.S.N resource (Dr. Kazuto Kobayashi, Fukushima Medical University, Dr. Yuchio Yanagawa, Gunma University Graduate School of Medicine). This transgenic rat was transported to The Jikei University School of Medicine, and cre recombinase expression was confirmed by crossing it with a reporter rat (NBRP Rat No: 0734). These rats are maintained in The Jikei University School of Medicine. Background strain: Crlj:WI.
Transgene: Dbh (dopamine beta-hydroxylase: rat), TetR (E.coli), VP16 protein minimal“F”-type activation domain (Herpes simplex virus), 2A (Thosea asigna virus), cre recombinase (P1 Phage), bGlobin polyA (rabbit), loxP (P1 phage). Detailed method (BAC transgenic method): a rat BAC clone was used (CH230-211J22). Combined mRNA for tTA and cre recombinase sequences is transcribed under the control of Dbh promoter. In translation step, the transcript is cut at the 2A peptide sequence, resulting in a separate protein production of tTA and Cre. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_598092605 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=597538592
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 597538592
Notes: For the generation of transgenic rats, the authors used a 190-kb fused AF163864 PAC/AC097478 BAC clone (Yamakado et al., 2012, PMID:22475625). It contained the entire human SNCA sequence (GenBank AF163864), with 30-kb upstream regulatory promoter sequences and a 45-kb flanking downstream region, cloned into pBACe3.6 vector as described previously. Transgenic rats were obtained by injecting the purified BAC fragment into fertilized Sprague–Dawley oocytes at a concentration of 1.5 µg/ml. A founder line displaying the highest integration number of BAC DNA construct was crossedbred to homozygosity.
Proper citation: RRID:RGD_597538592 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405849386
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 405849386
Notes: This is the wild type littermate of the hDNMT3A transgenic rats which were established using zygote microinjection of a bacterial artificial chromosome (BAC). The RP11-159D24 BAC (NCBI-ID:223335, Homo sapiens, GRCh38.p2: Chr. 2: 25,202,642-25,410,145, total length: 207,504 bp) containing DNMT3A (GRCh38.p2: 25,232,961,25,342,590, total length: 109,630 bp) was injected into rat zygotes (Rattus norvegicus, Sprague-Dawley, SD). The offspring were identified with 8 PCR primer-pairs that were specific for the RP11-159D24 sequence to detect positive transgenic ones and wild type littermates that did not carry the human transgene.
Proper citation: RRID:RGD_405849386 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=617256277
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-07-23)
Alternate IDs: 617256277
Notes: Cryopreserved sperm was obtained and recovered for SD-Tg(Camk2a-cre/ERT2)ZiRrrc (RRRC_00688; RGD ID: 13446407), and then back-crossed to the outbred Long-evans (LE) strain for 8 generations. This transgenic strain is a tamoxifen inducible Cre recombinase animal in the Long-evans strain, with targeted cre/ERT2 fusion protein expression in neural populations, and is suitable for crossing with loxP models also in the LE strain. Rat Resource and Research Center
Proper citation: RRID:RGD_617256277 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=632522749
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 632522749
Notes: This transgenic rat strain carrying human NR3C2 was developed on a Sprague-Dawley albino background. The transgene was constructed with the human NR3C2 (also know as MR) under the proximal P1 promotor in the 5′-flanking regions of exons 1alpha.
Proper citation: RRID:RGD_632522749 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10045606
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 10045606
Notes: This transgenic rat was established by microinjection of transgene consisting of Ddx54 gene (NM_001191548.1) driven by CMV promoter (pCMV-Tag2B) derived from cytomegalovirus into Wistar rat (SLC) pronuclear fertile eggs at UNITECH Co., Ltd. in 2007. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_10045606 Copy
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